Basic Information

Insect: Drosophila neotestacea
Gene Symbol: ush
Assembly: GCA_035044365.1
Location: JAWNMD010000361.1:578126-588416[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0069 0.53 11.0 0.0 1 20 213 232 213 234 0.90

2 9 0.0003 0.023 15.3 0.8 1 23 289 311 289 311 0.98

3 9 0.053 4 8.3 1.0 2 21 360 379 360 380 0.92

4 9 0.051 3.9 8.3 2.9 2 21 766 785 765 786 0.93

5 9 0.0095 0.73 10.6 0.0 3 21 835 853 833 854 0.91

6 9 0.0068 0.52 11.1 0.0 2 23 909 930 908 930 0.98

7 9 0.004 0.31 11.8 1.3 1 23 936 958 936 958 0.99

8 9 0.00073 0.056 14.1 0.8 1 23 1024 1047 1024 1047 0.96

9 9 0.43 33 5.4 0.5 2 20 1158 1176 1157 1178 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0069	0.53	11.0	0.0	1	20	213	232	213	234	0.90
2	9	0.0003	0.023	15.3	0.8	1	23	289	311	289	311	0.98
3	9	0.053	4	8.3	1.0	2	21	360	379	360	380	0.92
4	9	0.051	3.9	8.3	2.9	2	21	766	785	765	786	0.93
5	9	0.0095	0.73	10.6	0.0	3	21	835	853	833	854	0.91
6	9	0.0068	0.52	11.1	0.0	2	23	909	930	908	930	0.98
7	9	0.004	0.31	11.8	1.3	1	23	936	958	936	958	0.99
8	9	0.00073	0.056	14.1	0.8	1	23	1024	1047	1024	1047	0.96
9	9	0.43	33	5.4	0.5	2	20	1158	1176	1157	1178	0.91

Sequence Information

Coding Sequence: ATGAAGTTAACACAATGCCAGACACGATTTGTGGATCCTTTGGCTCCCCAGTTGCCCAGTTGCCTTGTGGGCGGTCGCCTAGTGGGCGTGTCGCCGCCCTCACGAATTTACTGTAACAATTCCAAAGATTTAGATGCACACGAGCTGAGCGAggagaagcaacagcagcagcagcaacagttcgAGGAGCAGTCCGAGGACGAACAAGGAGAGAACCAAACCAGCAACGCCTCCGATCAACCCATTGAGACTGACATGGATCAGGAAATGGTCGAGGCTCAATCCGTGCAGGAGGAGCAGCAGAAAGAGGCCGAAAACTCGACGACGCCACCACGTAGTCCAACGCCTGAGCTAGTGCCGAAGCTGGAGAGAATCGAAGAGCCGGCTACACCCCCCTCAGCGGCAGCCTCGCCCAGTCCCCCGCCCACACCTACGCCCATACCCTCGACTGTGCTGCCAAAGCTGCGTCTGAATGCACTACTCGCCTCGGATCCGGCTCTAAAACCAGATGCCAAGGAGTTAAACCTGACAGATGCAAGGTTGTTGGGACCGCCACCTCAGCTGGCAAAGCCCGAGCCGCAGCAGAGTCTACCCGATCCCAGCAGCCTGGTGGAACCACTTCTTAAGCCGGCACGCTTCATGTGCCTACCTTGTGGCATTGCCTTCAGCTCACCCTCGACTCTAGAGGCGCATCAGGCTTATTACTGCTCCCATCGCAGCAAGGAGGGCGACGAGGAGACGGCGTCTGGAGACAAGCTGGCAACTCCAGGGGGAGGAGGCGCCTCTGCGACAggtaacagcagcaatagcgGAGGAGGTGGCAGCTCGGAGCCACCAGCAAAGGTAGCACGCATTGGGAAACAATATGCCTGCACTCAGTGTTCCTACAGTGCCGACAAGAAGGTCTCCCTCAATCGCCACATGCGCATGCATCAGACATCACCAGCTCCTAGTTTGCCCAGCCTTTCCAGCCTCACAGCTAATGGAGTTTCAGGAGGAGTTGGAACTGCTGGCGGTGTTGGAGGAGTTGGAGGCGGAGGCTCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGGTTCAACAATATCAAGACCTATCGCGCCCACAAGCAACACTATTGCAGCTCCCGTCGTAGCGATGGACAGCTGACCCCTAAACCGGAGGCAGGAGTCGGTTCAGGAGCAACAGGTGCTTCAACTGGAGTTTCCGTTGGAGGAAGTGGGGGCAAATTGAGTGGTGCTCACAGTCCGCAGACTAGAAACAAGACGCCGACTCCAGCAatggttgctgctgccgccgccgctgcagctgctgctgctgccgcttcCCTGCAGGTGACGCCACCTCAGCCCTTCCTGGCACTGCCCACCAATCCCATCATCATTGTACCCTGCTCCCTGATTCGTGCCGCCAGCCTAATACCAGGACCACTCACCACCTCCACGTCGGGCATTGTTAATCCAGAGTCCACGTGCTTTACCCTCGACAATGGCGCCTTGAAGCCATTGGCCACGGCTCTGAATATTAATGCCCTGGCCGGGAATGTCACTCCCTCTCCGTTGCCCACCAGCAGCCAGCAAACAATTCCAGCTCTGGAACCAGATCGTCAGACAGGCACCAGCATCAACTCCCTTGATGGAGATGCCAAGAATAGTCCACCGGAACCCAAGCGCAAGGAAGCAGGCACTCGTGAGTCTACCCCTCTGGATCTGTCATTGCGACGTTCTCCTATTTCAGCGTTATTGCAACGTCAGCGTCTGGTGCGCTCTGCCGCAGCGCTGCTTGAGGCAGAGGAGGCACTGCTGAGTGCAGGCAAGGAGAATGTGGAGAGTGGAGGCAGCGTGACGCCGGAACAGATCGTGTGTGCTCCATCGCTGCCCAGTAGCCCTTCGATGAGTCCCTCTCCGAAGCGACGAACTGTTAGTCCACGTAGTTCTGGAGCAGGCAGCGCTGCTTCCATGTCGCCTCCTGCTTTGGGTGTGGGCGTGCCACATCTGCTGGAGAATCTGCCACCATTGCGTTCCATGTTGCCCGCTGACTTTGCGTTATCCGAATCCCTGTTGGCAAAGACTAATCCTGAGCTGGCTCTGAAATTGGCAgcggctgcagctgcagctgtggCAGGAAGCAGCAGCGCAGAGTTGGCGAGTAAACTGGGATTCCCCACAAGAGGAGATGCCTCAGGAGCATCTGGAGCCACTGCAGCACCAAATGCAGCTACAAATGCGCCTAGTGGACAACCTCAGATCTATGTAAAGCAAGGCGTCTCCAAGTGCAAGGAATGCAACATTGTCTTTTGCAAATATGAAAACTATTTGGCTCACAAACAGCATTATTGCTCCGCTCGCAATCAGGAGACAAGCGAAGGGGATGCGAAGAGCTCAAACACACCTCCAAGTGGTGGAGGAGCAGCTGGAGGAGGCGTGGCTGGTGCCTCCACGGCGGAGACAACACCTGTGGCGTATCAACAATTGATCTGTGCCGCCTGTGGCATCAAGTATACTTCGTTGGACAATCTACGTGCTCATCAGAATTACTATTGCCCCAAAGGTGGTGCAGCAGCCACACCCGCTGATCCGCAACTCTCGCTGCCCAAGGAGAAGTGTGGCAAGTGCAAGACCCTCCACGAACATGGTCAGCCTTGTCCTCCTCCAGTTGCACCACAAATGCCGCCAGTTGCAGTCTCGAATAGCGTCAACAAGTGTCCCGTCTGTGGGGTTGTGAGTCCCACAGCAGCACTGGCCAGAAAGCACATGGAGATGCACGGCACGGTGAAGGCGTTCCGTTGCAGCATCTGTCAGTACAAGGGAAATACATTGCGTGGCATGCGCACTCACATACGCACCCATTTTGACAAGAAGACCAGCGATGTGAATGAAGAGCATTACATGACCTGCATATTTGAGGAAGAtgctgttcctgctcctgctcctgtgcCGACAGCTGCTTTAGCCCAGAGTGTGGGTATGGGACTGGATGTGCCTACTGTGGCAACTTCTCAAGAGCAATTGGAGCAACAACAGGCGCAGCATCCGCCACAGATCTTCAACTGCGACTACTGCAACTATGCATCCACCTACAAGGGCAATGTGCTGCGCCACATGAAACTGTTGCATCCAAACGTGGCAATCAGTTCGCCCTCCATTTCCCCAGAGTCACGTGAGCAGGACAATATTCCTCAAGCTTTACCCGAAGTAACGCTAGTAAATGGAGATCGGGAGACGGCAGCCGTAGCTAGTTTCCACATTAAGTCGGAGCCTTTAGAGCAACAACCTGTGGCAACACTGAGTCTCGTGCATGAGAACAACAATTCACCCATCGGGACACCACACACCCACATCAAGGCCGAGCCCATGGATATGGGAATGGAAGTGTCACCTCCGTCACTGCCTCCGCCAGTAACAAATTCACCTCTGGGTCCAAGTGCCGCTGAGGCCATGAAGAAATACTGCTCCACCTGCGACATATCGTTCAACTATGTGAAAACCTATCTGGCCCACAAGCAGTTCTATTGTAAGAGCAAGTTGCATCGACCCGAGGCGAATGATAGCCCCAGTCCAAATCCCGTGCCCAAcgagctgctgttgctccagAAGAACAAGGAGAATCTACAGGAGGCGGCCATTTGA
Protein Sequence: MKLTQCQTRFVDPLAPQLPSCLVGGRLVGVSPPSRIYCNNSKDLDAHELSEEKQQQQQQQFEEQSEDEQGENQTSNASDQPIETDMDQEMVEAQSVQEEQQKEAENSTTPPRSPTPELVPKLERIEEPATPPSAAASPSPPPTPTPIPSTVLPKLRLNALLASDPALKPDAKELNLTDARLLGPPPQLAKPEPQQSLPDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRSKEGDEETASGDKLATPGGGGASATGNSSNSGGGGSSEPPAKVARIGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSLPSLSSLTANGVSGGVGTAGGVGGVGGGGSLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGVGSGATGASTGVSVGGSGGKLSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAASLQVTPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNVTPSPLPTSSQQTIPALEPDRQTGTSINSLDGDAKNSPPEPKRKEAGTRESTPLDLSLRRSPISALLQRQRLVRSAAALLEAEEALLSAGKENVESGGSVTPEQIVCAPSLPSSPSMSPSPKRRTVSPRSSGAGSAASMSPPALGVGVPHLLENLPPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSSAELASKLGFPTRGDASGASGATAAPNAATNAPSGQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQETSEGDAKSSNTPPSGGGAAGGGVAGASTAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPADPQLSLPKEKCGKCKTLHEHGQPCPPPVAPQMPPVAVSNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAVPAPAPVPTAALAQSVGMGLDVPTVATSQEQLEQQQAQHPPQIFNCDYCNYASTYKGNVLRHMKLLHPNVAISSPSISPESREQDNIPQALPEVTLVNGDRETAAVASFHIKSEPLEQQPVATLSLVHENNNSPIGTPHTHIKAEPMDMGMEVSPPSLPPPVTNSPLGPSAAEAMKKYCSTCDISFNYVKTYLAHKQFYCKSKLHRPEANDSPSPNPVPNELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00510792; iTF_00569257; iTF_00478996; iTF_00583951; iTF_00519444; iTF_00803125; iTF_00608727; iTF_00803895; iTF_00805478; iTF_00579546; iTF_00471132; iTF_00537788;
90% Identity: iTF_00608727;
80% Identity: -