Basic Information

Insect: Drosophila pruinosa
Gene Symbol: ush
Assembly: GCA_018150935.1
Location: JAECWR010000023.1:6865536-6874564[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0058 0.48 11.0 0.0 1 20 201 220 201 222 0.90

2 9 0.00025 0.02 15.3 0.8 1 23 277 299 277 299 0.98

3 9 0.045 3.7 8.3 1.0 2 21 356 375 356 376 0.92

4 9 0.043 3.5 8.3 2.9 2 21 751 770 750 771 0.93

5 9 0.008 0.66 10.6 0.0 3 21 818 836 816 837 0.91

6 9 0.0058 0.47 11.1 0.0 2 23 903 924 902 924 0.98

7 9 0.0034 0.28 11.8 1.3 1 23 930 952 930 952 0.99

8 9 0.00061 0.05 14.1 0.8 1 23 1013 1036 1013 1036 0.96

9 9 0.36 30 5.4 0.5 2 20 1149 1167 1148 1169 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0058	0.48	11.0	0.0	1	20	201	220	201	222	0.90
2	9	0.00025	0.02	15.3	0.8	1	23	277	299	277	299	0.98
3	9	0.045	3.7	8.3	1.0	2	21	356	375	356	376	0.92
4	9	0.043	3.5	8.3	2.9	2	21	751	770	750	771	0.93
5	9	0.008	0.66	10.6	0.0	3	21	818	836	816	837	0.91
6	9	0.0058	0.47	11.1	0.0	2	23	903	924	902	924	0.98
7	9	0.0034	0.28	11.8	1.3	1	23	930	952	930	952	0.99
8	9	0.00061	0.05	14.1	0.8	1	23	1013	1036	1013	1036	0.96
9	9	0.36	30	5.4	0.5	2	20	1149	1167	1148	1169	0.91

Sequence Information

Coding Sequence: ATGCGAGACACGATTTCTCGACTCCTTGGCCAGTTGGCTGTGGGCGGTCGCGTGGTGGGCGTGTCGCCGCCCTCACGAATTCAGTATTCCAAAGAATTAGGCGCACACGAGCTGAGCGAGGAGAAGGAGCATCAAGAACACCAGCAGTTCGAGGAGCAGCCAGAGGAGGAGCACGAAGAGAACCAAATGAGCAACAGCTCTGACCAGCCCATCGAGACTGACATGGATCAAGACATGGTCGAGGCGCAAGCAGCGCAAGAGGAGCAGCAAAAAGAGGCAGACAACTCGACGACGCCACCGCGCAGTCCAACGCCCGAGCTGGTGCCCAAGCTGGAGAGGATTGAGCAGCCCGCTACACCACCTTCGGCAGCAGCCACGCCCAGTCCCCCGCCCACACCCACACCCACACCCAATGTACTGCCCAAGTTGCGACTTAATGCGCTGCTCGCCTCAGATCCGGCGCTCAAGCCAGACGCCAAGGAGCTGCACCTAACAGATGCACGTCTGCTGGCACCGCCGCCACAGTTGCCAAAGCCTGAGCCACCACAGAGTCTAACAGATCCCAGCAGCCTTGTAGAGCCACTGCTGAAGCCAGCACGCTTTATGTGCCTGCCATGCGGCATTGCCTTTAGCTCGCCCTCGACGCTGGAGGCGCATCAGGCCTACTACTGCTCCCATCGCAATAAGGACGCTGATGAGGAGGGTGCATCTGGCGATAAGCTAGCATCCTCAGGCGGTTCAGGTTCCTCTGCCACCGGCAACAACAGCAACAGCGGTGGAGGAGGCAGCTCAGAGCCTCCAGCGAAGGCGGCACGCACTGGGAAGCAATATGCGTGCACACAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAACCGCCACATGCGCATGCACCAATCCTCGCCAGCGCCCAGTCTGCCTAGCCTCGCCAGCCTCACAGCCAATGGAGTCACAACAGGAGTTGGCGTCGGAGTTGGAGTTGGAGGAGCTGGCGGAGTGGGAGTCGTTGGCGTAGGCGGTGCGGGATCGCTCGAGGAGAGCTCTAGTCAACAAATTGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTATCGCGCCCACAAGCAGCACTACTGCAGCTCCCGTCGCAGTGACGGACAGCTGACCCCCAAGCCAGAGGCAGGCGTCGGACCCGGTACACCATCAAGCGGCGTAGGAGCTGCCGTCGGAACTGGCAAGCTGAGCGGAGCACACAGTCCGCAGACCCGCAACAAGACGCCGACTCCGGCAATGGTTGCTGCTGCTGCAGCCGCTGTGGCCGCCGCCTCGCTCCAGGTGACGCCCCCTCAACCCTTCCTGGCACTGCCCACCAATCCCATCATCATTGTGCCCTGCTCGCTGATCCGAGCGGCCAGCCTAATTCCGGGACCACTCACCACCTCGACTTCGGGCATAGTTAATCCCGAGTCCACATGCTTCACCCTCGACAATGGCGCCTTAAAGCCCCTCGCCACGGCGCTCAACATCAACGCCCTGGCCGGAAACGTAACGCCCACCCCGATGCCCAGCAGCAGCCAGCAGACGATTGCAGCGCTGGAACCGGAACGTCAGCCTGTCAATAATGAGACGGAAGCCAAGAGCAGTCCGCCGGAACCCAAGCGTAAGGAAGCGGGAGGCACTCGCGAGTCTACCCCGCTGGATCTGTCCTTACGACGTTCCCCCATCTCGGCGCTGCTACAGCGACAGCGTCTCGTGCGCTCTGCTGCCGCGCTGCTCGAGGCAGAGGAGGCGCTACTAGCTGCAGGCAAGGAGAACGTGGAGAGTGGCGGCAGCTTGACCCCGGAGCAAATCGTCTGTGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGACGTGCCGTCAGCCCACGCAGCTCTGGCGCCGGCAGTGCTGCCTCCATGTCGCCCCCTTCCCTGGGAGTGCCACATTTGCTGGACAATCTGCCGCCACTGCGTTCCATGCTGCCGGCCGACTTTGCTCTCTCTGAGTCGCTGCTGGCCAAGACCAATCCCGAGCTAGCGCTCAAGCTGGCGGCGGCTGCAGCTGCCGCCGTGGCTGGCACCAGTCCTGCCGAGCTGGCCAGCAAGCTGGGCTTTCCAACGCCCGGAGCAGCCCCCGGGGCGGCAGCCAACGCACCTGCAGCGGGAGCAGCGAATGCGCCAAGTGGACAGCCTCAGATCTATGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATAGTGTTCTGCAAGTACGAGAACTATCTGGCCCACAAGCAGCACTACTGCTCCGCCCGCAACCAGGAGGCAGTAGAGGGGGATGCCAAGAATGCTAGCTCCCCTCCCGGCGGAGCAGCAGCTGTTGGGGCTGGAGCTGCCTCCGCGGCAGAAACCACGCCAGTGGCGTACCAACAACTGATTTGTGCCGCCTGCGGCATCAAGTACACCTCGCTGGACAACCTGCGTGCCCATCAGAACTACTACTGTCCCAAAGGAGGAGCAGCGGCCACTCCCGCTGATCCCTCACAGCTGCCGCAGCCCAAGGAAAAATGCGGCAAATGCAAGACACTCCACGAGCATGGTCAGCCCTGTCCGCCACCCACAGCGCCCCAGCTGCCAACTATGACTGGAGCCGGATCGGGATCGGGATCTAGCGCTTCCTCGAATAGCGTGAACAAGTGTCCTGTTTGCGGTGTGGTCAGTCCCACGGCAGCGCTCGCCAGGAAGCACATGGAGATGCATGGCACGGTGAAAGCTTTCCGCTGTAGTATCTGCCAGTACAAGGGCAACACCCTGCGCGGCATGCGCACCCACATCCGCACCCACTTTGACAAGAAGACCAGCGATGTCAATGAGGAGCACTATATGACCTGCATCTTCGAGGAAGAAGCCGCTGCTCCCACTGCCGTGCTGGCCCAAGGACTGGCACTCGATATGCCCAGCAACGCAGCAACGCCTCAAGAGCAACTGGAGCAGCAGCAGCAGGCGCAGCATCCTTCTCAGATCTTCAACTGTGACTACTGCAACTATGCGTCCACCTACAAAGGCAATGTGCTGCGCCACATGAAGCTACTGCATCCGCACGTGGCCATCAGCTCGCCCTCCATTTCACCGGAGTCGCGTGAGCAGGACATCAATCCGCATGCCGAAGTGGCGCTCGTCAATGGCGACAGGGAGAGCGCAACCATTGCCAACTTCCACATCAAATCGGAACCACTGGAGCAACAGTCCGGGGCAACGCTTAGTCTGGTGCACGAGAACAATAACTCGCCCATTGGCACGCCACATACACACACCCACACCCACATTAAGGCCGAGCCCATGGACATGGGCATTGATGTGTCGCCCCCCTCACTGCCACCGCCAGTGTCCAACTCTCCGCTGGGCCCCAGCGCTGCCGAGGTCATGAAGAAGTACTGTTCCACCTGCGACATATCCTTCAACTATGTGAAGACCTATCTGGCCCACAAGCAGTTCTACTGCAAGAGCAAGCTGCATCGGCCCGAGGCCAATGATAGCCCCAGTCCCAATCACCTGGGTGCCGCAGTTCCACTGCAGTCGCCCAGCGAACTGCTGCTGCTCCAGAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MRDTISRLLGQLAVGGRVVGVSPPSRIQYSKELGAHELSEEKEHQEHQQFEEQPEEEHEENQMSNSSDQPIETDMDQDMVEAQAAQEEQQKEADNSTTPPRSPTPELVPKLERIEQPATPPSAAATPSPPPTPTPTPNVLPKLRLNALLASDPALKPDAKELHLTDARLLAPPPQLPKPEPPQSLTDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEEGASGDKLASSGGSGSSATGNNSNSGGGGSSEPPAKAARTGKQYACTQCSYSADKKVSLNRHMRMHQSSPAPSLPSLASLTANGVTTGVGVGVGVGGAGGVGVVGVGGAGSLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGVGPGTPSSGVGAAVGTGKLSGAHSPQTRNKTPTPAMVAAAAAAVAAASLQVTPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNVTPTPMPSSSQQTIAALEPERQPVNNETEAKSSPPEPKRKEAGGTRESTPLDLSLRRSPISALLQRQRLVRSAAALLEAEEALLAAGKENVESGGSLTPEQIVCAPSLPSSPSMSPSPKRRAVSPRSSGAGSAASMSPPSLGVPHLLDNLPPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGTSPAELASKLGFPTPGAAPGAAANAPAAGAANAPSGQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEAVEGDAKNASSPPGGAAAVGAGAASAAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPADPSQLPQPKEKCGKCKTLHEHGQPCPPPTAPQLPTMTGAGSGSGSSASSNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEAAAPTAVLAQGLALDMPSNAATPQEQLEQQQQAQHPSQIFNCDYCNYASTYKGNVLRHMKLLHPHVAISSPSISPESREQDINPHAEVALVNGDRESATIANFHIKSEPLEQQSGATLSLVHENNNSPIGTPHTHTHTHIKAEPMDMGIDVSPPSLPPPVSNSPLGPSAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKSKLHRPEANDSPSPNHLGAAVPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558210;
90% Identity: -
80% Identity: -