Basic Information

Insect: Drosophila acutilabella
Gene Symbol: ush
Assembly: GCA_035046005.1
Location: JAWNOK010000074.1:1106906-1112409[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0078 0.61 10.9 0.0 1 20 328 347 328 349 0.90

2 9 0.00034 0.026 15.2 0.8 1 23 407 429 407 429 0.98

3 9 0.06 4.7 8.1 1.0 2 21 487 506 487 507 0.92

4 9 0.058 4.5 8.1 2.9 2 21 889 908 888 909 0.93

5 9 0.011 0.84 10.4 0.0 3 21 962 980 960 981 0.91

6 9 0.0078 0.6 10.9 0.0 2 23 1048 1069 1047 1069 0.98

7 9 0.0046 0.35 11.6 1.3 1 23 1075 1097 1075 1097 0.99

8 9 0.00083 0.064 14.0 0.8 1 23 1157 1180 1157 1180 0.96

9 9 0.4 31 5.5 0.4 2 20 1293 1311 1292 1313 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0078	0.61	10.9	0.0	1	20	328	347	328	349	0.90
2	9	0.00034	0.026	15.2	0.8	1	23	407	429	407	429	0.98
3	9	0.06	4.7	8.1	1.0	2	21	487	506	487	507	0.92
4	9	0.058	4.5	8.1	2.9	2	21	889	908	888	909	0.93
5	9	0.011	0.84	10.4	0.0	3	21	962	980	960	981	0.91
6	9	0.0078	0.6	10.9	0.0	2	23	1048	1069	1047	1069	0.98
7	9	0.0046	0.35	11.6	1.3	1	23	1075	1097	1075	1097	0.99
8	9	0.00083	0.064	14.0	0.8	1	23	1157	1180	1157	1180	0.96
9	9	0.4	31	5.5	0.4	2	20	1293	1311	1292	1313	0.90

Sequence Information

Coding Sequence: ATGTTGCTGGCGTGGAGTCTGGCGAGCAAACACTTTACGTGTGCTGCTTATCGCGCGCCAATCGAAGGCAATAAATATCTTACAAATAAGCAGAATGCGCAGGAATGCGCAGAGACCTCAAATGTCAGCTTGGCCGCTCTAATCATCAACGTTTGGGGACCGTTGGACCATTGGACTCAGGGACCCATCGAACGTTGGACTCGTGGACCAGCGCTAGTGACCACCATGCGCTTTTCCACTCCACTCGTCGGTTTTCCACGTAATCCGACAGCGTTGAGATGCGTTCGCGGGATAAACAAGTTGGAACTGTTCGAGGCAGAGACCAAACGGGCCAATGCTCAAATGGCTCAAATGGTCGATTGCTCGATTGGTCGATTGGTCGACAACCTTAAACCCCTTACCCCCTTCCTTGTCTTCCTCTTGGACAACGGCGCATTGTTTTCACAGCTGCCTGTCGCTTCACTCGCACCGCTGACAATTTATTCCAAAGATTTAGATGCACACGAGATGAGCGAGGAGAAGCAACCGCAAGAGCAGTTCGAGGATCAACCCGAGGACGAGCAGGCAGAGAACCAAACCAGCAACTCCTCCGATCAACCCATTGAGACTGACATGGATCAGGAAATGTTGGAGGATCAGGTCGTGCAGGAGGAACAGCAGAAAGAGGCTGATAATTCGACGACACCGCCACGTAGTCCGACGCCCGAGCTTATACCCAAGTTGGAACGTCCAGAGGAACCGGCCACGCCACCCTCTGCGGCCGCCACGCCCAGTCCTCCGCCTACACCCACATTGGTGCTGCCCAAACTGCGTCTCAATGCGCTGCTCGCCTCGGATCCGGCACTGAAACCGGACGCCAAGGAGCTGAACCTGCAGGATGCACGCCTGCTGGGTCCACCCGCTCAGCTATCAAAGCCCGAGCCGCCACAGAGTCTAGCCGATGCCAGCAGCCTGGTAGAGCCGCTACTGAAGCCAGCGCGCTTCATGTGCCTGCCCTGCGGCATCGCCTTCAGTTCGCCCTCAACGCTGGAGGCACATCAGGCCTACTACTGTTCCCATCGCAACAAGGAGGCCGACGAAGAGACGGCGTCGGGGGATAAGGCCTCCTCGGGATCAGGTGGTAATGCTGCGACTGGCAGCAGCaccagtggcagcagcaacaacgtgGGAGGCAGCAGCTCAGAGCCACCAGCGAAGATGGCACGCACGGGAAAGCAGTATGCCTGCACCCAATGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAATCGGCACATGCGCATGCACCAGACCTCCCCAGCTCCCAGTCTGCCCAGCCTCTCTAGCCTAACAGCTAATGGAGTGGTCGGAGGAGGCATCGGAGGTGGAATTGTCGGAGGAGTTGTGGGTGGAGGTGCAGGTGCAGGCGTTGTCGTAGCAGGTGCGCTCGAGGAGAGCCCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATTCGGTTCAACAACATTAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCCCGACGCAGCGATGGCCAGCTGACGCCCAAGCCGGAAGCGGGAGGAGCTGGCGCAGTGGGTGGAGGATCGTCTACAACCCCCGGAGCTTCTGTGGGTGGAGCGACTGCTGGCAAATTGAGTCCACAGACGCGCAACAAGACGCCAACGCCTGCCATGgttgcggctgctgcggccgctgcagctgcagctgcggcagccTCACTGCAGGTGGCGCCACCACAGCCCTTTCTGGCACTGCCCACCAATCCCATCATTATAGTTCCCTGCTCGCTGATTCGTGCCGCCAGCCTCATACCGGGACCACTCACCACCTCTACGTCGGGTATTGTCAACCCAGAGTCCACATGCTTCACCCTCGACAATGGCGCCTTGAAACCTTTGGCCACCGCTCTGAATATCAACGCCTTGGCTGCCAATGTCACGCCCTCGCCATTGCCCAGCAGCAATCCTCCAACGGAGCCCGATCGTCCCAGTGGCAACAGCGGGAACTCTCTTGAGGCGGAGACCAAGAACAGCACAGTCGAACCCAAGCGCAAGGAGGCGTCAGGCACTCGTGAGTCTACACCTCTGGATCTATCCCTGCGTCGTTCGCCCATCTCtgcgctgctgcagcggcagcgtcTGGTGCGCTCtgctgcagcgctgctcgAGGCAGAGGAGGCGTTACTCGCAGCTGGCAAGGAGAACATGGAAAGCGGTGGCAGCGTGACACCGGAACAGATCGTATGCGCTCCCAGCCTGCCCAGCAGCCCCTCAATGAGCCCCTCGCCAAAGCGTCGCGTGATCAGTCCCCGCAGCTCTGGTGCCGGTAGTGCTGCTTCCATGTCGCCCCCGGCGCTGGGTGTGGCCGTGCCACACCTACTGGACAATCTGCCGCCCTTGCGTTCCATGCTGCCTGCCGATTTTGCGCTCTCCGAATCCCTGCTGGCTAAAACTAATCCCGAATTGGCGCTTAAATTAgctgcagcagccgctgctgctgtcgcggGCAGCAGCCCCGCCGAGTTGGCCAGCAAGTTGGGTTTTCCACCGCCAGGTGGTGccactgcagctgctggaACAGCTGTGCCGAATTCCGGAGCGAATGCGCCGAGTGGACAGCCCCAGATCTATGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATCGTGTTCTGCAAGTATGAGAACTACTTGGCCCACAAGCAGCACTACTGCTCCGCCCGCAACCAAGAGGCGGGCGAAGGCGAGGCCAAGAACTCGAATACACCGCCAGGTGGCGTTGGAGTGGGCGCTGGAGCTGGTGGTGGGGGCGTGTCCGGTGCCTCGACAGCGGAGACGACTCCGGTGGCGTATCAGCAACTGATCTGCGCTGCCTGTGGCATCAAGTACACCTCGCTGGACAACCTGCGTGCTCACCAGAACTACTACTGCCCCAAAGGTGGCGCCACCGCTGCATCTGCCTCCGCCGCTGCTTCCTCAGCTGAACCCCAACTGACCCTGCCCAAGGAGAAGTGCGCCAAGTGCAAGACTCTGCATGAACACGGCCAGCCATGCCCACCGCCTCCCGCAGCGCCACAGCTGCCGCCAATGGCCGCCAGTGGCGCCACCTCAAACAGCGTTAACAAGTGTCCCGTCTGCGGTGTGGTCAGTCCCACCGCTGCCCTGGCCCGCAAGCACATGGAGATGCACGGCACGGTGAAGGCATTCCGCTGCAGCATCTGCCAGTACAAGGGGAACACTCTGCGTGGGATGCGCACCCACATTCGCACCCACTTCGACAAGAAGACCAGCGACGTTAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGACTCTGGCGCTGCACCGCCGACGGCTGCGTTGGCAGCCAACCTGCCACTGGGATTGGATGTGAGCACGCCCCAATTAGAACAGctggagcaacagcagcagcatccgTCGCAGATCTTCAACTGCGACTATTGCAACTACGCATCCACCTACAAAGGCAATGTGCTACGTCACATGAAACTGTTGCACCCACACGTGGCAATAAGTTCCCCCTCGATTTCCCCCGAAACACGTGAAcaggacaacaacaatccgCATCCTCAGGACGCAGTAACGCTCGTCAATGGTGATCGGGAGGCAACCAGCCTAGCCAACTTCCATATCAAAACGGAGCCGCTGGAGCAGCAGCCTGTGGCCACCTTGAGTCTGGTGCACGAGAACAACAACTCACCGATTggcacaccacacacacacattaaggCTGAGCCAATGGAGTTGGGCGTGGATGTGTCACCGCCATCGCTGCATGTACCGCCTGTGGCTAGTTCACCGCTGGGTCCCAGTGCCGCTGAAGCGATGAAAAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAGACCTATCTGGCCCACAAGCAGTACTACTGCAAGAATAAACTGCATCGTCCTGAGGCCCATGACAGCCCCAGTCCCAATCCGGTGCCCAATGAGCTGCTGCTACTCCAGAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MLLAWSLASKHFTCAAYRAPIEGNKYLTNKQNAQECAETSNVSLAALIINVWGPLDHWTQGPIERWTRGPALVTTMRFSTPLVGFPRNPTALRCVRGINKLELFEAETKRANAQMAQMVDCSIGRLVDNLKPLTPFLVFLLDNGALFSQLPVASLAPLTIYSKDLDAHEMSEEKQPQEQFEDQPEDEQAENQTSNSSDQPIETDMDQEMLEDQVVQEEQQKEADNSTTPPRSPTPELIPKLERPEEPATPPSAAATPSPPPTPTLVLPKLRLNALLASDPALKPDAKELNLQDARLLGPPAQLSKPEPPQSLADASSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKEADEETASGDKASSGSGGNAATGSSTSGSSNNVGGSSSEPPAKMARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSLPSLSSLTANGVVGGGIGGGIVGGVVGGGAGAGVVVAGALEESPSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGGAGAVGGGSSTTPGASVGGATAGKLSPQTRNKTPTPAMVAAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAANVTPSPLPSSNPPTEPDRPSGNSGNSLEAETKNSTVEPKRKEASGTRESTPLDLSLRRSPISALLQRQRLVRSAAALLEAEEALLAAGKENMESGGSVTPEQIVCAPSLPSSPSMSPSPKRRVISPRSSGAGSAASMSPPALGVAVPHLLDNLPPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSPAELASKLGFPPPGGATAAAGTAVPNSGANAPSGQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEAGEGEAKNSNTPPGGVGVGAGAGGGGVSGASTAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGATAASASAAASSAEPQLTLPKEKCAKCKTLHEHGQPCPPPPAAPQLPPMAASGATSNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDSGAAPPTAALAANLPLGLDVSTPQLEQLEQQQQHPSQIFNCDYCNYASTYKGNVLRHMKLLHPHVAISSPSISPETREQDNNNPHPQDAVTLVNGDREATSLANFHIKTEPLEQQPVATLSLVHENNNSPIGTPHTHIKAEPMELGVDVSPPSLHVPPVASSPLGPSAAEAMKKYCSTCDISFNYVKTYLAHKQYYCKNKLHRPEAHDSPSPNPVPNELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558210;
90% Identity: iTF_00478996;
80% Identity: -