Basic Information

Insect: Hirtodrosophila confusa
Gene Symbol: ush
Assembly: GCA_035043065.1
Location: JAWNNI010000212.1:955343-961108[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.059 4.8 8.3 0.0 1 20 209 228 209 230 0.89

2 9 0.00034 0.028 15.3 0.8 1 23 285 307 285 307 0.98

3 9 0.061 5 8.2 1.0 2 21 352 371 352 372 0.92

4 9 0.059 4.8 8.3 2.9 2 21 757 776 756 777 0.93

5 9 0.011 0.9 10.6 0.0 3 21 825 843 823 844 0.91

6 9 0.0079 0.65 11.0 0.0 2 23 913 934 912 934 0.98

7 9 0.0046 0.38 11.8 1.3 1 23 940 962 940 962 0.99

8 9 0.00084 0.069 14.1 0.8 1 23 1025 1048 1025 1048 0.96

9 9 0.37 30 5.8 0.7 2 20 1158 1176 1157 1178 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.059	4.8	8.3	0.0	1	20	209	228	209	230	0.89
2	9	0.00034	0.028	15.3	0.8	1	23	285	307	285	307	0.98
3	9	0.061	5	8.2	1.0	2	21	352	371	352	372	0.92
4	9	0.059	4.8	8.3	2.9	2	21	757	776	756	777	0.93
5	9	0.011	0.9	10.6	0.0	3	21	825	843	823	844	0.91
6	9	0.0079	0.65	11.0	0.0	2	23	913	934	912	934	0.98
7	9	0.0046	0.38	11.8	1.3	1	23	940	962	940	962	0.99
8	9	0.00084	0.069	14.1	0.8	1	23	1025	1048	1025	1048	0.96
9	9	0.37	30	5.8	0.7	2	20	1158	1176	1157	1178	0.91

Sequence Information

Coding Sequence: ATGCGCAGAGCTCGCAGAGAAGCCCAGGATCGGAcgagactgggactgggattgGGCAGGGAGATGGAGATGCAGCATGGAGATGCTGTCGATTGTTCACATTCCAAAGATTTAGGCGCGCACGAGCTGAGCGaggagaagcagcagcagcagctcgagGAGCAGTCCGACGAAGAGCACGGGGAGAACCAAACTAGCAACGCCTCCGATCAGCCCGTAGAGACGGACATGGATCAGGACATGATCGAGGCCCAGGCAGTGCAGGAGGCcaacgagcagcagcagcaggagaaaCAGAGGGAAACCGACAACTCGACGACGCCACCGCGTAGTCCAACGCCAGAGCTGGTGCCCAAGCTGGAGAGAGCTGAGCAGCCGGCCACGCCGCCCTCAGGGGCAGCCACGCCCAGCCCcccgcccacgcccacgcccatgCCCACTACTGTGCTGCCAAAGCTGCGCCTCAATGCGCTACTCGCCTCCGATCCGGCCCTGAAGCCGGACGCCAAGGAACTGAACCTGTCCGATGCACGCCTGCTGGGTCCACCCCCGCAACTGGCCAAGCCCGAGCAAAGCCTACCAGATCCTAGCAGCCTCGTGGAGCCGCTCCTGAAGCCGGCGCGCTTCATGTGCCTGCCCTGCAGCATTGCCTTCAGCTCCCCCTCAACGCTGGAGGCGCACCAAGCCTACTACTGCTCCCATCGCAACAAGGAGACCGACGAGGAGACACCCGCCGGCGACAAAGCCACAACCACAGCCGGGGGTGGCGCCTCCGCcacagccaacagcagcaacagcggcggcggcgccaGCTCGGAGCCACCCGCCAAGCAGGCCCGCACTGGGAAGCAGTACGCCTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTGAACCGGCACATGCGCATGCACCAGACCTCGCCGGCCCCCAGCCTGCCCAGCTTGTCCAGCCTGCCCAGCCTGGCCTCCCTGACGGCCAATGGGGTCTCAGCCGCTGTCGGCGCCGGCTCCCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGGTTCAACAACATCAAGACCTACCGCGCCCACAAGCAACACTACTGCAGCTCCCGACGCAGCGATGGCCAACTGACGCCCAAGCCGGAGGCAGGCGCCGCCGGAACCGGAACTGGCGTCTCAGTGGGAGCTGGAGCGGGCAAGCTGAGTGGCGGCCACAGTCCACAGACGCGCAACAAGACGCCCACGCCAGCAATGgttgctgcagcagccgcagcagctgctgccgctgccgcctcGCTGCAGGTGGCGCCGCCCCAGCCCTTCCTGGCACTGCCCACCAACCCCATCATCATTGTGCCCTGCTCGCTCATACGTGCAGCCAGCCTGATTCCAGGACCGCTCACCACCTCCACGTCGGGCATTGTTAATCCCGAGTCCACGTGCTTTACGCTCGACAATGGGGCCTTGAAACCGCTGGCCACGGCACTGAATATTAATGCGCTGGCGGgaactgccacgcccacgcccacgcccatgGCCAGCAGCAATCAGCTGCCCATTCCCGCCCTGGAGCCAGATCGTCAGCCCGCAAGCAGCGGGAGCGCCTTGGAAGCGGAGGCCAAGAGCAGCCCGCCGGAGCCAAAGCGCAAGGAAACCGGCGGCACTAGAGAATCTACGCCACTGGACTTGTCGCTGCGACGCTCGCCCATTTcggcgctgctgcagcgccaGCGTCTGGTGCGGTCCGCAGCTGCGCTGCTGGACGCCGAGGAGGCGCTCCTGGCTGCGGGTAAGGAGAATATGGAGAggggcggcagcggcggcagcgtgACGCCGGAGCAAATCGTATGCGCCCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGTCGCGCTGTCAGTCCTCGCAGCTCCGGCGCAGGCAGCGCTGCCTCCATGTCGCCCCCGACGCTGAGCGTGGGTGTTGGCATGCCACATCTGCTGGACAGCCTGCCGCCGCTGCGCTCCATGCTGCCCTCAGACTTTGCGCTGACCGAGTCGCTGCTGGCGAAGACCAATCCTGAGCTGGCGCTCAAGTtggcggcagctgcagccgccGCCGTCGCGGGCAGCAGCCCTGCAGAGCTGGCCAGCAAGCTGGGCTTCGCAGCAGCTGCTAGTGGCGCTGCGTCGGCTGCGGGTCCTCCAACTGCGAACGCCTCCAGCGGACAGCCGCAGATCTACGTCAAGCAGGGCGTCTCCAAGTGCAAGGAGTGCAACATTGTCTTCTGCAAGTACGAGAACTACCTGGCCCACAAGCAGCACTACTGCTCGGCACGCAACCAGGAGCCGAGCGAGGCCGATGCGAAGACAGCAGGCACGCCGCCCAGCGGAGGGGCAGCTGGTGTTGGCGTAGGAGCCGCATCCGCGGCGGAGACAACGCCCGTGGCATATCAACAGCTGATCTGCGCAGCCTGCGGCATCAAGTACACCTCGCTGGACAACCTGCGCGCCCACCAGAACTACTACTGCCCCAAGGGTGGTGCGGCAGCCACAGCCGTGGATGCAGCGGTCCAGCTACCGCTACCCAAGGAGAAATGCGTCAAATGCAAGACGCTGCACGAGCACGGCCAGCCCTGCCAGCCGCCGCCAGCAACGCCCCAGATGCCGACACATTTGAGTCCCTGCCCGGGCGCCGGCAGCGGAGGCGCCTCCTCCAACAGCGTCAACAAATGCCCCGTTTGCGGCGTGGTCAGTCCCACAGCGGCGCTGGCTCGCAAGCACATGGAGATGCATGGCACGGTGAAGGCCTTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGTGGCATGCGCACCCACATACGCACCCACTTTGATAAGAAGACCAGCGATGTGAACGAGGAGCATTACATGACCTGCATCTTCGAGGAGGACGCTGCCGCTCCTCCTGCTGCAAGCCTAGCCCAGGGGCTGAGCCTGGGCCTGGAGCTGCCCTCCGTAGCGGTGGCCGTGGCGGCGCAGGAGCAGctggagcaacagcagcagccgcctcAGCTCTTCAACTGCGACTACTGCAACTACGCCTCCACTTACAAGGGCAATGTGCTGCGTCACATGAAACTACTGCATCCGCACGTGGCAATCAGTTCACCATCTATTTCGCCCGAGTCCCGTGAACTGGACTCCAATCCACACACCATTCCCGAAGTATCCCTGGTTAACGGGGAGCGGGATACTGCTGCCGTGGCCAGCTTCCACATCAAAACAGAGCCACTGGAACACCCCGTTGCGACGCTGAGCCTGGTGCATGAGAACAACAACTCGCCCATTGGCACTCCCCACAGCCATATCAAGGCCGAGCCCCTGGACATGGGCATCGATGTATCACCGCCGGCGCTGCCGCCTCCAGTCTCTAACTCGCCCTTGGGCCCCAGTGCCGCCGAGGCCATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAGACCTTCCTGGCCCACAAGCAGTTCTACTGCAAGAGCAAGCTACACCGACCCGAGGCCAACGATAGCCCCAGTCCCAACCATGTGGGCGCCACTGTGGGCGCCTCAATGCCCCTACAGTCACCCAgcgagctgctgttgctgcagaaGAACAAGGAGAACCTCCAGGAGGCGGCCATTTGA
Protein Sequence: MRRARREAQDRTRLGLGLGREMEMQHGDAVDCSHSKDLGAHELSEEKQQQQLEEQSDEEHGENQTSNASDQPVETDMDQDMIEAQAVQEANEQQQQEKQRETDNSTTPPRSPTPELVPKLERAEQPATPPSGAATPSPPPTPTPMPTTVLPKLRLNALLASDPALKPDAKELNLSDARLLGPPPQLAKPEQSLPDPSSLVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKETDEETPAGDKATTTAGGGASATANSSNSGGGASSEPPAKQARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSLPSLSSLPSLASLTANGVSAAVGAGSLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGAAGTGTGVSVGAGAGKLSGGHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGTATPTPTPMASSNQLPIPALEPDRQPASSGSALEAEAKSSPPEPKRKETGGTRESTPLDLSLRRSPISALLQRQRLVRSAAALLDAEEALLAAGKENMERGGSGGSVTPEQIVCAPSLPSSPSMSPSPKRRAVSPRSSGAGSAASMSPPTLSVGVGMPHLLDSLPPLRSMLPSDFALTESLLAKTNPELALKLAAAAAAAVAGSSPAELASKLGFAAAASGAASAAGPPTANASSGQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEPSEADAKTAGTPPSGGAAGVGVGAASAAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATAVDAAVQLPLPKEKCVKCKTLHEHGQPCQPPPATPQMPTHLSPCPGAGSGGASSNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAPPAASLAQGLSLGLELPSVAVAVAAQEQLEQQQQPPQLFNCDYCNYASTYKGNVLRHMKLLHPHVAISSPSISPESRELDSNPHTIPEVSLVNGERDTAAVASFHIKTEPLEHPVATLSLVHENNNSPIGTPHSHIKAEPLDMGIDVSPPALPPPVSNSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEANDSPSPNHVGATVGASMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558210;
90% Identity: iTF_00805478;
80% Identity: -