Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: ush
Assembly: GCA_037075165.1
Location: JBAMCL010000789.1:958158-967136[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.062 4.2 8.3 0.0 1 20 231 250 231 252 0.89

2 9 0.00036 0.024 15.3 0.8 1 23 307 329 307 329 0.98

3 9 0.064 4.3 8.2 1.0 2 21 374 393 374 394 0.92

4 9 0.062 4.2 8.3 2.9 2 21 779 798 778 799 0.93

5 9 0.012 0.77 10.6 0.0 3 21 847 865 845 866 0.91

6 9 0.0083 0.56 11.0 0.0 2 23 935 956 934 956 0.98

7 9 0.0049 0.33 11.7 1.3 1 23 962 984 962 984 0.99

8 9 0.00089 0.059 14.1 0.8 1 23 1047 1070 1047 1070 0.96

9 9 0.39 26 5.8 0.7 2 20 1180 1198 1179 1200 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.062	4.2	8.3	0.0	1	20	231	250	231	252	0.89
2	9	0.00036	0.024	15.3	0.8	1	23	307	329	307	329	0.98
3	9	0.064	4.3	8.2	1.0	2	21	374	393	374	394	0.92
4	9	0.062	4.2	8.3	2.9	2	21	779	798	778	799	0.93
5	9	0.012	0.77	10.6	0.0	3	21	847	865	845	866	0.91
6	9	0.0083	0.56	11.0	0.0	2	23	935	956	934	956	0.98
7	9	0.0049	0.33	11.7	1.3	1	23	962	984	962	984	0.99
8	9	0.00089	0.059	14.1	0.8	1	23	1047	1070	1047	1070	0.96
9	9	0.39	26	5.8	0.7	2	20	1180	1198	1179	1200	0.91

Sequence Information

Coding Sequence: ATGCATTTTCCAGCCTGTGACATCTACGAGTCGGCTACGTGCGCTAAATTAGTCGCCGGCCTGAACTCTGGGAAGGAGAGGTCGGAGTCCAATTCGGAGTCCAATTCAGAGTCGCAGTCAATCGAGCTTTGTTTGATTCGTCTACACAAATTCTTACAAAACATAGCCTCAGGCATAGATTCCAAAGATTTAGGCGCGCACGAGCTGAGCGaggagaagcagcagcagcagctcgagGAGCAGTCCGACGAAGAGCACGGGGAGAACCAAACTAGCAACGCCTCCGATCAGCCCGTAGAGACGGACATGGATCAGGAGATGATCGAGGCTCAGGCAGCGCAGGAGGccaacgagcagcagcagcaggagaagCAGAGGGAGACCGACAACTCGACAACGCCGCCGCGTAGTCCAACGCCAGAGCTGGTGCCCAAACTGGAGAGAGCTGAGCAGCCGGCCACGCCGCCCTCAGGGTCAGCCACGCCCAGCCCCCCGCCCACGCCCACTACTGTGCTGCCAAAGCTGCGCCTCAATGCGCTACTCGCCTCCGATCCGGCCCTGAAGCCAGACGCCAAGGAACTGAACCTGTCCGATGCACGCCTACTGGGTCCACCCCCGCAGCTGGCCAAGCCCGAGCAAAGCCTACCAGATCCTAGCAGCCTCGTGGAGCCGCTCCTGAAACCGGCGCGCTTCATGTGCCTGCCCTGCAGCATTGCCTTCAGCTCCCCCTCAACGCTGGAGGCGCACCAAGCCTACTACTGCTCCCATCGCAACAAGGAGACCGACGAGGAGACACCCACCGGCGACAAAGCCACAACCACAGCCGGGAGTGGCGCCTCCGCCACAGccaatagcagcaacagcggcagcggtgcCAGCTCGGAGCCACCCGCCAAGCAGGCCCGCACTGGGAAGCAGTACGCCTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTGAACCGGCACATGCGCATGCACCAGACCTCGCCGGCCCCCAGCCTGCCCAGCTTGTCCAGCCTGCCCAGCCTGGCCTCCCTGACGGCCAATGGGGTCTCGGCCGCTATCGGCGCCGGCTCCCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGGTTCAACAACATCAAGACCTACCGCGCCCACAAGCAACACTACTGCAGCTCCCGACGCAGCGATGGCCAGCTGACGCCCAAGCCGGAGGCAGGCGCCGCCGGAACCGGAACTGGCGTCTCAGTGGGAGTTGGAGCGGGCAAGCTAAGTGGCGGCCACAGTCCACAGACGCGCAACAAGACGCCCACGCCGGCAATGGTTGCGGCAGCGgccgccgcagctgctgccgctgccgcctcgCTGCAGGTGGCGCCGCCCCAGCCCTTCCTGGCACTGCCCACCAACCCCATCATCATTGTGCCCTGCTCGCTCATACGAGCAGCCAGCCTGATTCCGGGACCGCTCACCACCTCCACGTCGGGCATTGTTAATCCCGAGTCCACGTGCTTTACGCTCGACAATGGGGCCTTGAAACCGCTGGCCACGGCACTGAATATTAATGCGCTGGCGGgaaatgccacgcccactcccACGCCCATGTCCACCAGCAATCAGCTGCCCATTCCCGCCCTGGAGCCGGATCGTCAGCCCGCAAACAGCGGGAGCGCATTGGAAGCGGAGGCCAAGAGCAGCCCGCCTGAGCCAAAGCGTAAGGAAGCCGGCGGCACTCGAGAATCTACGCCACTGGACTTGTCGCTGCGACGCTCGCCCATTTCAGCGTTGCTGCAACGCCAGCGTCTGGTGCGGTCCGCAGCTGCACTGCTGGAAGCCGAGGAGGCGCTACTGGCAGCGGGTAAGGAGAATGTGGAGAggggcggcagcggcggcagcgtgACGCCAGAGCAAATCGTATGCGCCCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCGCCCAAGCGTCGCGCTGTCAGTCCTCGCAGCTCCGGCGCAGGCAGCGCTGCATCCATGTCGCCCCCGACGCTGAGTGTGGGCGTGGGCATGCCACATCTGCTGGACAGCCTGCCGCCGCTGCGCTCCATGCTGCCCGCGGACTTTGCACTGTCCGAGTCGCTGCTGGCGAAGACCAATCCCGAGCTGGCGCTCAAGTtggcggcagctgcagccgccgccgtcgcAGGCAGCAGCCCTGCAGAGCTGGCCAGCAAGCTGGGCTTCGCAGCAGCTGCTAGTGGAGCTGCGTCAGCTGCGGCTCCTCCAACTGCGAACGCCTCCAGCGGACAACCACAGATCTACGTCAAGCAGGGCGTCTCTAAGTGCAAGGAGTGCAACATTGTCTTCTGCAAGTACGAGAACTACCTGGCCCACAAGCAGCACTACTGCTCGGCACGCAACCAGGAGACGGGCGAGGCCGATGCGAAGACAGCAGGCACGCCGCCCAGCGGAGGGGCAGCTGGCGGTGGCGTAGGAGCCGCATCCGCGGCGGAGACAACGCCCGTGGCATATCAACAGCTGATCTGCGCAGCCTGCGGCATCAAGTACACCTCGCTGGACAACCTACGCGCCCACCAGAACTACTACTGCCCCAAGGGTGGTGCGGCAGCCACAGCCGTGGATGCAGCGGTCCAGCTATCGCTGCCCAAGGAGAAGTGCGTCAAGTGCAAGACGCTGCACGAGCACGGCCAGCCCTGTCAGCCGCCGCCAGCAACGCCTCAGATGCCGACTCATTTGAATCCCTGCCCGGGCGCCGGCAGTGGAGGCGCCTCCTCCAACAGCGTCAACAAATGCCCCGTTTGTGGCGTGGTCAGTCCCACAGCGGCGTTGGCTCGCAAGCACATGGAGATGCATGGCACGGTGAAGGCCTTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACACTGCGTGGCATGCGCACCCACATACGCACCCACTTTGATAAGAAGACCAGCGATGTGAACGAGGAGCATTACATGACCTGCATCTTCGAGGAGGATGCTGCCGCTCCTCCGGCTGCAAGCCTAGCCCAGAGTCTGAGCCTGGGCTTGGAGCTGCCCGCCGTAGCGGTGGCCGTGGCGGCACAGGAGCAGctggagcaacagcagcagccgccacaGCTTTTTAACTGCGACTACTGCAACTACGCCTCCACTTACAAGGGCAATGTGCTGCGTCACATGAAACTGCTGCATCCGCACGTGGCAATCAGTTCACCATCTATTTCGCCCGAGTCACGTGAACTGGACTCCAATCCACACAACATTCCCGAAGTATCCCTGGTTAACGGGGAGCGGGAAACTGCTGCCGTGGCCAGCTTTCACATCAAATCAGAGCCTTTGGAACACCCTGTTGCGACGCTGAGCCTGGTGCATGAGAACAACAACTCGCCCATTGGCACTCCCCACAGCCATATCAAGGCCGAGCCCCTGGACATGGGCATCGATGTATCACCGCCGGCGCTGCCGCCTCCAGTCTCCAACTCGCCCTTGGGCCCCAGTGCCGCCGAGGCCATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAGACCTTCTTGGCCCACAAGCAGTTCTACTGTAAGAGCAAGCTACACCGACCCGAGGCCAACGATAGCCCCAGTCCCAACCATTTGGGTGCCGCTGTGGGCGCCACAATGCCCCTACAGTCGCCCAgcgagctgctgttgctgcagaaGAACAAGGAGAACCTCCAGGAGGCGGCCATTTGA
Protein Sequence: MHFPACDIYESATCAKLVAGLNSGKERSESNSESNSESQSIELCLIRLHKFLQNIASGIDSKDLGAHELSEEKQQQQLEEQSDEEHGENQTSNASDQPVETDMDQEMIEAQAAQEANEQQQQEKQRETDNSTTPPRSPTPELVPKLERAEQPATPPSGSATPSPPPTPTTVLPKLRLNALLASDPALKPDAKELNLSDARLLGPPPQLAKPEQSLPDPSSLVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKETDEETPTGDKATTTAGSGASATANSSNSGSGASSEPPAKQARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSLPSLSSLPSLASLTANGVSAAIGAGSLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGAAGTGTGVSVGVGAGKLSGGHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNATPTPTPMSTSNQLPIPALEPDRQPANSGSALEAEAKSSPPEPKRKEAGGTRESTPLDLSLRRSPISALLQRQRLVRSAAALLEAEEALLAAGKENVERGGSGGSVTPEQIVCAPSLPSSPSMSPSPKRRAVSPRSSGAGSAASMSPPTLSVGVGMPHLLDSLPPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSPAELASKLGFAAAASGAASAAAPPTANASSGQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQETGEADAKTAGTPPSGGAAGGGVGAASAAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATAVDAAVQLSLPKEKCVKCKTLHEHGQPCQPPPATPQMPTHLNPCPGAGSGGASSNSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAPPAASLAQSLSLGLELPAVAVAVAAQEQLEQQQQPPQLFNCDYCNYASTYKGNVLRHMKLLHPHVAISSPSISPESRELDSNPHNIPEVSLVNGERETAAVASFHIKSEPLEHPVATLSLVHENNNSPIGTPHSHIKAEPLDMGIDVSPPALPPPVSNSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEANDSPSPNHLGAAVGATMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558210;
90% Identity: iTF_00803895;
80% Identity: -