Basic Information

Insect: Drosophila melanica
Gene Symbol: -
Assembly: GCA_004143765.1
Location: SCDT01001030.1:19971-23847[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00033 0.033 14.8 0.1 1 23 153 176 153 176 0.96

2 14 0.0011 0.11 13.1 2.9 2 23 225 247 221 247 0.89

3 14 0.0098 0.98 10.2 0.9 1 23 346 369 346 369 0.93

4 14 0.17 17 6.3 5.8 2 23 418 439 417 440 0.95

5 14 0.0026 0.26 12.0 0.5 1 23 503 526 503 526 0.88

6 14 1.6 1.6e+02 3.2 0.1 2 14 545 557 544 569 0.85

7 14 0.00054 0.055 14.1 3.3 2 23 577 599 577 599 0.96

8 14 0.00065 0.065 13.9 0.1 1 23 705 728 705 728 0.95

9 14 3e-05 0.0031 18.1 0.5 1 23 778 801 778 801 0.93

10 14 0.00092 0.092 13.4 2.2 2 23 851 873 850 873 0.97

11 14 0.0015 0.15 12.8 2.0 1 23 958 981 958 981 0.92

12 14 0.041 4.2 8.2 1.5 1 21 1033 1053 1033 1054 0.95

13 14 2.9 3e+02 2.4 0.1 2 23 1099 1123 1098 1123 0.72

14 14 2.8 2.8e+02 2.5 0.2 1 8 1141 1148 1141 1165 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00033	0.033	14.8	0.1	1	23	153	176	153	176	0.96
2	14	0.0011	0.11	13.1	2.9	2	23	225	247	221	247	0.89
3	14	0.0098	0.98	10.2	0.9	1	23	346	369	346	369	0.93
4	14	0.17	17	6.3	5.8	2	23	418	439	417	440	0.95
5	14	0.0026	0.26	12.0	0.5	1	23	503	526	503	526	0.88
6	14	1.6	1.6e+02	3.2	0.1	2	14	545	557	544	569	0.85
7	14	0.00054	0.055	14.1	3.3	2	23	577	599	577	599	0.96
8	14	0.00065	0.065	13.9	0.1	1	23	705	728	705	728	0.95
9	14	3e-05	0.0031	18.1	0.5	1	23	778	801	778	801	0.93
10	14	0.00092	0.092	13.4	2.2	2	23	851	873	850	873	0.97
11	14	0.0015	0.15	12.8	2.0	1	23	958	981	958	981	0.92
12	14	0.041	4.2	8.2	1.5	1	21	1033	1053	1033	1054	0.95
13	14	2.9	3e+02	2.4	0.1	2	23	1099	1123	1098	1123	0.72
14	14	2.8	2.8e+02	2.5	0.2	1	8	1141	1148	1141	1165	0.82

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCAGCCGATTTCGAGGAGGGCGACGATGCCGCAGTAGACACTCATAATAATGGCAAGAATGCATTGGCAGACGAGTTTATGGGCGAAGACGACGATGAGGAGCAGGAGGATGAGGGCAAGCGAAAAGGACACGAGCCCGATGACGATgctatatttgattttgaactGGAGCCAATTGTTAGCATTGCGGAACCAGAACCAGCGCCTAGACCAACTGTCCCATTAGCGCCACCAATGGCAGCGTCGGGACCACCAGCCATACGTCCCCCGCACCGACAATCGCTGCCAGCATCGTTTGGGTCCACAATGATAGTGGGTCGCGGTGTTACCGTTGGGGCACCACCGCCGACACGGCCTACGACATCACAGATCAACGCGACCGATGAAAACGGTGTGCCTATTAATTATGAACTGGgcgttatttatatatgcccTGCCTGCGGCGCCGAGTATAGGCAGCAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAATACTCGCCGGGGTCTTAATTTTGTGGCGATCGATAAGTTGTACCATCGCTGCCTGGAGTGCAATAAACGCATCGCGATGCACAGCCGTGAGAATCTGCTGAAGCACAAGTTTACCCATTTGCCATATCGCTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGGCAGGACCTGATGGTGCATCTGCGTATGGTGCACTGCGATGAGGTCGTGGCCATGATGCGCGGCGGCGATTCCAGTGCTGGACGCAAGACGCGTGTGCGGGAGCCGCGCGTCGAGCCACAGCACGGTCCCTACGGCCCAGTgcatgacgatgacgacggcATCGAGGTTAAGAACGAGGTAATGGAGGCGGACCAAGTTGCCCAGACGGACGAGTCCAGCTTTGGTCTAGACGATGAGCACAGTCAAAGCTCCAGTCAGGCAGCTAAGAAAAAGCGTGGCAatggtgccgctgctggcccGGCGGATATATGCGAAGATTACATACACTACATGTGCCCCGACTGCGGCACCGATTGCGACACGCACGCCCAGTGGAGTCAGCACATTGAGTTCGTTCACGATTATGTGAGCCGGCGCGGTCTCAACTTTCGCTGTGTGGACATGCAGATGCAATGCCTTGAATGCAAAGAGTTTGTCATCCCAAACACAATCAAAACGCTGCGAGCTCACAAGTTTGGCCATTTGTCGCAGCCGGAGTGGATGCGCTGTAAGCTGTGCTATAAGGGCTATACGGAGCATCATGAGCTGGTCACACATCTGCTCAAGCATCATCATTTGGAGACCTTAATGCCCgagcagcaggaggagcagcagccgacGGCCACAGCCAGTGGCAGTGCAGGCGATGAGTGTGAGGATACTAATCAGGGGGACGATGAATCCCTATTGCAGTGGGATGATGTGCCGCGTCGTGGCGGTCGCATTGGCAGCGATGATATATATGAGCCGCATATTGATTACTTGTGTCCGCAGTGTGGCCGGGAGTTCATTGAGAAGAAACACTGGCGCACCCATGTTGTTCAGGTGCACGGCATGAATGATCTGGCCAAGCTGAACTTTGAGGTGATAAACGATCGCCAGCTCAAGTGCACCGAATGCGATAAGATCATCACTAACGCATATGGCATACAGAATGCGCAGCAGCACAGGATTACGCATTTGCCGTACAAGGCGTATGCCAGATGCCGCAAATGCCATAAATCCTATACAGATCGTAAGGGTCTCGTCAAGCATTTGGCCACATACCATCGTATTGGCTTTGAGCCACGCAAACCGGGTGCGGCAGGGAGCGCGGGTGGTGGCGCTGGTCCAGTCCAGAGTTTGGGGATGTCACCAGCTAAAGTGCAGGCGCCGCGCAAACAAATTGTCACCGTGGCCAATGAAACGTATGAGATCATCTACTTGGATGAGGAGCAATCGCCACcgagcaataataatattaacgaGGAGAATGATTTCGGCGAGCAAATGCAAgcggatgatgatgattatgccATAGGCAGCAACCAGCTGCCAACACCtacagctgccgctgcactCCCGTCGCATCCCAATTCGAATCGCTATAAATGCGTCGATTGCGGTTCTCTGTTTGCCACACAGACGGCGCTCAAGACGCACATCAGCGAGGAGCACGACTTTATGGACACGCAATATAGTGCCAAAAAGTTTGACAATGCGGAGCCCACGGAGGAGGCGCCTACAGCCATCACGGTGCCCACGGCAAGTGGTTCTCCTGCAAGGAACAGCGCTGGCGCCTCCACGATTgagcaaaattatatattcctGTGCCCGTCGTGCGGCAAGTCATACAAGACGCAATTCGAGTGGCGGCGCCACATTAACGAGGAGCACAATTTCGATAAGCGGCAATATCTGAATATGCGCCAGCTGGACAAGTATCGCTATCAGTGTACACTGTGCAAGGACATAGTTTGCAATTCGAAGCTGAAAGGACTGCAGGATCATCACTTCCGCCATTTGCCTTACAGGCTATATCTGAAGTGCCTCGTGTGCGGCACCTGCTACAATCACAAGCCGAACATTGCTGCGCATCTGCGCACACGGCACAATATCTATGAGCGCGAGTCAGCTTGGCGCGAGCAGCAGCCGAAGTCGCAGAATGGGTACGAGCAGGTCAAGTATAAGGATCGGGATAGGGACACGCAAGCGGTGTCCTGCTCGACCTCAGCATCGCCCACGCCGGGCAGCAGTCGGACGCTCAAGCCACAGCCGGGAGTGCTGCCCACACGACCGGCTGGCCTAAATACCCTGGAGGACAGCATTTCGTATCATAATGCCGTCGATTTGGACTTTATCACTTACTACTGCCCCAAGTGCAACAAGAACTTTGATTCGCACGCATTCTGGCGTAAACACATCGTGGAACAGCACAACTATAACAGTCGGCAGGGCCTCAATTTCCGGCAGATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGAGTCACGGTCACCCACACCAAGGGTGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGGCATCTGCCCTATCGTTCCTTCAAGTGCTTGACCTGCAACGGTGAATTTGTGCGTAAGCAAATGTTCTTTAAGCATTTGAATCGGGACACCAATCGGTGCGATAACAAACCGCTGAGCGGACAGGACAATGAGGAGGATGCcgtggagcagcagccgccagaCAGAGCAGCTGCAACGCTCGCCAACGAGACAATTGATGGCGCCGCCTATCGTCTAATGTGTCCGCAATGCGGCGATAACTTCACCACCGGCAGCAAAGCTCTGTGGCGCGAGCACATCAATATCTATCACGGCCTGGGTAAGCGTGAAATGCTGCATATGCGAAAGTTGGGCGAGGAGCTGTACCGCTGCACAGACTGTGACGAGCAGCTGCAGACGAACCAGGTGCGCGTCCTCCAGGAGCATCGATTCCGCCATTTGCCCTATGCCGCCTACATACGCTGCCAGCTCTGCGAGCAACAGGCGCCGGACGGACTGGGCCATGGTGCGGTCGCTGCCGGACTGCACAGTATGcgggagctgcagcagcatatATGGGACAAGCATCCCCAAGTGGCCGAGCACGATGGGCAAATGCAAGCGCTGTTCGACGAGGAGGATGAGGAGAATGCGGATTGCCAGCCGTCGGTTGTCAATGAAGCGTCGGACAGTGGGCCATATATGCCCCTGCCGCCGCATTTGCTGGACGATGACGCCGAAGACATGGAGTTCGAGGAGCAGTATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDDAAVDTHNNGKNALADEFMGEDDDEEQEDEGKRKGHEPDDDAIFDFELEPIVSIAEPEPAPRPTVPLAPPMAASGPPAIRPPHRQSLPASFGSTMIVGRGVTVGAPPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDSSAGRKTRVREPRVEPQHGPYGPVHDDDDGIEVKNEVMEADQVAQTDESSFGLDDEHSQSSSQAAKKKRGNGAAAGPADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFGHLSQPEWMRCKLCYKGYTEHHELVTHLLKHHHLETLMPEQQEEQQPTATASGSAGDECEDTNQGDDESLLQWDDVPRRGGRIGSDDIYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRIGFEPRKPGAAGSAGGGAGPVQSLGMSPAKVQAPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIGSNQLPTPTAAAALPSHPNSNRYKCVDCGSLFATQTALKTHISEEHDFMDTQYSAKKFDNAEPTEEAPTAITVPTASGSPARNSAGASTIEQNYIFLCPSCGKSYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESAWREQQPKSQNGYEQVKYKDRDRDTQAVSCSTSASPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSGQDNEEDAVEQQPPDRAAATLANETIDGAAYRLMCPQCGDNFTTGSKALWREHINIYHGLGKREMLHMRKLGEELYRCTDCDEQLQTNQVRVLQEHRFRHLPYAAYIRCQLCEQQAPDGLGHGAVAAGLHSMRELQQHIWDKHPQVAEHDGQMQALFDEEDEENADCQPSVVNEASDSGPYMPLPPHLLDDDAEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00547591; iTF_00589085; iTF_00598431; iTF_00561280; iTF_00567792;
80% Identity: -