Basic Information

Insect: Drosophila micromelanica
Gene Symbol: -
Assembly: GCA_004143905.1
Location: SCDX01000245.1:232137-235992[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00035 0.025 14.8 0.1 1 23 153 176 153 176 0.96

2 14 0.0012 0.086 13.1 2.9 2 23 225 247 221 247 0.89

3 14 0.011 0.74 10.2 0.9 1 23 344 367 344 367 0.93

4 14 1.4 97 3.5 5.2 2 23 416 438 415 439 0.95

5 14 0.0028 0.19 12.0 0.5 1 23 501 524 501 524 0.88

6 14 1.7 1.2e+02 3.2 0.1 2 14 543 555 542 567 0.85

7 14 0.00059 0.041 14.1 3.3 2 23 575 597 575 597 0.96

8 14 0.0007 0.049 13.9 0.1 1 23 699 722 699 722 0.95

9 14 7.1e-05 0.005 17.0 0.3 1 23 772 795 772 795 0.93

10 14 0.00099 0.069 13.4 2.2 2 23 845 867 844 867 0.97

11 14 0.0016 0.11 12.8 2.0 1 23 952 975 952 975 0.92

12 14 0.045 3.1 8.2 1.5 1 21 1027 1047 1027 1048 0.95

13 14 3.8 2.7e+02 2.1 0.1 2 23 1093 1117 1092 1117 0.79

14 14 2.6 1.8e+02 2.6 0.3 1 9 1135 1143 1135 1159 0.76

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00035	0.025	14.8	0.1	1	23	153	176	153	176	0.96
2	14	0.0012	0.086	13.1	2.9	2	23	225	247	221	247	0.89
3	14	0.011	0.74	10.2	0.9	1	23	344	367	344	367	0.93
4	14	1.4	97	3.5	5.2	2	23	416	438	415	439	0.95
5	14	0.0028	0.19	12.0	0.5	1	23	501	524	501	524	0.88
6	14	1.7	1.2e+02	3.2	0.1	2	14	543	555	542	567	0.85
7	14	0.00059	0.041	14.1	3.3	2	23	575	597	575	597	0.96
8	14	0.0007	0.049	13.9	0.1	1	23	699	722	699	722	0.95
9	14	7.1e-05	0.005	17.0	0.3	1	23	772	795	772	795	0.93
10	14	0.00099	0.069	13.4	2.2	2	23	845	867	844	867	0.97
11	14	0.0016	0.11	12.8	2.0	1	23	952	975	952	975	0.92
12	14	0.045	3.1	8.2	1.5	1	21	1027	1047	1027	1048	0.95
13	14	3.8	2.7e+02	2.1	0.1	2	23	1093	1117	1092	1117	0.79
14	14	2.6	1.8e+02	2.6	0.3	1	9	1135	1143	1135	1159	0.76

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCAGCCGATTTTGAGGAGGGCGACGATGCTGCAGTAGACACTCATAATAATGGCAACAATGCTCTGGCAGACGAGTTTATGGGCGAAGAAGACGATGAGGAGCAGGAGGATGAGGGCAAGCGAAAAGGACACGAGCCCGATGATGATGccatatttgattttgaactGGAGCCAATTGTTAGTATTGCGGAACCAGAACCAGCGCCCAGACCAACTGTCCCATTAGCGCCACCAATGGCAGCGTCGGGACCACCAGCCATACGCCCCCCGCACCGACAATCACTGCCAGCATCGTTTGGGTCCACAATGATAGTGGGTCGCGGTGTTACTGTTGGGGCACCACCGCCCACACGGCCAACGACATCACAGATCAACGCCACCGATGAGAACGGTGTGCCCATTAATTATGAACTGGGCGTCATCTATATATGCCCCGCCTGCGGCGCCGAGTATAGGCAGCAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAATACACGCCGGGGTCTTAATTTTGTGGCGATCGATAAGTTGTACCATCGATGCCTCGAGTGCAATAAACGCATCGCGATGCACAGCCGTGAGAATCTGCTGAAGCACAAGTTCACCCATTTGCCATATCGCTGCACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGGCAGGACCTAATGGTGCATCTGCGTATGGTACATTGCGACGAGGTCGTGGCCATGATGCGCGGCGGCGATTCCAGTGCTGGACGCAAGACGCGTGTCCGCGAGCCGCGCGTCGAGCCACAGCACGGACCCTATGGCCCGGTgcatgacgatgacgacggcATCGAGGTGAAGAACGAGGTAATGGAGGCGGAGCAAGTTCCCCAGGCGGACGAGTCCAGTTTTGGTCTGGACGATGAGCAAAGTCACAGCTCCAGTCAGGCAGCCAAGAAGAAACAGCGTGCCGCTACTGGTCCGGCGGATATATGCGAAGATTATATACACTACATGTGCCCTGACTGCGGCACCGATTGCGACACACACGCCCAGTGGAGCCAGCACATTGAGTTCGTTCACGATTATGTCAGCCGGCGCGGTCTCAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAAACGCTGCGTGCGCACAAGTTTGGCCATTTGTCGCAGCCGGAGTGGATGCGGTGTAAGCTATGCTATCAGGGCTATACGGAGCATCATGAGCTGGTCACACATCTGCTCAAGCAGCATCATTTGGAGACCTTAATGCcggagcagcaggaggagcagcagcccaCGGCCACAGCCACTGGCAGTGGAGGCGATGAGTGTGAGGATATTAATCAGGGCGACGATGAATCCCTATTGCAGTGGGATGATGTGCCGTGTCGTGGCGGTCGCATTGGCAGCGATGATATATATGAGCCGCATATTGATTACTTGTGTCCGCAGTGCGGCCGTGAGTTCATTGAGAAGAAACACTGGCGCACCCATGTTGTCCAGGTGCACGGCATGAATGATCTGGCCAAGCTGAACTTTGAGGTGATCAACGATCGCCAGCTCAAGTGCACCGAATGCGATAAGATCATCACGAACGCCTATGGCATACAGAATGCGCAGCAGCACAGGATTACGCATTTGCCGTACAAGGCGTATGCGAGATGCCGCAAATGCCATAAATCCTATACAGATCGCAAGGGTCTCGTCAAGCATTTGGCCACATACCATCGCGTTGGCTTTGAGCCGCGCAAACCGGGCGTGGGCGGTGGCACAGGACCAGTCCAGAGCCTGGGGATGTCACCAGCTAAAGCGCAGGCGCCACGCAAACAAATTGTCACCGTGGCGAACGAAACGTATGAGATCATTTACTTGGACGAGGAGCAATCGCCACCGagtaataataacattaaCGAGGAGAATGATTTTGGCGAGCAAATGCAAgcggatgatgatgattatgccATAGGCAGCAACCAGCTGCCAACACAAACAGCTGCCACTGCTGTTCCATCGCATCCCAATTCGAATCGCTATAAATGCGTCGATTGCGGCTCTCTGTTTGCCACACAGACGGCGCTCAAGACGCACATCAGCGAGGAGCACGACTTTATGGACACGCAATATAGTGCCAAAAAGTTTGATAATGCGGAGCCCACGGAGGAGGCACCTACCGCCATGTCAGTGCCCGCGATAAGCGGTTCTCCTGCAAAGAACAGCGCCGGCGCCTCCACGATCgagcaaaattatatattcctGTGCCCGTCGTGCGGCAAGGCATACAAGACGCAGTTTGAGTGGCGGCGCCACATCAACGAGGAGCATAATTTCGATAAGCGGCAATATCTGAATATGCGCCAGCTGGACAAGTATCGCTATCAGTGCACGCTGTGCAAGGATATCGTGTGCAACTCGAAGCTGAAAGGACTGCAGGATCATCATTTCCGCCATTTGCCTTACAGGCTATATCTAAAGTGCCTCGTCTGCGGCACCTGCTACAATCACAAGCCCAACATTGCGGCGCATCTGCGCACGAGGCACAATATTTATGAGCGCGAATCAGCTTGGCGCGAACAGCAGACGAAGTCGCAGAATGGGTACGAGCAGGTCAAGTACAAGGATCGGGATAGGGACACGCAACCGGTGACTTGCTCAACCTCAGCATCGCCCACGCCGGGCAGCAGTCGGACGCTCAAGCCACAGCCGGGCGTGCTGCCCACACGACCGGCTGGCCTTAATACCCTGGAGGACAGCATCTCGTATCACAATGCCGTCGATTTGGACTTTATCACCTACTATTGCCCCAAGTGCAACAAGAACTTTGATTCGCACGCCTTCTGGCGTAAACACATCGTGGAACAGCACAACTATAACAGTCGGCAGGGCCTGAACTTCCGGCAGATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGAGTCACGGTCACCCACACCAAGGGTGCCATTGGCCAGCTACAATCGCACAAGTTCCGGCATCTGCCCTATCGCTCCTTCAAGTGTTTGACCTGCAACGGTGAATTCGTGCGCAAGCAAATGTTCTTCAAACATTTGAATCGGGACACCAACCGCTGCGACAACAAACCGCTGAGCGGACAGGATAATGAGGACGATGCCgccgagcagcagccgccAGACAAAGCAGCTGCAACGCCCGCCAACGAGACAATCGATGGCGCCGCCTATCGTCTGATGTGCCCGCAATGCGGGGATTACTTCACCACCGGCAGCAAAGCTTTGTGGCGCGAGCACATCAATATCTATCACGGCCTGGGCAAGCGGGAAATGCTGCACATGCGCAAGCTGGGCGAGGAGCTCTATCGCTGCACAGACTGTGACGAGCAGCTGCAGACGAAGCAGGTGCGTGTCCTCCAGGAGCATCGATTCCGCCATTTGCCCTATGCCGCTTACATACGCTGCCAGCTGTGCGAACAGCAGCCGCCAGACGGACTGGGCCATGGTGCGGTCGCTGCCGGACTGCACAGCATGcgggagctgcagcagcatatACGCGACAAGCATCCCCATGTGGCCGAGCAAGATGGGCAAATGCAAGCGCTGTTCGACGAGGAGGATGACGAGGATGCGGAGTGCCAGCCGGCGGTTACCAATGAGGCGTCGGACAGTGGGCCATATATGCCACTGCCGCCGCATTTGCTGGAAGATGATGCCGAAGACATGGAGTTCGAGGAGCAGTATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDDAAVDTHNNGNNALADEFMGEEDDEEQEDEGKRKGHEPDDDAIFDFELEPIVSIAEPEPAPRPTVPLAPPMAASGPPAIRPPHRQSLPASFGSTMIVGRGVTVGAPPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDSSAGRKTRVREPRVEPQHGPYGPVHDDDDGIEVKNEVMEAEQVPQADESSFGLDDEQSHSSSQAAKKKQRAATGPADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFGHLSQPEWMRCKLCYQGYTEHHELVTHLLKQHHLETLMPEQQEEQQPTATATGSGGDECEDINQGDDESLLQWDDVPCRGGRIGSDDIYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGFEPRKPGVGGGTGPVQSLGMSPAKAQAPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIGSNQLPTQTAATAVPSHPNSNRYKCVDCGSLFATQTALKTHISEEHDFMDTQYSAKKFDNAEPTEEAPTAMSVPAISGSPAKNSAGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESAWREQQTKSQNGYEQVKYKDRDRDTQPVTCSTSASPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSGQDNEDDAAEQQPPDKAAATPANETIDGAAYRLMCPQCGDYFTTGSKALWREHINIYHGLGKREMLHMRKLGEELYRCTDCDEQLQTKQVRVLQEHRFRHLPYAAYIRCQLCEQQPPDGLGHGAVAAGLHSMRELQQHIRDKHPHVAEQDGQMQALFDEEDDEDAECQPAVTNEASDSGPYMPLPPHLLEDDAEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496137;
90% Identity: iTF_00541962;
80% Identity: -