Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: -
Assembly: GCA_004149445.1
Location: SCDR01001058.1:48492-52371[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00036 0.043 14.8 0.1 1 23 153 176 153 176 0.96

2 14 0.0012 0.15 13.1 2.9 2 23 225 247 221 247 0.89

3 14 0.011 1.3 10.2 0.9 1 23 347 370 347 370 0.93

4 14 1.4 1.7e+02 3.5 5.2 2 23 419 441 418 442 0.95

5 14 0.0028 0.34 12.0 0.5 1 23 504 527 504 527 0.88

6 14 1.7 2.1e+02 3.2 0.1 2 14 546 558 545 570 0.85

7 14 0.0006 0.072 14.1 3.3 2 23 578 600 578 600 0.96

8 14 0.00071 0.085 13.9 0.1 1 23 706 729 706 729 0.95

9 14 7.3e-05 0.0087 17.0 0.3 1 23 779 802 779 802 0.93

10 14 0.001 0.12 13.4 2.2 2 23 852 874 851 874 0.97

11 14 0.0016 0.19 12.8 2.0 1 23 959 982 959 982 0.92

12 14 0.046 5.5 8.2 1.5 1 21 1034 1054 1034 1055 0.95

13 14 3.9 4.7e+02 2.1 0.1 2 23 1100 1124 1099 1124 0.79

14 14 2.7 3.2e+02 2.6 0.3 1 9 1142 1150 1142 1166 0.76

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00036	0.043	14.8	0.1	1	23	153	176	153	176	0.96
2	14	0.0012	0.15	13.1	2.9	2	23	225	247	221	247	0.89
3	14	0.011	1.3	10.2	0.9	1	23	347	370	347	370	0.93
4	14	1.4	1.7e+02	3.5	5.2	2	23	419	441	418	442	0.95
5	14	0.0028	0.34	12.0	0.5	1	23	504	527	504	527	0.88
6	14	1.7	2.1e+02	3.2	0.1	2	14	546	558	545	570	0.85
7	14	0.0006	0.072	14.1	3.3	2	23	578	600	578	600	0.96
8	14	0.00071	0.085	13.9	0.1	1	23	706	729	706	729	0.95
9	14	7.3e-05	0.0087	17.0	0.3	1	23	779	802	779	802	0.93
10	14	0.001	0.12	13.4	2.2	2	23	852	874	851	874	0.97
11	14	0.0016	0.19	12.8	2.0	1	23	959	982	959	982	0.92
12	14	0.046	5.5	8.2	1.5	1	21	1034	1054	1034	1055	0.95
13	14	3.9	4.7e+02	2.1	0.1	2	23	1100	1124	1099	1124	0.79
14	14	2.7	3.2e+02	2.6	0.3	1	9	1142	1150	1142	1166	0.76

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCAGCCGATTTCGAGGAGGGCGACGACGCTGCAGTAGACACTCATAATAATGGCAATAAATCTTCGGCAGACGAGTTTATTGGCGAAGAGGACGATGAGGAGCAGGAGGATGAGGGCAAGCGAAAAGCACACGAGCCCGACGACGATgccatatttgattttgaactGGAGCCAATAGTTAGCATTGCGGAACCAGAACCAGCGCCCAGACCAACTGTCCCATTAGCGCCACCAATGGCAGCGTCGGGACCACCAGCCATACGCCTCCCGCACCGACAATCGCTGCCAGCATCGTTTGGGTCCACAATGATAGTGGGTCGCGGTGTTACTGTAGGGGCACCACCGCCCACACGACCAACGACATCACAGATCAACGCCACCGATGAGAACGGTGTGCCCATTAATTATGAACTCGGCGTCATCTATATATGCCCCGCCTGCGGCGCCGAGTATAGGCAGCAGGATATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAATACGCGCCGGGGTCTTAATTTTGTGGCGATCGATAAGTTGTACCATCGTTGCCTGGAGTGCAATAAACGCATCGCGATGCACAGCCGTGAGAATCTGCTGAAGCACAAGTTCACCCATTTGCCATATCGCTGCACCAAGTGCTACATCTGCAAGCGTGAGTACAAGTACAGGCAGGACCTGATGGTGCATCTGCGTATGGTGCACTGCGACGAGGTCGTGGCCATGATGCGCGGCGGCGATTCCAGTGCAGGACGCAAGACGCGAGTGCGCGAGCCGCGCGTCGAGCCACAGCACGGTCCCTACGGTCCGGTgcatgacgatgacgacggcATCGAGGTAAAGAACGAGGTTATGGAGGCGGAGCAAGTTGCCCAGACGGACGAGTCCAGCTTTGGTCTGGACGACGAGCAGAGTCTCAACTCCAGTCAGACAgccaagaagaagcagcggGGCAATGGTGCCGTTGCTGGCCCGGCGGATATTTGCGAAGATTATATACACTACATGTGTCCCGACTGCGGCACCGATTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAGTTCGTTCACGATTATGTCAGCCGGCGCGGTCTCAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCAAACACAATCAAAACGCTGCGTGCGCACAAGTTTGGCCATTTGTCGCAGCCGGAGTGGATGCGGTGTAAGCTGTGCTATCAGGGCTATACGGAGCATCATGAGCTGGTCACACATCTGCTCAAGCAGCATCATTTGGAGACCCTAATGCCagagcagcaggaggagcagcagcctACGGCCACAGCCAGTGGCAGTGTAGGCGATGAGTGTGAGGATAGTAATCAGGTCGACGATGAATCGCTATTGCAGTGGGATGATGTGCCGCGTCGTGGCGGCCGCATTGGCAGCGACGATATATATGAGCCACATATTGATTACTTGTGTCCGCAATGCGGCCGGGAGTTCATTGAGAAGAAACACTGGCGCACCCATGTTGTCCAGGTGCACGGCATGAATGATCTGGCCAAGCTGAACTTTGAGGTGATCAACGATCGCCAGCTCAAGTGCACCGAATGCGATAAGATCATCACAAACGCCTATGGCATACAGAATGCGCAGCAGCACAGGATTACGCATTTGCCGTACAAGGCGTATGCGAGATGCCGCAAATGCCATAAATCCTATACAGATCGCAAGGGTCTGGTCAAGCATTTGGCCACATACCATCGCATTGGCTTTGAGCCGCGCAAACCGGGCGCGGCAGGGGGCGCGGGCGGTGCTACAGGTCCAGTCCAGAGTCTGGGGATGTCACCGGCCAAAGCGCAGGCGCCGCGCAAACAAATTGTCACCGTGGCCAACGAAACGTATGAGATTATCTACTTGGATGAGGAGCAATCGCCACCtagtaataataacattaacgAAGAGAATGATTTTGGCGAGCAAATGCAAgcggatgatgatgattatgccATAGGCAGCAACCAGCTGCCAACACCtacagctgccgctgcacaTCCATCCCATTCCAATACGAATCGCTATAAATGCGTCGATTGCGGCTCTCTGTTTGCCACACAGACAGCGCTCAAGACGCACATCAGCGAGGAACACGACTTTATGGATACGCAATATAGTGCCAAAAAGTTTGACAATGCGGAGCCCACAGAGGAGACACCTACCGCCTTGACAGTACCCATGGCAAGTGGTTCGCCTGCAAAGAACAGCGCCGGCGCCTCCACGATCgagcaaaattatatattcctGTGCCCGTCGTGCGGTAAGGCATACAAGACGCAGTTCGAGTGGCGGCGCCACATCAACGAGGAGCACAATTTCGATAAGCGGCAGTATCTGAATATGCGCCAGCTGGACAAGTATCGCTATCAGTGCACACTGTGCAAGGACATCGTGTGCAACTCGAAGCTGAAAGGACTGCAGGATCATCATTTCCGCCATTTGCCTTACAGGCTATATCTGAAGTGCCTCGTGTGCGGCACCTGCTACAATCACAAGCCCAACATTGCGGCCCATCTGCGCACACGGCATAATATCTACGAGCGCGAGTCAGCTTGGCGCGAACAGCAGCCCAAGTCGCAGAATGGTTACGAGCAGGTCAAGTACAAGGATCGGGATAGGGACACGCAAGCGGTGTCCTGCTCGAGCTCAGCATCGCCCACGCCGGGCAGCAGTCGGACCCTCAAGCCACAGCCGGGCGTGCTGCCCACACGGCCGGCCGGCCTAAATACCCTGGAGGACAGCATCTCGTATCATAATGCCGTCGATTTGGACTTTATCACCTACTATTGCCCCAAGTGCAACAAGAACTTTGATTCGCACGCCTTCTGGCGTAAACACATCGTGGAACAGCACAACTATAACAGTCGGCAGGGCCTGAATTTCCGGCAGATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGAGTGACGGTCACCCACACCAAGGGTGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGGCATCTGCCCTATCGCTCCTTCAAGTGTTTGACCTGCAATGGTGAATTTGTGCGCAAGCAAATGTTCTTCAAGCATTTGAATCGGGACACCAATCGCTGCGATAACAAACCGCTGAGCGGACAGGACAATGAGGAGGATGCCGTGGAGCAACAGCCGTCAGACAGAGCAGCTGCAACGCCCGCCAACGAGACAATCGATGGCGCCACCTACCGTCTAATGTGCCCGCAGTGCGGCGATTACTTCACCACCGGCAGCAAAGCTTTGTGGCGCGAGCATATCAATATCTATCACGGGTTGGGCAAGCGGGAAATGCTGCACATGCGCAAGCTGGGCGAGGAGCTATATCGCTGCACAGACTGTGACGAGCAGCTGCAGACGAAGCAGGTGCGCGTCCTCCAGGAGCATCGATTCCGCCATTTGCCCTATGCCGCCTACATACGCTGCCAGCTGtgcgagcagcagccgccggtTGGACTGAGCCATGGTGCGGTCGCTGCCGGACTGCACAGTATGCGGGATCTGCAGCAGCATATACGCGACAAGCATCCCCATGTGGCCGAGCACGATGAGCAAATGCAAGCGCTGTTTGacgaggaggatgaggaggatGCGGAGTGCCATCCGGCGGTTAACAATGAGGCGTCGGACAGTGGGCCATAtatgccgctgccgccgcattTGCTGGACGATGACGCCGAAGACATGGAGTTCGAGGAGCAGTATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDDAAVDTHNNGNKSSADEFIGEEDDEEQEDEGKRKAHEPDDDAIFDFELEPIVSIAEPEPAPRPTVPLAPPMAASGPPAIRLPHRQSLPASFGSTMIVGRGVTVGAPPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDSSAGRKTRVREPRVEPQHGPYGPVHDDDDGIEVKNEVMEAEQVAQTDESSFGLDDEQSLNSSQTAKKKQRGNGAVAGPADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFGHLSQPEWMRCKLCYQGYTEHHELVTHLLKQHHLETLMPEQQEEQQPTATASGSVGDECEDSNQVDDESLLQWDDVPRRGGRIGSDDIYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRIGFEPRKPGAAGGAGGATGPVQSLGMSPAKAQAPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIGSNQLPTPTAAAAHPSHSNTNRYKCVDCGSLFATQTALKTHISEEHDFMDTQYSAKKFDNAEPTEETPTALTVPMASGSPAKNSAGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESAWREQQPKSQNGYEQVKYKDRDRDTQAVSCSSSASPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSGQDNEEDAVEQQPSDRAAATPANETIDGATYRLMCPQCGDYFTTGSKALWREHINIYHGLGKREMLHMRKLGEELYRCTDCDEQLQTKQVRVLQEHRFRHLPYAAYIRCQLCEQQPPVGLSHGAVAAGLHSMRDLQQHIRDKHPHVAEHDEQMQALFDEEDEEDAECHPAVNNEASDSGPYMPLPPHLLDDDAEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00541962;
80% Identity: -