Basic Information

Insect: Drosophila robusta
Gene Symbol: -
Assembly: GCA_004143805.1
Location: SCDV01002458.1:96-3957[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00035 0.044 14.8 0.1 1 23 155 178 155 178 0.96

2 14 0.0012 0.15 13.1 2.9 2 23 227 249 223 249 0.89

3 14 0.01 1.3 10.2 0.9 1 23 349 372 349 372 0.93

4 14 1.4 1.7e+02 3.5 5.2 2 23 421 443 420 444 0.95

5 14 0.0036 0.45 11.7 0.4 1 23 504 527 504 527 0.88

6 14 1.7 2.1e+02 3.2 0.1 2 14 546 558 545 570 0.85

7 14 0.00058 0.073 14.1 3.3 2 23 578 600 578 600 0.96

8 14 0.00067 0.084 14.0 0.1 1 23 702 725 702 725 0.95

9 14 7.1e-05 0.0089 17.0 0.3 1 23 773 796 773 796 0.93

10 14 0.00098 0.12 13.4 2.2 2 23 846 868 845 868 0.97

11 14 0.0016 0.2 12.8 2.0 1 23 953 976 953 976 0.92

12 14 0.12 15 6.9 1.5 1 21 1028 1048 1028 1049 0.95

13 14 3.3 4.2e+02 2.3 0.1 2 23 1094 1118 1093 1118 0.75

14 14 7.4 9.3e+02 1.2 0.4 1 8 1136 1143 1136 1160 0.70

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00035	0.044	14.8	0.1	1	23	155	178	155	178	0.96
2	14	0.0012	0.15	13.1	2.9	2	23	227	249	223	249	0.89
3	14	0.01	1.3	10.2	0.9	1	23	349	372	349	372	0.93
4	14	1.4	1.7e+02	3.5	5.2	2	23	421	443	420	444	0.95
5	14	0.0036	0.45	11.7	0.4	1	23	504	527	504	527	0.88
6	14	1.7	2.1e+02	3.2	0.1	2	14	546	558	545	570	0.85
7	14	0.00058	0.073	14.1	3.3	2	23	578	600	578	600	0.96
8	14	0.00067	0.084	14.0	0.1	1	23	702	725	702	725	0.95
9	14	7.1e-05	0.0089	17.0	0.3	1	23	773	796	773	796	0.93
10	14	0.00098	0.12	13.4	2.2	2	23	846	868	845	868	0.97
11	14	0.0016	0.2	12.8	2.0	1	23	953	976	953	976	0.92
12	14	0.12	15	6.9	1.5	1	21	1028	1048	1028	1049	0.95
13	14	3.3	4.2e+02	2.3	0.1	2	23	1094	1118	1093	1118	0.75
14	14	7.4	9.3e+02	1.2	0.4	1	8	1136	1143	1136	1160	0.70

Sequence Information

Coding Sequence: ATGGAAGGTATGGACTTGTGGACGTCTATGTTTTCAACCGATTTCGAGGAGGCCGATGACGCTGCAGTAGACACtcacggcaacggcagcacaGCGCTGGCAGACGAGTTTATGGCCGAAGAGGAGGATGAGGAGCAGGAGGATGAGGACAAGCGAAAAGGACACGAGCCCGATGACGATGccatatttgattttgaactTGAGCCAATTGTTAGCATTGCGGAACCAGAACCGGAACCAGCGCCCAGACCAAGTGCCCCATTGGCGCCACCAATGGCGACGTCGGGTCCACCAGCTATACGCCCCCCGCACCGCCAGTCGCTGCCATCATCGTTCGGCTCCACAATGATGGTGGCTCGTGGTGTTGCCGTTGGGGCACCACCACCCGCCCGGCCAACAACATCACAGATCAATGCCACCGATGAGAACGGTGTACCTATTAACTATGAATTGGGCGTCATCTATATATGCCCTGCTTGCGGCGCCGAGTATCGGCAGCAAGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAATACACGCCGTGGCCTCAATTTTGTGGCCATCGATAAGCTGTACCATCGCTGTCTGGAGTGCAACAAACGCATCGCGATGCACAGCCGGGAGAATCTGCTGAAGCACAAGTTCACCCATTTGCCATATCGGTGTACCAAGTGCTACATCTGCAAGCGCGAGTACAAGTACAGGCAGGACCTGATGGTGCATCTGCGCATGGTGCACTGCGATGAGGTGGTGGCCATGATGCGCGGCGGCGACTCCAGTGCTGGACGCAAGACGCGTGTGCGTGAGCCGCGCGTCGAGCAACAACACGGTCCGTACGGCCCGGTgcatgacgacgacgacggcatCGAGGTGAAGAACGAGCTAATGGAGCCGGAGCACGTTGGCCAGACGGACGAGTCCAACTTTGGCCTGGACGATGAGCAGAGTCGCAGCTCCAGTCAGGCAgccaagaagaagcagcgtggcaatggtgctgctgctgctccggcggATATATGCGAGGATTATATACACTACATGTGCCCCGACTGCGGCACCGATTGCGACACGCACGCCCAGTGGAGCCAGCACATTGAGTTCGTGCACGACTATGTCAGCCGGCGCGGTCTCAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTCGAATGCAAGGAGTTTGTCATCCCGAATACAATCAAGACGCTGCGTGCGCACAAGTTTGGCCATTTGACGCAGCCGGAGTGGATGCGCTGCAAGCTGTGCTATCAGGGCTATACGGAGCATCATGAGCTGGTCACGCATCTGCTCAAGCAACATCATTTGGAGACCCTAATGCCCGaccagcaggaggagcagcccACGGCTAGCGCCAGTGCCAGCGGGGGCGATGACTGTGAGGATAATCAGGGCGACGATGAATCCCTCTTGCAGTGGGATGATGTGCCGCGTCGTGGTGGTCGCATCGGCAGCGATGATATATACGAGCCGCATATTGATTACTTGTGCCCGCTGTGCGGCAGGGAGTTTATTGAGAAGAAACACTGGCGCACCCATGTTGTCCAGGTGCACGGCATGAACGATCTGGCCAAGTTAAATTTTGAGGTGATCAACGATCGCCAGCTGAAGTGCACCGAATGCGATAAGATCATCACGAACGCCTACGGTATACAGAATGCGCAGCAGCACAGGATTACGCATTTGCCTTACAAGGCGTATGCGAGATGCCGCAAATGCCATAAATCCTATACGGATCGCAAGGGTTTGGTCAAGCATTTGGCCACATACCATCGCGTTGGCTATGAGCCGCGCAAAGCGGGCGCGGTCGGAGGCGCAGGTTCCGCCCAGAGTCTGGGCATGCCGCCAGCCAAGGCGCAGGCGCCGCGCAAACAAATTGTCACCGTGGCCAACGAAACTTATGAGATTATCTACTTGGACGAGGAGCAATCGCCGCCgagcaacaataatattaacgAGGAGAATGATTTCGGTGAGCAGATGCAAGCGGATGACGATGATTATGCCATAGGCAGCAgccagctgccagcagcgccagccggTGTTGCACTCCAATCCCATCCCAATTCGAATCGCTATAAATGCGTGGATTGCGGCTCTCTGTTTGCCACACAGGCGGCGCTCAAGACGCACATCAGCGAGGAACACGACTTTATGGACACGCAATATAGTGCCAAAAAGTTTGACAATGCAGAGCCGACGGAGGAGGCGGCCGTGACAGTGGCCGCGGCAACCATGACGCCGGCGAAGAACAGCGCCGGCGCGTCCACCATcgaacaaaattatatattcctGTGCCCGTCGTGCGGCAAGGCATACAAGACGCAGTTCGAGTGGCGGCGTCACATCAACGAGGAGCACAATTTCGATAAGCGGCAGTATTTGAATATGCGCCAGCTGGACAAGTATCGCTATCAGTGCACACTCTGCAAGGACATCGTGTGCAACTCTAAGCTGAAAGGCCTGCAGGATCATCATTTTCGCCATTTGCCTTACAGGCTATATCTGAAGTGCCTCGTCTGCGGCACCTGCTACAATCACAAGCCCAACATTGCGGCGCATCTGCGCACACGGCACAACATCTATGAGCGCGAGTCATCTTGGCGCGAACAGCAGCCCAAGCCGCAGAATGGCTACGAGCAGGTCAAGTACAAGGAACGGGAGAGGGACACACAGGCGGTGACCTGCGCGAGCTCAGCCTCGCCCACGCCGGGCAGCAGTCGGACGCTCAAGCCGCAGCCGGGCGTGCTGCCCACACGGCCGGCGGGCTTGAACACACTGGAGGACAGCATCTCGTATCATAATGCCGTTGATCTGGACTTTATCACCTACTATTGCCCCAAGTGCAACAAGAACTTTGATTCGCACGCCTTCTGGCGCAAGCACATCGTCGAGCAGCACAACTATAACAGTCGGCAGGGCCTGAATTTTCGCCAGATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGCGTCACGGTCACCCACACCAAGGGCGCCATTGGGCAGCTGCAGTCGCACAAGTTCCGGCATCTGCCATATCGTTCCTTCAAGTGCTTGACCTGCAGCGGCGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCATTTGAATCGGGACACCAATCGCTGCGATAACAAACCGCTGACCGGACAGGACAACGAGGAGGATGCCGTGGATCCGCAGCCGCCAGAGAGAGCGGCTGCTACGCCCGCCAACGAAACCGTCGACGGCGCCGCCTATCGTCTGATGTGCCCGCAATGCGGCGATGGCTTCACCACCGGCAGCAAGGCCCTGTGGCGCGAGCACATCAATATCTACCATGGGCTGGGCAAGCGCGAAATGCTGCACATGCGCAAGCTGGGCGAGGAGCTCTATCGCTGCACAGACtgcgaggagcagctgcagacgAAGCAAGTGCGCGTCCTGCAGCAGCATCGATTCCGCCATTTGCCCTACGCCGCCTACATACGCTGCCAGCTGtgcgagcagcagccgccggaCGGACTGGGCCATGGTGCGGCCGCTGCCGGGCTGCACAGCATGCGGGAGCTGCAACAGCATATACGCGACGAGCATCCCCATGTGGCTGCCCATGATGGGCAAATGCAATCGCTGttcgaggaggaggaggaggatgaggatgaggagaGCCAGCCGACGGTTAGCAATGAGGCGTCAGACAGTGGGCCGTATatgccgttgccgccgcatCTGCTGGACGACGACGTCGAAGACATGGAGTTCGAGGAGCAGTATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSTDFEEADDAAVDTHGNGSTALADEFMAEEEDEEQEDEDKRKGHEPDDDAIFDFELEPIVSIAEPEPEPAPRPSAPLAPPMATSGPPAIRPPHRQSLPSSFGSTMMVARGVAVGAPPPARPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDSSAGRKTRVREPRVEQQHGPYGPVHDDDDGIEVKNELMEPEHVGQTDESNFGLDDEQSRSSSQAAKKKQRGNGAAAAPADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKEFVIPNTIKTLRAHKFGHLTQPEWMRCKLCYQGYTEHHELVTHLLKQHHLETLMPDQQEEQPTASASASGGDDCEDNQGDDESLLQWDDVPRRGGRIGSDDIYEPHIDYLCPLCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKAGAVGGAGSAQSLGMPPAKAQAPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIGSSQLPAAPAGVALQSHPNSNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEPTEEAAVTVAAATMTPAKNSAGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESSWREQQPKPQNGYEQVKYKERERDTQAVTCASSASPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPLTGQDNEEDAVDPQPPERAAATPANETVDGAAYRLMCPQCGDGFTTGSKALWREHINIYHGLGKREMLHMRKLGEELYRCTDCEEQLQTKQVRVLQQHRFRHLPYAAYIRCQLCEQQPPDGLGHGAAAAGLHSMRELQQHIRDEHPHVAAHDGQMQSLFEEEEEDEDEESQPTVSNEASDSGPYMPLPPHLLDDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00541962;
80% Identity: -