Basic Information

Insect: Drosophila leonis
Gene Symbol: BCL11A
Assembly: GCA_035045365.1
Location: JAWNPC010000953.1:6927438-6945542[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.054 4.1 8.3 2.5 1 23 282 305 282 305 0.95

2 6 2.7e-06 0.0002 21.8 1.0 1 23 764 786 764 786 0.97

3 6 0.013 0.95 10.3 4.7 1 23 792 814 792 814 0.99

4 6 1.2e-06 8.8e-05 22.9 3.2 2 23 1084 1105 1083 1105 0.97

5 6 1.5e-05 0.0012 19.4 3.3 1 23 1111 1133 1111 1133 0.99

6 6 2.8e-05 0.0021 18.6 0.4 1 22 1141 1162 1141 1162 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.054	4.1	8.3	2.5	1	23	282	305	282	305	0.95
2	6	2.7e-06	0.0002	21.8	1.0	1	23	764	786	764	786	0.97
3	6	0.013	0.95	10.3	4.7	1	23	792	814	792	814	0.99
4	6	1.2e-06	8.8e-05	22.9	3.2	2	23	1084	1105	1083	1105	0.97
5	6	1.5e-05	0.0012	19.4	3.3	1	23	1111	1133	1111	1133	0.99
6	6	2.8e-05	0.0021	18.6	0.4	1	22	1141	1162	1141	1162	0.97

Sequence Information

Coding Sequence: atgtacaacaaaatGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCGACAGAGAACGATGCGGTCGCCGCGCAGGACATCCTCACGTGCGGCGCATGCCAGAAGACCTTCGCGCTGGCGGACATTGTCCGTTTCATACAGCACAAGGTGTTGCAATGCAACAAGGAGAACTATGGTCAGTGCACCACACAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGCCGTCCACTGAGCCTGGTCAATCGCCGTCCATCAATATCGGCGCCAATCACAGGTCGTAAATCGGCTCCGGTTGGTGTTGCACCACCCACCGCaaccgctgccgctgctgcggccacagctgctgctgctgcggcggcggctgctgctgccgttgcgaGTAGCGCAGCGAGCGgctcacgcattcacacaccaCCGCCCAGTCCGGCGGATCTGCTGGCCGATGGAGCAAGCAGCACGCCCAAACGCCTGGTGGATGAGAACGACAATACAACGCCCAAGGCGGACAGTGAGGCACTGCCTCTGGAATCGCACAGTCCACAGTCCGGCGAGCAGGACGTTCACATCGGACGCGCTGCGATTGAGGATTGCGCGCTGCTCGACGACAAGCCAAAGGTCAAGCAAGAGCCACTCGCCGACGATGAACTGCCACAAgaagaacagcagcaggaagaggagcagcaggagcaggagcggGAGCGAGAGCTGGAGCAATCACAAGTGCTGTCAGCGGGCGACGAGTGCCAACAGCCGCTGGCCAAGCGACCCAAAATGGAGCTCGTCGATGCCGAGGCCAACACGGTGCATACAGAGCCCAGCAACTATACGTGTTCGAGATGCAAGACCCGCTACACCTCCGCCTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGGCAGGTCTGACTGTAGCCACGCCCGCCGCCCTTAATGCAGCCGCATCGGCGGCAGCGAACGCCAGCCTAAGTCCCAATCGCAGCCTCAGTCCctcatcggcagcagcagcagcggcagcagcagcagcagctgttggtaTGCCGCTTCCATTGCACGCGTTGATGGCGCAGGCCGTTGCCtctcagtcgcagtcgcagtcggcATCACAGTCGGCGTCAGCATCGCCTGCCCccaagcgcagcagcagcaacagcagcgcaacAGCAATTATCGGTGGTGCTGGCTCGGCCaacacgagcagcagcagcaatgcgaGCAGCGGTAATTCACCAacgcagcaactgttgcagcagcgtgtacaacagcagcagcagcagcagcagcagcagcagcaacaacaacagcagcagcaacaacatcaacagcaacaacagcagcaacagcaacaacagcaacagaacaTGGCCACGGCAATGGCAGCGGGCATGCGTCATCATCCGCTTCTGGCACCACCAGAGGCAATGCACGCGAATCCGTTCCAGTTGCTCCGCATGCCTCTGCCCCCGGCGCTGGCCCAGGGCAATGTAGTTCCTAGCGTGGCGCCCCTCTTCGGCCGCCCCACGCCCGCCGATCACTATCGCATGGAGCAGTTGGTCAGCGAGCAGTTCCGACATCACGGCTTCAAtctggctgccgctgccgctgccgcccaGGCTCAGTTCAATGCCAcaacccagcagcagcagcaaccgctgCCAGGTATTGCTGTTAATGTTCCTAGCGGCGTAGAGCAGCGGCCGCCTTCGAGCAACAGCAGTCAGCGCGGTTCAGTGCCACCCGCTGCCCTGCCGCCCCCTTCGCTCAGctctcagcaacaacaacagcagcagcagcaacagcaacagcaacagcagcagcagcagcagcagcaacaacagcagcaacttcaacagcagcaacaacagcagcccaATGCTGCCGCTGTGAGTCCAGCGGGCGCCGCCGCCGCTTTGCAACTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCTAGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCAGCCAGCTCTGTGCAGCTGACAGCGACACCACGTCCCCACTCCCTGACGCCGCCTGAAAAGAGCACCGAGAACGGTGGCGGACAGCATGGACAGCTGCCGGGTACGCCACGGAGCACGGCCAGTACGCCGCCCAGCAAGCCACTAGATGGTGAGCGCAGCGAGGCGGAGCTGGAGACGAGCTGCTTTGCTTGCGGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAATCTGATTATCCACCAACGGACGCACACTGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCTCACATCCAGAAGCTGATGAAGCACATGCGCGTTCATCGCAGCCCCGCCGAGGGCCAagatggcagcagcagcaatggcggCGACAACAATCAGGATGGCCATGACGGCGGCAGCAATGCCGACTCTTTGGAGACAAATGAGGCGGACAACGATGAAGATCCGAATCCCGAGGACTCCGACGAGGAGCTCAACGATGAGGATGTCGATGCTGATGCAGAAGAAGATGATGAGGATGAGCTAGATGATTGCGAGGATGTTGACTACGAGGCCGAGGATCTCAGCGTCAACAATCGCATCGATGGCAAGAGCCAGAGCCCAAAGACAACCAGCTCCGGCGCTACCTCGCTGGTGGGCGAGCTCATGGACAAGTTCGGGCTGTCCAACATCGCTCAATACTCGGAGGCCTACAAGCAGGCACTGCAGGAATCTGGCCGCAAGGAGGCGGCTGCTGtggccgcagctgctgctgccgccgctgccgtcgacaacaacaatcgcgGCTCTTCCGTTGCCGGTGGCGCATCAAATGCAACAGGCGATAAGCTGAACGGTCTGCCAGTCGCAGCGTTGCGATTGCGCGACGAGTTCGCCAAGAACTGCAACATGTTCCAGCCTCAGCCGCAGGATGGACCCGCCCAGGTGCCGCTCTTCAATCCGTTTCCCAATCCCTTCGAGCTGTCGAAGCGCATGAAGATGGACGGCGGCGACTGGTGGGGCATGTCGGCGCTGCATCGCAACGAGGCGCTCTTTGAGAATTTGAAGCTGAAGCCACTCGGCTTGGGTGGCGCGAATTCGCTGCTGCAGGGACCGTTGCTGAAGAAGGAGTCGCGCCAAAGGAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACCGTGCACAGGCGCAGCCACACGGGCGAGAAGCCGTACAAGTGCGAGCTATGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGCCGCACCGGTAAGGATGTCTATCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACCCTCGAGAAGCATATGCGCAAGTGTGTGGTCAACCAGGGCaaggcagcagccgctgcggcCAATGCCGCCaatgctgtggctgctgcccaagcagctgctgccgctcaaCAGTTGCAGGCAGCTGCCCaggcacaacagcagcagcagcaacaacagcagcaacagcagcaacagcaacagcaacaattgcccaCGCAGTCGTCGCCCTGCCCAATGAGCGTGGCTGTGGGCTTTCCGCCACAATTCGGACACAATTTGTCGCTGGCGGGCAGTGTGAGCGGCGACAATGATTCAAACGCTTCTTCTAGCCTGCCGGCACACTCCATCTCACTGAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALADIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVGVAPPTATAAAAAATAAAAAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSEALPLESHSPQSGEQDVHIGRAAIEDCALLDDKPKVKQEPLADDELPQEEQQQEEEQQEQERERELEQSQVLSAGDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSRCKTRYTSAWRLIQHVQHSHGVKIYVEAGLTVATPAALNAAASAAANASLSPNRSLSPSSAAAAAAAAAAAVGMPLPLHALMAQAVASQSQSQSASQSASASPAPKRSSSNSSATAIIGGAGSANTSSSSNASSGNSPTQQLLQQRVQQQQQQQQQQQQQQQQQQQHQQQQQQQQQQQQQNMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPSVAPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNATTQQQQQPLPGIAVNVPSGVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQQQQPNAAAVSPAGAAAALQLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAASSVQLTATPRPHSLTPPEKSTENGGGQHGQLPGTPRSTASTPPSKPLDGERSEAELETSCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGSSSNGGDNNQDGHDGGSNADSLETNEADNDEDPNPEDSDEELNDEDVDADAEEDDEDELDDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGSSVAGGASNATGDKLNGLPVAALRLRDEFAKNCNMFQPQPQDGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQQQQLPTQSSPCPMSVAVGFPPQFGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: iTF_00479713; iTF_00572840; iTF_00512972; iTF_00551826; iTF_00599827; iTF_00510049; iTF_00516515; iTF_00476873; iTF_00546891; iTF_00493902; iTF_00502767; iTF_00559733; iTF_00520156; iTF_00473302; iTF_00573560; iTF_00540608;
80% Identity: -