Basic Information

Insect: Drosophila mulleri
Gene Symbol: BCL11A
Assembly: GCA_035047565.1
Location: JAWNPK010000065.1:588155-598178[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.051 3.9 8.2 2.5 1 23 299 322 299 322 0.95

2 6 1.9e-06 0.00014 22.2 1.0 1 23 781 803 781 803 0.98

3 6 0.012 0.91 10.2 4.7 1 23 809 831 809 831 0.99

4 6 1.1e-06 8.5e-05 22.9 3.2 2 23 1106 1127 1105 1127 0.97

5 6 1.4e-05 0.0011 19.4 3.3 1 23 1133 1155 1133 1155 0.99

6 6 2.6e-05 0.002 18.6 0.4 1 22 1163 1184 1163 1184 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.051	3.9	8.2	2.5	1	23	299	322	299	322	0.95
2	6	1.9e-06	0.00014	22.2	1.0	1	23	781	803	781	803	0.98
3	6	0.012	0.91	10.2	4.7	1	23	809	831	809	831	0.99
4	6	1.1e-06	8.5e-05	22.9	3.2	2	23	1106	1127	1105	1127	0.97
5	6	1.4e-05	0.0011	19.4	3.3	1	23	1133	1155	1133	1155	0.99
6	6	2.6e-05	0.002	18.6	0.4	1	22	1163	1184	1163	1184	0.97

Sequence Information

Coding Sequence: atgTTGCCCAAATTTATGAACTGCAAGTGCAAAAGTGTCACACAGCTAGCAGCGGGTGGTGCGGTTGGTGTGGTTGGTGCGGTTGATTCCGACTCGACAGAGAACGATGCGGTCGCCGCGCAGGACATCCTCACGTGCGGCGCATGCCAGAAGACCTTCGCGCTGTCGGACATTGTCCGCTTCATACAGCACAAGGTGATGCAGTGCAACAAGGAGAACTACGGCCAGTGCACCACGCAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGCCGTCCACTGAGCCTGGTCAATCGCCGTCCATCGATATCGGCGCCCATCACCGGTCGCAAATCGGCTCCGGCTGGTGTTGCACCACCCACCGCAaccgcagccgctgctgcggccacagctgctgctgctgcggcggcggcggcggctgctgcagccgtTGCGAGCAGCGCAGCGAGCGGCTCACGCATCCACACACCACCGCCCAGTCCGGCGGATCTGCTGGCGGACGGAGCGAGCAGCACGCCCAAGCGCCTCGTGGATGAGAACGACAATACAACGCCCAAGGCGGACAGCGAGGCACTGCCTCTGCAGCCGCACAGTCCACAGTCCGGCGAGCAGGACGTTCACATCGGGCGCGCTGCGGTCGAGGACTGCGCGCTGCTCGACGACAAGCCAAAGGTCAAGCAGGAGCCCCTCGCCGACGACGAGCTGCCGcaagaggagcagcagcagcagcaggagctggagcaggagcaggagcgggaGCAGGAGCGGGAGCGAGAGCTGGACCAGTCACAAGTGCTGCCAGCGGGCGACGAGTGCCAGCAGCCGCTGGCCAAGCGGCCCAAAATGGAGCTCGTCGATGCCGAGGCGAACACGGTGCATACAGAGCCCAGCAACTATACGTGTTCGAGATGCAAGACCCGCTACACCTCCGCCTGGCGTCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGGCAGGCCTGACTGTGGCCACGCCCGCCGCCCTCAATGCAGCCGCGTCGGCGGCCGCGAACGCCAGCCTAAGCCCCGACCGCAGCCTCAGCCCCTCatcggcggcagcagcggcggcggcggcagcagcagcagcaaccgttggcatgccgctgccattgcacGCGCTGATGGCGCAGGCCGTCGcctcgcagtcgcagtcggcgTCACAGTCGGCGTCAGCATCGCCGGCCCCGAagcgcaccagcagcaacagcagcgcaacgGCAATTGTTGGTGGTGCGGGCTCGgccaacaccagcaacagcagcactgCGAGCAGCGGCAACTCACCgacacagcagctgctgcagcagcgcgtacagcagcagcaccagcagcaacaacaacaacagcagcagcagcagcaacagcaacagcagcaacagaacaTGGCcacggcaatggcagcaggcATGCGGCATCATCCGCTGCTGGCGCCGCCCGAGGCGATGCACGCGAACCCGTTCCAGCTGCTCCGCATGCCGCTGCCCCCGGCGCTGGCCCAGGGCAATGTAGTTCCTAGCGTGGCGCCCCTCTTCGGCCGCCCCACGCCCGCCGACCACTACCGCATGGAGCAGCTGGTCAGCGAGCAGTTCCGCCACCACGGCTTCAATctggctgccgccgctgccgccgcccagGCCCAGTTCAATGCCAccacccagcagcagcagcagcagcagcagccgttgccaGGAGTTGCCGTCAATGTTCCTAGCGGCGTCGAGCCACGGCCGCCCTCGAGCAACAGTAGCCAGCGCGGCTCAGTGCCGCCCGCTGCGCTGCCGCCACCTTCGCTCAGctctcagcagcaacagcaacagcagcaacagcaacaacagcagcaacaacagcaacaacagcagcagcagcagcagcagcaacagcagcagcagcaacaacaactgcaacagcagcagcagcaacctaTTGCCGCCGCTGTGAGTCCAGCGGGCGCCGCTTTGCAACTAGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCTAGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCAGCCAGCTCTGTGCAGCTGACGGCGACCCCGCGGCCCCACTCCCTGACGCCGCCCGAGAAGAGCGCCGAGAATGGTGGCGGACAGCTTGGACAGCTCGGACAGCTGCCGGGCACGCCACGGAGCACGGCCAGCACGCCGCCCAGCAAGCCCTTGGAGGGCGAGCGCAGCGAGGCGGAGCTGGAGGCGAGCTGCTATGCGTGCGGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAATCTGATCATCCACCAGCGGACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCGCACATCCAGAAGCTGATGAAGCACATGCGCGTTCATCGCAGCCCCGCCGAGGGCCaagacggcagcagcagcaacggcggcgACAACAATCAGGATGGCCATGACGGGGGCAGCAACGCCGACTCCTTGGAGACGAACGAGGCGGACAACGACGAGGATCCCAATCCGGAGGACTCCGACGAGGAGCTCAACGACGAGGACGtcgatgcggatgcggatgcggaagAGGACGATGAGGACGAGCTGGACGACTGCGAGGACGTTGACTACGAGGCCGAGGACCTCAGCGTCAACAATCGCATCGACGGCAAGAGCCAGAGCCCAAAGACGACCAGCTCCGGCGCCACCTCGCTGGTGGGCGAGCTCATGGACAAGTTCGGGCTGTCGAACATCGCCCAGTACTCGGAGGCCTACAAGCAGGCGCTGCAGGAGTCGGGCCGCAAGGAGGCGGCTGCTgtggccgcagctgctgccgccgccgctgccgtcgacaacaacaatcgcgGCTCCTCcgtggcaggaggcggctcgaacgcagctggcgctgctggcgATAAGCTGAACGGGCTGCCGGTTGCCGCGCTGCGATTGCGCGACGAGTTCGCCAAGAACTGCAACATGTtccagccgcagccgcaggaCGGGCCCGCCCAGGTGCCGCTCTTCAATCCGTTCCCCAACCCCTTCGAGCTGTCCAAGCGCATGAAAATGGACGGCGGCGACTGGTGGGGCATGTCGGCGCTGCACCGCAACGAGGCGCTGTTCGAGAACCTGAAGCTGAAGCCGCTCGGGCTGGGCGGCGCCAACTCGCTGCTGCAGGGGCCCCTGCTGAAGAAGGAGTCGCGCCAGAGGAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACCGTGCACCGGCGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGCCGCACCGGCAAGGACGTCTATCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCaaggctgcagcagctgcggccaaTGCGGCCagtgctgtggctgctgcccaggcagccgctgccgctcaACAGTTGCAGGCAGCGGCCCaggcccaacagcagcagcagcagcagcagcagcagcagcagcagcaccaacagcagcagcaacagcagcagcagcagcaacagttgcccaCACAGTCGTCGCCCTGCCccatgggcgtggctgtgggcTTTCCGCCGCAATTCGGACACAATCTGTCGCTGGCGGGCAGCGTGAGCGGCGACAACGACTCCAACGCATCTTCCAGCCTGCCGGCGCACTCCATCTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MLPKFMNCKCKSVTQLAAGGAVGVVGAVDSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVMQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPAGVAPPTATAAAAAATAAAAAAAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSEALPLQPHSPQSGEQDVHIGRAAVEDCALLDDKPKVKQEPLADDELPQEEQQQQQELEQEQEREQERERELDQSQVLPAGDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSRCKTRYTSAWRLIQHVQHSHGVKIYVEAGLTVATPAALNAAASAAANASLSPDRSLSPSSAAAAAAAAAAAATVGMPLPLHALMAQAVASQSQSASQSASASPAPKRTSSNSSATAIVGGAGSANTSNSSTASSGNSPTQQLLQQRVQQQHQQQQQQQQQQQQQQQQQQNMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPSVAPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNATTQQQQQQQQPLPGVAVNVPSGVEPRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQQQPIAAAVSPAGAALQLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAASSVQLTATPRPHSLTPPEKSAENGGGQLGQLGQLPGTPRSTASTPPSKPLEGERSEAELEASCYACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGSSSNGGDNNQDGHDGGSNADSLETNEADNDEDPNPEDSDEELNDEDVDADADAEEDDEDELDDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGSSVAGGGSNAAGAAGDKLNGLPVAALRLRDEFAKNCNMFQPQPQDGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAASAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQHQQQQQQQQQQQQLPTQSSPCPMGVAVGFPPQFGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547608;
90% Identity: iTF_00532616;
80% Identity: -