Basic Information

Insect: Drosophila mettleri
Gene Symbol: BCL11A
Assembly: GCA_035047625.1
Location: JAWNPI010000109.1:18875780-18885409[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.046 3.1 8.4 2.4 1 23 283 306 283 306 0.95

2 6 2.5e-06 0.00017 21.8 1.0 1 23 763 785 763 785 0.97

3 6 0.012 0.8 10.3 4.7 1 23 791 813 791 813 0.99

4 6 1.1e-06 7.4e-05 22.9 3.2 2 23 1086 1107 1085 1107 0.97

5 6 1.4e-05 0.00097 19.4 3.3 1 23 1113 1135 1113 1135 0.99

6 6 2.6e-05 0.0018 18.6 0.4 1 22 1143 1164 1143 1164 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.046	3.1	8.4	2.4	1	23	283	306	283	306	0.95
2	6	2.5e-06	0.00017	21.8	1.0	1	23	763	785	763	785	0.97
3	6	0.012	0.8	10.3	4.7	1	23	791	813	791	813	0.99
4	6	1.1e-06	7.4e-05	22.9	3.2	2	23	1086	1107	1085	1107	0.97
5	6	1.4e-05	0.00097	19.4	3.3	1	23	1113	1135	1113	1135	0.99
6	6	2.6e-05	0.0018	18.6	0.4	1	22	1143	1164	1143	1164	0.97

Sequence Information

Coding Sequence: ATGTTTAGAAAATTTACGAACTGCAAGTGCAAAAGTGTCACACAGCCCGCACAGCGGGTGGTGCAGGATTCCGACTCGACAGAGAACGATGCCGTTGCCGCGCAGGACATCCTCACGTGCGGCGCATGCCAGAAAACCTTCGCGCTGTCGGACATTGTCCGTTTCATACAGCACAAGGTTTTGCAGTGCAACAAGGAGAACTATGGCCAGTGCACAACACAGGCGCCCAGCATGGATCGCGATGCCGATGAGGGTCGCCCACTGAGCCTGGTCAATCGCCGTCCATCGATATCGGCGCCAATCACAGGTCGCAAATCGGCTCCGGTTGGTGTTGCACCACCCACCGCaaccgctgccgccgctgcggccacagctgctgctgcggcggcggcggccgcTGCTGTCGCGAGTAGCGCAGCGAGCGGCTCACGCATTCACACACCACCGCCCAGTCCGGCGGATCTGCTAGCCGACGGAGCAAGTAGCACGCCCAAACGCCTGGTGGATGAGAACGACAATACAACGCCCAAGGCAGACAGCGAAGCACTGCCTCTGGAACCACACAGTCCACAGTCCGGCGAGCAGGACGTTCACATCGGACGCTCTGCCATTGAGGACTGCGCGCTGCTAGACGACAAGCCGAAGGTCAAGCAGGAGCCACTCGCCGACGATGAACTGCCACAAGAAGAACAGCAGCacgaggaggagcagcaggagcgGCCGCAAGAACTGGAGCTGTCGCAAGTGCTGCCGGCGGGCGACGAGTGCCAACAGCCGCTGGCCAAGCGACCCAAAATGGAGCTCGTCGATGCCGAGGCCAACACAGTGCATACAGAGCCCAGCAACTATACGTGTTCGAGATGCAAGACCCGCTACAGCTCCGCCTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAAGCAGGTCTGACCGTGGCCACGCCCGCCGCCCTCAACGCAGCCGCATCGGCGGCCGCGAACGCCAGCCTCAGCCCCAGTCGCAGCCTCAGCCCCtcgtcggcagcagcagcggccgcagcagcagcagcagctgttggtatgccgctgccattgcacGCGCTGATGGCGCAGGCCGTTGCCtctcagtcgcagtcgcagtcgcagtcggtAGCTCAGTCGGCGTCAGCATCGCCGGCGCcgaagcgcagcagcagcaacagcagcgccacaGCAATTGTTGGTGGTGCTGGTTCGGCCaacacgagcagcagcagcaatgcgaGCAGCGGTAATTCGCCAacgcagcaactgttgcagcagcgcgttcaacagcagcagcaacaacagcagcaacaacaacaacagcagcagcaacagcaacagcagcagcagcaacaacagcaacaaaacatggccacggcaatggcagcgggcATGCGTCATCACCCGCTTCTGGCACCGCCCGAGGCGATGCACGCGAATCCGTTCCAATTGCTGCGCATGCCGCTGCCCCCGGCTTTGGCCCAGGGCAATGTAGTTCCTAACGTGGCGCCCCTCTTCGGCCGCCCCACGCCTGCCGATCACTATCGCATGGAGCAGCTGGTCAGCGAGCAGTTCCGACACCACGGCTTCAATctggctgccgccgccgctgccgcccaGGCTCAGTTCAATGCCAccacccagcagcagcagccgttgccAGGTGTTGCCGTCAATGTTCCTAGCGGTGTCGAGCAGCGGCCGCCATCGAGCAACAGCAGTCAGCGCGGCTCAGTGCCGCCCGCTGCTCTGCCGCCACCTTCGCTCAGctctcagcaacagcagcagcagcagcagcagcagcagcagcaacagcagcaacaacagcaacaacaacagcagcagcaacttcaacagcagcaacaacaacagcccattgctgccgctgtgagTCCAGCgggtgccgccgccgccgcagccgcttTACAACTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCTAGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCTGCAGCCAGCTCTGTGCAGCTGACAGCGACAACGCGTCCCCACTCCCTGACACCGCCCGAGAAGAGCGCCGAGAACGGCGGCGGTCAGCTCGGACAGCTGCCGGGCACACCACGGAGCACGGCCAGCACGCCGCCAAGCAAGCCGCTCGAGGGTGACCGCACCGAGACGGAGCTGGAGTCGAGCTGCTTTGCGTGCGGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAATCTGATCATACACCAACGTACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCCCACATCCAGAAGCTGATGAAGCACATGCGCGTTCATCGCAGCCCCGCCGAGGGTCaagacggcagcagcagcaatggcggcGACAACAACCAGGACGGCCATGACGGCGGCAGCAATGCCGACTCCTTGGAGACAAACGAGGCGGACAACGACGATGATCCGAATCCCGAGGACTCCGACGAGGAGCTCAACGATGAGGATGTCGATGCGGACGCAGAGGAAGATGATGAGGACGAGCTAGACGACTGTGAGGATGTTGACTACGAAGCCGAGGATCTCAGCGTCAACAACCGCATCGACGGCAAGAGCCAGAGCCCAAAGACAACCAGTTCCGGCGCCACCTCGCTGGTGGGCGAGCTAATGGACAAGTTTGGCCTGTCCAACATAGCCCAGTACTCGGAGGCCTACAAACAGGCTCTGCAGGAGTCTGGCCGCAAGGAGGCGGCTGCCGtggccgcagctgctgcggccgccgctgccgtcgacaacaacaatcgcgGCTCTTCGGTAGCCGGTGGCGCCTCGAATGCAAGTGGCGCGGCTGGCGATAAGCTGAACGGTCTGCCGGTCGCAGCACTGCGATTGCGCGACGAGTTCGCCAAGAACTGCAACATGTTCCAGCCTCAGGCCCAAGATGGACCCGCCCAGGTGCCGCTCTTCAATCCGTTTCCGAATCCCTTCGAGCTGTCCAAGCGCATGAAAATGGATGGCGGCGACTGGTGGGGCATGTCGGCGCTGCATCGCAACGAGGCGATCTTCGAGAACTTGAAACTGAAGCCACTCGGCTTGGGCGGCGCCAACTCGCTGCTACAGGGCCCGTTGCTGAAGAAGGAGTCGCGCCAAAGGAACGACACCTGCGAGTTCTGTGGCAAGGTGTTCAAGAACTGCTCCAACCTGACCGTGCACAGGCGCAGCCACACGGGCGAGAAGCCGTACAAGTGCGAACTATGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGCCGCACCGGCAAGGATGTCTACCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTGGTCAACCAGGGCAAGGCGGCGGCGGCCGCTGCCAATGCAGCCAATGCTGTGGCGGCAGcacaggcagctgctgccgcacaGCAGTTGCAGGCAGCTGCCCAggcccagcaacagcagcaacagcaacaacagcagcagcaacagcagcagcagcaacagttgcccaCGCAGTCGTCGCCCTGCCccatgggcgtggctgtgggCTTTCCGCCACAATTCGGACACAATTTGTCGCTGGCGGGCAGCGTGAGCGGCGACAATGATTCAAACGCTTCCTCCAGTCTGCCGGCCCACTCCATCTCACTGAAGGAGGAGGCATGA
Protein Sequence: MFRKFTNCKCKSVTQPAQRVVQDSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVGVAPPTATAAAAAATAAAAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSEALPLEPHSPQSGEQDVHIGRSAIEDCALLDDKPKVKQEPLADDELPQEEQQHEEEQQERPQELELSQVLPAGDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSRCKTRYSSAWRLIQHVQHSHGVKIYVEAGLTVATPAALNAAASAAANASLSPSRSLSPSSAAAAAAAAAAAVGMPLPLHALMAQAVASQSQSQSQSVAQSASASPAPKRSSSNSSATAIVGGAGSANTSSSSNASSGNSPTQQLLQQRVQQQQQQQQQQQQQQQQQQQQQQQQQQQNMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPNVAPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNATTQQQQPLPGVAVNVPSGVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQQQQPIAAAVSPAGAAAAAAALQLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAASSVQLTATTRPHSLTPPEKSAENGGGQLGQLPGTPRSTASTPPSKPLEGDRTETELESSCFACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGSSSNGGDNNQDGHDGGSNADSLETNEADNDDDPNPEDSDEELNDEDVDADAEEDDEDELDDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGSSVAGGASNASGAAGDKLNGLPVAALRLRDEFAKNCNMFQPQAQDGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEAIFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQQQQLPTQSSPCPMGVAVGFPPQFGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: iTF_00532616;
80% Identity: -