Basic Information

Insect: Drosophila mayaguana
Gene Symbol: BCL11A
Assembly: GCA_037075325.1
Location: JBAMCG010000070.1:87648-97558[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.053 3.7 8.2 2.5 1 23 295 318 295 318 0.95

2 6 2e-06 0.00013 22.2 1.0 1 23 785 807 785 807 0.98

3 6 0.012 0.85 10.2 4.7 1 23 813 835 813 835 0.99

4 6 1.2e-06 7.9e-05 22.9 3.2 2 23 1108 1129 1107 1129 0.97

5 6 1.5e-05 0.001 19.4 3.3 1 23 1135 1157 1135 1157 0.99

6 6 2.8e-05 0.0019 18.6 0.4 1 22 1165 1186 1165 1186 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.053	3.7	8.2	2.5	1	23	295	318	295	318	0.95
2	6	2e-06	0.00013	22.2	1.0	1	23	785	807	785	807	0.98
3	6	0.012	0.85	10.2	4.7	1	23	813	835	813	835	0.99
4	6	1.2e-06	7.9e-05	22.9	3.2	2	23	1108	1129	1107	1129	0.97
5	6	1.5e-05	0.001	19.4	3.3	1	23	1135	1157	1135	1157	0.99
6	6	2.8e-05	0.0019	18.6	0.4	1	22	1165	1186	1165	1186	0.97

Sequence Information

Coding Sequence: ATGTTGCCCAAATTTATGAACTGCAAGTGCAAAAGTGTCACACAGCTAACAGCGGGTGGTGCGTGTGATTCCGACTCGACAGAGAACGATGCGGTCGCCGCGCAGGACATCCTCACGTGCGGCGCATGCCAGAAGACCTTCGCGCTGTCGGACATTGTCCGCTTCATACAGCACAAGGTGTTGCAGTGCAACAAGGAGAACTACGGCCAGTGCACCACACAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGCCGCCCACTGAGCCTGGTCAATCGCCGTCCATCGATATCGGCGCCAATCACAGGTCGCAAATCGGCTCCGGTTGGTGTTGCACCACCCACCGcaaccgctgccgctgctgcggccacagctgctgctgctgctgcggcggcggcggctgctgcagccgttGCGAGCAGCGCAGCGAGCGGCTCTCGCATCCACACACCACCGCCCAGTCCGGCGGATCTGCTGGCGGACGGAGCAAGCAGCACGCCCAAACGCTTAGTGGATGAGAACGACAATACAACGCCCAAGGCGGACAACGAGGCACTGCCTCTGCAGCCTCACAGTCCACAGTCCGGCGAGCAGGACGTTCACATTGGACGCACTGCGGTCGAGGATTGCGCGCTGCTCGACGACAAGCCAAAGGTCAAGCAGGAGCCCCTCGCCGACGATGAGCTGCCgcaagaagagcagcagctcgacgaggagcagcagcaacagcagcagcagcaacaggagcgggagcaggagcgAGAGCTGGAACAGTCACAAGTGCTGCCAGCGGGCGACGAGTGCCAACAGCCGCTGGCCAAGCGACCCAAAATGGAGCTCGTCGATGCCGAGGCCAACACGGTGCATACAGAGCCCAGCAACTATACGTGTTCCAGATGCAAGACCCGCTACACCTCCGCCTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGAGTCAAGATCTACGTGGAGGCAGGTCTGACTGTGGCCACGCCCGCCGCCCTCAATGCAGCCGCATCGGCGGCAGCGAACGCCAGCCTAAGCCCCAATCGCAGCCTCAGTccttcatcagcagcagcagcagcggcggcggcggcggcggcagcagcagcaactgttggcaTGCCGCTGCCTTTGCACGCGCTGATGGCGCAGGCCGTCGcctcgcagtcgcagtcggcgTCACAGTCGGCGTCAGCATCGCCGGTCCcgaagcgcagcagcagcaacagcagcgcaacgGCGATTGTTGGTGGCGCCGGCTCggccaacaccagcagcagcagcactgcgAGCAGCGGCAACTCACCGacacagcaactgttgcagcagcgcgtacagcagcagcagcagcaacagcaacagcagcagcagcaacagcagcagcagcagcaacaacagcaacagcagcaacagaacatGGCCACGGCAATGGCAGCGGGCATGCGCCATCATCCGCTCCTGGCACCGCCCGAGGCGATGCACGCGAACCCGTTCCAGCTGCTCCGCATGCCGCTGCCCCCGGCGCTGGCCCAGGGCAATGTAGTTCCTAGCGTGGCGCCCCTCTTCGGCCGCCCCACGCCCGCCGACCACTACCGCATGGAGCAGCTGGTCAGCGAGCAGTTCCGCCATCACGGCTTCAATCtggctgccgccgccgccgccgcccaggCCCAGTTCAATGCCAccacccagcagcagcagcagcagcagcagcaacagcaacagcaacagccgttGCCAGGTGTTGCCGTCAATGTTCCTAGCGGCGTTGAGCAGCGGCCGCCCTCGAGCAACAGCAGTCAACGCGGCTCAGTGCCGCCCGCTGCGCTGCCGCCTCCTTCGCTCAGctctcagcagcaacagcagcagcagcagcaacagcagcaacaacaacagcagcagcagcaacagcagcaacaacagcagcagcagcagcaacagcagcaacaactgcaacaacaacagcaacccaTTGCCGCCGCTGTGAGTCCAGCGGGCGCCGCTTTGCAACTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCTAGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCAACCAGCTCTGTGCAGCTGACGGCGACCCCGCGGCCCCACTCGCTGACGCCGCCCGAGAAGAGCGCCGAGAACGGTGGCGCACAGCTCGGACAGCTGCCGGGCACGCCTCGGAGCACGGCCAGCACGCCGCCCAGCAAGCCCTTGGAGGGTGAGCGCAGCGAGGCGGAGCTGGAGGCGAGCTGTTATGCGTGCGGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAATCTGATCATCCACCAGCGGACGCACACCGGCGAGAAGCCATACAAGTGCACCGCCTGCGACTTCGAGTGCTCCCACATCCAGAAGCTAATGAAGCACATGCGCGTCCATCGCAGCCCCGCCGAGGGCCaagacggcagcagcagcaacggcggcgACAATAATCAGGATGGCCATGATGGGGGCAGCAACGCCGACTCCTTGGAGACGAACGAGGCGGACAACGACGAGGATCCCAATCCGGAGGACTCCGACGAGGAGCTGAACGACGAGGATGTCGACGCGGATGCGGAAGAAGATGATGAGGACGAGCTGGACGATTGCGAGGACGTTGACTACGAGGCCGAGGATCTCAGCGTCAACAATCGCATCGACGGCAAGAGCCAGAGCCCAAAGACGACCAGCTCCGGTGCCACCTCGCTGGTGGGCGAGCTCATGGACAAGTTCGGCCTGTCCAACATAGCCCAGTACTCGGAGGCCTACAAGCAGGCGCTGCAGGAGTCGGGCCGTAAGGAGGCGGCTGCTgtggccgcagctgctgctgccgccgctgccgtcgacaacaacaatcgcgGCTCCTCCGTAGCCGGTGCCGCCTCGAATGCGGCAGGCGCTGCTGGCGATAAGCTGAACGGGCTGCCGGTTGCCGCGCTGAGGCTGCGCGACGAGTTCGCCAAGAACTGCAACATGTtccagccgcagccgcaggaGGGGCCCGCCCAGGTGCCGCTCTTCAACCCGTTCCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAAATGGACGGCGGCGACTGGTGGGGCATGTCGGCGCTGCACCGCAACGAGGCGCTCTTCGAGAACCTGAAGCTGAAGCCGCTCGGCCTGGGCGGCGCCAACTCGCTGCTGCAGGGACCCCTGCTGAAGAAGGAGTCGCGCCAAAGGAACGACACCTGCGAGTTCTGCGGCAAGGTCTTCAAGAACTGCTCCAACCTGACCGTACACCGGCGCAGCCACACCGGCGAGAAGCCGTACAAGTGTGAGCTGTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGCCGCACCGGCAAGGACGTCTATCGCTGTCGCTTCTGCGACATGCCTTTCAGCGTGCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCaaggcggcggctgctgcggccaaTGCGGCCAatgctgtggctgcagcccaggcagccgctgccgctcaACAGTTGCAGGCAGCTGCTCAggctcagcaacagcagcagcagcaacagcagcagcaacagcagcagcagcaacaattgcccACACAGTCGTCACCCTGCCCCATGGGCGTTGCTGTGGGCTTTCCGCCGCAATTCGGACACAATTTGTCGCTGGCGGGCAGCGTGAGCGGCGACAATGATTCCAACGCTTCTTCCAGCCTGCCGGCGCACTCCATCTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MLPKFMNCKCKSVTQLTAGGACDSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVGVAPPTATAAAAAATAAAAAAAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADNEALPLQPHSPQSGEQDVHIGRTAVEDCALLDDKPKVKQEPLADDELPQEEQQLDEEQQQQQQQQQEREQERELEQSQVLPAGDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSRCKTRYTSAWRLIQHVQHSHGVKIYVEAGLTVATPAALNAAASAAANASLSPNRSLSPSSAAAAAAAAAAAAAATVGMPLPLHALMAQAVASQSQSASQSASASPVPKRSSSNSSATAIVGGAGSANTSSSSTASSGNSPTQQLLQQRVQQQQQQQQQQQQQQQQQQQQQQQQQQNMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPSVAPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNATTQQQQQQQQQQQQQQPLPGVAVNVPSGVEQRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQQPIAAAVSPAGAALQLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSATSSVQLTATPRPHSLTPPEKSAENGGAQLGQLPGTPRSTASTPPSKPLEGERSEAELEASCYACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGSSSNGGDNNQDGHDGGSNADSLETNEADNDEDPNPEDSDEELNDEDVDADAEEDDEDELDDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGSSVAGAASNAAGAAGDKLNGLPVAALRLRDEFAKNCNMFQPQPQEGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQQQLPTQSSPCPMGVAVGFPPQFGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: iTF_00532616;
80% Identity: -