Basic Information

Insect: Drosophila arizonae
Gene Symbol: BCL11A
Assembly: GCA_001654025.1
Location: NW:24740436-24758693[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.043 2.4 8.2 2.5 1 23 294 317 294 317 0.95

2 6 1.6e-06 8.9e-05 22.2 1.0 1 23 780 802 780 802 0.98

3 6 0.0099 0.56 10.2 4.7 1 23 808 830 808 830 0.99

4 6 9.2e-07 5.2e-05 22.9 3.2 2 23 1105 1126 1104 1126 0.97

5 6 1.2e-05 0.00068 19.4 3.3 1 23 1132 1154 1132 1154 0.99

6 6 2.2e-05 0.0012 18.6 0.4 1 22 1162 1183 1162 1183 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.043	2.4	8.2	2.5	1	23	294	317	294	317	0.95
2	6	1.6e-06	8.9e-05	22.2	1.0	1	23	780	802	780	802	0.98
3	6	0.0099	0.56	10.2	4.7	1	23	808	830	808	830	0.99
4	6	9.2e-07	5.2e-05	22.9	3.2	2	23	1105	1126	1104	1126	0.97
5	6	1.2e-05	0.00068	19.4	3.3	1	23	1132	1154	1132	1154	0.99
6	6	2.2e-05	0.0012	18.6	0.4	1	22	1162	1183	1162	1183	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAATGCTGTCGATCAGTGAGGATCATGGATTCCGTTCGCTGAGCCATTCCGACTCGACAGAGAACGATGCGGTCGCCGCGCAGGACATCCTCACGTGCGGCGCATGCCAGAAGACCTTCGCGCTGTCGGACATTGTCCGCTTCATACAGCACAAGGTGATGCAGTGCAACAAGGAGAACTACGGCCAGTGCACCACACAGGCGCCCAGCATGGATCGCGATGCCGACGAGGGCCGTCCGCTGAGCCTGGTCAATCGCCGTCCATCGATATCGGCGCCAATCACAGGTCGCAAGTCGGCTCCGGTTGGTGTGGCACCACCCACCGcaaccgctgccgctgctgcggccacagctgctgctgctgcggcggcggcggcggctgctgcggccgttGCGAGCAGCGCAGCGAGCGGCTCACGCATCCACACACCACCGCCCAGTCCGGCTGATCTGCTGGCGGACGGAGCAAGCAGCACGCCCAAGCGCCTCGTGGATGAGAACGACAATACAACGCCCAAGGCGGACAGCGAGGCGCTGCCTCTGCAGCCGCACAGTCCACAGTCCGGCGAGCAGGACGTTCACATCGGACGCGCTGCGATCGAGGACTGCGCCCTGCTCGACGACAAGCCAAAGGTCAAGCAGGAGCCCCTCGCCGACGACGAGCTGCCgcaagaggagcagcagctcgacgaggagcagcagcaacagcagcagcagcaggaggagcagcgggagcaggagcgggagcgAGAACTGGAGCAGTCGCAGGTGCTGCCAGCGGGCGACGAGTGCCAGCAGCCGCTGGCCAAGCGACCCAAAATGGAGCTCGTCGATGCCGAGGCCAACACGGTGCATACAGAGCCCAGCAACTATACGTGTTCGAGATGCAAGACCCGCTACACCTCCGCCTGGCGCCTCATCCAGCACGTGCAGCACTCGCACGGCGTCAAGATCTACGTGGAGGCAGGTCTGACTGTGGCCACGCCCGCCGCCCTCAACGCAGCCGCGTCGGCGGCCGCGAACGCCAGCCTAAGCCCCAACCGCAGCCTCAGCCCCTCatcggccgcagcagcagcagcggcggcagcagcagcagcagcaaccgttggcatgccgctgccgttgcatGCGCTGATGGCGCAGGCCGTCGcctcgcagtcgcagtcaacGTCACAGTCGGCGTCAGCATCGCCGGCCCcgaagcgcagcagcagcaacagcagcgcaacGGCGATTGTTGGTGGTGCCGGCTCggccaacaccagcagcagcagcactgcgAGCAGCGGCAACTCACCGacacagcaactgttgcagcagcgcgtacagcagcagcagcatcagcagcagcagcaacagcagcagcagcagcaacagcaacaacagcaacagaacatggcaacggcaatggcagcgggCATGCGCCATCATCCGCTCCTGGCGCCGCCCGAGGCGATGCACGCGAACCCGTTCCAGCTGCTCCGCATGCCGCTGCCCCCGGCGCTGGCCCAGGGCAATGTAGTTCCTAGCGTGGCGCCCCTCTTCGGCCGCCCCACGCCCGCCGACCACTACCGCATGGAGCAGCTGGTCAGCGAGCAGTTCCGCCATCACGGCTTCAATctggctgccgccgccgccgccgcccaggCCCAGTTCAACGCCAccacccagcagcagcagcagcagcagcaacaacagcagcagccgctgccaggAGTTGCCGTCAATGTTCCTAGCGGCGTCGAGCCACGGCCGCCCTCGAGCAACAGCAGTCAGCGCGGCTCAGTGCCGCCCGCTGCGTTGCCGCCTCCGTCGCTCAGctctcagcagcaacagcaacagcagcagcagcaacagcagcagcaacaacaacagcagcaacagcagcaccagcaacagcagcaacaacagcagcagcagcaactgcagcagcagcaacagcaacagcaacccaTTGCCGCCGCTGTGAGTCCAGCGGGCGCCGCATTGCAACTGGAACCGCAGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCTAGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCCGCAGCCAGCTCTGTGCAGCTGACGGCGACCCCGCGGCCCCACTCCCTGACGCCGCCCGAGAAGAGCGCCGAGAATGGCGGCGGACAGCTCGGACAGCTGCCGGGCACGCCGCGGAGCACGGCCAGCACGCCGCCCAGCAAGCCCTTGGAGGGCGAGCGCAGCGAGGCGGAGCTGGAGGCGAGCTGCTATGCGTGCGGCTACTGCGACAAGAAGTTCCGCTTCGAGAACAATCTGATCATCCACCAGCGGACGCACACCGGCGAGAAGCCGTACAAGTGCACCGCCTGCGACTTCGAGTGCTCCCACATCCAGAAGCTGATGAAGCACATGCGCGTCCATCGCAGCCCCGCCGAGGGCCaggacggcagcagcagcaacggcggcgaCAACAACCAGGATGGCCATGACGGGGGCAGCAACGCCGACTCCTTGGAGACGAACGAGGCGGACAACGACGAGGATCCCAATCCGGAGGACTCCGACGAGGAGCTCAACGACGAGGACGTCGATGCGGACGCGGATGCGGAAgaggacgacgaggacgagctGGACGATTGCGAGGACGTTGACTACGAGGCCGAGGATCTCAGCGTCAACAATCGCATCGACGGCAAGAGCCAGAGCCCAAAGACGACCAGCTCCGGCGCCACCTCGCTGGTGGGCGAGCTCATGGACAAGTTCGGCCTGTCCAACATCGCCCAGTACTCGGAGGCCTACAAGCAGGCGCTGCAGGAGTCGGGCCGCAAGGAGGCGGCTGCCgtggccgcagctgctgccgccgccgccgccgtSgacaacaacaaccgcggCTCCTCCGTGCCAGGAGGCGCCTCGAatgcagcaggcgctgctggCGATAAGCTGAACGGGCTGCCGGTGGCCGCGCTGCGGCTGCGCGACGAGTTCGCCAAGAACTGCAACATGTtccagccacagccgcaggaCGGGCCCGCCCAGGTGCCGCTCTTCAATCCGTTCCCCAATCCCTTCGAGCTGTCCAAGCGCATGAAAATGGACGGCGGCGACTGGTGGGGCATGTCGGCGCTGCACCGCAACGAGGCGCTGTTCGAGAACCTCAAGCTGAAGCCGCTCGGGCTGGGCGGCGCCAACTCGCTGCTGCAGGGACCCCTGCTGAAGAAGGAGTCGCGCCAGAGGAACGACACCTGCGAGTTCTGCGGCAAGGTGTTCAAGAACTGCTCCAACCTGACCGTGCACCGGCGCAGCCACACCGGCGAGAAGCCGTACAAGTGCGAGCTGTGCTCCTACGCCTGCGCCCAGAGCTCCAAGCTCACCCGCCACATGAAGACGCACGGCCGCACCGGCAAGGACGTCTACCGCTGTCGCTTCTGCGACATGCCCTTCAGCGTGCCCTCCACCCTCGAGAAGCACATGCGCAAGTGCGTCGTCAACCAGGGCAAGGCGGCGGCCGCTGCGGCGAATGCGGCcaatgctgtggctgctgcccaggcagccgctgccgcgCAACAGTTGCAGGCAGCTGCCcaggcccagcagcagcagcagcagcaacaacagcagcagcaacaacagcagcagcagcaacagttgcccaCACAGTCGTCGCCCTGCCccatgggcgtggctgtgggcTTTCCGCCGCAATTCGGACACAATCTGTCGCTGGCGGGCAGCGTGAGCGGCGACAACGACTCCAACGCTTCTTCCAGCCTGCCGGCGCACTCCATCTCGCTGAAGGAGGAGGCATGA
Protein Sequence: MYNKMLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACQKTFALSDIVRFIQHKVMQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPVGVAPPTATAAAAAATAAAAAAAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKADSEALPLQPHSPQSGEQDVHIGRAAIEDCALLDDKPKVKQEPLADDELPQEEQQLDEEQQQQQQQQEEQREQERERELEQSQVLPAGDECQQPLAKRPKMELVDAEANTVHTEPSNYTCSRCKTRYTSAWRLIQHVQHSHGVKIYVEAGLTVATPAALNAAASAAANASLSPNRSLSPSSAAAAAAAAAAAAATVGMPLPLHALMAQAVASQSQSTSQSASASPAPKRSSSNSSATAIVGGAGSANTSSSSTASSGNSPTQQLLQQRVQQQQHQQQQQQQQQQQQQQQQQNMATAMAAGMRHHPLLAPPEAMHANPFQLLRMPLPPALAQGNVVPSVAPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNATTQQQQQQQQQQQQPLPGVAVNVPSGVEPRPPSSNSSQRGSVPPAALPPPSLSSQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQQQQLQQQQQQQQPIAAAVSPAGAALQLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSAASSVQLTATPRPHSLTPPEKSAENGGGQLGQLPGTPRSTASTPPSKPLEGERSEAELEASCYACGYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPAEGQDGSSSNGGDNNQDGHDGGSNADSLETNEADNDEDPNPEDSDEELNDEDVDADADAEEDDEDELDDCEDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVDNNNRGSSVPGGASNAAGAAGDKLNGLPVAALRLRDEFAKNCNMFQPQPQDGPAQVPLFNPFPNPFELSKRMKMDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQQQQQQQQQQQQLPTQSSPCPMGVAVGFPPQFGHNLSLAGSVSGDNDSNASSSLPAHSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519433;
90% Identity: iTF_00532616;
80% Identity: -