Dkan003007.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kanekoi
Gene Symbol
-
Assembly
GCA_037075305.1
Location
JBAMCE010000095.1:6746957-6752483[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0015 0.1 13.2 1.3 1 23 147 169 147 169 0.98
2 14 0.00015 0.0097 16.4 1.3 1 23 394 416 394 416 0.98
3 14 1.7 1.2e+02 3.6 0.8 1 23 422 445 422 445 0.94
4 14 1.3 85 4.0 0.2 1 23 472 495 472 495 0.92
5 14 0.0013 0.085 13.4 1.9 3 23 754 774 753 774 0.92
6 14 0.052 3.4 8.4 1.4 1 23 780 803 780 803 0.98
7 14 0.35 23 5.7 1.5 2 23 840 861 839 862 0.92
8 14 0.009 0.59 10.8 0.8 1 23 883 906 883 906 0.97
9 14 0.017 1.1 9.9 0.4 1 23 1135 1158 1135 1158 0.91
10 14 0.00071 0.047 14.2 4.7 1 23 1171 1193 1171 1193 0.98
11 14 0.041 2.7 8.7 0.0 2 23 1199 1221 1198 1221 0.95
12 14 0.00071 0.047 14.2 3.3 2 23 1230 1254 1229 1254 0.90
13 14 0.048 3.2 8.5 0.4 1 23 1259 1281 1259 1281 0.97
14 14 0.0056 0.37 11.4 1.6 1 23 1287 1310 1287 1310 0.96

Sequence Information

Coding Sequence
ATGGCGCACAAACGAGTGAAAACAGAGGACATGGAAGTGAATTACAAATTTGCGTGTCGCTGTTGCCTCAAATCGGAGGCGGAATTCTTTAAGCTGGACTCACTAATTGAGTGTGGCATAAGCGAGCATGACGCGTCCTCTACTAAAATACCCCTGATACGATTACTATTATTCTGCATGCGCACTGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTCGAGTGCAGTAAAAGTTTACAAATCGCCTACTATTTCATACAGAACGGCTTGCGCGCACATGAAATACTCTGTCGCAAGCTGTGCCCTGGGAAGCTAAAGACGACAACAACTCGGTCGAACGGACAACATGCATCGCTATGGCCCGAGTCAAATGCCAGAGATGACGCGTCGCTGCCCAGGCTCTGGGACCAGAAGCCCCAAAAGCCCGCTGTGCGACACGAATGCAAAGTATGCGGTGCGATTGTGCACAATCGCATGGAGCTCAAACAGCACATACGCATGCACACAGagtcATCGCAACATCACTGCAAATTGTGCAACTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCACACGGATTGACAGCTGCCCAAATTGAGCAACAGATCAAAATCAGAAGATCGATacaggcggcagcaacaactgcagcgacaacaaccgCAATAGAAACTCCTGCAGACGATGGTCAGGTGAAGGTGTGCACACTGGAGGACATGGAGCTGCTAATACCCACTGTGCTGACGCCAGAGGATTTTACGCATCCACAACTGGATGCGGATCAGTTGCGTGATATTGAACAACAATTGGCGAACGCGCTGCCCGTCCCACAGTCCAATTTAGCTGGCATACCGGCTGAGCCGACGATAGATGCTGGGAGTAGCGCCAATGTTAGCATCGGTGCGGAGTTTCTGGTCATGCCCGATGGCTCTTTGCAGCAAGTGAATGATGCCGGTGTGGTTTTCGAATACATTGATGATAGCAAAAATACCAATACGACAAGCAATATGACATTGCAGAGTCTATTGGGCGATTCCAAGACAGATTTATCCTATAATGCCATGGATATCGATCTGAGTCATATGGTTGTCGACAATGCGCTGCCACAGATAacagTAAAGCCAAAACCGCGCCCGGCACCTGCGTCAACTGGTGCGCTGAAACACAAATGCAAACTGTGCCCCAAGGCATTTCCAACGGTGGCTCGCCTGAAATCTCATCAATTAACGCATAGTCATTTGCCGAAATTCTATTGTGATCAGTGCTCCTATTATTCGCTGCGTAGCGCCGATCTTATCCAGCACTATACGACAGAGCACAAGTCTTGCATTAGCGAGAGTCGTTCGAATCATTTGGATAAGGCGCAACTCACTGAACCGGCGGACAGAAGTCGCATATATTCATGCGATATGTGTTTGTTTGAGGCACCCAGTAGTGGCCAGTTACGTGTACATTATAGCGATAAGCATCTGATAGTGCCCAGTGAGGTACAGCTGCGCCCCAACTGGGCGTATGAGTCAAAGGATAGGAACGCCAGCTCAACGCTTACCAGTGGCAATAGTACGGCAACTCAGCTAGATATTCCACTGGGTATCAAATATCCACCCATGACGtcggcgacagcaacagcgacaagtGCGCCAACAGCTACCatacagcagccgccgcaggcaacaacaacaactgtggtTACGCAAAGTGGTGACATTAATGTTGTCGTTGATGCCACATCATTGTTCTATGCAGCGGGCCAGTTACCAGCAGCGGGtgctccaacaacaacagctacagatTCAGGAACATTTGCAATATTCCCAGAGCAATCTTTTGCCAGCAGCCtgacaacatcaacaataacGGGGGAGCCAAGCGGTGTAGCGCCTGCCACGACCACTTCAAATCCAAACACCAGCATATTTGGCGATATGCAGGATTTTATAGATAACACTGATGTGGCGGCCATATGCACCATACCCGCAGATGACATGCCAGTGGTCGATGGCGATGATATTGTTAttgataacaataatataagcTTGGATTTCGATGCAGAAAACTTATTCGAAGACTTTGAGGATGTGGAAGTGGGCGAAgaggatgacgatgatgaggatgatgccGAAAATGAGGATGAAAATGATAACAATGATGCGGCAGCCGATCAAAATCTGTTGCTCACCAGCGATGATGACGATGTGGATGACTTTGATGACGAACAATCGAAGCATTTGCAGAAACCATATTGCATCTATTGTAATAAAAAGTTTACCAGCCAATATAAGTTCGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCCTATCGCTGTGAACTGTGCACTAATCTGTACAATATGAAACGCCTTCTCATACGGCATTATAAGACGGTGCACAAACGCATGCCTACTCGGGATATGGTGCAAGCTAAGGGCGACAAGGTGTCCGTGCCGCGAACAACCATTGAAAAGATAAACACCTATGTTGACAAACCACCCACGCTAATGTGTGCCAAGTGTCCCTTTGAATGCGAACAGGAGGGTGAAATGCGTAAGCATCTAAATGCACATCATGGCATCAACGATGGCGTTTCTGTGCATGCCAACGAGGTGTTTATCATACGCAAACTGCCCTATGACTGCCCACGCTGTATTCGCTCATTTGCGGCCAAGCGCACGCTGACACGACATTTGCAACGTAGCCATTTAGTAGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCGGCGGccacaacaaccacaccaACGGCTACAACCACATTGCCGTTGAACGCTAGTGATggcaataaaacaacaacaacaacaacaatggcacaaCAGGATTCCAACATGTTGGCGCAGCATGACGCTGGCAATGTCGATGTCGACgtcgatggcgatggcgatggcgatggcgatggaaAATGCGACAGAGACATAGGATTCAAAACGGAAATGATAGACACAGATTTAAAAATCgaagctacaacaacaatggcaacacaagaaaaaaatgcaacaacaactgaaacgacaacagcagaaacagaAGTTGCAACAATAGCAAAGACAGAAGTCACAGATGCTGCAACAAATACTACAGCAATATCAACGACAAcatcaggagcagcagcagcgtcaacagcaacaacaacaactgcaggcTCAACACTCTTTCCAACGCCCACGCCATTTGACTACGATTTTGACTTTATTGGCAGTGGTGCACATGCCACGACCattaagaacaacaacgacagcttCAGTATTGAACCCAGCCCCAGTCATCTATTGAATGGCAGCGACAAGCTACTGACCGCTGCGTTGGAGCCATCGCCGATAAAAGATTTACGTTCGCGTTTACCGCGCACACCCATATTTGTGTGCAAGCAATGCAATCAGACCTTTGATGAGCTTGGCAAGCTGTTGCAGCACGAATTGGAGCAACATTCCAGCAGCATCGTATCGCCGCGTGTCACTCACCAGCATCAGTGCAAGATCTGTAAAACGACCTACCGCACCGTAACGCTACTAAATTACCATATGAAAAGGCACACGCCGGCTAAAGTTCCATGCGAACAATGCCCCAAGGAGTTTTTGAATAGCCCAGATTTGGATCAGCACATACAGTCAGATCACAGCGCTAATACAACAACACCACTCAAATGCGGCATAGATGGTTGCGAGAAGacatttaattacaaacaTCATTTGAAACGGCATCAGACAGCCTCTCATACGCCGGTGCACTATATCTGTCCGGAGTGTGGGCGCGACATGTTGACTAGTCTGCATCTCAGGAATCACATGTCAATCCACAAGGGCACACATTCTTACAAGTGTCCCAAATGCGTTCGCACCTATATGCGACGCAAACCtttTCGAAGACATGCTTTACGTGAGCACAAATGGGAGCTGACTGAGGAGGAAATAGACAAAATATATAGCATAAATGATACACCACCATCAATCAAATTGCGGCAACGACGATCAGTGAAGGTTGAGAGCGAGAACTCTGATTAA
Protein Sequence
MAHKRVKTEDMEVNYKFACRCCLKSEAEFFKLDSLIECGISEHDASSTKIPLIRLLLFCMRTENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKTTTTRSNGQHASLWPESNARDDASLPRLWDQKPQKPAVRHECKVCGAIVHNRMELKQHIRMHTESSQHHCKLCNFVTLKHRQLPEHYRKAHGLTAAQIEQQIKIRRSIQAAATTAATTTAIETPADDGQVKVCTLEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLANALPVPQSNLAGIPAEPTIDAGSSANVSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNTNTTSNMTLQSLLGDSKTDLSYNAMDIDLSHMVVDNALPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCISESRSNHLDKAQLTEPADRSRIYSCDMCLFEAPSSGQLRVHYSDKHLIVPSEVQLRPNWAYESKDRNASSTLTSGNSTATQLDIPLGIKYPPMTSATATATSAPTATIQQPPQATTTTVVTQSGDINVVVDATSLFYAAGQLPAAGAPTTTATDSGTFAIFPEQSFASSLTTSTITGEPSGVAPATTTSNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDAENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVPRTTIEKINTYVDKPPTLMCAKCPFECEQEGEMRKHLNAHHGINDGVSVHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTPTATTTLPLNASDGNKTTTTTTMAQQDSNMLAQHDAGNVDVDVDGDGDGDGDGKCDRDIGFKTEMIDTDLKIEATTTMATQEKNATTTETTTAETEVATIAKTEVTDAATNTTAISTTTSGAAAASTATTTTAGSTLFPTPTPFDYDFDFIGSGAHATTIKNNNDSFSIEPSPSHLLNGSDKLLTAALEPSPIKDLRSRLPRTPIFVCKQCNQTFDELGKLLQHELEQHSSSIVSPRVTHQHQCKICKTTYRTVTLLNYHMKRHTPAKVPCEQCPKEFLNSPDLDQHIQSDHSANTTTPLKCGIDGCEKTFNYKHHLKRHQTASHTPVHYICPECGRDMLTSLHLRNHMSIHKGTHSYKCPKCVRTYMRRKPFRRHALREHKWELTEEEIDKIYSINDTPPSIKLRQRRSVKVESENSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00534822;
90% Identity
iTF_00563426; iTF_00617187; iTF_00506390; iTF_00531201; iTF_00491027;
80% Identity
-