Basic Information

Insect: Drosophila borealis
Gene Symbol: -
Assembly: GCA_035045885.1
Location: JAWNOR010000206.1:3643193-3648720[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00038 0.031 15.0 0.5 1 23 146 168 146 168 0.98

2 14 0.00014 0.012 16.4 1.3 1 23 393 415 393 415 0.98

3 14 1.7 1.4e+02 3.6 0.8 1 23 421 444 421 444 0.94

4 14 1.3 1e+02 4.0 0.2 1 23 471 494 471 494 0.92

5 14 0.0013 0.1 13.4 1.9 3 23 753 773 752 773 0.92

6 14 0.05 4.1 8.4 1.4 1 23 779 802 779 802 0.98

7 14 1.7 1.4e+02 3.5 1.2 2 23 839 860 838 861 0.85

8 14 0.0088 0.71 10.8 0.8 1 23 882 905 882 905 0.97

9 14 0.016 1.3 9.9 0.4 1 23 1130 1153 1130 1153 0.91

10 14 0.00034 0.028 15.2 4.3 1 23 1166 1188 1166 1188 0.98

11 14 0.0055 0.44 11.4 0.1 2 23 1197 1219 1196 1219 0.95

12 14 0.00078 0.064 14.1 4.1 2 23 1228 1252 1227 1252 0.90

13 14 0.047 3.8 8.5 0.4 1 23 1257 1279 1257 1279 0.97

14 14 0.0055 0.45 11.4 1.6 1 23 1285 1308 1285 1308 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00038	0.031	15.0	0.5	1	23	146	168	146	168	0.98
2	14	0.00014	0.012	16.4	1.3	1	23	393	415	393	415	0.98
3	14	1.7	1.4e+02	3.6	0.8	1	23	421	444	421	444	0.94
4	14	1.3	1e+02	4.0	0.2	1	23	471	494	471	494	0.92
5	14	0.0013	0.1	13.4	1.9	3	23	753	773	752	773	0.92
6	14	0.05	4.1	8.4	1.4	1	23	779	802	779	802	0.98
7	14	1.7	1.4e+02	3.5	1.2	2	23	839	860	838	861	0.85
8	14	0.0088	0.71	10.8	0.8	1	23	882	905	882	905	0.97
9	14	0.016	1.3	9.9	0.4	1	23	1130	1153	1130	1153	0.91
10	14	0.00034	0.028	15.2	4.3	1	23	1166	1188	1166	1188	0.98
11	14	0.0055	0.44	11.4	0.1	2	23	1197	1219	1196	1219	0.95
12	14	0.00078	0.064	14.1	4.1	2	23	1228	1252	1227	1252	0.90
13	14	0.047	3.8	8.5	0.4	1	23	1257	1279	1257	1279	0.97
14	14	0.0055	0.45	11.4	1.6	1	23	1285	1308	1285	1308	0.96

Sequence Information

Coding Sequence: ATGGCGCACAAACGAGTGAAAACAGAGGACATGGAAGTGAATTACAAATTTGCGTGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTTAAGCTGGACTCACTAATCGAGTGTGGCATTAGCGAACATGACGCGTCCTCTACTAAAATACCCATGATACGATTACTATTATTCTGCATGCGCACTGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTCGAGTGTAGTAAAAGTTTGCAAATTGCCTATTATTTCATACAGAACGGCTTGCGCGCACATGAAATACTCTGTCGCAAGCTGTGCCCTGGGAAGCTAAAGACAACAACTCGTTCGAACGGACAACATGCATCGCCATGGCTGGAGACAAACGACAGAGATGACGCGTCGCTGCCCAGGCAATGGGAGCTGAAACCTCAAAAGCCCGCTGTACGACACGAATGCAAAGTATGCGGTGCGATTGTATACAATCGCATGGAGCTCAAACAGCACATACGCATGCACACAGAGTCATCGCAACATAAGTGCAAATTGTGCAACTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCACACGGCTTGACAGCTGCCCAAATTGAGCAACAGATCAAAATCAGAAGATCTATGCAGGCGGCTGCAACAacggcagcgacaacaaccGCAATAGAAACTCCTGCAGACGATGGTCAGGTGAAGGTGTGCACACTGGAGGACATGGAGTTACTGATACCCACCGTGCTGACGCCAGAGGATTTTACGCATCCACAACTGGATGCGGATCAGTTGCGTGATATTGAGCAACAATTGGCGAACGCGCTGCCCGTCCCACAGTCCAATTTAGGTGGCATACCAGCTGAGCCGACGATAGATGCTGGCAGTAGCGCGAATGTTAGCATCGGTGCCGAGTTTCTGGTCATGCCTGATGGCTCTTTGCAGCAAGTAAATGATGCCGGTGTGgtttttgaatatattgatGATAGCAAAAACACCAATACGACAACCAATATGACATTGCAGAGTCTATTGGGCGATTCCAAGACAGATTTAACCTATAATGCCATGGATATCGATCTGAGTCATATGGTTGTCGACAATGCGCTGCCACAGATaacagttaagCCAAAACCGCGCCCGGCACCTGCGTCTACTGGTGCCCTGAAACACAAATGCAAACTGTGCCCCAAGGCATTTCCAACGGTAGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCGAAATTCTATTGTGATCAGTGCTCCTATTATTCGCTGCGTAGCGCCGATCTTATCCAGCACTATACGACAGAGCACAAGTCTTGCATTAGCGAGAGTCGTTCGAATCATTTGGAAAAGGCGCAACTCACTGAGCCGGCGGACAGAAGTCGCATATATTCATGCGATATGTGTTTGTTTGAGGCACCCAGCAGTGGGCAGTTACGTGTACATTATAGCGACAAGCATCAGATAGTGCCCAGTGAGGTACAGCTGCGCCCTAACTGGGCGTATGAGTCAAAGGATAGGAATGCTGGCTCAACGCTAACCAGTGGCAATAGTACTACAAATCAGCTAGATATTCCACTGGGTATCAAATATCCACCCATGACGTctgcgacagcaacagcgacaattGGGCCAACAGTTAACAtacagcagccgccgcaggcaacaacaacaactgtggTTACGCAAAGTGGTGACATTAATGTTGTGGTGGATGCCACATCATTGTTCTATGCAGCGGGCCAGTTACCAGCAGCTGGTGCTCCAACAACACCAGCTACAGATTCAGAAACATTTGCAATATTCCCAGAGCAATCTTTTGCCAACAGCTTGACAAAGTCAACAATAACGAGGGAGCCAAACGGTGTGGCACCTGCCACGGTCACTTCAAATCCAAACACCAGCATATTTGGTGATATGCAGGATTTTATAGATAACACTGATGTGGCGGCCATATGCACCATACCCGCCGATGATATGCCAGTGGTCGACGGCGATGATATTGTTAttgataacaataatataagcCTGGATTTTGATGCAGAAAACTTATTTGAAGACTTTGAGGATGTGGAAGTGGGCGAAgaggatgacgatgatgaggaTGATGCCGAAAATGATGATGAGAATGATAACAATGATGCGGCAGCCGATCAAAATCTGTTGCTCACCAGCGATGATGACGATGTGGATGACTTTGATGACGAACAATCGAAGCATTTGCAGAAACCATATTGCATCTATTGTAATAAAAAGTTTACCAGCCAATATAAGTTCGAGAATCATATGTTTGTGCATCGCGGCTTGGCACCTTATCGCTGTGAACTGTGCACCAATCTATACAATATGAAACGCCTACTCATACGGCATTATAAGACGGTGCACAAACGCATGCCCACTCGGGACATGGTGCAAGCAAAGGGCGACAAGGTGTCCGTGCCGCGTACAACCATTGAAAAGATAAACGTTTATGTTGACAAACCACCCATGCTAATGTGTGCTAAGTGTCCCTTCGAATGCGAAGAGGAAGGTGAAATGCGTAAGCATCTAAATGCACATCATGGCATTAACGATGGCGTCTCTGTGCACGCCAACGAGGTGTTTATCATACGCAAACTGCCCTATGACTGTCCACGCTGCATTCGCTCATTTGCGGCCAAGCGCACGCTGACACGACATTTGCAACGTAGCCATTTAGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCGGCGGCCACAACGACCACACCAACGGCTACAACCACATTGCCGTTGAACGCTAGTGATggcaataaaacaacaacaacaacaacaacggcacaACAGGATTCCAACATGTTGGCGCAGCATGATGCTGGCAATGTCGATGTCGACgtcgatggcgatggcgatggaAAATGCGACAGGGACACAGGATTCAAAACGGAAATATTAGACACAGATTTAAAAATCGAAGCCACAACTACAACGGCAACACAAGaaacaaatgcagcagcaactgaaacgacagcagcagaaaaagaaGTTGCAACAATAGCAAAGACAGAAGCCACagaagctgcagcaacaaatacTACAGCAATATCAACGACAACatcaggagcagcagcagcatcaacaacaacaactactgcAGGCTCAACACTCTTTCCAACGCCCACGCCATTTGACTATGATTTTGACTTTATTGGCAGTGGTGCacttgccacgcccattaagaacaacagcgacagcttCAACATTGCACCCAGCCCCAGTCATCTATTGAATGGCAGCGACAAGCTACTGACCGCTGCGTTGGAGCCATCGCCAATTAAAGATTTACGTTCTCGCTTACCGCGCACACCCATATTTGTGTGCAAGCAATGCAATCAGACCTTTGATGAGCTTGGCAAGCTGTTGCAGCACGAATTGGAGCAACATTCCAGCAGCGTTGTATCGCCGCGCGTCAGTCACCAGCATCAGTGCAAGATCTGTAACACAACCTACCGCACCATAACGCTACTAAATTACCATATGAAACGGCATACGCCGGCCAAAGTTCCAAAAGTTCCATGCCAGCAATGCCCCAAGGAGTTTTTGAATAGCTCAGATTTGGATCAGCACATACAGTCAGATCATAGCGCTAATACAACGACACCACTCAAATGCGGCATAGATGGTTGCAAGAAGACATTCAACTACAAACATCATTTGAAACGGCATCAGACAGCCTCTCATACGCCGGTGCACTATATCTGTCCGGAGTGTGGACGCGACATGTTGACTAGTCTGCATCTGAGGAATCACATGTCAATCCACAAGGGCACACATTCTTACAAGTGTCCCAAATGCGTTCGCACCTATATGCGACGTAAGCCaTTTCGAAGACATGCTTTACGTGAGCACAAATGGGAGCTGACTGAGGAGGAAATAGACAAAATATATAGCATAAATGATACACCACCATCAATCAAATTGCGCCAACGACGATCAGCGAAGGATGAGAACGAGAACTCTGATTAA
Protein Sequence: MAHKRVKTEDMEVNYKFACRCCLKSEAEFFKLDSLIECGISEHDASSTKIPMIRLLLFCMRTENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKTTTRSNGQHASPWLETNDRDDASLPRQWELKPQKPAVRHECKVCGAIVYNRMELKQHIRMHTESSQHKCKLCNFVTLKHRQLPEHYRKAHGLTAAQIEQQIKIRRSMQAAATTAATTTAIETPADDGQVKVCTLEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLANALPVPQSNLGGIPAEPTIDAGSSANVSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNTNTTTNMTLQSLLGDSKTDLTYNAMDIDLSHMVVDNALPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCISESRSNHLEKAQLTEPADRSRIYSCDMCLFEAPSSGQLRVHYSDKHQIVPSEVQLRPNWAYESKDRNAGSTLTSGNSTTNQLDIPLGIKYPPMTSATATATIGPTVNIQQPPQATTTTVVTQSGDINVVVDATSLFYAAGQLPAAGAPTTPATDSETFAIFPEQSFANSLTKSTITREPNGVAPATVTSNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVPRTTIEKINVYVDKPPMLMCAKCPFECEEEGEMRKHLNAHHGINDGVSVHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTPTATTTLPLNASDGNKTTTTTTTAQQDSNMLAQHDAGNVDVDVDGDGDGKCDRDTGFKTEILDTDLKIEATTTTATQETNAAATETTAAEKEVATIAKTEATEAAATNTTAISTTTSGAAAASTTTTTAGSTLFPTPTPFDYDFDFIGSGALATPIKNNSDSFNIAPSPSHLLNGSDKLLTAALEPSPIKDLRSRLPRTPIFVCKQCNQTFDELGKLLQHELEQHSSSVVSPRVSHQHQCKICNTTYRTITLLNYHMKRHTPAKVPKVPCQQCPKEFLNSSDLDQHIQSDHSANTTTPLKCGIDGCKKTFNYKHHLKRHQTASHTPVHYICPECGRDMLTSLHLRNHMSIHKGTHSYKCPKCVRTYMRRKPFRRHALREHKWELTEEEIDKIYSINDTPPSIKLRQRRSAKDENENSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00534822;
90% Identity: iTF_00526843;
80% Identity: -