Basic Information

Insect: Drosophila lacicola
Gene Symbol: -
Assembly: GCA_035045355.1
Location: JAWNPB010000017.1:41973-47523[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0004 0.027 15.0 0.5 1 23 147 169 147 169 0.98

2 14 0.00015 0.01 16.4 1.3 1 23 394 416 394 416 0.98

3 14 1.8 1.2e+02 3.6 0.8 1 23 422 445 422 445 0.94

4 14 1.3 88 4.0 0.2 1 23 472 495 472 495 0.92

5 14 0.0013 0.089 13.4 1.9 3 23 754 774 753 774 0.92

6 14 0.052 3.5 8.4 1.4 1 23 780 803 780 803 0.98

7 14 1.8 1.2e+02 3.5 1.2 2 23 840 861 839 862 0.85

8 14 0.0091 0.62 10.8 0.8 1 23 883 906 883 906 0.97

9 14 0.017 1.2 9.9 0.4 1 23 1137 1160 1137 1160 0.91

10 14 0.00079 0.053 14.1 4.8 1 23 1173 1195 1173 1195 0.98

11 14 0.0057 0.38 11.4 0.1 2 23 1201 1223 1200 1223 0.95

12 14 0.00081 0.055 14.1 4.1 2 23 1232 1256 1231 1256 0.90

13 14 0.049 3.3 8.5 0.4 1 23 1261 1283 1261 1283 0.97

14 14 0.0057 0.39 11.4 1.6 1 23 1289 1312 1289 1312 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0004	0.027	15.0	0.5	1	23	147	169	147	169	0.98
2	14	0.00015	0.01	16.4	1.3	1	23	394	416	394	416	0.98
3	14	1.8	1.2e+02	3.6	0.8	1	23	422	445	422	445	0.94
4	14	1.3	88	4.0	0.2	1	23	472	495	472	495	0.92
5	14	0.0013	0.089	13.4	1.9	3	23	754	774	753	774	0.92
6	14	0.052	3.5	8.4	1.4	1	23	780	803	780	803	0.98
7	14	1.8	1.2e+02	3.5	1.2	2	23	840	861	839	862	0.85
8	14	0.0091	0.62	10.8	0.8	1	23	883	906	883	906	0.97
9	14	0.017	1.2	9.9	0.4	1	23	1137	1160	1137	1160	0.91
10	14	0.00079	0.053	14.1	4.8	1	23	1173	1195	1173	1195	0.98
11	14	0.0057	0.38	11.4	0.1	2	23	1201	1223	1200	1223	0.95
12	14	0.00081	0.055	14.1	4.1	2	23	1232	1256	1231	1256	0.90
13	14	0.049	3.3	8.5	0.4	1	23	1261	1283	1261	1283	0.97
14	14	0.0057	0.39	11.4	1.6	1	23	1289	1312	1289	1312	0.96

Sequence Information

Coding Sequence: ATGGCGCACAAACGATTGAAAACAGAGGACATGGAAGTGAATTACAAATTTGCGTGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTTAAGCTGGACTCACTAATCGAGTGTGGCATTAGCGAACATGACGCGTCCTCTACTAAAATACCCCTGATACGATTACTATTATTCTGCATGCGCACTGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTCGAGTGTAGTAAAAGTTTGCAAATTGCCTACTATTTCATACAGAACGGCTTGCGCGCACATGAAATACTCTGTCGCAAGCTGTGCCCTGGGAAGCTAAAGACAACAACTCGTTCGAACGGACAACATGCATCGCAATGGCTGGAGCAGACAAATGCCAGAGATGACGCGTCGCTGCCCAGGCAATGGGAGCTGAAACCTCAAAAGCCCGCTGTACGACACGAATGCAAAGTATGCGGTGCGATTGTGTACAATCGCATGGAGCTCAAACAGCACATACGCATGCACACAGagtcaTCGCAACATCAGTGCAAATTGTGCAACTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCACACGGCTTGACAGCTGCCCAAATTGAGCAACAGATCAAAATCAGAAGATCTATGCAGGCGGCTGCAACAACGGCAGCGATAACAACCGCAACAGAAACTCCTGCAGACGATGATCAGGTGAAGGTGTGCACACTGGAGGACATGGAGTTGCTGATACCCACCGTGCTGACGCCAGAGGATTTTACGCATCCACAACTGGATGCGGATCAGTTGCGTGATATTGAGCAACAATTGGCGAACGCGCTGCCCGTCCCACAGTCCAATTTAGCTGGCATACCAGCTGAGCCGACGATAAATGCTGGCAGTAGCGCCAATGTTAGCATCGGTGCCGAGTTTCTGGTCATGCCCGATGGCTCTTTGCAGCAAGTAAATGATGCCGGTGTGGTTTTCGAATACATTGATGATAGCAAAAACACCAATACGACAACCAATATGACATTGCAGAGTCTATTGGGTGATTCCAAGACAGATTTAACCTATAATTCCATGGATATCGATCTGAGTCATATGGTTGTCGACAATACGCTGCCACAGATAACAGttaagCCAAAACCGCGCCCGGCACCTGCGTCTACTGGTGCCCTGAAACACAAATGCAAACTGTGCCCCAAGGCATTTCCAACGGTGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCGAAATTCTATTGTGATCAGTGCTCCTATTATTCGCTGCGTAGCGCCGATCTCATCCAGCACTATACGACAGAGCACAAGTCTTGCATTAGCGAGAGTCGTTCGAATCATTTGGAAAAGGCGCAACTCACCGAGCCGGCGGACAGAAGTCGCATCTATTCATGCGATATGTGTTTGTTTGAGGCACCCAGCAGTGGGCAGTTACGTGTACACTATAGCGACAAGCATCAGATAGTTCCCAGTGAGGTACAGCTGCGCCCCAACTGGGCGTATGAGTCAAAGGATAGGAATTCCAGCTCAACGCGAACCAGTGGCAATAGTACTACAAATCAGCTAGATATTCCACTGGGTATCAAATATCCACCAATGACTTctgcgacagcaacagcgacaagtgCGCTAACAGGTACCAttcagcagccgccgcaggcaacaacaacaactgtggtTACGCAAAGTGGTGACATTAATGTTGTGGTGGATGCCACATCATTGTTCTATGCAGCGGGACAGTTACCAGCAGCTGGTGCTCCAAGAACAGCAGCTACAGATTCAGAAACATTTGCAATATTCCCAGAGCAATCTTTTGCCAACAGCTTGACAACGTCAACAATAACGGGGGAGCCAAACGGTGTGGCACCTGCCACGGTCACTTCAAATCCAAACTCCAGCATATTTGGTGATATGCAGGATTTTATAGATAACACTGATGTGGCGGCCATATGCACCATACCCGCCGATGATATGCCAGTGGTCGACGGCGATGATATTGTTattgataacaataatataagcCTGGATTTTGATGCAGAAAACTTATTCGAAGACTTTGAGGATGTGGAAGTGGGCGAAgaggatgacgatgatgaggatgatgcCGAAAATGATGATGAGAATGATAACAATGATGCGGCAGCCGATCAAAATCTGTTGCTCACCAGCGATGATGACGATGTGGATGACTTTGATGACGAACAATCGAAGCATTTGCAGAAACCATATTGCATCTATTGTAATAAAAAGTTTACCAGCCAATATAAGTTCGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCCTATCGCTGTGAACTGTGCACCAATCTATACAATATGAAACGCCTACTCATACGGCATTATAAGACGGTGCACAAACGCATGCCCACTCGGGACATGGTGCAAGCTAAGGGCGACAAGGTGTCCGTGCCGCGTACAACTATTGAAAAGATAAATGTTTATGTTGACAAACCACCTATGCTAATGTGTGCCAAGTGTCCCTTTGAATGCGAGGAGGAGGGTGAGATGCGTAAGCATCTAAATGCACATCATGGCATCAACGATGGCGTCTCTGTGCACGCCAACGAGGTGTTCATCATACGCAAACTGCCCTATGACTGTCCACGCTGCATTCGCTCATTTGCGGCCAAGCGCACGCTGACACGACATTTGCAACGTAGCCATTTAGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGCTCGGCGGCCACAACGACCACACCAACGGCTACAACCACATTGCCGTTAAACGCTAGTGATggcaataaaacaacaacaacaacaacaacaacaacaaaggcacaACAGGCTTCCAACATGTTGGCGCAGCATGACGCTGGCAATGTCGATGTCGACgtcgatggcgatggcgatggcgatggcgatggaaAATGCGACAGGGACACAGGATTCAAAACGGAAATATTAGACACAGATTTAAAAATCgaagcaacaactacaatggCAACACAAGaaacaaatgcagcaacaactgaaacgacagcagcagaaacagaagTTGCAACAATAGCAAAGACAGAAGCCAcagaagctgcagcaacaaatactAAAGCAATATCAACGACAAcatcaggagcagcagcagcatcaacaaaaacaactgcagGCTCAACACTCTTTCCAACGCCCACGCCATTTGACTATGATTTTGACTTTATTGGCAGTGGTgcacatgccacgcccattaagaacaacagcgacaacttCAACATTGCACCCAGCCCCAGTCATCTATTGAATGGCAGCGACAAGCTACTGACCGCTGCGTTGGAGCCATCGCCAATTAAAGATTTACGTTCTCGCTTACCGCGCACACCCATATTTGTGTGCAAGCAATGCAATCAGACCTTTGATGAGCTTGGCAAGCTGTTGCAGCACGAATTGGAGCAACATTCCAGCAGCATTGTATCGCCGCGCGTCAGTCACCAGCATCAGTGCAAGATCTGTAAAACGACGTACCGCACCATAACGCTACTAAATTACCATATGAAACGGCATACGCCGGCCAAAGTACCATGCCAGCAATGCCCCAAGGAGTTTTTGAATAGCTCAGATTTGGATCAGCACATACAGTCAGATCATAGCGCTAATACAACGACACCACTCAAATGTGGCATAGATGGTTGCAAGAAGACATTTAACTACAAACATCATTTGAAACGGCATCAGACAGCCTCTCATACGCCGGTGCACTATATCTGTCCGGAGTGTGGACGCGACATGCTGACTAGTCTGCATCTGAGGAATCACATGTCAATCCACAAGGGCACACATTCATACAAGTGTCCCAAATGCGTTCGCACCTATATGCGACGCAAACCatTTCGAAGACATGCTTTACGTGAGCACAAATGGGAGCTGACTGAGGAGGAAATAGACAAAATATATAGCATAAATGATACACCACCATCAATCAAATTGCGCCAACGACGATCAGCGAAGGATGAGAACGAGAACTCTGATTAA
Protein Sequence: MAHKRLKTEDMEVNYKFACRCCLKSEAEFFKLDSLIECGISEHDASSTKIPLIRLLLFCMRTENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKTTTRSNGQHASQWLEQTNARDDASLPRQWELKPQKPAVRHECKVCGAIVYNRMELKQHIRMHTESSQHQCKLCNFVTLKHRQLPEHYRKAHGLTAAQIEQQIKIRRSMQAAATTAAITTATETPADDDQVKVCTLEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLANALPVPQSNLAGIPAEPTINAGSSANVSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNTNTTTNMTLQSLLGDSKTDLTYNSMDIDLSHMVVDNTLPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCISESRSNHLEKAQLTEPADRSRIYSCDMCLFEAPSSGQLRVHYSDKHQIVPSEVQLRPNWAYESKDRNSSSTRTSGNSTTNQLDIPLGIKYPPMTSATATATSALTGTIQQPPQATTTTVVTQSGDINVVVDATSLFYAAGQLPAAGAPRTAATDSETFAIFPEQSFANSLTTSTITGEPNGVAPATVTSNPNSSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVPRTTIEKINVYVDKPPMLMCAKCPFECEEEGEMRKHLNAHHGINDGVSVHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTPTATTTLPLNASDGNKTTTTTTTTTKAQQASNMLAQHDAGNVDVDVDGDGDGDGDGKCDRDTGFKTEILDTDLKIEATTTMATQETNAATTETTAAETEVATIAKTEATEAAATNTKAISTTTSGAAAASTKTTAGSTLFPTPTPFDYDFDFIGSGAHATPIKNNSDNFNIAPSPSHLLNGSDKLLTAALEPSPIKDLRSRLPRTPIFVCKQCNQTFDELGKLLQHELEQHSSSIVSPRVSHQHQCKICKTTYRTITLLNYHMKRHTPAKVPCQQCPKEFLNSSDLDQHIQSDHSANTTTPLKCGIDGCKKTFNYKHHLKRHQTASHTPVHYICPECGRDMLTSLHLRNHMSIHKGTHSYKCPKCVRTYMRRKPFRRHALREHKWELTEEEIDKIYSINDTPPSIKLRQRRSAKDENENSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00534822;
90% Identity: iTF_00526843;
80% Identity: -