Basic Information

Insect: Drosophila ezoana
Gene Symbol: -
Assembly: GCA_035045725.1
Location: JAWNOU010000076.1:3103091-3108511[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.004 0.28 11.9 0.7 1 23 147 169 147 169 0.97

2 14 0.00015 0.01 16.4 1.3 1 23 394 416 394 416 0.98

3 14 1.7 1.2e+02 3.6 0.8 1 23 422 445 422 445 0.94

4 14 1.3 91 4.0 0.2 1 23 472 495 472 495 0.92

5 14 0.0013 0.091 13.4 1.9 3 23 754 774 753 774 0.92

6 14 0.051 3.7 8.4 1.4 1 23 780 803 780 803 0.98

7 14 0.35 25 5.8 1.5 2 23 840 861 839 862 0.92

8 14 0.0089 0.63 10.8 0.8 1 23 883 906 883 906 0.97

9 14 0.041 2.9 8.7 1.1 1 23 1130 1153 1130 1153 0.91

10 14 0.0007 0.05 14.2 4.7 1 23 1166 1188 1166 1188 0.98

11 14 0.02 1.4 9.6 0.1 2 23 1194 1216 1193 1216 0.96

12 14 0.0007 0.05 14.2 3.3 2 23 1225 1249 1224 1249 0.90

13 14 0.029 2.1 9.2 0.5 1 23 1254 1276 1254 1276 0.97

14 14 0.0056 0.4 11.4 1.6 1 23 1282 1305 1282 1305 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.004	0.28	11.9	0.7	1	23	147	169	147	169	0.97
2	14	0.00015	0.01	16.4	1.3	1	23	394	416	394	416	0.98
3	14	1.7	1.2e+02	3.6	0.8	1	23	422	445	422	445	0.94
4	14	1.3	91	4.0	0.2	1	23	472	495	472	495	0.92
5	14	0.0013	0.091	13.4	1.9	3	23	754	774	753	774	0.92
6	14	0.051	3.7	8.4	1.4	1	23	780	803	780	803	0.98
7	14	0.35	25	5.8	1.5	2	23	840	861	839	862	0.92
8	14	0.0089	0.63	10.8	0.8	1	23	883	906	883	906	0.97
9	14	0.041	2.9	8.7	1.1	1	23	1130	1153	1130	1153	0.91
10	14	0.0007	0.05	14.2	4.7	1	23	1166	1188	1166	1188	0.98
11	14	0.02	1.4	9.6	0.1	2	23	1194	1216	1193	1216	0.96
12	14	0.0007	0.05	14.2	3.3	2	23	1225	1249	1224	1249	0.90
13	14	0.029	2.1	9.2	0.5	1	23	1254	1276	1254	1276	0.97
14	14	0.0056	0.4	11.4	1.6	1	23	1282	1305	1282	1305	0.96

Sequence Information

Coding Sequence: ATGGCGCACAAACGAGTGAAAACAGAGGACATGGAAGTGAATTACAAATTTGCGTGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTTAAGCTGGACTCACTAATCGAGTGTGGCATAAGCGAGCATGACGCGTCCTCTACTAAAATACCGCTTATACGATTACTATTATTCTGCATGCGCACTGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTCGAATGTAGTAAAAGTTTGCAAATCGCCTACTATTTCATACAGAACGGCTTGCGCGCACATGAAATACTCTGTCGCAAGCTGTGCCCTGGGAAGCTAAAGACGACAACAACTCGTCCGAACGGACAACATACATTGCTATGGCCCGAGCCAAATGCCACAGATGACGCGTCGCTGCCCAGGCACTGGGAGCAGAAACCCCAAAAGTCCACTGTACGACACGAATGCAAAGTATGCGGTGCGATTATGTACAATCGCATGGAGCTCAAACAGCACATACGCATGCACACAGagtcaTCGCGACATCAGTGCAAATTGTGCACCTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCACACGGCTTGACAGCTGCCCAAATTGAGCAACAGATCAAAATCAGAAGATCAATGCAGGCggctgcaacaactgcagctacAACAACCGCAATAGAAACTCCTGCAGACGATGGTCAGGTGAAGGTGTGCACACTGGAGGACATGGAGCTGCTGATACCCACTGTGCTGACGCCAGAGGATTTTACGCATCCACAACTGGATGCGGATCAGTTGCGTGATATTGAGCAACAACTGGCGAACGCGCTGCCCGTCCCACAGTCCAATTTAGCTGGCTTACCAGCTGAGCCGACGATAGATGCTGGAAGTAGCGCCAATGTTAGCATCGGTGCCGAGTTTCTGGTCATGCCCGATGGCTCCTTGCAGCAAGTAAATGATGCCGGTGTGGTTTTCGAATACATTGATGATAGCAAAAATACCAATGCGACAACCAATATGACATTGCAGAGTCTATTGGGCGATTCCAAGACAGATTTATCCTATAATGCCATGGATATCGATCTGAGTCATATGGTTGTCGACAATGAGCTTCCACAGATAAcagttaagCCAAAACCGCGACCGGCGCCTGCGTCTACTGGTGCCCTGAAACACAAATGCAAACTGTGCCCCAAGGCATTTCCAACGGTGGCACGCCTGAAATCTCATCAATTAACGCATAGTCATTTGCCGAAATTCTATTGTGATCAGTGCTCCTATTATTCGCTGCGTAGCGCCGATCTCATTCAGCACTATACGACAGAGCACAAGTCTTGCATAAGCGAGAGTCGTTCGAATCATTTGGATAAGGCGCAACTCACTGAGCCGGCGGACAGAAGTCGCATATATTCATGCGATATGTGTTTGTTTGAGGCACCTAGCAGTGGCCAGTTACGTGTACACTATAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAGCTGCGCCCCAACTGGGCGTATGAGTCAAAGGATAGGAACGCCAGCTCAACGCTTACCAGTGGTAATAGTACGGCAACTCAGCTAGATATTCCACTGGGTATCAAATATCCACCCATGACGTctgcgacagcaacagcgacaagtGCGCCAACAGCTACCAtacagcagccgccgcaggcaacaacaacaactgtggtTACGCAAAGTGGTGACATTAATGTTGTGGTGGATGCCACATCATTGTTCTATGCAGCGGGCCAGTTACCAGCGGCCGGTGctccaacaacagcagctacagaTTCAGGAACATTTGCAATATTCCCAGAGCAATCTTTTGCCAACAGCTTGACAACGTCAACAATAACGGGGGAGCCAAACGGTGTGGCACCTGCCACGGTCACTTCAAATCCAAGCACTAGCATATTTGGCGATATGCAGGACTTTATAGATAACACTGATGTGGCGGCCATATGCACCATACCCGCCGATGATATGCCAGTTGTCGACGGCGATGATATTGTTAttgataacaataatataagcCTGGATTTTGATGCAGAAAACTTATTCGAAGACTTTGAGGATGTGGAAGTGGGTGAAgaggatgacgatgatgaggatgatgcCGAAAATGATGATGAAAATGATAACAATGATGCGGCAGCCGATCAAAATCTTTTGCTCACCAGCGATGATGACGATGTGGATGACTTTGATGACGAACAATCGAAGCATTTGCAGAAACCATATTGCATCTATTGTAATAAAAAGTTTACCAGCCAATATAAGTTCGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCCTATCGCTGTGAACTGTGCACTAATCTGTACAATATGAAACGCCTACTCATACGGCATTATAAGACGGTGCACAAACGCATGCCCACACGGGACATGGTGCAAGCTAAGGGCGACAAGGTGTCCGTGCCGCGTACAACCATTGAAAAGATAAACGTTTATGTTGACAAAACACCCACGCTTATGTGTGCCAAGTGTCCCTTTGAATGCGAACAGGAGGGTGAAATGCGTAAGCATCTAAATGCACATCATGGCATCAACGATGGCGTTTCTGTGCATGCCAACGAGGTGTTTATCATACGCAAACTGCCCTATGACTGTCCACGCTGCATTCGCTCATTTGCGGCCAAGCGCACGCTGACGCGACATTTGCAACGTAGCCATTTAGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCGGCGGCCACAACGACCACGCCAACGGCTACAACCACATTGCCGTTGAACGCTAGTGATggcaataaaacaacaacaacaatggcacaACAGGATTCCAACATTTTGGCGCAGCATGACGCTGGCaatgtcgatgtcgatgtcgacgtcgatggcgatggcgatggaaAATGCGACAGGGACATAGGACTCAAAACGGAAATATTAGACACAGATTTAAAAATCGAAGCGACAACTACAATGGcaacacaagaaaaaaattcaGCAACAACTGAAACGACAGCGGCAGAAACAGAAGTTGCAACAATAGCAAAGACAGAAGCCAcagaagctgcagcaacaaatacaacagcaatattaacaacaacatcaggagcagcagcagcatcaacaacaacaactgcaggcTCAACACTCTTTCCAACGCCCACGCCATTTGACTATGATTTTGACTTTATTGGCAGTGGTGCACATGCCACGACCATtaagaacaacaacgacagcttCAACATTGCGCCCAGCCCCAGTCATCTATTGAATGGCAGCGACAAGCTACTGACCGCTGCGTTAGAGCCATCGCCAATAAAAGATTTACGTTCGCGCTTACCGCGCACACCTATATTTGTGTGCAAGCAATGCAATCACACCTTTGATGAGCTTGGCAAGCTGTTGCAGCACGAGTTGGAGCAACATTCCAGCAGCATTGTGCCGCCGCGCGTCAGTCACCAGCATCAGTGCAAGATTTGTAAAACGACCTACCGCACGGTAACGCTACTAAATTATCATATGAAGCGGCATGCGCCGGCCAAAGTTCAATGCGAACAATGCCCTAAGGAGTTTTTGAATAGCCCAGATTTGGATCAGCACATACAGTCGGATCATAGCGCTAATACAACGACACCACTCAAATGCGGCATAGATGGTTGCGAGAAGACATTTAACTACAAACATCATTTGAAACGGCATCAGACAGCCTCTCATACGCCGGTTCACTATATCTGTCCGGAGTGTGGACGCAACATGTTGACTAGTCTGCATCTGAGGAATCACATGTCAATCCACAAGGGCACACATTCTTACAAGTGTCCCAAATGCGTGCGCACCTATATGCGACGCAAACCcttTCGAAGACATGCTTTACGTGAGCACAAATGGGAGCTGACTGAGGCGGAAATAGACAAAATATATAGCATAAATGATACACCACCATCAATCAAATTGCGGCAACGACGATCAGTGAAGGTTGAGAACGAGAACTCTGATTAA
Protein Sequence: MAHKRVKTEDMEVNYKFACRCCLKSEAEFFKLDSLIECGISEHDASSTKIPLIRLLLFCMRTENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKTTTTRPNGQHTLLWPEPNATDDASLPRHWEQKPQKSTVRHECKVCGAIMYNRMELKQHIRMHTESSRHQCKLCTFVTLKHRQLPEHYRKAHGLTAAQIEQQIKIRRSMQAAATTAATTTAIETPADDGQVKVCTLEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLANALPVPQSNLAGLPAEPTIDAGSSANVSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNTNATTNMTLQSLLGDSKTDLSYNAMDIDLSHMVVDNELPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCISESRSNHLDKAQLTEPADRSRIYSCDMCLFEAPSSGQLRVHYSDKHLIVPSEVQLRPNWAYESKDRNASSTLTSGNSTATQLDIPLGIKYPPMTSATATATSAPTATIQQPPQATTTTVVTQSGDINVVVDATSLFYAAGQLPAAGAPTTAATDSGTFAIFPEQSFANSLTTSTITGEPNGVAPATVTSNPSTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVPRTTIEKINVYVDKTPTLMCAKCPFECEQEGEMRKHLNAHHGINDGVSVHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTPTATTTLPLNASDGNKTTTTMAQQDSNILAQHDAGNVDVDVDVDGDGDGKCDRDIGLKTEILDTDLKIEATTTMATQEKNSATTETTAAETEVATIAKTEATEAAATNTTAILTTTSGAAAASTTTTAGSTLFPTPTPFDYDFDFIGSGAHATTIKNNNDSFNIAPSPSHLLNGSDKLLTAALEPSPIKDLRSRLPRTPIFVCKQCNHTFDELGKLLQHELEQHSSSIVPPRVSHQHQCKICKTTYRTVTLLNYHMKRHAPAKVQCEQCPKEFLNSPDLDQHIQSDHSANTTTPLKCGIDGCEKTFNYKHHLKRHQTASHTPVHYICPECGRNMLTSLHLRNHMSIHKGTHSYKCPKCVRTYMRRKPFRRHALREHKWELTEAEIDKIYSINDTPPSIKLRQRRSVKVENENSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00534822;
90% Identity: iTF_00526843;
80% Identity: -