Dvii001591.1
Basic Information
- Insect
- Drosophila virilis
- Gene Symbol
- -
- Assembly
- GCA_007989325.2
- Location
- CM017608.2:20218502-20223875[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00033 0.019 15.0 0.5 1 23 146 168 146 168 0.98 2 13 0.00012 0.0073 16.4 1.3 1 23 393 415 393 415 0.98 3 13 1.5 87 3.6 0.8 1 23 421 444 421 444 0.94 4 13 0.84 50 4.3 0.2 1 23 471 494 471 494 0.93 5 13 0.0011 0.064 13.4 1.9 3 23 753 773 752 773 0.92 6 13 0.043 2.6 8.4 1.4 1 23 779 802 779 802 0.98 7 13 0.29 17 5.7 1.5 2 23 839 860 838 861 0.92 8 13 0.0075 0.45 10.8 0.8 1 23 882 905 882 905 0.97 9 13 0.014 0.83 9.9 0.4 1 23 1135 1158 1135 1158 0.91 10 13 0.00059 0.035 14.2 4.7 1 23 1171 1193 1171 1193 0.98 11 13 0.00059 0.035 14.2 3.3 2 23 1228 1252 1227 1252 0.90 12 13 0.041 2.4 8.5 0.4 1 23 1257 1279 1257 1279 0.97 13 13 0.0047 0.28 11.4 1.6 1 23 1285 1308 1285 1308 0.96
Sequence Information
- Coding Sequence
- ATGGCGCACAAACGAGTGAAAACAGAGGACATGGAAGTGAATTACAAATTTGCGTGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTTTAAGCTGGACTCACTAATCGAGTGTGGCATAAGCGAGCATGACGCGTCCTCTACTAAAATACCCCTGATACGCTTACTATTATTCTGCATGCGCACTGAAAACCAGCCCGAGCTGCCGCAATACATATGCGTCGAGTGTAGTAAAAGTTTGCAAATTGCCTACTATTTCATACAGAACGGCTTGCGTGCACATGAAATACTCTGTCGCAAGCTGTGCCCTGGGAAGCTAAAGACAACAACTCGTTCGAACGGACAACATGCATCGCTATGGACCGAGACAAATGCCAGAGATGACGCGTCGTTGCCCAGGCTCTGGGAGCAGAAACCTCAAAAGTCCGCTGTACGACACGAATGCAAAGTATGCGGTGCGATTGTGTACAATCGCATGGAGCTCAAACAGCACATACGTATGCACACAGAGTCATCGCAACATCAGTGCAAATTGTGCAACTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCACATGGCTTGACAGCTGCCCAAATTGAGCAACAGATCAAAATCAGACGGTCTATGCAGGCGGCTGCAACAACTTCAACGACAACAAACGCAATAGAAACTCCTGCAGATGATGGTCAGGTGAAGGTGTGCACACTGGAGGACATGGAGCTGCTGATACCCACTGTGCTGACGCCAGAGGATTTTACGCATCCACAACTGGATGCGGATCAGTTGCGTGATATTGAGCAACAATTGGCGAACGCGCTGCCCGTCCCACAGTCCAATTTAGCTGACATACCAGCTGATCCGACGATAGATGCTGGCGTTAGCGCCAATGTTAGCATCGGTGCCGAGTTTCTGGTCATGCCCGATGGCTCTTTGCAGCAAGTAAATGATGCCGGTGTGGTTTTCGAATACATTGATGATAGCAAAAACACCAATACGACAACCAATATGACATTGCAAAGTCTTTTGGGCGATTCCAAGACAGATTTATCCTATAATGCCATGGATATCGATCTGAGTCATATGGTTGTCGACAATGCGCTGCCACAGATAACAGttaagCCAAAACCGCGCCCGGCACCTGCGTCTACTGGTGCCCTGAAACACAAATGCAAACTGTGCCCCAAGGCGTTTCCAACAGTGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCGAAATTCTATTGTGATCAGTGCTCCTATTATTCGCTGCGTAGCGCCGATCTCATCCAGCACTATACGACAGAGCACAAGTCTTGCATTAGCGAGAGTCGCTCGAATCATTTGGATAAGGCGCTGCTCACTGAGCCGGCGGACAGAAGTCGCATATATTCATGCGATATGTGTTTGTTTGAGGCACCCAGCAGTGGGCAGTTACGTGTACACTATAGCGAAAAGCATCTGATAGTGCCCAGTGAGGTACAGCTGCGCCCCAACTGGACGTATGAGTCAAAGGATAGGAACGCTAACTCAACGTTAACCAGTGGCCATAGTACTGCAACCCAGTTAGATATTCCGCTGGGTATCAAATATCCACCCATGACGTCTGCGACAGGAACAGCGACAAGTTCGCCAACAGCTACCatacagcagccgccgcaggcaacaacaacaactgtggtTACGCAAAGTGGCGACATTAATGTTGTGGTGGATGCCACATCATTGTTCTATGCCGCGGGCCAGTTACCAGCAGCTGGTGCTCCAACAACAGGAGCTACAGATTCAGAaacatttgcaatatttccAGAGCAATCTTTTGCCAACAGCTTGACAACGTCAACTATAACGGGGGAGACAAACGGTGTGGCACCTGCCACGGTTAGTTCAAATCCAAACACCAGCATATTTGGCGATATGCAGGATTTTATAGATAACACTGATGTGGCGGCCATATGCACCATACCCGCCGATGATATGCCAGTGGTCGACGGCGATGATATTGTTAttgataacaataatataagcCTGGATTTTGATGCTGAAAACTTATTCGAAGACTTTGAGGATGTGGAAGTGGGCGAAgaggatgacgatgatgaggaTGATGCCGAAAATGATGATGAGAATGATAACAATGATGCGGCAGCCGATCAAAATCTGTTGCTAACCAGCGATGATGACGATGTGGATGACTTTGATGACGAACAATCGAAGCATTTGCAGAAACCATATTGCATCTATTGTAATAAAAAGTTTACCAGCCAATATAAGTTCGAGAATCATATGTTTGTGCATCGCGGTTTGGCACCATATCGCTGTGAACTATGCACTAATCTGTACAATATGAAACGCCTACTCATACGGCATTATAAGACGGTGCACAAACGCATGCCCACTCGGGACATGGTGCAAGCTAAGGGCGACAAGGTGTCCGTACCGCGAACAACCATTGAAAAGATAAGCGTCTATGTTGACAAACCACCTACGCTAATGTGTGCCAAGTGTCCCTTTGAGTGCGAACAGGAGGGTGAAATGCGTAAGCATCTAAATGCACATCATGGCATCAACGATGGTGTTTCTTTGCATGCCAACGAGGTGTTTATCATACGCAAACTGCCCTATGACTGTCCACGCTGCATTCGCTCATTTGCGGCCAAGCGCACGCTGACACGACATTTGCAACGTAGCCATTTAGTGGACACAATCATTGAGATGCAGGCACCTCAATTGACAACTAGTTCGGCATCCACAACAACCACACCAACGGCTACAACCACATTGCCGTTGAACGCTAGTGATggtaataaaacaacaacaacaacaacaatggcacaaCAGGATTCCAGCATGTTGGCGCAGCATGACGCTGGCAATATCGATGTCGACgtcgatggcgatggcgatggcgatggcgatggaaAATGCGACAGGGACATTGGATTCAAAACGGAAATATTAGACACAGATTTAAAAGTCGAAGCGACAACTACAATGGCAtcacaagaaaaaaatgcagcaacaactgaaacGACATCAGCAGAAACAGAAGTTGCAACAAGAGCAAAGACAGAAGACACAGAAGATGCAGCAACAAATACTAAAGCAATATCAACGACAACatcaggagcaggagcagcatcgaaaacaaccacaacaactgcAGGCTCAACACTCTTTCCAACGCCCACGCCATTTGACTATGATTTTGACTTTATTGGCAGTGGTGCAAATGCCACGTCCAATAagagcaacaacgacagcttCAACATTGCACCCAGCCCCAGTCATCTTTTGAATGGCAGCGACAAGCTACTGACCGCTGCGCTGGAGCCATCGCCAATTAAAGATTTACGTTCGCGATTACCGCGCACACCCATATTTGTGTGCAAGCAATGCAATCAGACCTTCGATGAGCTTGGCAAGCTGTTGCAGCACGAATTGGAGCAACATTCCAGCAGCATTGTATCGCCGCGCGTCAGTCACCAGCATCAGTGTAAGATATGTAAAACGACCTACCGCACCGTAACGCTACTAAATTACCATATGAAACGGCATGCGCCGGCCAAAGTTCCATGCCAACAATGCCCCAAAGAGAATAGCCCAGATTTGGATCAGCACATACAGTCAGATCATAGCGCTAATACAACGACACCACTGAAATGCGGTGTAGATGGTTGCGAGAAGACATTTAACTACAAACATCATTTGAAACGACATCAGACAGCCTCTCATACGCCGGTGCACTATATCTGTCCGGAATGTGGACGCGACATGTTAACTAGTCTGCATCTAAGGAATCACATGTCAATCCACAAAGGCACACATTCTTACAAGTGTCCCAAATGCGTTCGCACCTATATGCGACGCAAACCttttcgaAGACATGCTTTACGTGAGCACAAATGGGAGCTGACTGAGGAGGAAATAGACAAAATATATAGCATTAACGATACACCACCATCAATCAAATTGCGCCAACGACGATCAGCGAAGATTGAGAACGAGAACTCTGATTAA
- Protein Sequence
- MAHKRVKTEDMEVNYKFACRCCLKSEAEFFKLDSLIECGISEHDASSTKIPLIRLLLFCMRTENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKTTTRSNGQHASLWTETNARDDASLPRLWEQKPQKSAVRHECKVCGAIVYNRMELKQHIRMHTESSQHQCKLCNFVTLKHRQLPEHYRKAHGLTAAQIEQQIKIRRSMQAAATTSTTTNAIETPADDGQVKVCTLEDMELLIPTVLTPEDFTHPQLDADQLRDIEQQLANALPVPQSNLADIPADPTIDAGVSANVSIGAEFLVMPDGSLQQVNDAGVVFEYIDDSKNTNTTTNMTLQSLLGDSKTDLSYNAMDIDLSHMVVDNALPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCISESRSNHLDKALLTEPADRSRIYSCDMCLFEAPSSGQLRVHYSEKHLIVPSEVQLRPNWTYESKDRNANSTLTSGHSTATQLDIPLGIKYPPMTSATGTATSSPTATIQQPPQATTTTVVTQSGDINVVVDATSLFYAAGQLPAAGAPTTGATDSETFAIFPEQSFANSLTTSTITGETNGVAPATVSSNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVPRTTIEKISVYVDKPPTLMCAKCPFECEQEGEMRKHLNAHHGINDGVSLHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSASTTTTPTATTTLPLNASDGNKTTTTTTMAQQDSSMLAQHDAGNIDVDVDGDGDGDGDGKCDRDIGFKTEILDTDLKVEATTTMASQEKNAATTETTSAETEVATRAKTEDTEDAATNTKAISTTTSGAGAASKTTTTTAGSTLFPTPTPFDYDFDFIGSGANATSNKSNNDSFNIAPSPSHLLNGSDKLLTAALEPSPIKDLRSRLPRTPIFVCKQCNQTFDELGKLLQHELEQHSSSIVSPRVSHQHQCKICKTTYRTVTLLNYHMKRHAPAKVPCQQCPKENSPDLDQHIQSDHSANTTTPLKCGVDGCEKTFNYKHHLKRHQTASHTPVHYICPECGRDMLTSLHLRNHMSIHKGTHSYKCPKCVRTYMRRKPFRRHALREHKWELTEEEIDKIYSINDTPPSIKLRQRRSAKIENENSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00534822;
- 90% Identity
- iTF_00526843;
- 80% Identity
- -