Dins008396.1
Basic Information
- Insect
- Drosophila insularis
- Gene Symbol
- -
- Assembly
- GCA_018903935.1
- Location
- JAEIFP010002295.1:13487259-13490356[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.29 23 5.8 1.1 1 23 160 183 160 183 0.95 2 14 0.0005 0.04 14.4 3.3 1 23 236 259 236 259 0.96 3 14 0.0049 0.38 11.3 0.6 2 23 313 334 312 334 0.97 4 14 4.8 3.8e+02 1.9 1.5 1 20 452 471 452 473 0.87 5 14 0.0068 0.54 10.9 1.2 1 23 482 504 482 504 0.95 6 14 8.7e-05 0.0069 16.8 1.1 1 23 511 534 511 534 0.96 7 14 0.00026 0.021 15.3 1.0 3 23 544 564 542 564 0.96 8 14 0.0037 0.29 11.7 0.0 2 22 591 611 590 614 0.90 9 14 0.0035 0.28 11.8 1.1 1 23 650 673 650 673 0.96 10 14 0.0047 0.37 11.4 1.8 1 23 710 733 710 733 0.95 11 14 1.3e-05 0.001 19.4 0.5 1 23 758 781 758 781 0.97 12 14 0.078 6.1 7.5 0.2 1 23 791 813 791 813 0.94 13 14 5.2e-05 0.0041 17.5 3.7 1 23 819 841 819 841 0.99 14 14 6.6e-06 0.00052 20.4 3.6 1 23 847 869 847 869 0.98
Sequence Information
- Coding Sequence
- ATGACAAAGATTTGCCGAGTCTGCGCTGGCCCTGATGGACGATTTTGGATGGAGGCTCCTGTGGGCAATGAGAAATATGCAGGAAAAACGTTCAGTCAATTGCTATTCGATTTGACCAAAATTGAGGTTACCGCTGTCCAGATGGAGAAGTTAACGTCCTGGATATGCCGCAATTGTGCCCATAAATTGCAGCATTCCCACGATTTTGTGTCCAAGGCCAAGAGAACACATGAAATGTGGTTGGGAAAAATGGCCGATGATCCTATCTGTTTACGTGAGACTCCCATACATTTAATGGAGATTGAAGGGGTTACCATTAAAATGGAAGATGTCGAACCAACTGTACCTACTGCAATTCCATCCTCTGTTCCCGATCCTCTACAAACGGTACATAATACCGACCAGGAGATTAAAAAAACTGTAAGGAAACTGGCGATAAATCGAGAGGAAATAACTGAAAACGAGGATGACAACTATTATAAATGTGATCAGTGTGAGAACTCCTACAAGTATGTCATGCTTATGGTCCAGCATAAGCAAAAGGTTCATGGAGTCCATCAAATGCCCTCGAGTCGAGGGCAAGGGGCATCGACAACTGCAGCCACTCAGCAGAGGGCCAAACTGAATACTGACTTGTTGGTGCATAGTCTTATCAAAACAGTGGAAATCTCGGATGAAGATGGCAGTTCCAGTTCTGATAATTACTACAAATGCGATCAATGTGACAAATCCTATAAATACATTGTTAGTCTAATCAAGCACAAGCATAAGGAACATACAGAAAACTCCAGGGATTCGGACGATGGCGATGATCAAATCCAGGCATCCACATCCAACTCTGCTAGCATGAATGTTTCTTTAAAGACTTCTCGTATCAATCGACGTGTTCAGGATTTCGACCCCCTTCGTTGTCAACCGAATGGCTCCAAGGAAATTAAATGCATGATCTGTTTACGTCGTTTTGCCAAACTGGGTGAACTGCGCTATCATCTAAAATACCACCCAGAAGACTTTGATTTTGAGGCTCACGGCGAGCCTATTGAACGTATAGCTGAGGGCTTCTTCAAGACAGCTGTTGAATCGACATCGGAGGGTCTTAAGCGACGCATTTTTAAGGATCTGAACATGGGATTATATGGTCGTTACTACTCTATTACCAATGAGGCACGCTACGAGTTGAGTCTAGATAGCTCCGATACGGATAGCGATGGAGGTGACGCCGATGCCCAGGTGATCATACGGCGCAGTTATGCATGTGAATTGTGTAATACCTCTAACCAGACGGCTGTATGGCCTCGCAAGTATCAGCTTCATGAGCATCATAGGCAATGTCACACATGGCTGGAGGCTCCCCATGTCTGTCAGCGCTGCGACTCGCGCTTCTTGAGCGAAAAACTTCTAGAACATCATACTAGTCAGCTATGTAATAATACTTTAAAACGATTTCAATGCGACAAATGTCCACAGCGTTTCTTTTGGCGTAAGAATTTGCGTTCGCACTTGGCGGATCATAAAGATAAGCAAGAAAATTATCCCTGCGATCAATGTCAGCGTAGTTTTCAGGACAAAAGTTCTGTGACGAGGCATAAATTAATGATGCATGCAGATGGAAAGAGTCAACTTATAGCTTGCCGTTGGTGCACTCGGGTTTTCTACCGCCCAGCACTCCTTCATAAGCATCTACAACGCCATGGCTTCAGTGGGCAAGATTTACCCCTGGCCGAGACATTGTTGGCTGATGCAGCAAAACCTTTAGGGCCAAAGAACATTCAATGCAAACTCTGTGATATTAAATTTGTTAGCATTGCGGACTTGCGTGGTCACATGGCCATGTTGGAACACGGAAATCAGATTTCCAGTTATATGATCAGTACTGAAGCTGGATTTGAATTGCAACTGGATGATACAGATGATAGCGACGATGATGATGGCCATACAAAGAGCTCCTACACATGTGATCTCTGCCAAATGAAATTCCCACGCAGACGTGAAATGAGTGAACATCAATACTCGTTACATACGTTTGATAAACTGCCACACGCATGCGATCAGTGTATATATAAAACTGTCAATAAGCTCATGTTGAAGCATCATGAACTGACTCAATGCCAAAACAAAGAGAAGAAGTTTATTTGCACGCATTGCGGTTATCGATTTATGTGGCAAGAGAATCTCGACAAGCACCTGTCCAGTCAGCATCCAAAACAAAAAACAAGCAGCTATGATCAACAATTGCCAAGTTCTTCCATTCGTCGAAAAAGACGCTTCAGATACCAATGTCCGCACTGTTGGCGCTCTTTTGTTGTTCAGCCCAGCTTGGATAAGCACATTAGAGACATGCATGTGGCTAAAAAGAATCCAGGCAAGAAATATCTGTGTTCGCTCTGCGGCCTGGAATCGCTTACTCCCAATAAATTAAGTATTCATATGCGACGCCACATGGGAGAGAAACCTTTCAAATGTGATCTCTGTGATATGCGTTTCACGGTTCATTATGAACTTAAAGTGCACAGAAGAAAACACACAGGCGAACGTCCTTATAAATGTACTTTCTGTGACAAACATTTCGCTCGGCCCGATAAACTGAGACGTCATGTCTATATGCACAGCGATAAGCGTTAG
- Protein Sequence
- MTKICRVCAGPDGRFWMEAPVGNEKYAGKTFSQLLFDLTKIEVTAVQMEKLTSWICRNCAHKLQHSHDFVSKAKRTHEMWLGKMADDPICLRETPIHLMEIEGVTIKMEDVEPTVPTAIPSSVPDPLQTVHNTDQEIKKTVRKLAINREEITENEDDNYYKCDQCENSYKYVMLMVQHKQKVHGVHQMPSSRGQGASTTAATQQRAKLNTDLLVHSLIKTVEISDEDGSSSSDNYYKCDQCDKSYKYIVSLIKHKHKEHTENSRDSDDGDDQIQASTSNSASMNVSLKTSRINRRVQDFDPLRCQPNGSKEIKCMICLRRFAKLGELRYHLKYHPEDFDFEAHGEPIERIAEGFFKTAVESTSEGLKRRIFKDLNMGLYGRYYSITNEARYELSLDSSDTDSDGGDADAQVIIRRSYACELCNTSNQTAVWPRKYQLHEHHRQCHTWLEAPHVCQRCDSRFLSEKLLEHHTSQLCNNTLKRFQCDKCPQRFFWRKNLRSHLADHKDKQENYPCDQCQRSFQDKSSVTRHKLMMHADGKSQLIACRWCTRVFYRPALLHKHLQRHGFSGQDLPLAETLLADAAKPLGPKNIQCKLCDIKFVSIADLRGHMAMLEHGNQISSYMISTEAGFELQLDDTDDSDDDDGHTKSSYTCDLCQMKFPRRREMSEHQYSLHTFDKLPHACDQCIYKTVNKLMLKHHELTQCQNKEKKFICTHCGYRFMWQENLDKHLSSQHPKQKTSSYDQQLPSSSIRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYKCTFCDKHFARPDKLRRHVYMHSDKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00604270; iTF_00555267; iTF_00503444; iTF_00571336; iTF_00612249; iTF_00618587;
- 90% Identity
- -
- 80% Identity
- -