Dtro007246.1
Basic Information
- Insect
- Drosophila tropicalis
- Gene Symbol
- -
- Assembly
- GCA_018151085.1
- Location
- JAECWH010000848.1:2062819-2065893[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 0.0003 0.023 15.2 5.1 1 23 183 206 183 206 0.97 2 16 0.013 0.98 10.1 0.9 1 23 235 258 235 258 0.97 3 16 0.00057 0.044 14.3 3.3 1 23 307 330 307 330 0.96 4 16 0.0055 0.42 11.2 0.6 2 23 384 405 383 405 0.97 5 16 4.8 3.7e+02 1.9 0.7 1 19 523 541 523 543 0.75 6 16 0.0099 0.76 10.4 1.2 1 23 553 575 553 575 0.94 7 16 9.8e-05 0.0076 16.7 1.1 1 23 582 605 582 605 0.96 8 16 0.0003 0.023 15.2 1.0 3 23 615 635 613 635 0.96 9 16 0.0039 0.3 11.7 0.0 2 22 662 682 661 685 0.90 10 16 0.004 0.31 11.6 1.1 1 23 721 744 721 744 0.96 11 16 3.7 2.9e+02 2.3 2.1 1 22 751 772 751 772 0.94 12 16 0.0052 0.4 11.3 1.8 1 23 781 804 781 804 0.95 13 16 1.4e-05 0.0011 19.3 0.5 1 23 829 852 829 852 0.97 14 16 0.087 6.8 7.4 0.2 1 23 862 884 862 884 0.94 15 16 2.2e-05 0.0017 18.7 3.3 1 23 890 912 890 912 0.99 16 16 7.4e-06 0.00057 20.2 3.6 1 23 918 940 918 940 0.98
Sequence Information
- Coding Sequence
- ATGACAAGGATTTGCCGTGTCTGCGCTGGCCCTGATGGGCGATTTTGGATGGAGACTCCTGTTGAGAAATATGCAGGAAAAACTTTCAGTCAATTGCTATTCGACTTGACCAAAATTGAGATTACCGCTGTCCAGATGGAAAAGTTAACGTGCTGGATGTGCCGCAATTGTGCTCATAAATTGCAGCATTCCTATGATTTTGTCTCCAAGGCTAAGAGAACACACGAGAAGTGGTTGGAAAAAATTGCCGATGATCCTGTCTGTTTACGTGAGACTCCCATTAATTTAATGGAGATCGAAGGGGTAACCATTAAAATGGAAGATGTGGAACCAACTGTAACTACAGCAGTTCCATGCTCTGTTCCCGATCCTTTAGTTCGTATAGGCGTAGAAAAGGGTTGCATATCTGATTTAAGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGCTAAAGCAGCGATCTGAAAGGACCAAGTCTCAGGCTTTTGCCAATTTGAAGAAACATAAATGTAATAAATGCACTAAAGCCTTTAAATATATCACAAATCTCTACCGGCATAAGCAAACGGTACACAATACCGATAAGGAGATTAAAAAAAGTGTAAGGAAACTAGCAATAAATCGAGAGGATGTAAATGAAAACGACGATGACAACTATTATAAATGCGATCAGTGTGATAACTCCTACAAGTATGTTATGCTTCTAGTCCAGCACAAGCAAAGGGTTCATGGAGTCGACCAAATGCCCTCTAGTCAAAGGCAAAGGGCAGCTCCTCAGCAGAGACCCAAGCTGAATACTGACATGCTTGTGCATAGTCTTATCAAAGCAGTGGAAATCTCGGATGAAGATGGCAGTTCCAGTTCGGATAATTACTACAAATGCGATCAATGTGACAAATCCTATAAATACATTGTTAGTCTCATCAAGCACAAGCATAAGGAACACACAGAAAACTCTAGAGATTCGGACAACGGCGATGATCAAATCCAGGCCTCTACATCCAACTCAGCTGGCATTAGTGTTCCTCTAAAGCCTTCTCGTATCAATAGGCGTGTTCAGGACTTTGACCCCCTTCGTTGTCAACCGAATGGTTCTAAGGAGATTAAATGCATGATCTGTTTGCGTCGTTTTGCCAAACTGGGAGAACTGCGCTATCATCTGAAATACCACCCAGACGATTTTGATTTTGAGGCTCATGGCGAGCCTATTGAACGTATAGCTGAAGGTTTTTTTAAGACAGCCGTTGAATCGACAGCGGAGGGTCTAAAGCGACGCATTTTTAAGGATCTTAACATGGGATTATATGGTCGTTACTACTCTATTACCAACGAGGCACGCTATGAGTTGAGTCTAGATAGCTCCGATACAGACAGCGATGGAGGTGATGCCGATGCCCAGGTGATCATCCGGCGTAGTTATGCATGTGAATTGTGTAATACCTCCAACCAACCGGCTGTCTGGCCCCGCAAATATCAACTTCATGAGCATCATAGGCAATGTCACACATGGCTGGAGGCTCCTTATGTCTGTCAGCGTTGCGACTCGCGCTTCTTAAACGGAAAACTTCTAGAACATCATACTAGTCAGCTTTGTAATAATACCTTGAAACGTTATCAATGCGACAAATGTCCACAGCGTTTCTTTTGGCGTAAAAATTTGCGCTCTCACTTAGTGGATCATAAAGATAAGCAAGAAAATTATCCTTGCGACCAATGTCAGCGTAGTTTTCAAGACAAAAGCTCTGTGACTAGGCATAAATTAATGATGCATGCAGATGGAAAGAGCCAACTTATAGCTTGTCGTTGGTGCACTCGGGTTTTCTACCGACCAGCACTGCTTCATAAGCATCTCCAACGCCATGGTTTCAGTGGGCAAGACTTACCCTTGGCTGAAACATTGTTGGCCGACGCAGTCAAGCCCTTGGGGCCAAAGAACATTCAGTGCAAACTCTGTGACCTTAGATTTATTAACATTGCAGACTTGCGTGGTCACATGGCCATGTTGGAGCACGACACTCAGGTTTCCAGTTATATGATCAGTACTGAAGCTGGATTTGAACTGCAACTGGATGATACAGATGATAGCGACGATGATGATGGCCATACAAGAAGATCCTACACATGTGATCTCTGTCAAATGAAATTCCCACGCAGACGTGAAATGAGTGAGCATCAATACTCGTTACATACGTTTGATAAACTGCCACATACATGCGATCAATGTATATATAAAACTGTAAATAAGCTCATGTTAAAGCATCATCAACTAACACAATGCCAAAACAAAGAGAAGAAGTTTATTTGCACGCATTGCGGTTACCGGTTCATGTGGCAAGAGAATCTCGACAAGCACTTGTCCAGCCAGCATCCGAAACAAAAGACAAGCAGCTACGATCAACAGACGCCAAGTTCTTCTATACGTCGAAAAAGACGCTTCAGATACCAATGTCCGCACTGTTGGCGCTCTTTTGTTGTTCAGCCCAGCTTGGATAAGCACATTCGAGACATGCATGTGGCTAAAAAGAATCCGGGCAAAAAATATCTCTGTTCGCTCTGTGGCCTGGAATCCCTTACACCCAATAAATTAAGTATTCATATGCGTCGCCATATGGGCGAAAAACCCTTTAAATGTGATCTCTGTGATATGAGTTTCACGGTTCATTATGAACTGAAAGTGCACAGAAGAAAACACACAGGTGAACGTCCTTATAAATGTACTTTCTGTGACAAACATTTCGCTCGCCCCGATAAACTGAGACGTCATGTCTATATGCACAGCGATAAACGTTAG
- Protein Sequence
- MTRICRVCAGPDGRFWMETPVEKYAGKTFSQLLFDLTKIEITAVQMEKLTCWMCRNCAHKLQHSYDFVSKAKRTHEKWLEKIADDPVCLRETPINLMEIEGVTIKMEDVEPTVTTAVPCSVPDPLVRIGVEKGCISDLSXXXXXXXXXXXXXXXXXXXXXXXXPLKQRSERTKSQAFANLKKHKCNKCTKAFKYITNLYRHKQTVHNTDKEIKKSVRKLAINREDVNENDDDNYYKCDQCDNSYKYVMLLVQHKQRVHGVDQMPSSQRQRAAPQQRPKLNTDMLVHSLIKAVEISDEDGSSSSDNYYKCDQCDKSYKYIVSLIKHKHKEHTENSRDSDNGDDQIQASTSNSAGISVPLKPSRINRRVQDFDPLRCQPNGSKEIKCMICLRRFAKLGELRYHLKYHPDDFDFEAHGEPIERIAEGFFKTAVESTAEGLKRRIFKDLNMGLYGRYYSITNEARYELSLDSSDTDSDGGDADAQVIIRRSYACELCNTSNQPAVWPRKYQLHEHHRQCHTWLEAPYVCQRCDSRFLNGKLLEHHTSQLCNNTLKRYQCDKCPQRFFWRKNLRSHLVDHKDKQENYPCDQCQRSFQDKSSVTRHKLMMHADGKSQLIACRWCTRVFYRPALLHKHLQRHGFSGQDLPLAETLLADAVKPLGPKNIQCKLCDLRFINIADLRGHMAMLEHDTQVSSYMISTEAGFELQLDDTDDSDDDDGHTRRSYTCDLCQMKFPRRREMSEHQYSLHTFDKLPHTCDQCIYKTVNKLMLKHHQLTQCQNKEKKFICTHCGYRFMWQENLDKHLSSQHPKQKTSSYDQQTPSSSIRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHMGEKPFKCDLCDMSFTVHYELKVHRRKHTGERPYKCTFCDKHFARPDKLRRHVYMHSDKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00523880;
- 90% Identity
- iTF_00571336;
- 80% Identity
- -