Dsuc000408.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila sucinea
Gene Symbol
-
Assembly
GCA_018150745.1
Location
JAECWP010000114.1:489326-492457[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00059 0.044 14.3 2.6 2 23 130 152 129 152 0.96
2 16 0.0003 0.022 15.2 2.0 1 23 182 205 182 205 0.97
3 16 0.0018 0.13 12.8 3.3 1 23 255 278 255 278 0.96
4 16 0.0054 0.4 11.3 0.5 2 23 332 353 331 353 0.97
5 16 1.8 1.3e+02 3.3 0.7 1 19 471 489 471 491 0.76
6 16 0.013 1 10.0 1.3 1 23 501 523 501 523 0.94
7 16 9.4e-05 0.007 16.8 1.1 1 23 530 553 530 553 0.96
8 16 0.0013 0.099 13.2 1.6 2 23 562 583 561 583 0.96
9 16 0.00035 0.026 15.0 0.1 2 22 610 630 609 633 0.90
10 16 0.0089 0.66 10.6 0.6 1 23 669 692 669 692 0.95
11 16 3.1 2.3e+02 2.6 2.1 1 22 699 720 699 720 0.94
12 16 0.0055 0.41 11.2 1.6 1 23 729 752 729 752 0.95
13 16 1.4e-05 0.001 19.4 0.5 1 23 777 800 777 800 0.97
14 16 0.084 6.2 7.5 0.2 1 23 810 832 810 832 0.94
15 16 5.6e-05 0.0041 17.5 3.7 1 23 838 860 838 860 0.99
16 16 5.8e-06 0.00043 20.6 3.2 1 23 866 888 866 888 0.98

Sequence Information

Coding Sequence
ATGACAAGAATCTGCCGAGTCTGCGCTGGCCCCGATGGGCGATTTTGGATCGAGACCCCTGTGGAAAATGATAAATATGCAGGGAAAACGTTCAATCAATTGCTGCTCGATCTGACCAAAATAGAGGTTACCCTCACCCAGGTGGAGAAGTTGACGCCCTGGATATGCCGCAATTGTGCGCATAAATTGCAGCATTCCTATGACTTTGTCTTAAAGGCCAAGAGGACACACGAGATGTGGCTGGAAAAAATGACTGATGATCTTTTTTGTCTAAGTGAGACTCCTATACATTTAATGGAGATTGAAGGGGTGACCATAAAAATGGAAGACACGGAGCAAACTGCACCTACACCAGCACCTTGTCCTGTTCCCGATCCTCTCAGGAATAAATGTAATCAATGCTCTAGAACCTTTAGATATGTCACAAATCTCTACAGGCACAAGCAAATGGAACACACAGTCGAAAAGGAGATTAAAAAGAATCCAAAGAAACTAGCAATAAATATGCAGAATGATGTGGATGAAAAGGAGGATGACAATTACTATAAATGCGATCAGTGTGACAAATCCTACAAGTTTGTCATGCAACTGGTCAAACATAAGCAAAAGGTTCATGGAGTCAGCCAAATGCCCTCAAGCCGGGGATCTAGCGTGGCGGTTCCTCAACAGAGACCCAAATTGAACACAGACTCACTGGTGCATAGCCTTATCAAGGCAGTCGAAATCTCTGATGAGGATGGCAGTTCCAGTTCAGATAACTACTACAAATGCGATCAATGTGAGAAATCTTATAAATATGTGGTTAGTCTCATCAAGCACAAGCATAAGGACCATATGGAAAATTCTAAAGATTCAGCTGACGAGGAAGATCAAGCTCAGGCTTCCACATCCAACTCTGCCACCATTAGCGTTCCGTCAAAAACTTCTCGTATCAATCGTCGAGTTCAGGACTTTGACTTACTTCGCTGTCAACCGAATGGTTCCAAGGAGATTAAGTGCATGATATGTTTACGTCGTTTCGTCAAAGTGGGTGAACTGCGTCAACATCTGAAATACCATCCCGTTGACTTTAGTTTTGAGGCTCATGGCGAGCCAATTGAACGTATAGCCGAGGGCTTTTACAAGACAGCCGTCGAATCGACAGTGGAGGGCTTGAAGCGCCGTATTTTGAAGGATCTAAAAATGGGTTTCTATGGCCGGTACTACTCCATTACCAATGAGGCACGCTACGAGATGAGTTTGGATAGCTCCGATACGGATAGCGATGGCGGTGATGCAGATGCCCAGGTGATCTTACGGCGGAGCTATGCATGTGAATTGTGTGATTCCCCCAAAAAGCCAGCTATATGGCCTCGCAAATATCAACTGCATGAGCATCATAGGCAACACCACACCTGGCTGGAAGCTCCCTACGTTTGTCAGCGTTGTGATTCCCGCTTCTTGAGCGAACAACTTCTTGAACATCACACCAGTCAGCTTTGTAATAATACATTGAAACGTTTCCAATGCGACAAGTGTCCGCAGCGTTTCTTTTGGCGCAAGAATTTGCGTTCGCATTTGGTGGATCATAAAGATAAGCAAGAGAATTATCCGTGCGATCAATGCCAGCGTAGTTTTCAGGACAAAAGTTCTGTGACCAGGCACAAATTAATGATGCATGCAGATGGAAAGAGTCAGCTTATACCCTGCCGTTGGTGCACTCGGGTTTTCTATCGGACTGCCTTGTTGCATAAGCATCTCCAACGTCATGGTTTCAGTGGCCAAGACTTACCCTTGGCCGAAACATTGCTGGCCGATGCAGCAAAACCTTTGGGGCCAAAGAACATTCAATGCAAGCTCTGCGACCTTCGATTCGTTAGCATTGCAGACTTGCGTCGTCATATGGTTATGCTGGGACACGCTACTCAGATCTCCAGTTATATGATTAGCACTGAGGCTGGATTTGAACTGCAACTCGAAGATACGGATGATAGCGACGATGATGATGGCCACACAAAGAGATCCTACGCTTGTGATCTCTGCCAAATGAAATTCCCACGCAGGCGTGAGATGAGTGAGCATCAGTACTCGTTACATACGTTTGATAAACTGCCCCACACTTGCAATCAGTGTATATACAAAACTGTGGATAAGCTCATGTTAAAACATCATCAGCTGACTCAATGCCAAAACAAGGAGAAGAAATTCATTTGCTCGCATTGCGGCTACAGATTTATGTGGCAAGAGAATCTGGACAAGCATTTGTCCAGTCAGCATCCCAAACAAAAAACAAGCAATCAAGATCAACAGCCACAAATTTCTTCCATTCGTCGGAAAAGACGCTTCAGATACCAATGTCCACACTGTTGGCGCTCTTTTGTCGTTCAGCCCAGCTTGGACAAGCACATCAGAGACATGCATGTGGCCAAAAAGAATCCGGGAAAGAAATATTTATGTTCGCTATGCGGCCTGGAATCGCTTACTCCCAATAAATTAAGCATTCATATGCGTCGTCACATGGGAGAAAAACCCTTTAAATGCGATCTCTGCGACATGCGTTTCACTGTCCACTATGAACTGAAAGTGCACCGAAGAAAACACACGGGTGAACGTCCATATCAGTGTACGTTCTGTGACAAACATTTCGCTCGACCCGATAAACTGAGGCGTCACGTCTATATGCATAGCGATAAGCGTTAG
Protein Sequence
MTRICRVCAGPDGRFWIETPVENDKYAGKTFNQLLLDLTKIEVTLTQVEKLTPWICRNCAHKLQHSYDFVLKAKRTHEMWLEKMTDDLFCLSETPIHLMEIEGVTIKMEDTEQTAPTPAPCPVPDPLRNKCNQCSRTFRYVTNLYRHKQMEHTVEKEIKKNPKKLAINMQNDVDEKEDDNYYKCDQCDKSYKFVMQLVKHKQKVHGVSQMPSSRGSSVAVPQQRPKLNTDSLVHSLIKAVEISDEDGSSSSDNYYKCDQCEKSYKYVVSLIKHKHKDHMENSKDSADEEDQAQASTSNSATISVPSKTSRINRRVQDFDLLRCQPNGSKEIKCMICLRRFVKVGELRQHLKYHPVDFSFEAHGEPIERIAEGFYKTAVESTVEGLKRRILKDLKMGFYGRYYSITNEARYEMSLDSSDTDSDGGDADAQVILRRSYACELCDSPKKPAIWPRKYQLHEHHRQHHTWLEAPYVCQRCDSRFLSEQLLEHHTSQLCNNTLKRFQCDKCPQRFFWRKNLRSHLVDHKDKQENYPCDQCQRSFQDKSSVTRHKLMMHADGKSQLIPCRWCTRVFYRTALLHKHLQRHGFSGQDLPLAETLLADAAKPLGPKNIQCKLCDLRFVSIADLRRHMVMLGHATQISSYMISTEAGFELQLEDTDDSDDDDGHTKRSYACDLCQMKFPRRREMSEHQYSLHTFDKLPHTCNQCIYKTVDKLMLKHHQLTQCQNKEKKFICSHCGYRFMWQENLDKHLSSQHPKQKTSNQDQQPQISSIRRKRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHMGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSDKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00523880;
90% Identity
iTF_00555267;
80% Identity
-