Dfun008340.1
Basic Information
- Insect
- Drosophila funebris
- Gene Symbol
- zag-1
- Assembly
- GCA_018901825.1
- Location
- JAEIFK010000425.1:4182798-4185654[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.83 57 4.4 1.8 3 23 285 307 283 307 0.92 2 11 3.7 2.5e+02 2.4 2.1 3 21 458 476 456 480 0.91 3 11 0.18 13 6.4 1.2 2 23 502 524 501 524 0.94 4 11 0.011 0.76 10.3 0.7 1 23 541 564 541 564 0.95 5 11 0.0082 0.55 10.7 0.2 1 21 569 589 569 593 0.91 6 11 0.011 0.73 10.3 0.3 2 23 643 665 643 665 0.96 7 11 0.093 6.3 7.4 0.1 1 21 670 690 670 691 0.92 8 11 0.86 59 4.3 0.8 2 23 716 737 715 737 0.91 9 11 0.00015 0.01 16.1 2.8 2 23 750 770 749 770 0.97 10 11 2.5e-05 0.0017 18.6 4.6 1 23 776 799 776 799 0.97 11 11 0.79 53 4.5 0.5 1 11 825 835 825 837 0.84
Sequence Information
- Coding Sequence
- ATGAATGAATGCTTACAGATGGATGAACTGGAGGACACACATCTGTGCATCAAGTGCAATGCGACAATTGTGGGTCTGGAAAAGTACATAGAACATCGTAAACGGAGTTGCCTGAGCATTGCCAGAAATCAGCAGACGCAGCAGGTGAAGCAACAAGTGGTGGCTGCCACAACGTCAGCTGGAGCGACTCAACATAGCTATGATGGCTTTCATTTTGCAGAGCCGGAGGCACCGAGCAGCTATCTGCGCAAGACGACGGCCAGCCATGGGGGAAAGACGTCCAAGTCGTTGACGGAGGCCTATGATCCAACGTATGAACTGGGCGCCGATGTGTTCTTCTCATCGCTGCAGCTGCAGAGCGTCTCGACGGGCGGCAAGACGAGTGCACGTCCAGACCGTGCCAAGGAGGAGCAAAGTTGGCATGCGAGCAGCAATTGTACGGATCCGCTGTTGAAAGCGGTGCGGGAACAGGAGGAAAGCGTCTTTAAGCCATTGAAATTTGTGCATTCACCGGAGGCCAGTGACGAGGAGGAGGATGACGATGAGCCCGATGATTTCGATGATGATGAGCAGGAACATGATGCTGATGAGGACTACGATGCACGTCGTCATTCGCCACCAACTGTGCCAGCCACCCACACCGGCGGCAAATGGAAGCCCGAACATCGCCCGCAATTGCGTCACACGCATCTGGAACGCCTCTCGCCCAGCTGGGATGATCCACCCGACGAGGCACATGACCATCCGCCGGCGGAGCACACCCACGGCAAATGGGTGCCGGGCAGCAAGCAATTGGAATACCGTGAGAACATCGATCTAACCAAGCTGCAGCAACCGGGTGCCAGCTATTGGTGCAACATCTGCTGTCGTCGCCTCAAGTCGCGTCCCAACTACGAGCAGCATCTACGCAGTGGCTACCATCTTCGCCGGGCGGATGCCGAGCGTCAGTTGGAGCAGGCCAATCTGGAGGGTGCCAATCTTACGCTCAGCAAAGATTTCGAGCCAGTGCAGCTTGCAGAGCAGTTGGAACAGTTGCAGCCTTCAGCTCCACCTCCTACAAGTCGTCGTCGTCGTCGTCGTCGCACCAATCTACTGAGATGTGAGCTCTGTCGTCACAGCATGGCAAGGCATCTCATGGGCAAACATCTCATCTCCCATTTTCACTATCGTCGCCTGCAGCAGCAGCAGACGCAGCTGCGCCGTCAGAACTCTCTGCATGCCATCCTGGAGCACATGGGCAGCATTGTGAGGCAGGCGCCGTTCCAGTGTCTGCCCTGTCGATTCTATGCGAACACAGAGCAGGCATTTCAGGTCCATTGGCGCTCCTCCTCGCATGTGGAGCTCACCGAGCGTCTGGGCGGCGATTTCTGGTGCAGCTACTGTCAATTCGAGTGTGGCAGCAACGAGCAGATGTGGCAGCATCTGTTGCATGCCACACACAAGGAGGTGCTCTTGGCCCTCAATCGATCCGTGCCCGTTTGCATTGCCCAACGACGTCCGCTGCACTGTGACGTGTGCAGCGAGAGTTTCCTCTACAATCTGCAGTTGCGTCGTCACTTTGCCACCGAGCATGCTGGCCTGGTTGCCACAGGCAGCGCCTCGGATGCGTATCAGTGTCGCTATCGTTGCAACATTTGTGGCGCCGCACAGCGTTCGCGTGTGGCACTGCAGCGGCACGAGAAGCATCAGCATCAGTTGGCGCGTTATTATTGTACGCTTTGCGGCTTGGACTTTGAGACGCCACAAGAGGCGCGACGGCATCGCAGTCTCGTGGAACATGCGCGTCAACGGCAGCCGAGGCGACGACGACGCAAGCACAACGCTCAGCCGGAACGGGAGATTGAGCAGATGCTGCGCGAGGTGCTGGAGGAACAGGAGCCACAAGCGGAGCAGCCTGCGGCAGCCAAGAAACGTTGCCTGGCCAGACAATGCGCCAGTTGCAAGCTCAGCTTTGAAACGCCCCAGGCGCTGGTCGAGCATCGCCGCCAATCGCATCCCATGGACAATCATGCCTGCCTCAGCTGCGGCGCCAGCTTTCAGTCCGCCCAAGCGCTGGGACGTCACACACGCAGCTGTCAACCCATCGCCAGTTCCAGTTCCGCTGCCAACTCCAACTCGAGCTCCATTGCCAACTCCAAGTCCTGGAGCTGTGATCAGTGTGATTTCAGTTCTCAATACGAATCGGATTTGCTTTATCATCGCTTCTTTCATGTCCGTGACTCCTCCATTGGCAAGAACGAGCTCCTGCAATGTCCTCGCTGTCCCAAGCAGTTCCGCAAACATTCGCTGCGTGCTCATCTGCGTAATCACACGGACGAGCGCATCTTCGAGTGCAACGAGTGCCATTCCAAGTTTGCCAGGCGACATAATCTCAAGAATCATATGGCCACCATGCATCCAACTGCAACAACAGCAACAACAACGGAGAAGACGTCGTCCAAGCAACCAAATGGGGATAAGCCACGCAAGAAATTTCAATGCGACACCTGCGGCAAAATTCTGACCAAAAAGTGA
- Protein Sequence
- MNECLQMDELEDTHLCIKCNATIVGLEKYIEHRKRSCLSIARNQQTQQVKQQVVAATTSAGATQHSYDGFHFAEPEAPSSYLRKTTASHGGKTSKSLTEAYDPTYELGADVFFSSLQLQSVSTGGKTSARPDRAKEEQSWHASSNCTDPLLKAVREQEESVFKPLKFVHSPEASDEEEDDDEPDDFDDDEQEHDADEDYDARRHSPPTVPATHTGGKWKPEHRPQLRHTHLERLSPSWDDPPDEAHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKSRPNYEQHLRSGYHLRRADAERQLEQANLEGANLTLSKDFEPVQLAEQLEQLQPSAPPPTSRRRRRRRTNLLRCELCRHSMARHLMGKHLISHFHYRRLQQQQTQLRRQNSLHAILEHMGSIVRQAPFQCLPCRFYANTEQAFQVHWRSSSHVELTERLGGDFWCSYCQFECGSNEQMWQHLLHATHKEVLLALNRSVPVCIAQRRPLHCDVCSESFLYNLQLRRHFATEHAGLVATGSASDAYQCRYRCNICGAAQRSRVALQRHEKHQHQLARYYCTLCGLDFETPQEARRHRSLVEHARQRQPRRRRRKHNAQPEREIEQMLREVLEEQEPQAEQPAAAKKRCLARQCASCKLSFETPQALVEHRRQSHPMDNHACLSCGASFQSAQALGRHTRSCQPIASSSSAANSNSSSIANSKSWSCDQCDFSSQYESDLLYHRFFHVRDSSIGKNELLQCPRCPKQFRKHSLRAHLRNHTDERIFECNECHSKFARRHNLKNHMATMHPTATTATTTEKTSSKQPNGDKPRKKFQCDTCGKILTKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00608801; iTF_00558280; iTF_00537864; iTF_00507217; iTF_00584049; iTF_00610999; iTF_00569324; iTF_00602202; iTF_00585568;
- 90% Identity
- -
- 80% Identity
- -