Dqui007676.1
Basic Information
- Insect
- Drosophila quinaria
- Gene Symbol
- zag-1
- Assembly
- GCA_035047525.1
- Location
- JAWNPO010000396.1:310089-328554[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.26 21 6.2 2.1 3 23 300 322 298 322 0.92 2 13 1.9 1.6e+02 3.4 2.3 3 21 463 481 461 485 0.91 3 13 0.083 6.6 7.8 0.4 2 23 507 529 506 529 0.94 4 13 0.046 3.7 8.6 1.0 1 23 546 569 546 569 0.95 5 13 0.049 3.9 8.5 0.1 1 21 574 594 574 598 0.91 6 13 0.021 1.7 9.6 0.2 2 23 652 674 652 674 0.95 7 13 0.49 39 5.3 0.1 1 21 679 699 679 700 0.92 8 13 0.96 77 4.4 0.4 2 20 722 740 721 743 0.89 9 13 0.0002 0.016 16.0 2.8 2 23 756 776 755 776 0.97 10 13 3.3e-05 0.0026 18.5 4.6 1 23 782 805 782 805 0.97 11 13 0.00016 0.013 16.3 0.6 1 23 851 873 851 873 0.97 12 13 0.65 52 5.0 0.5 1 23 880 904 880 904 0.96 13 13 9.8 7.8e+02 1.2 0.7 1 18 909 928 909 928 0.92
Sequence Information
- Coding Sequence
- ATGCAGGACGAGTCGGATGAGCTGGAGGACACGCATTTGTGCATCAAGTGCAATGCGACGATTGTGGGACTGGAGAAGTACATTGAGCATCGAAAGAGGAGTTGCCTGAGCATCGCGAGAAATCAGAGGCAGCAGGAAAAACAGGTGgtggccacaacaacaacagcagcaacaacaacagcagcgtcGGCAGCGACGGATAACAGCTATGATGGCTTCCACTTTGCGGAGCCGGAGGCACCGAGCAGCTATCTGCGCAAGACGACGGCCAGTCACGGGGGCAAGACATCCAAGTCCCTGACGGAGGCCTATGATCCCACCTATGACCTTGGCGCGGATCTCTTCTTCTCCTCCCTCCAGCTGCAAAGCGTCTCGACGGGCGGCAAGTCGAGTGCTCGCCCTGAGCGGGCCAAGGAGGAGACGAGCTGGcatggcagcaacagctgcacgGATCCTCTGCTGAAAGCGGTGCGGGAACAGGAGGAATCCGACTTTAAGCCACTGAAATTCGTGCACTCACCCGAGGCTagtgaggaggaggaggaggacgatGAACCGGATGACTTTGAGGATGATGAACAGGAGCACGACCACGAGCACGAGCACGAACACGAGCACGAGCACGATGCTGAGGAGGATTTCGATGCGCGTCATCACTCGCCACCAGCTGTGCCGGCGACGCACACGGGCGGCAAGTGGAAGCCGGAGCATCGTCCCCAGCTGCGGCACACGCACCTCGAACGCATCTCGCCCAGCTGGGACGATCCGCCCGAGGAGTCACACGACCATCCGCCGGCGGAGCACACACATGGCAAATGGGTGCCGGGCAGCAAGCAGCTGGAGTACCGCGACAACATCGACTTGACCAAGTTGCAACAGCCGGGTGCAAGTTACTGGTGCAACATCTGCTGTCGCCGCCTCAAGACCTTGTCCAACTACGAGCAGCATCTGCGCAGTGGCTACCACCACCGTCGGGCGGATCCGGAGCGGCAGCTGGAGCAGGCCCATCTCGAGGCGGCCAATCTCACACTCGCCAAGGACTTTGAGCCAGTGCAGCATGTGGAGCAGCTGCCacctcgtcgtcgtcgccgtcgcgCCAATTTGTTGAGATGCGAGCTCTGCCGGCACAGCATGGCCAGGCATCTGATGGGCAAGCACCTCATCTCCCACTTCCACTACCGACgcctgcagcagcagcagcagacgcAGCTGCGCCGCCAGAACTCCCTTCACGCCATCCTGGAGCACATGGGCAGCATCGTGCGGCAGGCGCCTTTCCAGTGTCTGCCCTGCCAATTCTACGCCAACACGGAGCACGCTTTTCAGGTCCATTGGCGCTCTTCCTCGCATGTGAAACTCACCGAGCGACTGGGCGGCAATTTCTGGTGCAGCTACTGTCAGTTCGAGTGTGGCAGCAACGAGCAGATGTGGCGGCATCTGCTGCACGCCACGCACAAGGAAGTGCTCCTGGCGCTCAATCGCTCCGTGCCCGTTTGCATTGCCCAACGGCGTCCGCTGCGCTGCAATGTGTGCAACGAGGGCTTCCTCTACAATCTGCAGCTGCGCCGTCACTTTGCCACAGAGCATGCGGGGTTGGTGGCCACGGGCAGCGCCTCGGACGAGTATCAGTGTCGCTTCCGCTGCAGCATCTGTGGCGCCCCACAGCGGTCACGGGTGGCATTACAGCGGCACGAGAAGCACAAGCATCAACTGGCCAGATACTACTGTGCCCTCTGTGATCTGGAGTTCGAGACGCCGCAGGAGGCGCGTCGTCATCGCAGCCTCGTGCAACATGCGCGACGACAGCCGAGACGCAAGTTCCGAGCACAGCCCGAGCGGGACATTGAGCACATGCTGCGAGAGGTCCTGGAGGATCAGGAGGAGCTGCCAAATAAATCGGATGAGCAGTCGGAGGATCAGCCTTTAGCTGCCAAGAAGCGTTGCCTGGTCCGACAATGCGCCAGTTGCGAGCTCAGCTTCGAGACGCCTCAGGCGCTGGTCGAGCATCGCCGTCAGACGCATCCGATGGACAATCACGCCTGCCTCAGCTGCGGAGGCAGCTTTCAGTCCGCCCAGGCGCTGGGACGGCACACGCGGAGTTGTCAACCCACCGCATCCAGCTCCACATCCGCATCCAACGACAACTCAGAGTCCAAGTGCTGGCAGTGTGATCAGTGCGATTTCAGCTCCCAATACGAGTCGGATTTGATCTATCATGGCTTTTTTCATTCCCGGGATTTGTCTATTGGTAAAAACGAGCTGCTTCAATGTCCTCGCTGTCCTAAACAATTCCGTAAGCATTCGCTTCGTGCTCATCTTCGCAATCACACGGATGAACGCATCTTCGAGTGCAACGAGTGCCATTCCAAGTTTGCCAGGCGACACAATCTCAAGAATCACATGGCCACCATGCATccaacaaccgcaacaacaacaacaacggcaacagcaacaaccacagcaacaacaataacaagcacTGCAAACaccgcaacaacaattgacaaaTCGAAGCCTATCAAACCAGATCAGGATAATCCCCGCAAGAAATTTCAATGCGGCATTTGTGGCAAAATTCTGACCAAAAAATTCTCCTTGAAACAACATGAAATGCTTCACACTGAGGTGGAACGTCGATTTCGTTGTCAGTTTGAGGACTGTCACTATGCGGGCCTCACTCCGGAAGCTCTCAAGACTCACCTGCTGTCCCACGCCGAGGGCAGTCACAAGTGTTCCCACGAAAACTGCAACTACGTGGGCAAGAGTGAGCAACACTTGAAGAGGTAA
- Protein Sequence
- MQDESDELEDTHLCIKCNATIVGLEKYIEHRKRSCLSIARNQRQQEKQVVATTTTAATTTAASAATDNSYDGFHFAEPEAPSSYLRKTTASHGGKTSKSLTEAYDPTYDLGADLFFSSLQLQSVSTGGKSSARPERAKEETSWHGSNSCTDPLLKAVREQEESDFKPLKFVHSPEASEEEEEDDEPDDFEDDEQEHDHEHEHEHEHEHDAEEDFDARHHSPPAVPATHTGGKWKPEHRPQLRHTHLERISPSWDDPPEESHDHPPAEHTHGKWVPGSKQLEYRDNIDLTKLQQPGASYWCNICCRRLKTLSNYEQHLRSGYHHRRADPERQLEQAHLEAANLTLAKDFEPVQHVEQLPPRRRRRRANLLRCELCRHSMARHLMGKHLISHFHYRRLQQQQQTQLRRQNSLHAILEHMGSIVRQAPFQCLPCQFYANTEHAFQVHWRSSSHVKLTERLGGNFWCSYCQFECGSNEQMWRHLLHATHKEVLLALNRSVPVCIAQRRPLRCNVCNEGFLYNLQLRRHFATEHAGLVATGSASDEYQCRFRCSICGAPQRSRVALQRHEKHKHQLARYYCALCDLEFETPQEARRHRSLVQHARRQPRRKFRAQPERDIEHMLREVLEDQEELPNKSDEQSEDQPLAAKKRCLVRQCASCELSFETPQALVEHRRQTHPMDNHACLSCGGSFQSAQALGRHTRSCQPTASSSTSASNDNSESKCWQCDQCDFSSQYESDLIYHGFFHSRDLSIGKNELLQCPRCPKQFRKHSLRAHLRNHTDERIFECNECHSKFARRHNLKNHMATMHPTTATTTTTATATTTATTITSTANTATTIDKSKPIKPDQDNPRKKFQCGICGKILTKKFSLKQHEMLHTEVERRFRCQFEDCHYAGLTPEALKTHLLSHAEGSHKCSHENCNYVGKSEQHLKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00510899;
- 90% Identity
- iTF_00534215;
- 80% Identity
- -