Dsub009243.1
Basic Information
- Insect
- Drosophila suboccidentalis
- Gene Symbol
- zag-1
- Assembly
- GCA_037043435.1
- Location
- JBAMBK010001398.1:27389-31289[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 1.4 1e+02 3.9 1.5 3 23 296 318 294 318 0.91 2 11 1.2 88 4.1 2.3 3 21 458 476 456 480 0.91 3 11 0.11 7.8 7.4 0.3 2 23 502 524 501 524 0.94 4 11 0.043 3.1 8.7 1.0 1 23 541 564 541 564 0.95 5 11 0.053 3.9 8.4 0.2 1 21 569 589 569 593 0.91 6 11 0.019 1.4 9.8 0.1 2 23 647 669 647 669 0.95 7 11 0.11 8.4 7.3 0.1 1 21 674 694 674 695 0.92 8 11 2 1.4e+02 3.4 0.6 2 20 717 735 716 738 0.88 9 11 0.00019 0.014 16.1 2.8 2 23 751 771 750 771 0.97 10 11 3e-05 0.0022 18.6 4.6 1 23 777 800 777 800 0.97 11 11 0.28 20 6.1 0.3 1 12 849 860 849 861 0.87
Sequence Information
- Coding Sequence
- ATGCAGGACGAGTCGGATGAGCTGGAGGACACGCATTTGTGCATCAAGTGCAACGCGACGATTGTGGGATTGGAAAAGTACGTTGAGCATCGTAAGAGGAGTTGCCTGAGCATCGCCAGAAATCAGAGGCAGCAGGAAAAGCAGGCGGTGGCCACAAtcacagcaacaccaacaacaacaacagcgtcgGGAGCGACGGATCACAGCTATGATGGCTTCCACTTTGCGGAACCGGAGGCACCGAGCAGTTATCTGCGCAAGACGACGGCGAGCCATGGGGGAAAGACATCCAAGTCCCTGACGGAGGCCTATGATCCCACCTACGAACTTGGTGCGGATCTCTTCTTCTCCTCCCTCCAGCTGCAGAGCGTGTCGACGGGCGGGAAGTCGAGTGCTCGGCCCGAGAGGGCCAAGGAGGAGACGAGCTGGCatgccagcaacaactgcaCGGATCCCCTGCTGAAAGCGGTGCGGGAACAGGAGGAATCCGACTTTAAGCCGCTGAAATTCGTGCACTCACCCGAGGCCagtgaggaggaggaggacgacgATGAACCAGATGACTTTGAGGATGATGATCAGGAGCAGGATCACGAGCACGATCACGACCATGAGGCTGACGAGGATTTCGATGCACGTCGTCACTCGCCACCAGCTGTGCCGGCGACACACACGGGCGGCAAGTGGAAGCCGGAGCATCGTCCCCAGCTGCGACACACGCACCTCGAACGCATCTCGCCCAGCTGGGATGATCCGCCCGAGGAGTCGCACGACCATCCGCCGGCGGAGCACACGCATGGCAAATGGGTGCCGGGCAGCAAACAGTTGGAGTACCGCGAAAACATCGACCTGACCAAGCTGCAGCAACCGGGTGCAAGTTATTGGTGCAACATCTGCTGTCGCCGCCTCAAGACGCTGCCCAACTACGAGCAGCATCTGCGCAGTGGCTACCACCACCGTCGCGCGGATCCAGAGCGTCAGCTGGAGCAGGCCAACCTCGAGGGCGCCAATCTCACACTGGCCAAGGACTTTGAGCCCGTGCAGCAggtggagcagctgcagcctcgtcgtcgtcgccgtcgcgcCAACTTGTTGAGATGCGAGCTCTGCCGGCACAGCATGGCCAGGCATCTGATGGGCAAGCACCTCATCTCCCACTTCCACTACCGACgcctgcagcagcagcagacgcaGCTGCGCCGCCAGAGCTCCCTGCACGCCATCCTCGAGCACATGGGCAGCATCGTGCGGCAGGCGCCGTTCCAGTGCCTGCCCTGCCAGTTCTACGCCAACACGGAGCAGGCTTTTCAGGTCCATTGGCGCTCCTCCTCGCATGTGAAGCTCACCGAGCGACTGGGCGGCGATTTCTGGTGCAGCTACTGTCAGTTCGAGTGCGGCAGCAACGATCAGATGTGGCGGCATTTGTTGCACGCCACGCACAAGGAAGTGCTCCTGGCCCTCAATCGCTCCGTGCCCGTTTGCATTGCCCAGCGGCGTCCGCTGCGCTGCGATGTGTGCAACGAGGGCTTCCTCTACAATCTGCAGCTGCGTCGTCACTTTGCCACCGAGCATGCGGGATTGGTGGCCACGGGCAGCGCCTCGGACGAGTATCAGTGTCGCTTCCGCTGCAGCATCTGTGGCGCCCCACAGCGGTCGCGGGTGGCATTACAGCGACACGAGAAGCACAAACATCAACTGGCCAGATACTACTGTGCCCTCTGCGATCTGCAGTTCGAGACGCCGCAGGAGGCGCGTCGTCATCGCAGCCTCGTGCAACATGCGCGACGGCAGCCGCGACGCAAGTTCCGAGCACAGCCCGAGCGGGACATTGAGCACATGCTGCGCGAGGTCCTGGAGGATCAGGAGGAGTTGCCAGAAAAATCGGATCCACAGTCGGAGGATCATCGTTTAGCTGCCAAGAAGCGTTGCCTGGTCCGACAATGCGCCAGTTGCGAGCTCAGCTTTGAGACGCCTCAGGCGCTGGTCGAGCATCGTCGTCAATCGCATCCGATGGACAATCACGCCTGTCTCAGCTGCGGCGCCAGCTTTCAGTCCGCCCAGGCGCTGGGACGCCACACGCGCAGTTGTCAACCCACCGCATCCTGTTCCACATCCGCATCCAACGCCAACTCAGAGTCCAAATCCTGGCGCTGTGATCAGTGCGATTTCAGCTCTCAATACGAGTCGGATTTGCTCTATCATGGCTTCTTTCATTCCCGTGATTCGTCTATTGGTAAGAACGAGCTTCTCCAGTGTCCTCGCTGTCCTAAACAATTCCGTAAGCATTCCCTTCGTGCTCATCTGCGCAATCACACGGATGAACGCATCTTCGAGTGCAACGAGTGCCATTCCAAGTTTGCCAGGCGACACAATCTCAAGAATCACATGGCCACCAtgcatgcaacagcaacaacaacaaccacagcaacaacaacagaaacaacaacaaccactgcaacaacaacaacaaccactgcAAACACCGCAACAACAGCTGAAAAATCTAAGCCTATGAAACCAGATCACGATAATCCCCGCAAGAAATTTCAATGCGGCATTTGTGGCAAAGTTCTGACCAAAAAGTAA
- Protein Sequence
- MQDESDELEDTHLCIKCNATIVGLEKYVEHRKRSCLSIARNQRQQEKQAVATITATPTTTTASGATDHSYDGFHFAEPEAPSSYLRKTTASHGGKTSKSLTEAYDPTYELGADLFFSSLQLQSVSTGGKSSARPERAKEETSWHASNNCTDPLLKAVREQEESDFKPLKFVHSPEASEEEEDDDEPDDFEDDDQEQDHEHDHDHEADEDFDARRHSPPAVPATHTGGKWKPEHRPQLRHTHLERISPSWDDPPEESHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTLPNYEQHLRSGYHHRRADPERQLEQANLEGANLTLAKDFEPVQQVEQLQPRRRRRRANLLRCELCRHSMARHLMGKHLISHFHYRRLQQQQTQLRRQSSLHAILEHMGSIVRQAPFQCLPCQFYANTEQAFQVHWRSSSHVKLTERLGGDFWCSYCQFECGSNDQMWRHLLHATHKEVLLALNRSVPVCIAQRRPLRCDVCNEGFLYNLQLRRHFATEHAGLVATGSASDEYQCRFRCSICGAPQRSRVALQRHEKHKHQLARYYCALCDLQFETPQEARRHRSLVQHARRQPRRKFRAQPERDIEHMLREVLEDQEELPEKSDPQSEDHRLAAKKRCLVRQCASCELSFETPQALVEHRRQSHPMDNHACLSCGASFQSAQALGRHTRSCQPTASCSTSASNANSESKSWRCDQCDFSSQYESDLLYHGFFHSRDSSIGKNELLQCPRCPKQFRKHSLRAHLRNHTDERIFECNECHSKFARRHNLKNHMATMHATATTTTTATTTETTTTTATTTTTTANTATTAEKSKPMKPDHDNPRKKFQCGICGKVLTKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00510899;
- 90% Identity
- iTF_00534215;
- 80% Identity
- -