Basic Information

Insect: Drosophila falleni
Gene Symbol: -
Assembly: GCA_035045575.1
Location: JAWNOV010000075.1:52348-77451[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.82 61 4.5 1.9 3 23 256 278 254 278 0.92

2 15 4.8 3.6e+02 2.1 2.1 3 21 424 442 422 446 0.91

3 15 0.0044 0.33 11.6 0.2 2 21 468 487 467 490 0.88

4 15 0.24 18 6.2 3.0 1 23 507 530 507 531 0.95

5 15 0.76 57 4.6 0.1 1 21 535 555 535 559 0.88

6 15 0.058 4.3 8.1 0.4 2 23 613 635 613 635 0.95

7 15 0.33 25 5.7 0.2 1 21 640 660 640 661 0.92

8 15 7.5 5.6e+02 1.5 0.6 2 20 685 703 684 706 0.86

9 15 0.0002 0.015 15.9 2.8 2 23 719 739 718 739 0.97

10 15 6.7e-06 0.0005 20.5 3.7 1 23 745 768 745 768 0.97

11 15 8.9e-05 0.0067 17.0 0.8 1 23 816 838 816 838 0.97

12 15 0.77 58 4.6 2.3 1 23 845 869 845 869 0.97

13 15 0.12 8.7 7.2 8.3 1 23 874 898 874 898 0.97

14 15 0.0013 0.099 13.3 0.6 1 23 903 925 903 925 0.98

15 15 0.00079 0.059 14.0 5.8 1 21 931 951 931 956 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.82	61	4.5	1.9	3	23	256	278	254	278	0.92
2	15	4.8	3.6e+02	2.1	2.1	3	21	424	442	422	446	0.91
3	15	0.0044	0.33	11.6	0.2	2	21	468	487	467	490	0.88
4	15	0.24	18	6.2	3.0	1	23	507	530	507	531	0.95
5	15	0.76	57	4.6	0.1	1	21	535	555	535	559	0.88
6	15	0.058	4.3	8.1	0.4	2	23	613	635	613	635	0.95
7	15	0.33	25	5.7	0.2	1	21	640	660	640	661	0.92
8	15	7.5	5.6e+02	1.5	0.6	2	20	685	703	684	706	0.86
9	15	0.0002	0.015	15.9	2.8	2	23	719	739	718	739	0.97
10	15	6.7e-06	0.0005	20.5	3.7	1	23	745	768	745	768	0.97
11	15	8.9e-05	0.0067	17.0	0.8	1	23	816	838	816	838	0.97
12	15	0.77	58	4.6	2.3	1	23	845	869	845	869	0.97
13	15	0.12	8.7	7.2	8.3	1	23	874	898	874	898	0.97
14	15	0.0013	0.099	13.3	0.6	1	23	903	925	903	925	0.98
15	15	0.00079	0.059	14.0	5.8	1	21	931	951	931	956	0.93

Sequence Information

Coding Sequence: ATGCATAACGAGTCGGATGAACTGGAGGACACACATCTGTGCATCAAGTGCAATGCGACGATTGTTGGACtggaaaaatatatagaacacCGCAAAAGGAGTTGCCTAAGCATTGACAGAAGTCAGACGCAGCAGGAAAAACAGGAGGTGGCGAGAACAACATCGGGAGCCACGGATCATAGCTATGATGGCTTCCACTTTGCGGAACCGGAGGCACCGAGCAGTTATCTGCGCAAGACGACGGCCAGTCATGGAGGAAAGACATCCAAGTCCTTGACGGAGGCCTATGATCCGACCTATGAACTGGGTGCCGATGTGTTCTTCTCCTCGCTCCAACTGCAGAGTGTCTCGACGGGCGGCAAGACGAGTGCACGTCCCGAAAGGGCCAAGGAGGAGACGAGTTGGCATGCCGGCAGCAGGTGTACAGATCCTCTGCTGAAAGCGGTGCGGGAACAGGAGGAATCTGACTTTAAGCCACTGAAATTCgATCACGATGCGGACGAGGATTACGATGCACGTCGTCACTCGCCACCAGCTGTGCCGGCAACCCACACGGGCGGCAAGTGGAAGCCCGAGCATCGTCCACAGTTGCGTCACACGCATCTTGAACGCATCTCGCCCAGCTGGGATGAGCCACCAGAGGAGTCACATGACCATCCGCCAGCGGAGCACACACATGGCAAATGGGTGCCGGGCAGTAAACAGTTGGAGTACCGCGAAAACATCGACTTGACCAAGTTGCAACAACCGGGCGCAAGTTATTGGTGCAACATCTGCTGTCGTCGCCTCAAGACGCGTCCCAACTACGAGCAACATCTGCGCAGTGGCTACCATCAACGCCGGGCGGATGCAGAGCGTCAGTTGGAGCAGGCCAATCTCGAAGGCGTCAATCTTACACTTGCCAAAAACTTCGAGCCAGTGCAGCATGTGGAGCCCGTGGAGCCCGTGGAGCAGCTGCCAACTCATCGGCGTCGCCGTCGCGCCAATCTGCTGAGATGTGAGCTCTGCCGGCACAGCATGGCCAGACATCTCATGGGCAAGCATCTCATTTCCCACTTTCACTATCGACgcctgcagcaacagcagacaCAAGTGCGTCGCCAGAACTCCCTGCATGCCATCCTCGAGCACATGGGCAGCATTGTGAGGCAGGCGCCTTTCCAGTGTCTTCCCTGTCAGTTCTATGCCAACACTGAGCAGGCTTTTCAGgtCCATTGGCGCTCCGCCTCGCATCTGGAACTTACCGAGCGCCTGGGCGGCGATTTCTGGTGCAGCTACTGTCAGTTTGAGTGTGGCAGCAACGAGCAGATGTGGCAGCATCTGTTGCATGCCACGCACAAGGAAGTGCTTCTCGCACTCAATCGCTCCGTGCCCGTTTGCATTGCCCAACGTCGTCGGCTGCGCTGCGAGGTGTGCAGCGAAAGTTTCATCTACAACTTGCAGTTGCGTCGTCACTTTGCCGCAGAGCATGTCGCATTGGTTGCCACAGGCAGCGCCTCGGATGAATATCAGTGTCGCTACCGTTGCAGCACTTGTGGCGCCGCCCAGCGGTCACGTGTGGCACTGCAGCGACACGAGAAGCACAAACATCACCTGGCCAGATACTATTGTGCCCCTTGTGGCCTGGAGTTCGAGACGCCGCAAGAAGCGCGACGGCATCGCAGCCTCGTGCAACATGTGCGACGCCAGCCGAGACGCAAGTTCGTTGCACAGCCGGAGCGTGAAATTGAGCATATGCTACGTGAGGTACTGGAGGATCAGGAGGAGGTGTCAAAACCATCGGATCAACAGTCGGAGGATCAACCTTCAGCTGCCAAGAAACGTTGCCTGGTCAGACAATGCGCCAGTTGCAAGCAGAGCTTTGAGACGCCTCAGGTATTAGTCGAGCATCGCCGTCAGTCGCATCCCATGGACAATCATGCCTGTCTCAGCTGCGGCAGCAGCTTTCAGTCCGCCCAGGCACTTGGTCGCCACACACGCAGCTGTCAACCCATCGCCTCcacatcgaaatcgaattccAAAACCGAATCCAGCTTAGAATCCAAATCCTGGCGCTGTGATCAGTGTGATTTTAACTCTCAATACGAGTCGGATTTGCTATATCATGGCTTCTTCCATTCCCGTGACTCGGCCATCGGTAAGAACGAGCTACTCCAATGTCCGCGCTGTCCTAAACAATTCCGCAAGCATTCTCTTCGTGCTCATCTTCGCAATCACACGAATGAGCGCATCTTCGAGTGCAACGAGTGTCATGCCAAGTTTGCCCGACGACACAATCTCAAGAATCACATGGCCACcatgcatgcaacaacaaccgcagcagcagcaacaacaacagccgaaacaacaacaacaacagctacagcaacaacaaacgctGCAACGGAAACAACAACTGCGAAGGTGACGCCCAAGAAATCAAATGGAGATAATCCCCGTAAGAAATTTCAATGCGACATTTGCGGCAAAATTCTGACCAAAAAATTCTCCTTGAAGCAACATGAAATGCTTCACTCTGAGGTAACACGTAGTTTTCGCTGTCATTTTAAGGACTGTCACTATGCAGGCCTTACTCCGGAAGCTCTCAAGACCCACCTGCTCTCCCATGCCGAGGGCAGTCACAAGTGTTCCCACGAAAACTGCAAGTATGTGGGCAAAAGTAAGCAGCACTTAAAGAGACACCTCAAATCACATGTGAGCGAAAAATATGCCTGCGATCAGTGCGATTTCAGGGCCCGCATCAAGGGTCAGCTAAAGCGTCACATGCTTCGTCACACGGGGGAAAAGTCTCACAAGTGCCCCCACTGCGACTTTCGGTGCAGCACCTTTGACAACCTGCGAAAACACATTATCAAAACGGGCAAGCATCCCGGCAAGTTTATCTACGAGTGTACCTACTGTACAGACACCGATCGCCAGACGGCCAGCATGTTCAAAACCAATAGCTTCAAAGAGTATCAGCTGCATTTAAACACACATAAAACACACTTATCTTAA
Protein Sequence: MHNESDELEDTHLCIKCNATIVGLEKYIEHRKRSCLSIDRSQTQQEKQEVARTTSGATDHSYDGFHFAEPEAPSSYLRKTTASHGGKTSKSLTEAYDPTYELGADVFFSSLQLQSVSTGGKTSARPERAKEETSWHAGSRCTDPLLKAVREQEESDFKPLKFDHDADEDYDARRHSPPAVPATHTGGKWKPEHRPQLRHTHLERISPSWDEPPEESHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTRPNYEQHLRSGYHQRRADAERQLEQANLEGVNLTLAKNFEPVQHVEPVEPVEQLPTHRRRRRANLLRCELCRHSMARHLMGKHLISHFHYRRLQQQQTQVRRQNSLHAILEHMGSIVRQAPFQCLPCQFYANTEQAFQVHWRSASHLELTERLGGDFWCSYCQFECGSNEQMWQHLLHATHKEVLLALNRSVPVCIAQRRRLRCEVCSESFIYNLQLRRHFAAEHVALVATGSASDEYQCRYRCSTCGAAQRSRVALQRHEKHKHHLARYYCAPCGLEFETPQEARRHRSLVQHVRRQPRRKFVAQPEREIEHMLREVLEDQEEVSKPSDQQSEDQPSAAKKRCLVRQCASCKQSFETPQVLVEHRRQSHPMDNHACLSCGSSFQSAQALGRHTRSCQPIASTSKSNSKTESSLESKSWRCDQCDFNSQYESDLLYHGFFHSRDSAIGKNELLQCPRCPKQFRKHSLRAHLRNHTNERIFECNECHAKFARRHNLKNHMATMHATTTAAAATTTAETTTTTATATTNAATETTTAKVTPKKSNGDNPRKKFQCDICGKILTKKFSLKQHEMLHSEVTRSFRCHFKDCHYAGLTPEALKTHLLSHAEGSHKCSHENCKYVGKSKQHLKRHLKSHVSEKYACDQCDFRARIKGQLKRHMLRHTGEKSHKCPHCDFRCSTFDNLRKHIIKTGKHPGKFIYECTYCTDTDRQTASMFKTNSFKEYQLHLNTHKTHLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00510899;
90% Identity: -
80% Identity: -