Basic Information

Insect: Drosophila biarmipes
Gene Symbol: hang
Assembly: GCA_018148935.1
Location: JAECYG010000274.1:20561100-20570272[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.27 16 5.9 1.0 3 23 303 324 302 324 0.93

2 18 0.89 53 4.3 3.1 3 22 432 451 430 451 0.89

3 18 0.00059 0.035 14.3 3.3 1 22 567 588 567 590 0.90

4 18 0.068 4.1 7.8 0.1 2 21 602 621 601 622 0.93

5 18 0.00069 0.041 14.1 0.2 2 23 765 787 764 787 0.95

6 18 0.002 0.12 12.7 0.1 1 23 795 818 795 818 0.96

7 18 1.6e-05 0.00095 19.3 0.1 2 23 903 924 902 924 0.97

8 18 0.00028 0.017 15.3 2.9 2 23 1006 1028 1005 1028 0.97

9 18 0.022 1.3 9.4 0.2 2 23 1037 1059 1036 1059 0.95

10 18 0.006 0.36 11.1 0.1 1 23 1072 1095 1072 1095 0.97

11 18 0.00012 0.0074 16.5 1.1 1 23 1157 1179 1157 1179 0.99

12 18 0.0019 0.11 12.7 0.9 1 23 1187 1210 1187 1210 0.96

13 18 8.3 4.9e+02 1.3 0.2 2 13 1218 1229 1218 1231 0.85

14 18 3.2e-05 0.0019 18.3 1.4 3 23 1328 1348 1327 1348 0.98

15 18 0.005 0.3 11.4 0.1 1 23 1383 1405 1383 1405 0.97

16 18 0.82 49 4.4 0.1 2 20 1453 1471 1452 1473 0.91

17 18 0.0065 0.39 11.0 0.4 3 23 1488 1508 1488 1508 0.98

18 18 0.0001 0.006 16.7 2.1 1 23 1785 1807 1785 1807 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.27	16	5.9	1.0	3	23	303	324	302	324	0.93
2	18	0.89	53	4.3	3.1	3	22	432	451	430	451	0.89
3	18	0.00059	0.035	14.3	3.3	1	22	567	588	567	590	0.90
4	18	0.068	4.1	7.8	0.1	2	21	602	621	601	622	0.93
5	18	0.00069	0.041	14.1	0.2	2	23	765	787	764	787	0.95
6	18	0.002	0.12	12.7	0.1	1	23	795	818	795	818	0.96
7	18	1.6e-05	0.00095	19.3	0.1	2	23	903	924	902	924	0.97
8	18	0.00028	0.017	15.3	2.9	2	23	1006	1028	1005	1028	0.97
9	18	0.022	1.3	9.4	0.2	2	23	1037	1059	1036	1059	0.95
10	18	0.006	0.36	11.1	0.1	1	23	1072	1095	1072	1095	0.97
11	18	0.00012	0.0074	16.5	1.1	1	23	1157	1179	1157	1179	0.99
12	18	0.0019	0.11	12.7	0.9	1	23	1187	1210	1187	1210	0.96
13	18	8.3	4.9e+02	1.3	0.2	2	13	1218	1229	1218	1231	0.85
14	18	3.2e-05	0.0019	18.3	1.4	3	23	1328	1348	1327	1348	0.98
15	18	0.005	0.3	11.4	0.1	1	23	1383	1405	1383	1405	0.97
16	18	0.82	49	4.4	0.1	2	20	1453	1471	1452	1473	0.91
17	18	0.0065	0.39	11.0	0.4	3	23	1488	1508	1488	1508	0.98
18	18	0.0001	0.006	16.7	2.1	1	23	1785	1807	1785	1807	0.98

Sequence Information

Coding Sequence: ATGCGCACACACTGTTATCAGAGCCAGCAGGACATTTCATATGATTTGCGCAGTGTTCTGCGTCCGTGGTGGGGGGCGGCAGAGGGTGGCAGTGGGCGGTGGGCGGATGGCAAGATCACACCGCAGGATCGGCTGTCGCTGCAGATCTGCCACGCCTGCATCAGCTACCTGAACTCGTGGCAGAGCTTCAAGAACCGCTGCTTCAGCTCGCAGACCAAGCAGCGCCAGTGGCTGGACCCGAAGCTGTTCATGCCCTTGGACATAGCAGTGCCGCCATTGCCACCACTGCCGCCAGTGGCTCCGGTATCGATTGCTCCGCCCGCTGGTGCTGCTGAACTGCTGCCCGGGATGTCTGGTGTGGGTGGAATGGAGAGCTTGTCGCTGTCGCTGCCGCTTGATTTCAGCCAGGGCTGCAGCAGCAGCAGCGGTCACGTCCAACAACAGCAGCAGCAGGCGGCTGGTGGCCTGGTCACAGCGACGTCCACGTCCAATGCGCCGGGCAGCGTCGTTTCCGCCACAGCCACGGCCTCTGTCTCGGGCTCAGCCTCGGCCTCAGCCGCTGCCTGTGCAACTGCATCTGCAGCATCTGCAAGTGCAACTGCAACTGCATCCGCATCCGTGTCCACGGCTCCGCTGCTTATGCCGCCACTGCCTGCGATCCCCATCAAAGATGAGCCCATTGACACGGATGACGACTACCAGATGAAGTCAATAGACGAGTCCGACGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGACGTGCCGCTGACGGCCTCGGACTACGACTACACTGCGCAGCATGGCGTGAATGCCTCTTCCGTTGCCGCCTCGCTGCCGGCGAATGCGGTGGCCAATGTGGCAGCGGCCGGCGACTCCAAGGTGGCCAGCTGCCGCGCCTGCAGCCTGCAGTTCTCCACCCGGGCCAACGCCCGTCGCCACGAACGCAATCTGCACCCGAATCTGTTCCAGCTGTCCACCGACTCGCCCCACAACACGCCCATCACGAAGCCAACGCCCGCGCTGGCTGCCGCCCTGGAGATCCAACGGGCAGCGGCTGCGGCGGCCACGGCGGAGGCCAACCGGGCGGCGGGCGCTGCGGGCGGCAACATCTCCACGCAGAAGTACCGCCAGGTGGTGATGAACGCGTTCATCAAGTGCGAGGGCGGCGGCTATGACTACGATAATCCCGAGCAGTACCGGCCGCTGCTCACCCGCGACAAGGTGGAGTTCATCGAGCAGAACGACGAGTTCCTGGAGCAGTACCAGACGATGACCTGCCGCTGCTGCAGCAAGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGCTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCATCTGAAGAAGCGCAACTGCATCAATCTCTTCAGGGTGCTCAATGCGCTGCGTGGCAAGACAACGGCCGTGGTGGTGCCCTCCATCACCGATGATGTGGCCGACGATGGCGCAGGAGTCGTGGCGGTGGCCGATGCCGGCGCTGGCGTGGTGCTCACCATGACCAGTCCCACGGTGACAGTGGGCGGCGGCGGAGAGGCCCTCACTCCCGGCGGTGGCTCCGAGCGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTCAACAAGCTGTACGAGTGCAAGCTCTGTCCCAAGGGCTTCCGCACCAAGCACGAGTTCCGCACGCATGTGTACGACAAGCATGCGGACGTCCAGCGCAAGGACAACAACTCGATACAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCGGTGGACAGGCGGCGGCACTACAACAACATGGACTGTATCGTTCGGCTGCGCTGCATGACGTGCGATGCCAAGCTAGAAACGCACCAGCGGTTCCTGGACCATGTCTACCAGGATCACCTGGGCGGCGTGGGTGGCGGCGGGGCGAGCAGCGATAATGCCTCCACCACGGGCAGTGGCATGGCCAGGAGCAACAGCATGGAGCATTCGCCGGGCAAGAGGAGTCTGCTGGGGGCCCTGGGCATTGGCGTTGGCTCCTCGGCGGATGAGTCGCGTAGCAGCAGTGCCGCTCCGCCGCTGACCTCCACACCCAAGCCGACGGGAGTCGTCCAAGTGGGTGGCGGGGGCAGTGTCAGCGGTGGCGGCGGCTTGGCCAGCGCCTCGGCCTCCGCGCAGAGCTCGGCCAACCGAGATGCGTCCGCACCCAAGTCGCAGTACTTCTCCCGCATGCCGCAGGTCTGCCCCATTTGCGGCCAGCAGTACAACAACTACAACAACGTGCTGCGCCACATGGAATCGAAGCATCCGAACAAGCTGCCCGAGACGTACAAGTGCGTGCGCTGCGGCCTGGGCTATCCCCGGATCTCCTATCTGCGGGAGCACATGATCAACGTGCATGGCGTGGACAAGAACCGGCACTCGGGCGGCTTCGAGTACATCGTGAATGCGGACGCCGTCAAGTTGGCCGACGGCAGCACGCCGAACGTCTACACGGGTCGCTACGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACACTCGATGACGAGGAGGAGGAGCCGGGCAGCGTGGCCAAGAAGATGCGCCTGGACGACAGCAGCAACAACAGCAGCCTGGTGGGCGTGGCCAGCCAGCAGAAGGAGTGCCCCATCTGCAATGCGGTGTTCAGCAACAACATCGGCCTGTCCAATCACATGCGCTCCCACTACACGGCCTCCAATGCCGTGAATGCCGCCCTGGCGGCTGCCAATCGCATGACACCCAAATCGCTGACCATAACCGCACAACCAGCCGGAGACTCGGACGGGGGCATGGTGGCCAGTGCATCGGTTACGGCCCCAGCCACGCCGGCCAATGTGCCACCGGCCATGGCCAACCAGACGCCGCAGGAGCAGGCCGTGTTCCGGCGCAGCCTCGACCAGGCGGCGGACCGCCGCTTCCGGCGCATGCGCTGCCGCATTTGCCAGCGGCGCTTCAGCTCGAAGAAGTCCTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCCGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGCAGGGCCATTAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGAGGTCTGCTCCATTGTCTACAGCTCGGAGCTGGAGCTGGCGCAGCACAAGCGCAGCGTTCACAAGCTGGCCTCTGCCTCCGCCTCGGCCTCCACGTCGGCGTCCACTTCCTCCAAGATCGACGATGACTTGCTGATGGACGAGGCCAAGCCCACGGCAGCGGATCTGGCCGATCTCTCCACCCTGGCGGCGAGTGCCTCAGCGGCCTCGGCTTCGGGCCAGGTCCTGGGCACGCCGCTGTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAACGATTACTCCTGCAAAGACTGCGGCAACGTGTACAGCGGCCGCAAGAGTCTGTGGGTGCATCGCTACAAGAAGCATCCGCAAGTGCCCGACCCGGCCGAGTGCTCGCTGTGCCGCAAGGTCTTCTTCGACCGGCAGATGCATGACAACCACACGCCCACCTGCAACCGCAAGCCGATCACTTCGACCGGTGCCCACCAGCAGCAGGATGCGCAGCTGCAGCAGCAGCAGCAGGCGTCTCTCCAGCTGGCCAGGCGCACTGTGTTCCGGCACAAGACGGGCGACGACGAGGACGATGACCAGGAGGACGATGACCAGCAGCAGCAGCAGCTGGAGGAGCGGGCCAGTGCGGATGGCAATGGAACGGTGGCCTCGGGCAGTGTGGTGGCGGCGGCCACGTCGCTCAAGATACGCATACCCGAGGTGGCGTGCACCATTTGCGGGGCCCGCTTCACCGACCAGGAGCACTTCAGCAAGCACATACAGAAGCATGAGCAGGAGCTGTACGTGGACAATCCGCTGGCGGCGATGTTCGACGATGGGCCGGCGGATGCGGGGCAGTTCCAGGTGGAGCGGCAGAACGAGAACGGGGAGTACGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATCGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACATAACAACAATCTGCGTCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCGGAGCCGCCGGTGATTGTGGTCGACGACCATCTGACCTGCCGGCGCTGTCAGCTGACGTTCGACACCAAGGAGCTGTGGATCGAGCACAAGCTGGCCGACGCCAAGGTGGTGCGACCCTTCTGCCCCTTCCAGTGGGGCTGCGACCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAACCACATCAACAACCATCTCAAGGAGGAGGTCATCGTGCCGGTGGCCACCAAGGCGGCCATAGAGAGGACAGCGGCCATGGCGGCGGCGTCGGCAGCGGATGCAAGCACAGCGGCGACGGCGCCATCAACAGGATTGGATGAGGCAGCCAAAGCGGAGGAGCAAGCTCTGGAGAAGGGTGAGGTGGCGGCAGCAGCAGGTGCAGGAGGAGCGGCAGCAGCAGCAGAGAAGATGGAGGAAGATAGCGATGACCTGGACGAGGATGATAGTTCGGGCGAGGAGGAGGAAAGCTCGGGCACGGGCGACGATGAGGACGACGACACGGACGATGAGGACGGCGAGGGTGAGGATGAGGACGAGGACGAGGAGGGCGACGGCGGCGAGGGCGAGGACGAGGAGGGTGTGCAGCCGCCGGCTCAACTGTTGCCGCCACAGAAGCAGCACAAAGCGGATCTTAACCCGGATGACGATGATCTCGAGCCGGAGCCAGTGGCAATGCCGGTACGACCGCTGATGAATGGCAAGTCGAAGATTCCGCCACTGATCGTGGCCAGTTCGGATGAGGAGGACGATGGTGTGATACCCATCGAGGACATCATCGAAGAGGAGTTCGATGAGGATGCCGATCCGGATCCCGATCCGGAGGATGCCATCGAGGAGGTGGACGACGATGATTTAGATGAGGGCGATGCGGAGGACGAGCCGAATGTGGTGTCGACGGCCTCCTCCTCGGAGAGCGAGTCCACCACAACGACCACGTCCAATTCGCACTCGCACTCGCATTCGCATACGCATTCCACGGGTGAGCGGCGCCAGAAGCCGGCGGATCAGTCGAATGATCCCGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTCCAGAGCCACATCAAAAGCCATATCCTCAATGGGCCAAAGCTCTCGACAGCGGCCGGCCAGCCGCCAGTGGCCACGACAGCAGTCGCCACCGCCACAGTGGCAGCGGCAACAGCGGGCGTCGCGGCGGCAGCAGCATTGGCAACGGCAGCAAAGACGAAGCCTGACTCCAAGTCGGCGGCGCTGGCCAACAATAACAACAACAAGAGCAAGACTGTGGCAACAGCTGCCAAAGCTGCCACAGCTGCCACGACAAATTGA
Protein Sequence: MRTHCYQSQQDISYDLRSVLRPWWGAAEGGSGRWADGKITPQDRLSLQICHACISYLNSWQSFKNRCFSSQTKQRQWLDPKLFMPLDIAVPPLPPLPPVAPVSIAPPAGAAELLPGMSGVGGMESLSLSLPLDFSQGCSSSSGHVQQQQQQAAGGLVTATSTSNAPGSVVSATATASVSGSASASAAACATASAASASATATASASVSTAPLLMPPLPAIPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDVPLTASDYDYTAQHGVNASSVAASLPANAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAAAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYDNPEQYRPLLTRDKVEFIEQNDEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLFRVLNALRGKTTAVVVPSITDDVADDGAGVVAVADAGAGVVLTMTSPTVTVGGGGEALTPGGGSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGGASSDNASTTGSGMARSNSMEHSPGKRSLLGALGIGVGSSADESRSSSAAPPLTSTPKPTGVVQVGGGGSVSGGGGLASASASAQSSANRDASAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEEPGSVAKKMRLDDSSNNSSLVGVASQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITAQPAGDSDGGMVASASVTAPATPANVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSELELAQHKRSVHKLASASASASTSASTSSKIDDDLLMDEAKPTAADLADLSTLAASASAASASGQVLGTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKVFFDRQMHDNHTPTCNRKPITSTGAHQQQDAQLQQQQQASLQLARRTVFRHKTGDDEDDDQEDDDQQQQQLEERASADGNGTVASGSVVAAATSLKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATHNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLTCRRCQLTFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKAAIERTAAMAAASAADASTAATAPSTGLDEAAKAEEQALEKGEVAAAAGAGGAAAAAEKMEEDSDDLDEDDSSGEEEESSGTGDDEDDDTDDEDGEGEDEDEDEEGDGGEGEDEEGVQPPAQLLPPQKQHKADLNPDDDDLEPEPVAMPVRPLMNGKSKIPPLIVASSDEEDDGVIPIEDIIEEEFDEDADPDPDPEDAIEEVDDDDLDEGDAEDEPNVVSTASSSESESTTTTTSNSHSHSHSHTHSTGERRQKPADQSNDPGFTCDLCQLCFDSQELLQSHIKSHILNGPKLSTAAGQPPVATTAVATATVAAATAGVAAAAALATAAKTKPDSKSAALANNNNNKSKTVATAAKAATAATTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512163; iTF_00565540; iTF_00548215; iTF_00607900; iTF_00536927; iTF_00581681;
90% Identity: -
80% Identity: -