Basic Information

Insect: Drosophila mimetica
Gene Symbol: hang
Assembly: GCA_037075245.1
Location: JBAMCH010000005.1:8495501-8506190[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.33 25 5.7 1.0 3 23 505 526 504 526 0.93

2 19 1.1 82 4.1 3.1 3 22 634 653 632 653 0.89

3 19 0.00071 0.054 14.1 3.3 1 22 728 749 728 751 0.90

4 19 0.081 6.3 7.6 0.1 2 21 763 782 762 783 0.93

5 19 0.00082 0.063 13.9 0.2 2 23 923 945 922 945 0.95

6 19 0.0024 0.18 12.5 0.1 1 23 953 976 953 976 0.96

7 19 1.9e-05 0.0015 19.0 0.1 2 23 1061 1082 1060 1082 0.97

8 19 0.00034 0.026 15.1 2.9 2 23 1166 1188 1165 1188 0.97

9 19 0.027 2 9.2 0.2 2 23 1197 1219 1196 1219 0.95

10 19 0.0025 0.19 12.4 0.1 1 23 1232 1255 1232 1255 0.97

11 19 0.00015 0.011 16.3 1.1 1 23 1317 1339 1317 1339 0.99

12 19 0.0023 0.18 12.5 0.9 1 23 1347 1370 1347 1370 0.96

13 19 9.9 7.6e+02 1.1 0.2 2 13 1378 1389 1378 1391 0.85

14 19 3.8e-05 0.0029 18.1 1.4 3 23 1487 1507 1486 1507 0.98

15 19 0.0059 0.46 11.2 0.1 1 23 1542 1564 1542 1564 0.97

16 19 0.0007 0.054 14.1 0.6 2 23 1653 1675 1652 1675 0.93

17 19 1.5 1.2e+02 3.6 0.1 2 20 1695 1713 1694 1715 0.91

18 19 0.0078 0.6 10.8 0.4 3 23 1730 1750 1730 1750 0.98

19 19 0.00012 0.0092 16.5 2.1 1 23 2061 2083 2061 2083 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.33	25	5.7	1.0	3	23	505	526	504	526	0.93
2	19	1.1	82	4.1	3.1	3	22	634	653	632	653	0.89
3	19	0.00071	0.054	14.1	3.3	1	22	728	749	728	751	0.90
4	19	0.081	6.3	7.6	0.1	2	21	763	782	762	783	0.93
5	19	0.00082	0.063	13.9	0.2	2	23	923	945	922	945	0.95
6	19	0.0024	0.18	12.5	0.1	1	23	953	976	953	976	0.96
7	19	1.9e-05	0.0015	19.0	0.1	2	23	1061	1082	1060	1082	0.97
8	19	0.00034	0.026	15.1	2.9	2	23	1166	1188	1165	1188	0.97
9	19	0.027	2	9.2	0.2	2	23	1197	1219	1196	1219	0.95
10	19	0.0025	0.19	12.4	0.1	1	23	1232	1255	1232	1255	0.97
11	19	0.00015	0.011	16.3	1.1	1	23	1317	1339	1317	1339	0.99
12	19	0.0023	0.18	12.5	0.9	1	23	1347	1370	1347	1370	0.96
13	19	9.9	7.6e+02	1.1	0.2	2	13	1378	1389	1378	1391	0.85
14	19	3.8e-05	0.0029	18.1	1.4	3	23	1487	1507	1486	1507	0.98
15	19	0.0059	0.46	11.2	0.1	1	23	1542	1564	1542	1564	0.97
16	19	0.0007	0.054	14.1	0.6	2	23	1653	1675	1652	1675	0.93
17	19	1.5	1.2e+02	3.6	0.1	2	20	1695	1713	1694	1715	0.91
18	19	0.0078	0.6	10.8	0.4	3	23	1730	1750	1730	1750	0.98
19	19	0.00012	0.0092	16.5	2.1	1	23	2061	2083	2061	2083	0.98

Sequence Information

Coding Sequence: ATGGAGACGGAGTTGGAGTTGGACATCCTGCACTGGGAATGGGGCATTGTACATAAGGATACGGCAATCACACCACAGGATCGGCTGTCGCTCCAGATTTGCCACGCCTGTATCAGCTACCTGAACTCATGGCAGAGCTTCAAGAACCGATGCTACAGCTCGCAGACGAAGCAACGCCAGTGGCTGGATGCCAACAAGAGCAAGCTCCTCAGCTACCTGGACCTGAATAGTGCGGAGAATGGAGGAGGAGGCTCCTACgatcaccagcagcaggcgcaacaacaactgcatcagcagcaacagcaacagcaatcggAGAATGAGCTCGAAGCGGAGAAGGCGACGCCAACGGCCACAACGACGGCCGCCAACATTTTGGATGGCATACACTCGCTGAAGAAACGCAAATCCCTAACAGTCTATGTGAGTCCTAAACCGCAGCAGCTGCCACAGCATCAattgcagcagttgcagctgcaaccACCGGCCAGAATGACGGCGACGACCAGCAACGCGCAGCAATCGCTGCAGACCCTTCTCTTGCAGGTTCCACCAcctgcggcggcggccagctgctcctccacaTCCACAACCACgtccacatccgcatcccaGCAGcgggaacagcagcagcatcagcaccaGCAGCGTCAGCAATCTCATCAATATCGCAGataccatcatcatcaccaccagcagcatcagcagcaccagcagcagcggggCAAGCACATGTtgccccatcatcatcatcagcagcagcagcatcagcaacagccGCATCAGCATAGACGCCAGCGGCAATTTCGTCCACAGCGTCCAGTGCCGCCGGTGGCAAATCCGGCTCCATCGTTGCGAAAATTCAAACCGAAGCTGTATTTGCCATTGGACATAGCAGTGCCTCCACTGCCGCCGCTGCCAATGCCACCTGTGCCGCCAGTGGCAACCACCGGATCGATTGCTCCGCCGgcttctgctgccgctgctgctgctgaactGCTGCCCGGGTTGTctggtgtgggtgtgggtggaaTGGAGAGCttgtcgctgtcgctgccgCTTGATTTCAGCcaaagctgcagcagcagcagtcacgtccagcaacagcaggcggcTGGTGGCCTGGCCACGACGACGTCCACGTCCAATCCGCCGGGCAACGTCGTTTCCGCCACGGTCTCTGCctctgcaactgcaactgcatctgcatctgcttCTGCGTCTGCTTCCACGGCTCCGCTGCTTATGCCGCCACTGCCTGCGATTCCCATCAAAGATGAGCCCATTGACACGGATGACGACTACCAGATGAAGTCGATAGACGAGTCTGATGACATGGTCGATCCCACAATGTTCCTAGAGCGTTCCGAGCACGAGGGCGATATGCCGCTGACGGCCTCGGACTACGACTATACTGCCCAGCATGGCGTGAATGCCTCGTCCGCAGCCGCCTCGCTGCCGGCGAATGCGGTGGCCAATGTGGCAGCCGCCGGGGACTCAAAGGTGGCCAGTTGCCGGGCATGCAGTCTGCAGTTCTCCACCCGGGCCAACGCCCGTCGCCACGAACGGAATCTGCACCCCAATCTGTTCCAGCTGTCCACCGACTCGCCGCACAACACGCCCATCACGAAGCCAACGCCCGCCCTTGCCGCCGCCCTGGAGATCCAACGGGCAGCAGCTGCGGCGGCCACGGCGGAGGCAAATCGAGCTGCGGGAGCGGCGGGCGGTAATATCTCAACGCAAAAGTATCGCCAGGTCGTGATGAACGCGTTCATTAAGTGCGAAGGCGGTGGCTATGACTACGATAATCCCGAACAGTATCGATCGCTGCTCACCCGCGACAAGGTGGAGTTCATCGAGCAGAACGACGAGTTCCTCGAGCAATACCAGACGATGacctgccgctgctgcagcaaGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTACGCAAGAAGTATCCGCTGCTGCCGCGCAACCTGTGCTTCAATTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATCTCGCATCTGAAGAAGCGCAATTGCATAAATCTCTTTAGGGTTTTGAATGCACTGCGCGGCAAGACAACGTCAGCAGTGGTCCTAGCCACAGCAGAGGATGAGGCGATGGACGATAAACTGCGCGCCAAGGAGCTGCTGGTCAACAAGCTGTACGAGTGCAAGCTCTGCCCGAAGGGATTCCGCACCAAGCACGAGTTTCGCACGCATGTGTACGACAAGCATGCGGATGTTCAGCGCAAGGACAACAACTCGATACAGTGCAGCTTCTGCGGACTGGACTTTGCCGATCCGGTGGACAGGCGGCGGCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACGTGCGATGCGAAACTGGAGACGCATCAGCGATTCCTCGACCATGTCTACCAGGATCACTTGGGCGGCGTGGGTGGCGGCGGAGCGAGCAGCGATAATGCCTCAACCACCGGCAGCGGCATGGCCAGGAGCAACAGCATGGAGCACTCGCCGGGCAAGAGGAGTCTGCTCGGTGCTCTGGGCATTGGTGTCGGCTCCTCGGCGGATGAGTCGCGTAGCAGCAGTGCAGCGCCTCCGCTGACCTCGACACCGAAACCTGCGGGAGCTGCTCAGatgggtggcggcggtggaggcggCGGCTCAACCAGCGCCTCAGCCTCCGCACAGAGCTCAGCGAATCGAGATGCGTCCGCCCCGAAATCCCAGTACTTCTCCCGGATGCCGCAGGTCTGCCCCATTTGTGGCCAGCAgtacaacaactacaacaacgtGCTGCGACACATGGAATCGAAGCATCCGAATAAACTGCCAGAGACCTACAAGTGCGTGCGATGCGGACTGGGCTATCCGAGGATCTCGTACCTGCGGGAGCATATGATCAATGTGCATGGCGTGGACAAGAACCGTCACTCGGGCGGCTTTGAGTACATCGTGAATGCGGATGCAGTGAAGTTGGCAGACGGAAGCACGCCGAACGTGTACACGGGTCGCTACGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACACTCGATGACGAAGAGGAGGAGCCGGGCAGCGTGGCCAAGAAGATGCGCCTggacgacagcagcaacaacagcagcctggtgggcgtggccagccAACAAAAGGAGTGCCCCATCTGCAATGCGGTGTTCAGCAACAACATTGGCCTCTCCAATCACATGCGCTCCCACTACACAGCCTCGAATGCAGTAAATGCCGCTCTGGCGGCCGCCAATCGAATGACACCCAAATCGTTGACAATTAccgcaacaccagcagcagctgattCCGAGCTGGGACTGGGGGTAACCGCATCGGTGTCTGCCCCAACAACACCCGCAGCCAATGTGCCACCGGCCATGGCCAATCAGACGCCCCAGGAGCAGGCCGTATTCCGGCGAAGTCTCGACCAGGCGGCCGATCGTCGCTTCCGTCGAATGCGCTGCCGCATTTGCCAGCGCCGCTTCAGCTCGAAGAAATCCTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCAGAGTTTGCCTACGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGCAGGGCGATCAAGGACGAGATGATTATCAAGCAGTTTGAGTGCGAGGTCTGCTCGATTGTCTACAGTtcggagctggagctgcagcagcacaagCGCAGCGTTCACAAGCTGACCTCTGCCTCCGGATCGGCATCCACTTCGGCGTCCACCCCCTGCAAGATTGACGATGACTCGCTGATGGACGAGGCCAAGCCCACAGCAGCGGATCTGGCTGATCTCTCAACGCTCGCGGCCAGTGCGTCCACGGCATCGGCTTCGGGTCAGGCACTGGGCACACCGCTGTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATACACATCAACTCGCACGACGAGTTCGACTCGAACGATTATTCCTGCAAAGATTGCGGCAACGTCTACAGCGGACGCAAGAGTCTATGGGTGCATCGCTACAAGAAGCATCCGCAAGTACCCGATCCAGCCGAGTGCTCGCTGTGCCGCAAGGTCTTCTTTGACCGCCAGATGCATGACAACCATACGCCCACTTGCAACCGCAAGCCGATCACATCGACGGGtgcccaccagcagcaggatTCGCAGCAACAGGCGTCGCTTCAGCCGGCCAGACGAACCGTTTTCCGGCACAAGACCGGCgatgacgaggacgaggaggaggacgatgaccagcagcagcagcagttggagGAGAGGGCAATAATGGACGGTGATGGCAATGGGACGGCATCGGGAAGTGCGGTGACTGTGACGGCGGCGGCACCGTCGCTAAAGATCCGCATTCCGGAGGTGGCTTGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGCACTTTAGCAAGCACATCCAGAAGCACGAACAGGAGCTGTACGTGGACAATCCACTGGCGGCGATGTTCGATGATGGGCCAGCGGATGCTGGCCAGTTCCAGGTGGAGCGGCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATCGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCAtacaaccaacaacaacaacaactcgaTGCTGCACCTCCGCGAGCTGCATGCGGTGGGCCTGATGcccaaccagcagcagcagcagcaacagcagagcCTCAACAACtcgtgcaacagcagcagcatgaaccacaacaacaacaacagcagcagcagcagcagcaaccgcagCAAATCAATGAAGCGGAAACGTGAGCTGAAATGCGAATACTGCGCCTCCACCTTCATCAGTAACAACAATCTGCGTCGCCACATGTACGAGCTGCACAAGCACGAGGTAAGCAATCTGCCCGAACCACCGGTGATTGTGGTGGACGATCACCTCACCTGCCGTCGCTGCCAGATGAAGTTTGAAACGAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCCAAGGTGGTGCGACCCTTCTGCCCCTTCCAATGGGGCTGCGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAATCACATTAACAACCATCTCAAGGAGGAGGTCATCGTGCCAGTGGCCACCAAGGCGGCCATTGAGCGGACAACGGCCATGGAGgcggcgacagcagcagcagcagcagatgcaacCACATCGGTGCCATCGATAGCATTGGGTGAAGCAGTAGAAACGGAGGAGCAATCTCTGGAGAAAGGTGAGgtagcagcaacagcggcagcagcagcaacagtaggCGAGAAGTTGGCGAGACCCGAGGAAGAAGACAGCGATGATCTGGATGAGGATGATAGCTCGGGCGAAGAGGAGGAGAGTTCAGGTACGGgagatgatgacgatgacgacgaggaCACCGACGACGAGGATGGCGAGGGTGAAgatgaggacgaggagggAGATGGGGGCGAAGGCGAAGACGAGGAGGGTGTCCAGCCACCGGCTCAGCTGTTGCCACAGAAGCAACACAAAGCGAATCTTAACCAGGATGACGACGATCTCGTCGAGGAGGTTATCAGCTCGGATGACGATGAAGAAGATGATGGCGTGGTGGAGagcgacgatgacgacgatgatgaagAGGACGATGAGGAGGACGATGTTGAAGAGCCGGAGCCAGTTGGATTGCCGGTGCGACCGCTAATGAATGGCAAGTCCAAAATGCCACCGCTGATTGTGGCCAGCtccgaggatgaggatgatggTGTGATGCCCATCGAGGACATCATCGAGGAGGAGTTCGATGAGGATGCCGATCCAGATCCAGAGCCGGAGGATGCCATCGAGGAAGAGGTAGACGACGATGATTTAGATGAGGGGGATGTGGAGGACGAGCCGAATGTGGTGTCGACGGCCTCCTCATCGGAGAGCGAGTCCACCACAACGACCACGTCCATTTCGCATTCACATTCGCATTCCACGGGTGAGCGGCGTAAGAAGGCCGACGATCAGTTGAATGATCCCGGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTCCAGAGCCACATCAAAAGCCATATCCTCAATGGGCCAAAGCTctcaacagcggcagcagcagcagcagcagcaacaacaacacagccagcggcagcagcaacagcaggagcGACCGCAAGCAacgcggcagcaacagcaacaacaacattaacggcaacggcagcaaAGACGAAGCCTGACTCCAAGTCAGCGGTGCTggccaacaataacaacaacaaaagcaaggCTGTTGCTGCCAcggcaacaactgcaacagtTGCGACAAATTGA
Protein Sequence: METELELDILHWEWGIVHKDTAITPQDRLSLQICHACISYLNSWQSFKNRCYSSQTKQRQWLDANKSKLLSYLDLNSAENGGGGSYDHQQQAQQQLHQQQQQQQSENELEAEKATPTATTTAANILDGIHSLKKRKSLTVYVSPKPQQLPQHQLQQLQLQPPARMTATTSNAQQSLQTLLLQVPPPAAAASCSSTSTTTSTSASQQREQQQHQHQQRQQSHQYRRYHHHHHQQHQQHQQQRGKHMLPHHHHQQQQHQQQPHQHRRQRQFRPQRPVPPVANPAPSLRKFKPKLYLPLDIAVPPLPPLPMPPVPPVATTGSIAPPASAAAAAAELLPGLSGVGVGGMESLSLSLPLDFSQSCSSSSHVQQQQAAGGLATTTSTSNPPGNVVSATVSASATATASASASASASTAPLLMPPLPAIPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDMPLTASDYDYTAQHGVNASSAAASLPANAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAAAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYDNPEQYRSLLTRDKVEFIEQNDEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLFRVLNALRGKTTSAVVLATAEDEAMDDKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGGASSDNASTTGSGMARSNSMEHSPGKRSLLGALGIGVGSSADESRSSSAAPPLTSTPKPAGAAQMGGGGGGGGSTSASASAQSSANRDASAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEEPGSVAKKMRLDDSSNNSSLVGVASQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPAAADSELGLGVTASVSAPTTPAANVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSELELQQHKRSVHKLTSASGSASTSASTPCKIDDDSLMDEAKPTAADLADLSTLAASASTASASGQALGTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKVFFDRQMHDNHTPTCNRKPITSTGAHQQQDSQQQASLQPARRTVFRHKTGDDEDEEEDDDQQQQQLEERAIMDGDGNGTASGSAVTVTAAAPSLKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTNNNNNSMLHLRELHAVGLMPNQQQQQQQQSLNNSCNSSSMNHNNNNSSSSSSNRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLTCRRCQMKFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKAAIERTTAMEAATAAAAADATTSVPSIALGEAVETEEQSLEKGEVAATAAAAATVGEKLARPEEEDSDDLDEDDSSGEEEESSGTGDDDDDDEDTDDEDGEGEDEDEEGDGGEGEDEEGVQPPAQLLPQKQHKANLNQDDDDLVEEVISSDDDEEDDGVVESDDDDDDEEDDEEDDVEEPEPVGLPVRPLMNGKSKMPPLIVASSEDEDDGVMPIEDIIEEEFDEDADPDPEPEDAIEEEVDDDDLDEGDVEDEPNVVSTASSSESESTTTTTSISHSHSHSTGERRKKADDQLNDPGFTCDLCQLCFDSQELLQSHIKSHILNGPKLSTAAAAAAAATTTQPAAAATAGATASNAAATATTTLTATAAKTKPDSKSAVLANNNNNKSKAVAATATTATVATN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486721;
90% Identity: iTF_00578694; iTF_00581681; iTF_00536927;
80% Identity: -