Basic Information

Insect: Drosophila lutescens
Gene Symbol: hang
Assembly: GCA_037075285.1
Location: JBAMCF010000051.1:400810-410994[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.34 28 5.7 1.0 3 23 509 530 508 530 0.93

2 17 1.1 89 4.1 3.1 3 22 638 657 636 657 0.89

3 17 0.00073 0.059 14.1 3.3 1 22 777 798 777 800 0.90

4 17 0.085 6.8 7.6 0.1 2 21 812 831 811 832 0.93

5 17 0.00085 0.069 13.9 0.2 2 23 973 995 972 995 0.95

6 17 0.0024 0.2 12.5 0.1 1 23 1003 1026 1003 1026 0.96

7 17 2e-05 0.0016 19.1 0.1 2 23 1111 1132 1110 1132 0.97

8 17 0.00035 0.028 15.1 2.9 2 23 1216 1238 1215 1238 0.97

9 17 0.028 2.2 9.2 0.2 2 23 1247 1269 1246 1269 0.95

10 17 0.0026 0.21 12.4 0.1 1 23 1282 1305 1282 1305 0.97

11 17 0.00015 0.012 16.3 1.1 1 23 1371 1393 1371 1393 0.99

12 17 0.0024 0.19 12.5 0.9 1 23 1401 1424 1401 1424 0.96

13 17 3.9e-05 0.0032 18.1 1.4 3 23 1539 1559 1538 1559 0.98

14 17 0.0062 0.5 11.2 0.1 1 23 1594 1616 1594 1616 0.97

15 17 0.00073 0.058 14.1 0.6 2 23 1705 1727 1704 1727 0.93

16 17 3.9 3.1e+02 2.4 0.1 2 20 1747 1765 1746 1767 0.91

17 17 0.0081 0.65 10.8 0.4 3 23 1782 1802 1782 1802 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.34	28	5.7	1.0	3	23	509	530	508	530	0.93
2	17	1.1	89	4.1	3.1	3	22	638	657	636	657	0.89
3	17	0.00073	0.059	14.1	3.3	1	22	777	798	777	800	0.90
4	17	0.085	6.8	7.6	0.1	2	21	812	831	811	832	0.93
5	17	0.00085	0.069	13.9	0.2	2	23	973	995	972	995	0.95
6	17	0.0024	0.2	12.5	0.1	1	23	1003	1026	1003	1026	0.96
7	17	2e-05	0.0016	19.1	0.1	2	23	1111	1132	1110	1132	0.97
8	17	0.00035	0.028	15.1	2.9	2	23	1216	1238	1215	1238	0.97
9	17	0.028	2.2	9.2	0.2	2	23	1247	1269	1246	1269	0.95
10	17	0.0026	0.21	12.4	0.1	1	23	1282	1305	1282	1305	0.97
11	17	0.00015	0.012	16.3	1.1	1	23	1371	1393	1371	1393	0.99
12	17	0.0024	0.19	12.5	0.9	1	23	1401	1424	1401	1424	0.96
13	17	3.9e-05	0.0032	18.1	1.4	3	23	1539	1559	1538	1559	0.98
14	17	0.0062	0.5	11.2	0.1	1	23	1594	1616	1594	1616	0.97
15	17	0.00073	0.058	14.1	0.6	2	23	1705	1727	1704	1727	0.93
16	17	3.9	3.1e+02	2.4	0.1	2	20	1747	1765	1746	1767	0.91
17	17	0.0081	0.65	10.8	0.4	3	23	1782	1802	1782	1802	0.98

Sequence Information

Coding Sequence: ATGGAAATCCTTGTATCCTGTATCCAATTGCACGGGGGAAACATGGCGGCCATAAAGGAAACGCTGGTTTGGATTACACCGCAGGATCGACTGTCGCTCCAAATTTGCCACGCCTGCATCAGCTACCTGAACTCATGGCAGAGCTTCAAGAACCGATGCTTCAGCTCACAGACGAAGCAGCGCCAGTGGCTGGATGCCAACAAGAGCAAGCTCCTCACCTACCTGGACCTGAACAGTGCGGAgaatggaggaggaggcgaaggaggaggaggaggttcCTACgatcaccagcagcagcagcaacaacaacagcagcagcaacagcaatcgGAGAATGAACTCGATGCGGAGAAGGCGACGCCAACGGCCACAGCAACGGCCGCCAACATTTTGGATGGCATACACTCGCTGAAGAAACGCAAATCCCTAACAGTCTATGTGAGTCCTAAACCGCAGCAGCTGCCACAGCATCAATtgcagcagttgcagctgcaacCACCGGCCAGAATGACGGCGACGACCAGCAGCAACGCGCAGCAATCGCTGCAGACCCTTCTCTTGCAGGTGCCAGCatctgcggcggcggcggcggccagctgctcctccacGTCCACATCAACCACATCCGCATCCCACcagcgggagcagcagcatcagcagcgtCAGCAATCTCATCAATATCGCAGGTACCAtcatcaccaccaccagcagcagcatcagcagcaacatcagcagcagcgtGGCAAGCAAATGTTgccacatcatcatcatcagcagcagcagcaacagcagcatcagcataGACGCCAGCGGCAATTTCGTCCACAGCGTCCAGTTCCGGTGGCAAATCCGGCTCCATCGTTGCGCAAATTCAAACCGAAGCTGTACTTGCCGCTGGACATAGCAGTGCCTCCACTGCCACCGCTGCCAACGCAGCCATCTTTGCCACCAGTGGCCACCGCCGGATCGATtgctgcgcctgctgctgccgctgaaCTGCTGCCCGGGATGTctggtgtgggtgtgggtggtgGATTGGAGAGCTTGTCGCTGTCGCTGCCGCTTGATTTCAGCcaaagctgcagcagcagcagcgtcgGTCACGTCCATCAACAGCAGCCGACGGCGATGGCCACGACGACGTCCACGTCCAATCCGCCGGGCAACGTCGTTTCCGCCACGGCCTCTGTCTCTGCATCTGCAACTGCATCGGCAAACGCATCTGCTTCCGTGTCTGCTCCCACGGCTCCGCTGCTTATGCCGCCACTGCCCGCGATGCCCATCAAAGATGAGCCCATCGACACGGATGACGACTACCAGATGAAGTCCATTGACGAGTCTGATGACATGGTCGATCCCACGATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATATGCCGCTGACGGCCTCGGACTACGACTATACTGCCCAGCATGGCGTGAATGCCTCGTCCGCCGCAGCCTCGCTGCCGCCGAATGCGGTGGCCAATGTGGCAGCCGCCGGCGACTCCAAGGTGGCTAGCTGCCGGGCCTGCAGCCTGCAGTTCTCCACCCGGGCCAACGCCCGTCGCCACGAACGCAATCTGCACCCCAATCTTTTCCAGCTGTCGACAGACTCGCCACACAACACGCCCATTACGAAGCCAACGCCCGCCCTGGCTGCCGCCCTGGAGATCCAACGGGCAGCGGCTGCGGCGGCCACTGCGGAGGCAAATCGAGCTGCGGGTGCGGCGGGCGGCAATATCTCGACGCAAAAGTATCGCCAGGTGGTGATGAACGCGTTCATCAAGTGCGAGGGCGGCGGCTATGACTACGATAATCCCGAACAGTATCGATCGTTGCTCACCCGCGACAAGGTGGAGTTCATCGAGCAGAACGACGAGTTCCTCGAGCAGTACCAGACGATGAcctgccgctgctgcagcaAGTACTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGCTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATCTCGCATCTGAAGAAGCGCAACTGCATAAATCTCTTTAGGGTTTTGAATGCGCTGCGTGGCAAGACGACGGCAGCAGTGGTTCTATCCTCGGCCGAGGATGTGGCGATGGACGATGGGGCAACCGGAGTCGTTGCTATTCCCGATCAGGATGTTTTAGCAGGAGCCGGAGCCGGTGTGGTGACCATGACCAGTCCAACAGTGACGCCCGATGTCGTCACTCCCGGTGGTGGTGGCTCTGAACGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTCAACAAGCTGTACGAGTGCAAGCTCTGTCCGAAGGGATTCCGGACCAAGCACGAGTTCCGAACGCACGTGTACGACAAGCATGCGGATGTCCAGCGCAAGGACAACAACTCCATACAGTGCAGCTTCTGCGGACTGGACTTTGCCGATCCGGTGGACAGGCGGCGGCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACGTGCGACGCGAAGCTGGAGACGCATCAGCGGTTCCTCGATCACGTCTACCAGGATCACTTGGGCGGcgtgggcggcggcggcggcggggcGAGCAGCGACAATGCCTCCACCACGGGCAGCGGAATGGCCAGGAGCAACAGCATGGAGCATTCGCCGGGCAAGAGGAGTCTGCTCGGTGCCTTGGGCATCGGTGTTGGCTCCTCGGCGGATGAGTCGCGTAGCAGCAGTGCGGCTCCTCCGTTGACCTCTACACCAAAGCCGGCGGGAGCTACCCAAGtgggtggcggcggcggcggcggctcaACCAGCGCCTCAGCCTCCGCACAGAGCTCGGCGAATCGAGACGCGTCCGCACCGAAATCCCAGTACTTCTCCCGGATGCCGCAGGTCTGCCCCATTTGCGGCCAGCAgtacaacaactacaacaatgTGCTGCGGCACATGGAATCGAAGCATCCCAACAAACTGCCCGAGACATACAAGTGCGTGCGATGCGGATTGGGCTATCCAAGGATCTCCTACCTGCGGGAGCATATGATCAATGTGCATGGCGTGGACAAGAACCGACACTCCGGAGGCTTTGAGTACATCGTGAATGCGGATGCAGTGAAGTTGGCCGACGGCAGCACGCCGAACGTTTACACGGGTCGCTACGACTACGTGATGAAGGACCTGATGTCGATAACAAATGGTGGGACACTCGATGACGAAGAGGAGGAGCCGGGCAGCGTGGCCAAGAAGATGCGGCTggacgacagcagcaacaacagcagcctgGTGGGTGTGGCCAGCCAACAGAAGGAGTGCCCCATCTGCAATGCGGTGTTCAGCAACAACATTGGCCTCTCCAATCACATGCGCTCCCACTACACGGCCTCGAATGCTGTGAATGCGGCTCTGGCGGCTGCCAATCGAATGACACCCAAATCGCTGACAATTACGGccacaccagcagcagcagattcAGATGTGGGACTAGGGATAACAGCATCGGTCTCGGCCCCAACAACACCGGCCGCCAATGTGCCGCCGGCAATGGCCAATCAAACGCCCCAGGAGCAGGCCGTATTCCGGCGCAGCCTCGACCAGGCGGCCGATCGTCGCTTCCGGCGGATGCGCTGCCGCATCTGCCAGCGCCGCTTCAGCTCAAAGAAGTCCTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTTGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCGATCAAGGATGAGATGATTATCAAGCAGTTCGAGTGCGAGGTCTGCTCCATTGTCTACAGTTCggagctggagctgcagcagcacaaGCGCAGCGTCCACAAGCTGacctctgcctctgcctccgCCTCGGCCTCCACATCGGCGTCCACTTCCTGCAAGATTGACGATGACTCGCTGATAGACGAGGCCAAGCCTACGGCAGCGGATCTGGCTGATCTCTCGACGCTCGCGGCGGCCAGTGCGTCCACTGCATCGGCCGGGGGTCAGTCCATGCTGGGCACTCCGCTGTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAACGATTATTCCTGCAAGGACTGCGGCAACGTCTACAGCGGACGCAAGAGTCTATGGGTGCATCGATACAAGAAGCATCCGCAAGTACCCGACCCGGCCGAGTGCTCGCTGTGCCGCAAGGTCTTCTTTGACCGGCAGATGCATGACAACCACACGCCCACCTGCAACCGCAAGCCGATCACATCAACGGGTGCCCACCAGCAGcaggatcagcagcagcaggcgtcGCTCCAGCCGGCCAGACGAACCGTTTTCCGGCACAAGACCGGCGATGATGAGGATGATGAGGAGGACGatgatcagcagcagcagctgttgGAGGAGAGGGCCAATAGCGATGGAAACGGGGTGGCTGCATCGGGCAGCACTGTGACCGTGACGGCGGCACCGTCGCTGAAGATCCGCATACCGGAGGTGGCCTGCACCATTTGCGGGGCCCGTTTCACCGATCAGGAGCACTTTAGCAAGCACATACAGAAGCACGAGCAGGAGCTGTACGTGGACAATCCGCTGGCGGCGATGTTCGACGATGGGCCAGCGGATGCCGGGCAGTTCCAGGTGGAGCGGCAGAACGAGAATGGGGAATACGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATCGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACGGCGAAGCGACACAGTTGACCAACAACAATCacacaaccaacaacaacaacaacaacaactcgaTGCTGCACCTCCGCGAGCTGCATGCGGTGGGCCTGATGCccaaccagcagcagcagcaacagcagagcCTCAACAACTcgtgcaacagcagcagcatgaaccacaacaacaacaacaacagcagcagcagcaaccgcagcAAGTCAATGAAGCGGAAGCGTGAGCTGAAATGCGAATACTGCGCCTCCACCTTCATCAGTAACAACAATCTGCGTCGCCACATGTACGAGCTGCACAAGCACGAGGTAAGCAACCTGCCCGAACCGCCGGTGATTGTGGTGGACGATCATCTCACATGCCGTCGCTGCCAGCTGGAGTTCGAGACGAAGGAGCTGTGGATCGAGCACAAGCTGGCCGATGCCAAGGTGGTGCGACCCTTCTGCCCCTTCCAATGGGGCTGTGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTGATGAATCACATCAACAACCATCTCAAGGAGGAGGTCATAGTGCCAGTGGCCACCAAGGCGGCCATTGAGAGGACAGCGGCCATGGAGGcggcgacagcagcagcagatgcaaCCGCAGCGGTGCCATCGATAACATTGGGTGAGGCAGTAGATGAAACGGAGGAGCAATCTGTGGTGAAAGATGagggtgcagcagcagcagcagccgcagcaacaacgacaacagcaGAGAAGTTGGAAGAAGACAGCGATGACCTGGACGAGGATGATAGCTcgggcgaggaggaggagagtTCAGGTACAGGCGATGATgacaacgacgacgaggaTACCGACGACGATGAGGATGGCGAGGGTGaagacgaggacgaggagggaGATGGGGGCGAGGGCGAGGACGAAGAGGGTGTCCAGCCACCGGCTCAGCTGTTGCCACAGAAGCAGCAACACAAAGCGAATCTTAACCAGGACGACGACGATCTCGTCGAGGAGGTCATCAGTTCGGATGACGACGACGTAGAAGATGATGGCGAGGTGGAAagcgacgatgacgacgatgacgaAGAGGACGATGAGGAGGAAGACGTTGAGGAGCCGGAGCCAGTGGGATTGCCGGTGCGACCGCTAATGAATGGCAAGTCGAAAATGCCGCCGCTGATCGTGGCCAGTTCGGAGGATGAGGACGATGGTGTGATGCCCATAGAGGACATCATCGAGGAGGAGTTCGATGAGGATGCCGATCCGGATCCCGATCCGGAGGAGGATGCCATCGAGGAGGTAGACGATGATGATTTAGATGAGGGCGATGCGGAGGACGAGCCGAATGTGGTGTCGACGGCCTCCTCATCGGAGAGCGAGTCCACCACAACGACCACGTCCATATCGCATTCGCATACGCATTCCACGGGAGCTTCTCCAGAGCCACATCAAAAGCCATATCCTCAATGGGCCAAAGCTCTCAGCAGCGGcaacggcggcagcagcagcagaagcaaccGCAAGCAgcgcggcggcagcagcaacaacaacagcattAACGGCAACGGCAGCAAAGACGAAGCCTGA
Protein Sequence: MEILVSCIQLHGGNMAAIKETLVWITPQDRLSLQICHACISYLNSWQSFKNRCFSSQTKQRQWLDANKSKLLTYLDLNSAENGGGGEGGGGGSYDHQQQQQQQQQQQQQSENELDAEKATPTATATAANILDGIHSLKKRKSLTVYVSPKPQQLPQHQLQQLQLQPPARMTATTSSNAQQSLQTLLLQVPASAAAAAASCSSTSTSTTSASHQREQQHQQRQQSHQYRRYHHHHHQQQHQQQHQQQRGKQMLPHHHHQQQQQQQHQHRRQRQFRPQRPVPVANPAPSLRKFKPKLYLPLDIAVPPLPPLPTQPSLPPVATAGSIAAPAAAAELLPGMSGVGVGGGLESLSLSLPLDFSQSCSSSSVGHVHQQQPTAMATTTSTSNPPGNVVSATASVSASATASANASASVSAPTAPLLMPPLPAMPIKDEPIDTDDDYQMKSIDESDDMVDPTMFLERSEHEGDMPLTASDYDYTAQHGVNASSAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPHNTPITKPTPALAAALEIQRAAAAAATAEANRAAGAAGGNISTQKYRQVVMNAFIKCEGGGYDYDNPEQYRSLLTRDKVEFIEQNDEFLEQYQTMTCRCCSKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLFRVLNALRGKTTAAVVLSSAEDVAMDDGATGVVAIPDQDVLAGAGAGVVTMTSPTVTPDVVTPGGGGSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGGGGGGASSDNASTTGSGMARSNSMEHSPGKRSLLGALGIGVGSSADESRSSSAAPPLTSTPKPAGATQVGGGGGGGSTSASASAQSSANRDASAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEEPGSVAKKMRLDDSSNNSSLVGVASQQKECPICNAVFSNNIGLSNHMRSHYTASNAVNAALAAANRMTPKSLTITATPAAADSDVGLGITASVSAPTTPAANVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECEVCSIVYSSELELQQHKRSVHKLTSASASASASTSASTSCKIDDDSLIDEAKPTAADLADLSTLAAASASTASAGGQSMLGTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECSLCRKVFFDRQMHDNHTPTCNRKPITSTGAHQQQDQQQQASLQPARRTVFRHKTGDDEDDEEDDDQQQQLLEERANSDGNGVAASGSTVTVTAAPSLKIRIPEVACTICGARFTDQEHFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDGEATQLTNNNHTTNNNNNNNSMLHLRELHAVGLMPNQQQQQQQSLNNSCNSSSMNHNNNNNSSSSNRSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIVVDDHLTCRRCQLEFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLMNHINNHLKEEVIVPVATKAAIERTAAMEAATAAADATAAVPSITLGEAVDETEEQSVVKDEGAAAAAAAATTTTAEKLEEDSDDLDEDDSSGEEEESSGTGDDDNDDEDTDDDEDGEGEDEDEEGDGGEGEDEEGVQPPAQLLPQKQQHKANLNQDDDDLVEEVISSDDDDVEDDGEVESDDDDDDEEDDEEEDVEEPEPVGLPVRPLMNGKSKMPPLIVASSEDEDDGVMPIEDIIEEEFDEDADPDPDPEEDAIEEVDDDDLDEGDAEDEPNVVSTASSSESESTTTTTSISHSHTHSTGASPEPHQKPYPQWAKALSSGNGGSSSRSNRKQRGGSSNNNSINGNGSKDEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486721;
90% Identity: iTF_00548215;
80% Identity: -