Basic Information

Insect: Drosophila athabasca
Gene Symbol: hang
Assembly: GCA_008121215.1
Location: CM017796.1:17812061-17827228[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.26 17 5.8 1.0 3 23 294 315 293 315 0.93

2 18 0.16 11 6.4 2.7 3 22 423 442 421 442 0.89

3 18 0.00055 0.038 14.2 3.3 1 22 546 567 546 569 0.90

4 18 0.064 4.3 7.7 0.1 2 21 581 600 580 601 0.93

5 18 0.00064 0.044 14.0 0.2 2 23 735 757 734 757 0.95

6 18 0.0018 0.13 12.6 0.1 1 23 765 788 765 788 0.96

7 18 0.00024 0.016 15.4 0.2 2 23 874 895 873 895 0.97

8 18 0.00026 0.018 15.2 2.9 2 23 1005 1027 1004 1027 0.97

9 18 0.021 1.4 9.3 0.2 2 23 1036 1058 1035 1058 0.95

10 18 0.0041 0.28 11.5 0.2 1 23 1071 1094 1071 1094 0.97

11 18 0.00012 0.0079 16.4 1.1 1 23 1167 1189 1167 1189 0.99

12 18 0.0018 0.12 12.6 0.9 1 23 1197 1220 1197 1220 0.96

13 18 0.32 22 5.5 0.5 2 19 1228 1245 1227 1246 0.92

14 18 2.2e-05 0.0015 18.6 1.8 3 23 1330 1350 1329 1350 0.98

15 18 0.00064 0.043 14.0 0.2 1 23 1385 1407 1385 1407 0.97

16 18 5.7e-05 0.0039 17.3 0.6 2 23 1499 1521 1498 1521 0.93

17 18 0.0041 0.28 11.5 0.5 3 23 1577 1597 1577 1597 0.98

18 18 9.4e-05 0.0064 16.6 2.1 1 23 1918 1940 1918 1940 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.26	17	5.8	1.0	3	23	294	315	293	315	0.93
2	18	0.16	11	6.4	2.7	3	22	423	442	421	442	0.89
3	18	0.00055	0.038	14.2	3.3	1	22	546	567	546	569	0.90
4	18	0.064	4.3	7.7	0.1	2	21	581	600	580	601	0.93
5	18	0.00064	0.044	14.0	0.2	2	23	735	757	734	757	0.95
6	18	0.0018	0.13	12.6	0.1	1	23	765	788	765	788	0.96
7	18	0.00024	0.016	15.4	0.2	2	23	874	895	873	895	0.97
8	18	0.00026	0.018	15.2	2.9	2	23	1005	1027	1004	1027	0.97
9	18	0.021	1.4	9.3	0.2	2	23	1036	1058	1035	1058	0.95
10	18	0.0041	0.28	11.5	0.2	1	23	1071	1094	1071	1094	0.97
11	18	0.00012	0.0079	16.4	1.1	1	23	1167	1189	1167	1189	0.99
12	18	0.0018	0.12	12.6	0.9	1	23	1197	1220	1197	1220	0.96
13	18	0.32	22	5.5	0.5	2	19	1228	1245	1227	1246	0.92
14	18	2.2e-05	0.0015	18.6	1.8	3	23	1330	1350	1329	1350	0.98
15	18	0.00064	0.043	14.0	0.2	1	23	1385	1407	1385	1407	0.97
16	18	5.7e-05	0.0039	17.3	0.6	2	23	1499	1521	1498	1521	0.93
17	18	0.0041	0.28	11.5	0.5	3	23	1577	1597	1577	1597	0.98
18	18	9.4e-05	0.0064	16.6	2.1	1	23	1918	1940	1918	1940	0.98

Sequence Information

Coding Sequence: ATGTGCGACACGGCAACAACAGCTACAGCAGTGGCTACAACTGTGGGAGCGTCGTTGGTGTCTGTCACTGGAACGAGCCAGGGAACGGCAGTGGctacagcgacagcagcaggagccacACCGCCAGCTACAACCACAGCGAAACCCGAGCAACAGCGGGCGCGACAAAACTGCTGCCGCCTCTGCATTGCCCCGGCCACGGAATGCATTTCGATCATCAATAGCTATGCGGCCGACAAGGAGCCGCTCTCTACAAAAATCCACAACTGTGTGAACATCAAGATAACACCGCAAGATCGGCTGTCACTTCAGATCTGCCACGCCTGCATCAGTTACCTTAACTCGTGGCAGAGTTTCAAGAATCGCTCGGTTAGCGCACAAAGCAAACAGCGCCAGTGGCTGGAGGCCAACAAGAGTAAGCTACTCAGCTATTTGGATTTGAACTGTGCCGGCGagaatggaggaggaggaggtcaCCACCAGAACCAGtcacaccagcagcagcagcagccgcagcaccATCATTCGGAGAATGAGATTGATTTGGAGAAGCCATCGGCCGCCCAAATATTGGACGGCATACCGTCGCTGAAGAAACGCAAATCTTTAACAGTCTATCCACTGCCCGCTATTCCCATCAAGGATGAGCCCATTGACACAGATGATGACTATCAAATGAAATCGCTGGACGAATCCGACGACATGGTCGATCCCACAATGTTCCTAGAACGCTCCGAGCACGAGGGCGATATACCATTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTAAACGCAGAGACAGCGGCCGCCTCTCTGCCGCCAAATGCCGTGGCAAATGTGGCCGCTGCCGGGGACTCAAAGGTGGCCAGCTGCAGGGCATGCAGCCTTCAGTTTTCGACACGTGCCAATGCCCGTCGCCATGAGCGAAATTTGCACCCAAATCTGTTCCAACTGTCGACGGACTCGCCCAACAATACGCCAATCACAAAGCCCACACCGGCACTGGCGGCTGCATTGGAGATTCAGCGTGCCGCCGCCGAGGCGGCCACCGAGGAGGCCAGCAAAGCTGCGGGCGCTGCCGGGGGTAATATATCGACCCAAAAGTATCGTCAGGTGGTGATGAACGCCTTCATCAAGTGCGAGGGTGGGGGCTTTAACTATGATAATCCCGAGCAATACCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATCGAGCAGAATTACGAATTCCTGGAGCAGTACCAGACGATGACATGCCGCTGCTGCGACAAATACTTTAGTACGTACAAGAACTTTATGGCGCATGTGCGTAAAAAGTATCCGCTGTTGCCGCGCAATCTCTGCTTCAACTGCCTCAAGATGAACGAATCGAAGGCTCTGTTCATTTCGCATCTCAAGAAGCGCAACTGCATCAATCTGTTTCGTGTGCTGAACGCCCTGCGCGGCAAGCAGCCAAATTTCCATCCCTCATCGGACATTGGATCATCATCGTTTGGTGGAGAGACCACCATCACCCCCACCATCACCAGTCCCAATGTCGTTGTACCGCTGCTGTTAGATAACAGCTCAAGCGGCGAACGGCCAGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTTTACGAGTGTAAACTCTGCCCAAAGGGCTTCCGCACCAAGCACGAGTTTCGCACCCATGTGTACGACAAGCATGCGGACGTGCAGCGCAAGGACAACAATTCGATTCAGTGCAGCTTCTGTGGTCTGGACTTTGCCGATCCAGTGGACAGGCGCCGCCACTACAACAATATGGACTGCATTGTTCGCCTCCGGTGCATGACATGTGATGCCAAGGTGGAGACACATCAGCGTTTCCTCGATCATGTCTATCAGGATCATCTTGGGGGCATAAGCAGCGAGAATGCCTCTACTGTGAGTGGAATGGGCGGCGCCGGCGGtggcaggagcaacagcagtatTGAGAACTCGCCTGGGAAGCGGAGTCTACTAGGTGCTCTCGGGATTGGGGTTGGCTCCCCCGCCGATGAGTCACGAAGTGGCGGCagtgcagcggcagctgcagcaccCAATCAAACCTCTACGCCAAAGCCAACATCGGGTGGTGGAGCGGCGGGCACGACATCTGGCTCTCTAAATCGTGATGCTGGTGGTGCGCCGAAATCGCAGTATTTCTCACGAATGCCACAGGTTTGCCCCATCTGTGGCCAACAGTACAACAACTACAATAACGTGCTGCGTCACATGGAATCGAAGCATCCGAACAAACTCCCGGAGACATACAAGTGTGTGCGATGCGGCCTGGGATATCCGAGGATCTCGTATCTCCGAGAGCATATGATCAACGTTCATGGCGTGGACAAGAATCGTCATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCCGTGAAGCTGGCCGACGGCAGTACACCGAATGTATCCACGGGTCGTTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAGACCGGCAGCGTGGCCAAGAAGATACGTCTGGACGatagcagcaacaacagcagtctGGTGGGCGGCGTGGCCAGCCAGCAAAAAGAATGCCCCATCTGCAACGCACTGTTCAGCAACAATATCGGCTTGTCAAATCACATGCGCTCGCATTACACGGCCTCGAGTACCGTGAATGCTGCTCTGGTGGCGGCCAATCGTATGACACCCAAATCCTTGACCATAACCGCCACCCCAGCCACAGAGACGGTCACATCATCGACCCCGGTGGATGTCGACGATGATGAGGGCATTATAACGCTCGAAACGGGAAATATTATGGCCAGCATCAGTGGTGGTAGAGGTgtcgcttctgctgctgctgctgctggtactgGTGCTGTTGCCGTCCCTCCTGCCATGGTTAATCAGACGCCCCAAGAGCAGGCAGTCTTTCGTCGTAGTCTGGATCAGGCGGCGGATCGTCGGTTCCGCCGGATGCGTTGCCGCATCTGTCAGCGGCGTTTTAGCTCAAAGAAATCATACCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTTATCAAATGCAAGCTGTGCAATGCAGAGTTTGCCTACGAGAAGGGTCTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGATGAGATGATTGTGAAGCAGTTTGAGTGCGATGTCTGTTCGATTGTGTACAGCTCAGAGCTGGAACTGAAGCAGCACAAGAAGAGTGTCCACAAGCTGGCATCCGTGTCGGTGTCTGCATCCGCCTCGGCATCGgcttctgcctctgcatcCACATCCTCGAAAATCGATGATGATTCACTGATGATAGAGGATATCGGTGGCAATAGAAGCAGTCATCAGCATCACAGCAAGGCATCTGGTGATCTGGCCGATCAGTCCAACATCtctgctgccaccgccactgccacaacGACGCCGTTGTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTTAACACAAACAAGAAGCTGGCCATCCACATTAACTCGCACGATGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTATAGCGGTCGCAAGAGTCTATGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCCGACCCTATCGAGTGCACGCTGTGCCGCAAGGTATTCTTTGACCATCAGATGCTGGACAACCATACGCCAACCTGCAACCGAAAGCCGATTACCGCCACGGGGGCGCATCAGCAGGAGCTGCAGACAAATCCGGCGCTGGGTCGGCCCGTATTCAGGCACAAGACTGGCGACGATGATGACGAGGAagagcaacatcagcagcagcttaATCCACAGGAGGATGCTGGCGATGGAGGAGCAGTAGCGGTAGCCACATCGAGTGGTGGCACCATTAGTGCGGGCAGTAACAAAAAGTTGCGCTTACTGGATGTGGCCTGTACAATTTGTGGTGCCCGATTCACCGATCAGGAGCACTTTACCAAGCACTTACAGAAGCATGAGCAGGATCTGTATGTGGATAATCCGCTGGCAGCGATGTTCGACGATGGGCCAGCGGATGTGGCCCAATTTAAGGTGGAGGGCCAGAACGAGAATGGGGAATATGCGTGCGATATGTGTACGAAGACATTCCCCCAAGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGAatatcaacaacaacaacaattcgGTGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGATGCCCAACcaacaacagaagcaacagcagagcCAACAGCAGAGCCAACAGCAGAGCAACTCCACGTCCACgccgaacaacaacaacagcagcagcaacaacaacaacagcagcagcagcagcaagagcaaaTCAATGAAGCGTAAACGTGAATTAAAATGCGAATACTGCCCCTCGACATtcatcagcaacaacaacctgCGACGACACATGTATGAACTGCATAAGCACGAGGTGAGTAGCCTGCCAGCACCACCCGTGATTGTGGTAGATGACCCGCTAAGCTGCCGACGTTGTGGCGATATCAAATTCGCGACGAAAGAACTGTGGATCGAGCACAAGCTGGCCGATGCGAAGGTGGTGCGACCATTTTGTCCCTTCCAATGGGGCTGTGACATGTGTGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATGAATCACATCAATAATCATTTGAAGGAGGATGTTATTGTGCCAGTGTCCACACAAGCGGCCATCGATAGAGAACAACGAGCATCGAcagaatcatcatcatcagcctCCGAGGCAACAACATCCAAAGCGAAGGCGTCATCCGCCTTGCCGGCTTCAACCAGCGCAGCATTGCAGAAAAAAACTGAGGAAAATGGTGGACTGGAGACAGCAGAGGCGGCGGTAAAGGCAGAGGAGGATGATAGCGAAATGGAGGATGGCGACAGTTCAGACGCTGATGAAGAAAGCTCTGGCACAGgggatgacgacgacgatgacggcgacgacgacgacgacgatgatgatgaagatgaagacgaTGACGAAGATGAgggcgaggacgaggaggGTGTGCCCCCACCAACACCTGCCACACAActgttgcaacagcaacacaaatCCAATATTGACAAGGATGAAGATCTCGTCGAAGAAGTGATGAGCTCTGATGAGGAGGCGGAGGAAGGCGAAAGCCAAAGCGATGAGGACGATGACGAAGATGACGATGAagacgacgatgacgaggaggaagaggaacaGGGACAGGAACAGGGTTCACAGCCCCTGATGAATGGCAAGTCGAAAGAGCATCAACAGCAAATCGAAGAGATATTGCCCAGctccgacgacgacgaagaggAGCAGGATGGCAATTTAGATGGCCATTTGATGGCCATTGAAGACATTATTGAAGAAGAATATGATGAAGACGATGATGTGGAGGAGGTAGACGATGGTGCAGTCCATCCAGATCCCGACGATGTTATCGAAGAGGTCGACGACGATGATGCGGATGAAGTGGATGATGAGCAGAATGTCGATGGGGGGGCCACATCGTCGGCCTCATCGTCAGAGAGCGAATCAACATCCACGACCACATCCAATTCGCATTCAACTGGTGAGCGGCGAAAGAAGGCTGGCGACCAGTCGTCAAAACCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTTCTCCAGTCTCACATCAAAAGCCATTTCCTCAATGGTCCAAAAATCTCTACCTCACAAGCAGCAAGCAacgcaacagcaacggcaacgccgacggcgacagcgacggcgacgactGTGTCCAGCAATTGTAACAACAATGCGTCGACCAAATCCACGAAGCTCTCtccagcagctggagcagcCAACCACAACCGTCAAAGAAGTGCCGTCGTCGCCGCAGAAATGGGGGCCAGCggtagcagcagcggcagcagcaattgA
Protein Sequence: MCDTATTATAVATTVGASLVSVTGTSQGTAVATATAAGATPPATTTAKPEQQRARQNCCRLCIAPATECISIINSYAADKEPLSTKIHNCVNIKITPQDRLSLQICHACISYLNSWQSFKNRSVSAQSKQRQWLEANKSKLLSYLDLNCAGENGGGGGHHQNQSHQQQQQPQHHHSENEIDLEKPSAAQILDGIPSLKKRKSLTVYPLPAIPIKDEPIDTDDDYQMKSLDESDDMVDPTMFLERSEHEGDIPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDNPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLFRVLNALRGKQPNFHPSSDIGSSSFGGETTITPTITSPNVVVPLLLDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSENASTVSGMGGAGGGRSNSSIENSPGKRSLLGALGIGVGSPADESRSGGSAAAAAAPNQTSTPKPTSGGGAAGTTSGSLNRDAGGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNGGTLDDDEEETGSVAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASSTVNAALVAANRMTPKSLTITATPATETVTSSTPVDVDDDEGIITLETGNIMASISGGRGVASAAAAAGTGAVAVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKKSVHKLASVSVSASASASASASASTSSKIDDDSLMIEDIGGNRSSHQHHSKASGDLADQSNISAATATATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECTLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELQTNPALGRPVFRHKTGDDDDEEEQHQQQLNPQEDAGDGGAVAVATSSGGTISAGSNKKLRLLDVACTICGARFTDQEHFTKHLQKHEQDLYVDNPLAAMFDDGPADVAQFKVEGQNENGEYACDMCTKTFPQVIALKVHRKWHFRGDSKQNHIDSETTNINNNNNSVNNSTSMLRELHAVGLMPNQQQKQQQSQQQSQQQSNSTSTPNNNNSSSNNNNSSSSSKSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDDPLSCRRCGDIKFATKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVSTQAAIDREQRASTESSSSASEATTSKAKASSALPASTSAALQKKTEENGGLETAEAAVKAEEDDSEMEDGDSSDADEESSGTGDDDDDDGDDDDDDDDEDEDDDEDEGEDEEGVPPPTPATQLLQQQHKSNIDKDEDLVEEVMSSDEEAEEGESQSDEDDDEDDDEDDDDEEEEEQGQEQGSQPLMNGKSKEHQQQIEEILPSSDDDEEEQDGNLDGHLMAIEDIIEEEYDEDDDVEEVDDGAVHPDPDDVIEEVDDDDADEVDDEQNVDGGATSSASSSESESTSTTTSNSHSTGERRKKAGDQSSKPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKISTSQAASNATATATPTATATATTVSSNCNNNASTKSTKLSPAAGAANHNRQRSAVVAAEMGASGSSSGSSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00574991; iTF_00601200; iTF_00484570; iTF_00564091; iTF_00515036;
90% Identity: -
80% Identity: -