Basic Information

Insect: Drosophila guanche
Gene Symbol: hang
Assembly: GCA_900245975.1
Location: NW:61666-80775[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.26 15 5.8 1.0 3 23 298 319 297 319 0.93

2 18 0.59 35 4.7 2.7 3 22 427 446 425 446 0.89

3 18 0.00056 0.033 14.2 3.3 1 22 548 569 548 571 0.90

4 18 0.064 3.8 7.7 0.1 2 21 583 602 582 603 0.93

5 18 0.00065 0.038 14.0 0.2 2 23 740 762 739 762 0.95

6 18 0.0019 0.11 12.6 0.1 1 23 770 793 770 793 0.96

7 18 0.00024 0.014 15.4 0.2 2 23 879 900 878 900 0.97

8 18 0.00027 0.016 15.2 2.9 2 23 1011 1033 1010 1033 0.97

9 18 0.021 1.2 9.3 0.2 2 23 1042 1064 1041 1064 0.95

10 18 0.0041 0.24 11.5 0.2 1 23 1077 1100 1077 1100 0.97

11 18 0.00012 0.0069 16.3 1.1 1 23 1180 1202 1180 1202 0.99

12 18 0.0018 0.11 12.6 0.9 1 23 1210 1233 1210 1233 0.96

13 18 0.32 19 5.5 0.5 2 19 1241 1258 1240 1259 0.92

14 18 3e-05 0.0018 18.2 1.4 3 23 1346 1366 1345 1366 0.98

15 18 0.00099 0.058 13.4 0.5 1 23 1401 1423 1401 1423 0.97

16 18 5.7e-05 0.0034 17.3 0.6 2 23 1513 1535 1512 1535 0.93

17 18 0.0041 0.24 11.5 0.5 3 23 1591 1611 1591 1611 0.98

18 18 9.5e-05 0.0056 16.6 2.1 1 23 1955 1977 1955 1977 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.26	15	5.8	1.0	3	23	298	319	297	319	0.93
2	18	0.59	35	4.7	2.7	3	22	427	446	425	446	0.89
3	18	0.00056	0.033	14.2	3.3	1	22	548	569	548	571	0.90
4	18	0.064	3.8	7.7	0.1	2	21	583	602	582	603	0.93
5	18	0.00065	0.038	14.0	0.2	2	23	740	762	739	762	0.95
6	18	0.0019	0.11	12.6	0.1	1	23	770	793	770	793	0.96
7	18	0.00024	0.014	15.4	0.2	2	23	879	900	878	900	0.97
8	18	0.00027	0.016	15.2	2.9	2	23	1011	1033	1010	1033	0.97
9	18	0.021	1.2	9.3	0.2	2	23	1042	1064	1041	1064	0.95
10	18	0.0041	0.24	11.5	0.2	1	23	1077	1100	1077	1100	0.97
11	18	0.00012	0.0069	16.3	1.1	1	23	1180	1202	1180	1202	0.99
12	18	0.0018	0.11	12.6	0.9	1	23	1210	1233	1210	1233	0.96
13	18	0.32	19	5.5	0.5	2	19	1241	1258	1240	1259	0.92
14	18	3e-05	0.0018	18.2	1.4	3	23	1346	1366	1345	1366	0.98
15	18	0.00099	0.058	13.4	0.5	1	23	1401	1423	1401	1423	0.97
16	18	5.7e-05	0.0034	17.3	0.6	2	23	1513	1535	1512	1535	0.93
17	18	0.0041	0.24	11.5	0.5	3	23	1591	1611	1591	1611	0.98
18	18	9.5e-05	0.0056	16.6	2.1	1	23	1955	1977	1955	1977	0.98

Sequence Information

Coding Sequence: ATGTGCGACacggcggcaacaacaactacaacagtTGTGGCAACTACAACGGTGGCTGCAGCGTCGTCGGTGTCTGGCCCTGGAACAAGCCAGAGTCAGGGAACGGCAGCGGCTACATCAGCGACTGCAGGAGCCACACCGCCAGCTACAACCACAGCGAAAcccgagcagcaacagcgggcGCGACAAAACTGCTGCCGCCTCTGCATTGCCCCGGCCTCGGAATGCATTTCGATCATCAATAGCTATGCGGCCGACAAGGAGCCGCTCTCTACAAAAATCCACAACTGTGTGAACATCAAGATAACACCTCAAGATCGGCTGTCACTGCAGATCTGTCACGCCTGCATCAGCTACTTAAACTCGTGGCAGAGCTTTAAGAATCGCTCGGTGAGCGCACAGACCAAACAGCGTCAGTGGCTGGAGGCCAACAAGAGCAAGCTGCTCAGCTATTTGGATTTGAACAGTGCCGAGAATGGAGGAGGtcatcagcagcaccaacagaaccagtcacagcagcagcatcagcagcatcattcGGAGAATGACATCGATTTGGAGAAGCCATCGGCAGCTCAAATATTGGACGGCATACCATCGCTGAAGAAACGAAAATCCCTAACAGTCTATCCACTGCCCGCTATACCCATCAAGGATGAGCCCATTGACACCGATGATGACTATCAAATGAAATCGTTGGACGAATCCGAAGACATGGTCGATCCCACAATGTTCCTAGAACGCTCCGAGCACGAGGGCGATATACCACTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTGAATGCAGAGACAGCGGCCGCCTCGTTGCCGCCTAATGCTGTGGCTAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGTAGTCTTCAGTTTTCGACACGTGCCAATGCCCGTCGCCATGAGCGGAATTTGCACCCAAATCTGTTCCAATTGTCGACAGACTCGCCCAACAATACGCCCATCACAAAGCCCACCCCGGCACTGGCGGCAGCACTGGAGATACAGCGTGCCGCCGCCGAGGCGGCCACCGAGGAGGCCAGCAAGGCTGCCGGCGCTGCCGGTGGCAATATATCGACCCAAAAATATCGCCAGGTGGTTATGAATGCCTTCATCAAGTGCGAGGGCGGTGGCTTCAACTACGACAGTCCCGAGCAATATCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATCGAGCAGAATTACGAATTCCTCGAGCAGTACCAGACGATgacatgccgctgctgcgaaAAATACTTTACTACGTACAAGAACTTTATGGCGCATGTGCGTAAGAAGTATCCGCTGTTGCCGCGTAATCTCTGCTTCAACTGCCTCAAGATGAACGAATCGAAGGCGCTCTTCATATCGCATCTCAAGAAGCGCAACTGCATCAATCTGTATCGTGTGCTGAACGCACTGCGCGGCAAGCAGCCCAATTTCCATCCCTCAACGTCTGACATGGGATCGTTTGGTGGCGAGACGAGCAACGCAGCGATTACCAGTCCCACTGTCGTGGTGCCACTGCTGATGGATAACAGCTCGAGCGGCGAGAGGCCAGAGAAGCTGCGcgccaaggagctgctggtgaATAAGCTTTACGAGTGCAAGCTCTGCCCGAAGGGTTTCCGCACCAAGCACGAGTTCCGCACTCATGTGTACGACAAGCATGCGGACGTGCAGCGCAAGGACAACAATTCGATTCAGTGCAGCTTCTGTGGCCTGGACTTTGCAGATCCCGTGGACAGGCGACGGCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACGTGCGATGCGAAAGTGGAGACGCATCAGCGTTTCCTCGATCATGTCTATCAGGATCATTTGGGTGGCATCAGCAGCGACAATGCCTCCACGGCGAGCGGATTggtcggcagcagcagcagcattgaaaACTCACCTGGCAAGCGGAGTCTATTGGGTGCCCTTGGTATTGGTGTTTGCTCTCCCGCCGATGAGTCACGCAGCGGCAgtgcagcagcgggagcaggagGATCAGCAGGGGCAGCACCCAATCAAACCTCAACGCCAAAGCCAACATCGGGAGGTGGTGGAGTCGCGTGCACAACAcctggcggcagcggcggctccCTAAATCGTGACAGCGCTCCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTATGCCCCATCTGTGGGCAGCagtacaacaactacaacaacgtGCTGCGGCACATGGAATCGAAGCATCCAAACAAACTGCCCGAAACATACAAATGCGTACGCTGCGGCCTGGGCTATCCACGAATCTCGTATCTCCGCGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGTCATTCCGGTGGCTTTGAGTATATTGTGAATGCGGATGCCGTCAAGCTGGCCGATGGCAGTACACCGAACGTGTCCACGGGTCGCTACGACTACGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCGatgacgacgaggaggagactgGCAGCGTGGCCAAGAAGATACGCCTGGATGATAGCAGCAATAACAGCAGCCTGGTGGGTGGCGTGGCCAGCCAGCAAAAGGAATGCCCCATCTGCAATGCGCTTTTTAGCAACAATATTGGCCTGTCCAATCACATGCGCTCCCACTACACGGCCTCGAATTCGGTGAATGCCGCCCTGGTGGCTGCCAATCGCATGACACCCAAGTCGCTGACGATAACCGCCACACCAGCCACAGAGACGGTCACCTCAGCGACAGCCTCACTCGATGTGGAGGATGATGAGGCTCTTATAGCGCTTGAAAAGGCAAAGATAATGGCCAGCGTGAACGCTGCCAGAGCGGCTAGAGTTGCTAGTGCTGCTTCTGGGGCTTCTGCATCTTCTGTGCCGCCTGCCATGGCCAATCAGACGCCCCAGGAGCAGGCTGTCTTTCGTCGCAGCTTGGATCAGGCGGCGGATCGTCGCTTCCGACGCATGCGCTGCCGCATTTGTCAGCGGCGTTTTAGCTCCAAGAAATCGTATCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAATGCAAGCTGTGCAATGCAGAGTTCGCCTACGAAAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCATGGCCGTGCGATCAAGGACGAGATGATTGTGAAGCAGTTCGAGTGCGATGTCTGCTCGATTGTGTACAGctcggagctggagctgaagcagcaCAAGAAGAGTGTCCATAAGTTCACATCATCCGTGTCGGTGTCGGCATCCGCCTCGGCatcggcctctgtctctgcctctgcgtcaACATCCTCGAAAATGGATGACGATTCAATGATGCTGGAGGATATGGGTGGCAATAGAAGCCGCCACCATCAACAtcagcaccacagcagcaagGCGTCTGCCGATTCGGTCGATCAGTCCATAATTTCTGGtgcggctgccacagccacaacgacGCCGCTGTATTGGTACCAATGCAAATACTGTCCCTCTAACTTTAACACAAACAAGAAGCTGGCCATCCACATTAACTCGCACGACGAGTTCGATTCGAATGATTATTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGTCTTTGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCCGATCCCATTGAGTGCACGCTGTGCCGCAAGGTGTTCTTCGATCATCAGATGCTGGACAATCATACGCCAACCTGCAACCGCAAGCCGATTACCGCCACTGGGGCGcatcagcaggagctgctgacGCAGGCAAATCAATCGCAGGGTCGTGCCGTATTCCGACACAAGACTggggacgatgatgatgaggaagacatgcagcagcatcaccaacagcaacaggatgCAGGCGATGCAGTGGCAACAGtgacagcagcaactgctgcagcggcagccacatcGAGTGGTGGCAGTAGCAAAAAGATGCGCATACCGGAGGTGGCATGCACCATTTGTGGTGCACGCTTCACCGATCAGGAGCACTTTAGCAAGCACATACAGAAGCATGAGCAGGATCTGTATGTGGATAACCCATTGGCGGCAATGTTCGATGATGGGCCAGCGGATGCGGCACAGTTAAAGATCGAGGGCCAGAACGAGAACGGGGAATATGCGTGCGATATGTGCACGAAGACATTCCCCCAGGTGATTGCACTCAAAGTGCATCACAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGaatatcaacaacaacaacaacaattcggTGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGACGCccaatcaacagcagcagcagcagcatcagagcCAACAGCAGAATTCCACGTCCACgccgaacaacaacaacaggagcagcagcaacaacaacaacaacagcagcagcaccaagaGCAAATCGATGAAACGTAAACGTGAATTGAAATGCGAATACTGCCCATCGACCTTCATCAGTAACAACAACCTGCGACGACATATGTATGAGCTGCACAAGCATGAGGTGAGTAGCCTGCCAGCACCGCCAGTGATTGTGGTAGATGAGCCGCTCAGCTGCCGACGCTGTGGCGACATTCAATTCGAGACAAAAGAACTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTTCGACCCTTTTGTCCCTTCCAATGGGGCTGTGACATGTGCGGCGAGTACTTGTCGCGCAAAGAGAAGCTCATGAATCACATCAATAATCATTTGAAGGAGGATGTCATTGTGCCAGTGGCCACACAAGCGGCCATTGACAGAGAACGTGCAGCATCCTCATCAGAGGCAACAACATCCAAAGCAACATCAGCATCCGTGTTGGTTGAGCAGAAGCCAACCGGCACAGCGTTGCAAAAGAAAACGGAAGAGAATGGTGGACTGGATGCAGCGGTGGCGACAGCGGCAGAGTCGGTGAAGGCAGGCGAAGATGATAGCGAAATGGAGGATGTCGACAGTTCAGACGCTGATGAAGAAAGCTCTGGCACAGGGGATGAGgaagacgacgatgatgatgatggcggaGAGGACGATgaagatgacgatgatgaagaAGATGAGCTgcaggacgacgacgacgatgatgatgaagaagaAGAGGGTGAGGGTGAAGATGAAGAAGGGGTCCCCCCACCAACACCTGCCGCACAATTGTTGCAACacaaacagccacaacaacaacaacaacaacacaaagcCAATAACAATAGTATTGACAATGTTGATGATCTCGTTGAGGAAGTGAACAGCTCTGATGATGAGGAAGCCGATGTCGAAGTAGGGAGCGAAAGTCAAACCCAAAGCGATgaagacgatgacgatgaagaAGATGATGAAGCTGACATTagtgaggaggaggagggtgaGGAGCTGGGCTCGGCACAGCCCCTGACTAATGGCAAGTCGAATGAGCATAATGCGACGCCCCAACAGCAAATGGAGCAAATTTTGCCCAGCTCTGACGAGGAAggcgagaacgagaacgacaacgacaacgacaacgtaGAGGAAGATGGTGGCAATGCAGATGGTCATACATTGGCCATTGAGGACATTATTGAAGAAGAATATGATGAAGACGATGATATGGAGGAGGTATACGATGATCAGAATGCTGATGGTGGTGCCACATCGTCGGTATCATCCTCAGAGAGCGAATCAACATCCTCGACCACATCCAATTCGCATTCAACTGGTGAGCGGCGTAAGAAGGCTGGCGGCGATGAGTCGTCAAATCCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTTCTGCAGTCTCACATCAAAAGTCATTTTCGCAATGCCCCAAAAATCTCAGCCAAATCAACCGCAACGGCCACGGTAACGACGGTGGCATCGGCGACGACTGTTCCCAGTAGTTGTAACAACAATGCCTCGACCAAATCCTCCTTAAAGCACTCTCCCGCAGCGgccagcggtggcagcagtaGCAATTGA
Protein Sequence: MCDTAATTTTTVVATTTVAAASSVSGPGTSQSQGTAAATSATAGATPPATTTAKPEQQQRARQNCCRLCIAPASECISIINSYAADKEPLSTKIHNCVNIKITPQDRLSLQICHACISYLNSWQSFKNRSVSAQTKQRQWLEANKSKLLSYLDLNSAENGGGHQQHQQNQSQQQHQQHHSENDIDLEKPSAAQILDGIPSLKKRKSLTVYPLPAIPIKDEPIDTDDDYQMKSLDESEDMVDPTMFLERSEHEGDIPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDSPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCEKYFTTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLYRVLNALRGKQPNFHPSTSDMGSFGGETSNAAITSPTVVVPLLMDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSDNASTASGLVGSSSSIENSPGKRSLLGALGIGVCSPADESRSGSAAAGAGGSAGAAPNQTSTPKPTSGGGGVACTTPGGSGGSLNRDSAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNGGTLDDDEEETGSVAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASNSVNAALVAANRMTPKSLTITATPATETVTSATASLDVEDDEALIALEKAKIMASVNAARAARVASAASGASASSVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKKSVHKFTSSVSVSASASASASVSASASTSSKMDDDSMMLEDMGGNRSRHHQHQHHSSKASADSVDQSIISGAAATATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECTLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELLTQANQSQGRAVFRHKTGDDDDEEDMQQHHQQQQDAGDAVATVTAATAAAAATSSGGSSKKMRIPEVACTICGARFTDQEHFSKHIQKHEQDLYVDNPLAAMFDDGPADAAQLKIEGQNENGEYACDMCTKTFPQVIALKVHHKWHFRGDSKQNHIDSETTNINNNNNNSVNNSTSMLRELHAVGLTPNQQQQQQHQSQQQNSTSTPNNNNRSSSNNNNNSSSTKSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDEPLSCRRCGDIQFETKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVATQAAIDRERAASSSEATTSKATSASVLVEQKPTGTALQKKTEENGGLDAAVATAAESVKAGEDDSEMEDVDSSDADEESSGTGDEEDDDDDDGGEDDEDDDDEEDELQDDDDDDDEEEEGEGEDEEGVPPPTPAAQLLQHKQPQQQQQQHKANNNSIDNVDDLVEEVNSSDDEEADVEVGSESQTQSDEDDDDEEDDEADISEEEEGEELGSAQPLTNGKSNEHNATPQQQMEQILPSSDEEGENENDNDNDNVEEDGGNADGHTLAIEDIIEEEYDEDDDMEEVYDDQNADGGATSSVSSSESESTSSTTSNSHSTGERRKKAGGDESSNPSFTCDLCQLCFDSQELLQSHIKSHFRNAPKISAKSTATATVTTVASATTVPSSCNNNASTKSSLKHSPAAASGGSSSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480993;
90% Identity: iTF_00601200;
80% Identity: -