Basic Information

Insect: Drosophila persimilis
Gene Symbol: hang
Assembly: GCA_003286085.2
Location: NW:1827413-1847152[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.29 17 5.8 1.0 3 23 290 311 289 311 0.93

2 18 0.19 10 6.4 2.7 3 22 419 438 417 438 0.89

3 18 0.00063 0.036 14.2 3.3 1 22 542 563 542 565 0.90

4 18 0.073 4.1 7.7 0.1 2 21 577 596 576 597 0.93

5 18 0.00073 0.041 14.0 0.2 2 23 734 756 733 756 0.95

6 18 0.0021 0.12 12.6 0.1 1 23 764 787 764 787 0.96

7 18 0.00027 0.015 15.4 0.2 2 23 869 890 868 890 0.97

8 18 0.0003 0.017 15.2 2.9 2 23 995 1017 994 1017 0.97

9 18 0.024 1.3 9.3 0.2 2 23 1026 1048 1025 1048 0.95

10 18 0.0065 0.36 11.0 0.2 1 23 1061 1084 1061 1084 0.97

11 18 0.00013 0.0074 16.4 1.1 1 23 1165 1187 1165 1187 0.99

12 18 0.002 0.12 12.6 0.9 1 23 1195 1218 1195 1218 0.96

13 18 1.5 85 3.6 0.4 2 19 1226 1243 1225 1244 0.92

14 18 3.4e-05 0.0019 18.2 1.4 3 23 1339 1359 1338 1359 0.98

15 18 0.0093 0.52 10.5 0.1 1 23 1394 1416 1394 1416 0.97

16 18 6.5e-05 0.0037 17.3 0.6 2 23 1498 1520 1497 1520 0.93

17 18 0.0047 0.26 11.5 0.5 3 23 1576 1596 1576 1596 0.98

18 18 0.00011 0.006 16.6 2.1 1 23 1934 1956 1934 1956 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.29	17	5.8	1.0	3	23	290	311	289	311	0.93
2	18	0.19	10	6.4	2.7	3	22	419	438	417	438	0.89
3	18	0.00063	0.036	14.2	3.3	1	22	542	563	542	565	0.90
4	18	0.073	4.1	7.7	0.1	2	21	577	596	576	597	0.93
5	18	0.00073	0.041	14.0	0.2	2	23	734	756	733	756	0.95
6	18	0.0021	0.12	12.6	0.1	1	23	764	787	764	787	0.96
7	18	0.00027	0.015	15.4	0.2	2	23	869	890	868	890	0.97
8	18	0.0003	0.017	15.2	2.9	2	23	995	1017	994	1017	0.97
9	18	0.024	1.3	9.3	0.2	2	23	1026	1048	1025	1048	0.95
10	18	0.0065	0.36	11.0	0.2	1	23	1061	1084	1061	1084	0.97
11	18	0.00013	0.0074	16.4	1.1	1	23	1165	1187	1165	1187	0.99
12	18	0.002	0.12	12.6	0.9	1	23	1195	1218	1195	1218	0.96
13	18	1.5	85	3.6	0.4	2	19	1226	1243	1225	1244	0.92
14	18	3.4e-05	0.0019	18.2	1.4	3	23	1339	1359	1338	1359	0.98
15	18	0.0093	0.52	10.5	0.1	1	23	1394	1416	1394	1416	0.97
16	18	6.5e-05	0.0037	17.3	0.6	2	23	1498	1520	1497	1520	0.93
17	18	0.0047	0.26	11.5	0.5	3	23	1576	1596	1576	1596	0.98
18	18	0.00011	0.006	16.6	2.1	1	23	1934	1956	1934	1956	0.98

Sequence Information

Coding Sequence: ATGTGCGACACGGCGGCAACAACAGCTACACCAGTGGTGGCAGCTACAACTGTGGGAGCGGCTTCGGTGTCTGGCACTGGAACCAGCCAGGGAACGGCAGCGGCTACACCAGCGACAGCAGGAGCCACACCGCCAGCTACAACCGCATCGAAACCCGAGCAACAGCGGGCGCGACAAAACTGCTGTCGCCTCTGCATTGCCCCGGCCACGGAATGCATTTCGATCATCAATAGCTATGCGGCCGACAAGGAGCCGCTATCGACAAAAATCCACAACTGTGTGGACATCAAGATAACACCACAAGATCGGCTGTCACTTCAGATCTGCCACGCCTGCATCAGTTACCTAAACTCGTGGCAGAGCTTCAAGAATCGGTCGGTTAGCGCACAGAACAAACAGCGGCAGTGGCTGGAGGCCAACAAGAGTAAGCTCCTCAGCTATTTGGATTTGAACAGTGCCGAGAATGGAGGAGGTCATCAGCAGCATCACCAtcagaaccagcagcagcatcattcGGAGAATGAGATCGATTTGGAGAAGCCATCGGCCGCCCAAATATTGGACGGCATACCCTCGCTGAAGAAACGCAAATCCCTAACAGTCTATCCACTGCCCGCAATTCCCATCAAGGATGAGCCCATTGACACAGATGATGACTATCAAATGAAATCGCTGGACGAATCCGATGACATGGTCGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTACCATTAATGACCTCCGACTATGATTATACGGCGCAGCATGGTGTGAACGCAGAGACGGCGGCCGCCTCGCTGCCACCAAATGCTGTGGCTAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGCAGCCTCCAGTTTTCGACACGTGCCAATGCCAGGCGCCATGAGCGAAATTTGCACCCAAATCTGTTCCAATTGTCGACGGACTCGCCCAACAATACGCCCATCACAAAGCCCACCCCGGCACTGGCGGCTGCATTGGAGATTCAGCGTGCCGCCGCCGAAGCGGCCACCGAGGAGGCCAGCAAAGCTGCAGGCGCTGCCGGGGGTAATATATCGACCCAAAAATACCGTCAGGTGGTGATGAACGCCTTCATCAAGTGCGAGGGTGGGGGCTTCAACTATGACAGTCCCGAGCAGTACCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATCGAGCAGAATTACGAATTCCTGGAGCAGTACCAGACGATGACATGTCGCTGCTGCGACAAATACTTCAGTACGTACAAGAACTTTATGGCGCATGTGCGTAAAAAGTATCCGCTGTTGCCGCGCAATCTCTGCTTCAACTGCCTCAAGATGAACGAATCGAAGGCTCTGTTCATTTCCCATCTCAAGAAGCGCAACTGCATCAATCTATTTCGTGTGCTGAACGCCCTGCGCGGCAAGCAGCCAAATTTTCACCCCTCATCGGACATTGGATCGTCGTTCGGTGGAGagaccaccaccaccaccacaaccATAACCAGTCCCAATGTCGTtgtaccgctgctgctggataACAGCTCGAGCGGCGAACGGCCGGAGAAGCTGCGCGCCAAGGAGCTGCTGGTGAATAAGCTTTACGAGTGCAAACTCTGCCCGAAGGGCTTCCGCACCAAGCACGAGTTTCGCACCCATGTCTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAACTCGATTCAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCCGTCGACAGGCGCCGCCACTACAACAACATGGACTGCATTGTTCGCCTACGCTGCATGACGTGCGACGCCAAGGTGGAGACGCATCAGCGTTTTCTCGATCATGTCTATCAAGATCATCTGGGGGGCATAAGCAGCGACAATGCCTCCACTGTGAGTGGATtgggcggcggcggaggcggcggtggcaggagcagcagcagtattGAGAACTCGCCCGGGAAGCGGAGTTTACTAGGGGCTCTCGGGATCGGTGTTGGCTCCCCCGCCGATGAGTCACGCACCGGCAGTGCAGCGGCGACAGCGGCAGCCGTAGCACCCAATCAAACCTCCACGCCAAAGCCGACATCGGGAGGTGGGGCGGGCACAACACCTGGCTCCCTGAATCGTGATGCTGGTGGTGCACCGAAATCGCAGTATTTTTCACGAATGCCCCAGGTATGCCCCATCTGTGGCCAACAgtacaacaactacaacaacgtGCTGCGTCACATGGAATCGAAGCATCCAAACAAACTCCCGGAGACCTACAAATGTGTGCGCTGCGGCCTGGGCTATCCGAGAATCTCGTATCTGCGAGAGCATATGATCAACGTGCATGGCGTGGACAAGAATCGAAATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCCGTGAAGCTGGCCGATGGCAGTACACCGAATGTGTCCACGGGTCGTTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGATGATGACGAGGAGGAGACCGGCAGCATGGCCAAGAAGATACGCCTGGACGatagcagcaacaacagcagtcTGGTGGGTGGGGTGGCCAGCCAGCAAAAGGAATGCCCCATCTGCAATGCACTGTTCAGCAACAATATCGGCCTGTCGAATCACATGCGCTCACATTACACGGCCTCGAGTACCGTGAACGCTGCTCTGGTGGCGGCCAATCGCATGACACCCAAATCCCTGACCATAACCGCCGCCCCAGCCATAGAGACGGTCACATCATCGGCCTCAGTCGATGTTGACGATGACGAGGGCGTTATGCCGCTCGAATCCGGAAATATTATGGCCAGCGTCAGCGGTGGCAGAGGTGTTGCTTCTGCTTCAGCTATTGCTGCTGTGCCTCCTGCCATGGTTAATCAGACGCCTCAAGAGCAGGCCGTCTTTCGTCGCAGCCTGGACCAGGCGGCGGATCGTCGCTTCCGCCGGATGCGTTGCCGCATCTGTCAGCGGCGTTTTAGCTCAAAGAAATCATACCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTTATCAAGTGCAAGCTGTGCAATGCAGAGTTTGCCTACGAGAAGGGTCTCAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATCAAGGATGAGATGATTGTGAAGCAGTTTGAGTGCGATGTCTGTTCGATTGTCTACAGCTCGGAGCTGGAACTGAAGCAGCACAAGCAGAGCGTCCATAAGCTGACATCCGTGTCGGTGTCTGCATCCGCCTCGGCATCGGCTTCGGCTTCTGCCTCGGCATCCACATCCTCGAAAATCGATGATGATTCTATGATGATGGAGGACATCGGTGGCAATAGAAGCCGTcaccatcatcagcagcacAGCAAGGCATCTGGCGATCTGGCCGATCAGTCCATCATCTCCGCCATggctgccaccgccactgccagtgccacaACGACGCCGCTCTACTGGTACCAGTGCAAGTACTGTCCCTCCAACTTTAACACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGATGAGTTCGACTCGAACGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGTCTATGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCGGACCCAATCGAGTGCATGCTGTGCCGCAAGGTGTTCTTTGACCATCAGATGCTGGACAATCATACGCCGACCTGCAACCGTAAGCCAATTACCGCCACGGGGGCGCATCAGCAGGAGCTGCAGACGCAGTCAAATCAGACGCAGGGTCGGGCCGTATTTAGGCATAAGACTggcgacgatgacgacgaggaagagcaacagcagcatcaccagcagcagcaacagcgtaACCATCAGGAGGATGCTGGCGATGGAggagcagtagcagcagcagctgctgccgctgccacatCGAGCGGCACCATCAGCGGTGTCAGTACCAAAAAGATGCGCATACCGGAGGTGGCCTGTACAATTTGTGGCGCCAGATTCACTGATCAGGAGCACTTTAGCAAGCACATACAGAAGCATGAACAGGATCTATATGTGGATAATCCGCTGGCAGCGATGTTCGACGATGGGCCGGCGGATGCGGCCCAATTTAAGGTGGAGGGCCAGAACGAGAACGGGGAATACGCGTGCGATATGTGCACGAAGACATTCCCCCTGGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAACGACGaatatcaacaacaacaacaacaacaattcgGTGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGACGCCCAACCAACaacagaagcaacagcagcagaactCCACGTCCACgccgaacaacaacagcagcagcaacaacagcaacagcagcaagagCAGATCAATGAAGCGTAAACGTGAATTGAAATGCGAATACTGCCCCTCGACATtcatcagcaacaacaacctgCGACGCCACATGTACGAACTGCATAAGCACGAGGTGAGTAGCCTGCCAGCACCGCCCGTGATTGTGGTAGATGACCCGCTCTGCTGTCGACGTTGTGGCAATATCAAATTCGAGACGAAAGAACTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTGCGACCATTTTGTCCCTTCCAATGGGGCTGTGACATGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATGAATCACATCAATAATCATTTGAAGGAGGATGTCATTGTGCCAGTGGCCACACAAGGGGCCATCGACAGAGAACGAGCATCgacagcatcatcatcatcatcgtcagcatcggcatcggctTCGGCATCCGAGGCAACAACATCCAAAGCAAAGGCGTCGTCCGTACTGGCGGAGCAACCCGGTGCCACACTGCAGAAGAAAACGGAGGAAAATGGTGGACTGGATGGAGCGGAGGCGGCGGTAAAGGCAGATGAAGATGATAGCGATATGGAGGATGCCGACAGCTCAGACGGTGATGAAGAAAGCTCTGGCACAGGGGATGAAGACGaagacgatgatgacgacgacgacgacgacgacgacgatgatgacgacgaagATGAGGGCGAAGACGAGGAGGGTGTGCCCCCACCAACACCTGCCACACAACTgttgccacagcagcagcaacacaaacacaaagcCAATATTGACAATGATGAAGATCTCGTCGAAGAAGTGATCAGCTCTGATGATGAAGAGCCTGAGGATGGAGGGGAAGTCGAGAGCGAAAGTCAAACAGAAAGCGAAGAGGACGATGACGAGGATGACGATGAAGACGATGACGACGAGGAAGAGGAACAGggacaggaacaggaacagggcTCGCAGCCCCTGGTGAATGGCAAGTCGAAAGAGCATCAACAGCAAATCGATGAGATATTGCCCAGCTCCGACGACGACGAAGTGGGGGATGGCAATTTAGATGGCCATCTGATGGCCATTGATGACATTATTGAAGAAGAATATGATGAAGACGATGATATGGAGGAGGTGGACGATGGTGCAGTCCATCCAGATCCCGATGATGTCATCGAAGAGGTCGACGACGATGATGCGGATGAGGTGGATGAAGAGCACAATGTCGATGGGGGCGGCACATCCTCGGCCTCATCGTCAGAGAGTGAATCAACATCCACGACCACATCCAATTCGCATTCAACTGGTGAGCGGCGTAAGAAGGCTGGCGACCAGTCGTCAAATCCCAGCTTTACCTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTTCTCCAGTCTCACATCAAAAGCCATTTCCTCAATGGTCCAAAAATCTCTGCCTCACAAGCAACAAGcaatgcaacagcaacagcaacggcaacggcaacgacgACGACTGTGTCGAGCAATTGTAACAACAATGCGTCGACAAAAACCTCGAAGCAGCCCTCCCCAGCCAACAACAACCGACAAAGAAGTTCCGCCGCAGAAATGGGGGCCAGcggtagcagcagcaacagaaattAA
Protein Sequence: MCDTAATTATPVVAATTVGAASVSGTGTSQGTAAATPATAGATPPATTASKPEQQRARQNCCRLCIAPATECISIINSYAADKEPLSTKIHNCVDIKITPQDRLSLQICHACISYLNSWQSFKNRSVSAQNKQRQWLEANKSKLLSYLDLNSAENGGGHQQHHHQNQQQHHSENEIDLEKPSAAQILDGIPSLKKRKSLTVYPLPAIPIKDEPIDTDDDYQMKSLDESDDMVDPTMFLERSEHEGDVPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDSPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLFRVLNALRGKQPNFHPSSDIGSSFGGETTTTTTTITSPNVVVPLLLDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSDNASTVSGLGGGGGGGGRSSSSIENSPGKRSLLGALGIGVGSPADESRTGSAAATAAAVAPNQTSTPKPTSGGGAGTTPGSLNRDAGGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRNSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNDDDEEETGSMAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASSTVNAALVAANRMTPKSLTITAAPAIETVTSSASVDVDDDEGVMPLESGNIMASVSGGRGVASASAIAAVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKQSVHKLTSVSVSASASASASASASASTSSKIDDDSMMMEDIGGNRSRHHHQQHSKASGDLADQSIISAMAATATASATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECMLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELQTQSNQTQGRAVFRHKTGDDDDEEEQQQHHQQQQQRNHQEDAGDGGAVAAAAAAAATSSGTISGVSTKKMRIPEVACTICGARFTDQEHFSKHIQKHEQDLYVDNPLAAMFDDGPADAAQFKVEGQNENGEYACDMCTKTFPLVIALKVHRKWHFRGDSKQNHIDSETTNINNNNNNNSVNNSTSMLRELHAVGLTPNQQQKQQQQNSTSTPNNNSSSNNSNSSKSRSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDDPLCCRRCGNIKFETKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVATQGAIDRERASTASSSSSSASASASASEATTSKAKASSVLAEQPGATLQKKTEENGGLDGAEAAVKADEDDSDMEDADSSDGDEESSGTGDEDEDDDDDDDDDDDDDDDEDEGEDEEGVPPPTPATQLLPQQQQHKHKANIDNDEDLVEEVISSDDEEPEDGGEVESESQTESEEDDDEDDDEDDDDEEEEQGQEQEQGSQPLVNGKSKEHQQQIDEILPSSDDDEVGDGNLDGHLMAIDDIIEEEYDEDDDMEEVDDGAVHPDPDDVIEEVDDDDADEVDEEHNVDGGGTSSASSSESESTSTTTSNSHSTGERRKKAGDQSSNPSFTCDLCQLCFDSQELLQSHIKSHFLNGPKISASQATSNATATATATATTTTVSSNCNNNASTKTSKQPSPANNNRQRSSAAEMGASGSSSNRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480993;
90% Identity: iTF_00580919;
80% Identity: -