Basic Information

Insect: Drosophila subobscura
Gene Symbol: hang
Assembly: GCA_008121235.1
Location: NC:17195682-17212373[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.27 16 5.8 1.0 3 23 298 319 297 319 0.93

2 18 0.18 11 6.3 2.8 3 22 427 446 425 446 0.89

3 18 0.00057 0.034 14.2 3.3 1 22 549 570 549 572 0.90

4 18 0.066 3.9 7.7 0.1 2 21 584 603 583 604 0.93

5 18 0.00066 0.039 14.0 0.2 2 23 741 763 740 763 0.95

6 18 0.0019 0.11 12.5 0.1 1 23 771 794 771 794 0.96

7 18 0.00025 0.015 15.3 0.2 2 23 876 897 875 897 0.97

8 18 0.00027 0.016 15.2 2.9 2 23 1009 1031 1008 1031 0.97

9 18 0.022 1.3 9.2 0.2 2 23 1040 1062 1039 1062 0.95

10 18 0.0042 0.25 11.4 0.2 1 23 1075 1098 1075 1098 0.97

11 18 0.00012 0.0071 16.3 1.1 1 23 1186 1208 1186 1208 0.99

12 18 0.0019 0.11 12.6 0.9 1 23 1216 1239 1216 1239 0.96

13 18 0.33 20 5.5 0.5 2 19 1247 1264 1246 1265 0.92

14 18 3.1e-05 0.0018 18.2 1.4 3 23 1364 1384 1363 1384 0.98

15 18 0.00066 0.039 14.0 0.2 1 23 1419 1441 1419 1441 0.97

16 18 5.9e-05 0.0035 17.3 0.6 2 23 1534 1556 1533 1556 0.93

17 18 0.0043 0.25 11.4 0.5 3 23 1612 1632 1612 1632 0.98

18 18 9.7e-05 0.0058 16.6 2.1 1 23 1987 2009 1987 2009 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.27	16	5.8	1.0	3	23	298	319	297	319	0.93
2	18	0.18	11	6.3	2.8	3	22	427	446	425	446	0.89
3	18	0.00057	0.034	14.2	3.3	1	22	549	570	549	572	0.90
4	18	0.066	3.9	7.7	0.1	2	21	584	603	583	604	0.93
5	18	0.00066	0.039	14.0	0.2	2	23	741	763	740	763	0.95
6	18	0.0019	0.11	12.5	0.1	1	23	771	794	771	794	0.96
7	18	0.00025	0.015	15.3	0.2	2	23	876	897	875	897	0.97
8	18	0.00027	0.016	15.2	2.9	2	23	1009	1031	1008	1031	0.97
9	18	0.022	1.3	9.2	0.2	2	23	1040	1062	1039	1062	0.95
10	18	0.0042	0.25	11.4	0.2	1	23	1075	1098	1075	1098	0.97
11	18	0.00012	0.0071	16.3	1.1	1	23	1186	1208	1186	1208	0.99
12	18	0.0019	0.11	12.6	0.9	1	23	1216	1239	1216	1239	0.96
13	18	0.33	20	5.5	0.5	2	19	1247	1264	1246	1265	0.92
14	18	3.1e-05	0.0018	18.2	1.4	3	23	1364	1384	1363	1384	0.98
15	18	0.00066	0.039	14.0	0.2	1	23	1419	1441	1419	1441	0.97
16	18	5.9e-05	0.0035	17.3	0.6	2	23	1534	1556	1533	1556	0.93
17	18	0.0043	0.25	11.4	0.5	3	23	1612	1632	1612	1632	0.98
18	18	9.7e-05	0.0058	16.6	2.1	1	23	1987	2009	1987	2009	0.98

Sequence Information

Coding Sequence: ATGTGCGACacggcggcaacaacaactacaacagtTGCGGCAACTACAACGGTGGCAGCAGCGTCGTCGGTGTCTGGCCCTGGAACGAGCCAGAGTCAGGGAACGGCAGCGGCtacagcagcgactgcaggaGCCACACCGCCAGCTACAACCACAGCGAAacccgagcagcagcagcgggcgcGACAAaactgctgccgcctctgcaTTGCCCCGGCCTCGGAATGCATTTCGATCATCAATAGCTATGCGGCCGACAAGGAGCCGCTCTCTACAAAAATCCACAACTGTGTGAACATCAAGATAACACCGCAAGATCGGCTGTCACTGCAGATCTGTCACGCCTGCATCAGCTACTTAAACTCGTGGCAGAGCTTTAAGAATCGCTCGGTGAGCGCACAGAGCAAACAGCGTCAGTGGCTGGAGGCCAACAAGAGCAAGCTGCTCAGCTATTTGGATTTGAACAGTGCCGAGAATGGAGGAGgtcatcagcagcaccaacagaaccagtcacagcagcagcatcagcagcatcattcGGAGAATGACATCGATTTGGAGAAGCCATCGGCCGCTCAAATATTGGACGGCATACCATCGCTGAAGAAACGCAAATCCCTAACAGTCTATCCACTGCCCGCTATACCCATCAAGGATGAGCCCATTGACACCGATGATGACTATCAAATGAAATCGTTGGACGAATCCGAAGACATGGTCGATCCCACAATGTTCCTAGAACGCTCCGAGCACGAGGGCGATATACCACTAATGACCTCCGACTATGATTATACGGCACAGCATGGTGTGAATGCAGAGACAGCGGCCGCCTCGTTGCCGCCTAATGCTGTGGCCAATGTGGCCGCCGCCGGGGACTCGAAGGTGGCCAGCTGCCGGGCATGCAGTCTTCAGTTTTCGACACGTGCCAATGCCCGTCGCCACGAGCGGAATTTGCACCCAAATCTATTCCAATTGTCGACAGACTCGCCCAACAATACGCCCATCACAAAGCCCACCCCGGCACTGGCGGCAGCACTGGAGATACAGCGTGCCGCCGCCGAGGCGGCCACCGAGGAGGCCAGCAAGGCTGCCGGCGCTGCCGGTGGCAATATATCGACCCAAAAGTATCGCCAGGTGGTCATGAATGCCTTCATCAAGTGCGAGGGCGGCGGCTTCAACTACGACAGTCCCGAGCAATATCAGCCGCTGCTCACCCGCGACAAGGTGGAGTTTATCGAGCAGAATTACGAATTCCTCGAGCAGTACCAGACGATGacatgccgctgctgcgacAAATACTTCACTACGTACAAGAACTTTATGGCGCATGTGCGCAAAAAGTATCCGCTGTTGCCGCGTAATCTCTGCTTCAACTGCCTCAAGATGAACGAATCGAAGGCGCTCTTCATATCGCATCTCAAGAAGCGCAACTGCATCAATCTGTATCGCGTGCTGAACGCACTGCGCGGCAAGCAGCCCAACTTCCATCCCTCGACGTCTGACATGGGATCGTTTGGTGGCGAGACGAGCAACACAGCGATCACCAGTCCCACTGTCGTTGTGGCGCCACTGCTGATGGATAACAGCTCGAGCGGCGAGAGGCCAGAGAAGCTGCGcgccaaggagctgctggtgaATAAGCTTTACGAGTGCAAGCTCTGCCCGAAGGGTTTCCGCACCAAGCACGAGTTCCGCACTCATGTGTACGACAAGCATGCGGACGTGCAGCGCAAGGATAACAATTCGATTCAGTGCAGCTTCTGCGGCCTGGACTTTGCCGATCCCGTGGACAGGCGACGGCACTACAACAACATGGACTGCATTGTCCGCCTGCGCTGCATGACGTGCGATGCGAAAGTGGAGACGCATCAGCGTTTCCTCGATCATGTCTATCAGGATCATTTGGGTGGCATCAGCAGCGACAATGCCTCCACGGCGAGCGGATTggtcggcagcagcagcattgaaaACTCACCTGGCAAGCGGAGTCTATTGGGCGCCCTTGGTATTGGTGTTTGCTCTCCCGCCGATGAGTCACGCAGCGGCagtgcggcagcggcagccgcaggagGATCAGCAGGGGCAGCACCCAATCAAACATCAACGCCAAAGCCAACATCGGGAGGTGGTGGAGTGGCGTGCACAACAcctggcggcagcggcggctccCTAAATCGTGACAGCGCACCCAAGTCGCAGTATTTCTCACGCATGCCACAGGTATGCCCCATCTGTGGGCAGCAgtacaacaactacaacaacgtGCTGCGGCACATGGAATCGAAGCATCCAAACAAACTGCCCGAAACATACAAATGCGTCCGCTGCGGCCTGGGCTATCCACGAATCTCGTATCTCCGCGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGCCATTCCGGTGGCTTTGAGTATATTGTGAATGCGGATGCCGTCAAGCTGGCCGATGGCAGTACACCGAACGTGTCCACGGGTCGCTACGACTACGTGATGAAGGATCTGATGTCAATAACAAATGatgacgacgaggaggagactggcAGCGTGGCCAAGAAGATACGCCTGGATGATAGCAGCAATAACAGCAGCCTGGTGGGCGGCGTGGCCAGCCAGCAAAAGGAATGCCCCATCTGCAATGCGCTCTTTAGCAACAATATTGGCCTGTCCAACCACATGCGCTCCCACTACACGGCCTCGAATTCGGTGAATGCCGCTCTGGTGGCTGCCAATCGCATGACGCCCAAGTCGCTGACGATAACCGCCACACCAGCCACAGAGACGGTCACCTCATCGGCAGCCTCACTCGATGTGGACGATGATGAGGGGATTATAGCGCTTGAGACGGCACAGATAATGGCCAGCGTGAATGCTGCCAGAGCGGCTAGaattgctggtgctgctggtgctggtgctgctgcatcttCTGTGCCGCCTGCCATGGCCAATCAGACGCCCCAGGAGCAGGCAGTCTTTCGTCGCAGCTTGGATCAGGCGGCGGATCGTCGCTTCCGGCGCATGCGCTGCCGCATCTGTCAGCGGCGTTTCAGCTCAAAGAAATCGTATCGCTATCACATGCTCACCGACCATCAGGTGCAGAATGTGCAGTTCATCAAATGCAAGCTGTGCAATGCAGAGTTCGCCTACGAAAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCATGGCCGTGCGATCAAGGACGAGATGATTGTGAAGCAATTCGAGTGCGATGTCTGCTCGATTGTGTACAgctcggagctggagctgaagcagcacAAGAAGAGTGTCCATAAGTTGACATCATCCGtctcggtgtcggtgtcggcaTCGGCATCCGCCTCGGCATCGGCCTCGGCAtcagcctctgtctctgcctctgcgtccACATCCTCCAAAATGGATGACGATTCCATGATGCTGGAGGAGATGGGCGGCAATAGAAGCCGCcaccatcaacatcagcaccacagcagcaaGGCGTCTGGCGATACGGTCGATCAGTCCATCATTTCTGGtgcggctgccacagccacaacgacGCCGCTGTATTGGTACCAATGCAAATACTGTCCCTCTAACTTTAACACCAACAAGAAGCTGGCCATCCACATAAACTCGCACGACGAGTTCGACTCGAATGATTATTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGTCTTTGGGTTCATCGCTACAAAAAGCATCCGCAGGTGCCCGACCCCATTGAGTGCACGCTGTGCCGCAAGGTGTTCTTCGATCATCAGATGCTGGACAATCATACGCCCACCTGCAACCGCAAGCCGATTACCGCCACTGGGGCgcatcagcaggagctgctgacGCAGGCAAATCAATCGCAGGGTCGTGCCATATTCCGACACAAGACtggcgacgatgatgatgaggaagacctgcagcagcatccgcaacagctgcagcaacagcaacagaggcgTAACCATCAGGATGCAGGCGATGCAGTGGCAACAgtgacagcagcaactgctgcagcggcagccacatcgagtggtggcggtggcggcagtaGCAAAAAGATGCGCATACCGGAGGTGGCATGCACCATTTGTGGTGCACGCTTCACCGATCAGGAGCACTTTAGCAAGCACATACAGAAGCATGAACAGGATCTGTATGTGGATAACCCATTGGCGGCAATGTTCGATGATGGGCCAGCGGATGCGGCACAGTTCAAGGTCGAGGGCCAGAACGAGAACGGGGAATATGCGTGCGATATGTGCACGAAGACATTCCCCCAGGTGATTGCACTCAAAGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAACCACATCGACAGCGAAGCGACGaatatcaacaacaacaacaacaatttggtGAACAACTCCACATCGATGCTACGGGAGCTGCATGCAGTGGGTCTGACGCccaatcaacagcagcagcagcagcagcagagccaacaGCAGAATTCCACGTCCACgccgaacaacaacaacaacaggagcagcagcaacaacaacaacaacagcagcagcagcagcagcaggagcaaatcGATGAAACGTAAACGTGAATTGAAATGCGAATACTGCCCATCGACCTTCATCAGTAACAACAACCTGCGACGACACATGTATGAGCTGCACAAGCATGAGGTGAGTAGCCTGCCAGCACCGCCAGTGATTGTGGTGGATGAGCCGCTCAGCTGCCGACGCTGTGGCGACATTCAATTCGAGACAAAAGAACTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTGCGACCCTTTTGTCCCTTCCAATGGGGCTGTGACATGTGCGGCGAGTACTTGTCGCGCAAAGAGAAGCTCATGAATCACATCAACAATCATTTGAAGGAGGATGTCATTGTGCCAGTGGCCACACAAGCGGCCATTGACAGAGAACgtgcagcatcatcatcgtcatcctcagcagcatcatcatccgAGGCAACAACATCGAAAGCAAAGAcatcagcctcagcatcagcatccgtGTTGGTTGAGCAGAAGCCATCCGGCGCAGCGTTGCAAAAGAAAACGGAAGAGAATGGTGGACTGGATGCAGCGGTGgcgacagcggcagagtcggTGAAGGCAGGCGAAGATGATAGCGAAATGGAGGATGTCGACAGCTCAGACGCTGATGAAGAAAGCTCTGGCACAGGGGATGAGGaagacgacgatgatgatgatggcgaagaggacgatgacgacgacgatgatgaagaagatgagctgcaggacgacgacgacgacgacgatgatgatgaagaagaGGGTGAGGGTGAAGATGAAGAGGGTGTGCCCCCACCAACACCTGCCGCACAATTGTTGCAACacaaacagccacaacaacaacaacaacacaaagcCAATAGCAATAATATTGACAGCGTTGATGATCTCGTCGAGGAAGTGAACAGCTCTGATGATGAGGAGCCCGATGGCGAAGTAGGGAGCGAAAGTCAAACCCAAagcgacgaggacgatgaAGAAGATGATGAAGCTGACATTggtgaggaggaggaggatgaggagctgGGTTCGGCCCAGCCCCTGACTAATGGCAAGTCGAAAGAGCATAATGCGACGCCCCAACAGCAAATGGAGCAAATTTTGCCCAGCTCTGACGAGGAAggcgagaacgagaacgagaacgacaacgacaacgtaGAGGAAGATGGTGGCAATGCAGATGGACATACATTGGCCATTGAAGACATTATTGAAGAAGAATATGATGAAGACGATGATGTGGAGGAGGTATACGATGAGCAGAATGCTGATGGTGGTGCCACATCGTCGGTATCATCCTCAGAGAGCGAATCAACATCCTCGACCACATCCCATTCGCATTCAACTGGTGAGCGGCGTAAGAAGGCTGGCGGCGATCAGTCGTCGAATCCCAGCTTCACCTGTGATCTCTGTCAACTTTGTTTCGATTCCCAGGAGCTTCTACAGTCTCACATCAAAAGTCATTTTCGCAATGGCCCAAAAATCTCTGCCCCacaagcaacagccacagcagccgcaaccgcaacggcaacggcaacggtaACGACGGTTGCAACGGCGACGACTGTTCCCAGTAGTTGTAACAACAATGGCTCGACAAATTCCTCCTCAAAGCACTCTCCAGCAGCGGCCAGAGGTGGCAGCAGTAGCAATTGA
Protein Sequence: MCDTAATTTTTVAATTTVAAASSVSGPGTSQSQGTAAATAATAGATPPATTTAKPEQQQRARQNCCRLCIAPASECISIINSYAADKEPLSTKIHNCVNIKITPQDRLSLQICHACISYLNSWQSFKNRSVSAQSKQRQWLEANKSKLLSYLDLNSAENGGGHQQHQQNQSQQQHQQHHSENDIDLEKPSAAQILDGIPSLKKRKSLTVYPLPAIPIKDEPIDTDDDYQMKSLDESEDMVDPTMFLERSEHEGDIPLMTSDYDYTAQHGVNAETAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAEAATEEASKAAGAAGGNISTQKYRQVVMNAFIKCEGGGFNYDSPEQYQPLLTRDKVEFIEQNYEFLEQYQTMTCRCCDKYFTTYKNFMAHVRKKYPLLPRNLCFNCLKMNESKALFISHLKKRNCINLYRVLNALRGKQPNFHPSTSDMGSFGGETSNTAITSPTVVVAPLLMDNSSSGERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKVETHQRFLDHVYQDHLGGISSDNASTASGLVGSSSIENSPGKRSLLGALGIGVCSPADESRSGSAAAAAAGGSAGAAPNQTSTPKPTSGGGGVACTTPGGSGGSLNRDSAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVSTGRYDYVMKDLMSITNDDDEEETGSVAKKIRLDDSSNNSSLVGGVASQQKECPICNALFSNNIGLSNHMRSHYTASNSVNAALVAANRMTPKSLTITATPATETVTSSAASLDVDDDEGIIALETAQIMASVNAARAARIAGAAGAGAAASSVPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSELELKQHKKSVHKLTSSVSVSVSASASASASASASASVSASASTSSKMDDDSMMLEEMGGNRSRHHQHQHHSSKASGDTVDQSIISGAAATATTTPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPIECTLCRKVFFDHQMLDNHTPTCNRKPITATGAHQQELLTQANQSQGRAIFRHKTGDDDDEEDLQQHPQQLQQQQQRRNHQDAGDAVATVTAATAAAAATSSGGGGGSSKKMRIPEVACTICGARFTDQEHFSKHIQKHEQDLYVDNPLAAMFDDGPADAAQFKVEGQNENGEYACDMCTKTFPQVIALKVHRKWHFRGDSKQNHIDSEATNINNNNNNLVNNSTSMLRELHAVGLTPNQQQQQQQQSQQQNSTSTPNNNNNRSSSNNNNNSSSSSSRSKSMKRKRELKCEYCPSTFISNNNLRRHMYELHKHEVSSLPAPPVIVVDEPLSCRRCGDIQFETKELWIEHKLADAKVVRPFCPFQWGCDMCGEYLSRKEKLMNHINNHLKEDVIVPVATQAAIDRERAASSSSSSAASSSEATTSKAKTSASASASVLVEQKPSGAALQKKTEENGGLDAAVATAAESVKAGEDDSEMEDVDSSDADEESSGTGDEEDDDDDDGEEDDDDDDDEEDELQDDDDDDDDDEEEGEGEDEEGVPPPTPAAQLLQHKQPQQQQQHKANSNNIDSVDDLVEEVNSSDDEEPDGEVGSESQTQSDEDDEEDDEADIGEEEEDEELGSAQPLTNGKSKEHNATPQQQMEQILPSSDEEGENENENDNDNVEEDGGNADGHTLAIEDIIEEEYDEDDDVEEVYDEQNADGGATSSVSSSESESTSSTTSHSHSTGERRKKAGGDQSSNPSFTCDLCQLCFDSQELLQSHIKSHFRNGPKISAPQATATAAATATATATVTTVATATTVPSSCNNNGSTNSSSKHSPAAARGGSSSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00480993;
90% Identity: iTF_00515036;
80% Identity: -