Dano011956.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila anomalata
Gene Symbol
Hr39
Assembly
GCA_035046425.1
Location
JAWNNY010001750.1:2147643-2150377[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.093 9.5e+02 -0.9 1.1 97 166 143 216 85 228 0.52
2 3 2 2e+04 -5.7 9.9 59 176 247 375 223 382 0.52
3 3 2.3e-101 2.3e-97 327.2 4.0 1 408 445 809 445 809 0.90

Sequence Information

Coding Sequence
ATGCCGAACATGTCCAGCATCAAGGCGGAGCAGCAAAGTGCCCCCCTGGGCACTACAGGAAGCTTTCAGCTACCGAGCAACAGCAATGCAACCACGATTCCAGCTGGAGCGGCTGGAGGAGCCACCACCCCCTCCCGGCACAACGTCTCCGTGACGAACATTAAGTGCGAGCTGGACGAGCCACCCACGCCCAACGGCAACCTGGTGCCGGTAATAGCCAACTATGAACTCCACTCGGGCAGCATACTTATACCGCTGACCGGACAACAGAGCCAGGAGGACGAGTCCGACTCCGAGGCGGAACTGACGAACATTGAAAACTTGAAGGTGCGACGACGGGCCTCGGACAAGAACGGTCCGCGGCCCATGTCCTGGGAGGGGGAGCTGAGCGAGCCGGAGGCCGACGGCGGGGAGGAGCCCATGGAGACCGAGCCGACGATCAAAAGGGAGATCCTAGCGTCTCATGCTGCCACGACCATGCAGCCCATTAAGACCGAGCTGGAGAACATCGACGGCGAACTgcatcaccagcagcagcaggggaAGCCGTACACGCTGTCCACCTCCACGCCGCACTCCGGCCCGAAGCTGAAGCTGGCGCCGACCCAGAGCGACCCGATTAACCTTAAGTTCGAGCCACCGCTGGGGGACAACTCACCGCTCCTGGCGGCCCGCAGCAAGTCGAGCAGCGGCGGCCACCTGCCACTGCCTGCGAATCCCAGTCCGGACTCCGCCATACATTCCGTCTACACGCACAGCTCGCCCTCCCAGTCCCCGCTGACTTCCCGGCACGCCCCCTACACGCCCTCGCTCAGCCGGAACAACAGCGACGCCTCCCACAGCAGCTGCTACAGCTACAGCTCGGAGTTCAGTCCCACCCACTCGCCGATTCAGGCGCGTCATGCCACGCCCAGCGGCGTCCTTTACGGCAACGGGAGTCTGCACCACCACAGCGTGCTGTACCGACCGCTCAAGATGGAGGCTTCCTCCACGGCCTCATCCGGAAGCCACGAGGCGCAGAACCTGAGCATGGACTCGGTCTGCAGCAGCTTGGACGTGAGCTCCGGCTCATCCCTACCCGCTTCTCCGGCTGGCATTTCGCGCCAACAACTCATCAACTCGCCGTGCCCCATTTGCGGCGACAAAATCAGTGGCTTCCATTACGGCATCTTCTCGTGCGAGTCCTGCAAGGGATTCTTCAAGCGCACTGTCCAAAATCGAAAGAACTACGTCTGCGTGCGGGGTGGACCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGCCCGGCCTGCAGGTTCGAAAAGTGCCTGCAAAAGGGCATGAAACTGGAGGCCATTCGGGAGGACAGGACGCGTGGCGGTCGGTCCACCTATCAGTGCTCCTACACGTTACCCAATTCGATGCTCAGCCCGCTGGTGAGTCCGGACCAGGCGACAGGATCGGCAACGatgcagcaccagcagccgAATCAGCAACAGAGACTTCATCAACTGAATGGGTTTGGTGGTACATCCCTGTCCACCTCGGTTTCCCTGCCCGCCAGCCCCAATCTGGGGGCCTCCATCAAGGTGGAGGAACCGGTTGATACAGCCAAGCACCAGATCCAACGAATAGGAAGCATTCCGCCACTTCTGAAGgAAATTATGGATGTTGAACATCTATGGCAGTACACCGACGCAGAGCTGGCCCGCATCAATCAACCGCTGTCTGCCTTCGCCTCCGGAAGCTCCTCATCGTCCGCGGCTACCTCCGCCACCCACGGACAACCGCCACAGCAACCACAAGTGACCAATCCACTGCTGGCCAGTGCCGGTCTATCATCCAATGGAGAGAACGCCAATCCCGATCTGATCGCCCATCTGTGCAACGTGGCCGACCACCGTCTCTATAAGATTGTAAAATGGTGCAAGAGTTTGCCGCTCTTTAAGAATATATCGATCGATGACCAGATCTGCTTGCTAATCAATTCCTGGTGTGAGCTATTGCTCTTCTCCTGCTGTTTCCGATCCATCGACACTCCTggggaaataaaaatgtcacaAGGCAGAAAGATAACCCTCTCGCAGGCCAAATCAAATGGTTTGCAGacCTGCATTGAAAGAATGCTTAATCTGACAGATCACTTAAGGCGTCTGCGAGTAGATCGCTATGAATACGTTGCCATGAAGGTGATTGTGCTGCTGCAGTCAGACACCACGGAGTTGCAGGAGGCTGTCAAGGTGCGGGAGTGCCAGGAGAAGGCCTTGCAGAGCTTACAGGCCTATACCCTGGCCCACTATCCCGAAACTCCTTCGAAGTTTGGCGAACTCCTGCTCCGTATTCCCGATCTGCAGCGTACATGCCAGCTTGGAAAGGAGATGCTAACGATCAAAACACGCGATGGGGCCGATTTCAACTTGCTGATGGAGCTATTACGCGGAGAACATTGA
Protein Sequence
MPNMSSIKAEQQSAPLGTTGSFQLPSNSNATTIPAGAAGGATTPSRHNVSVTNIKCELDEPPTPNGNLVPVIANYELHSGSILIPLTGQQSQEDESDSEAELTNIENLKVRRRASDKNGPRPMSWEGELSEPEADGGEEPMETEPTIKREILASHAATTMQPIKTELENIDGELHHQQQQGKPYTLSTSTPHSGPKLKLAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHATPSGVLYGNGSLHHHSVLYRPLKMEASSTASSGSHEAQNLSMDSVCSSLDVSSGSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLVSPDQATGSATMQHQQPNQQQRLHQLNGFGGTSLSTSVSLPASPNLGASIKVEEPVDTAKHQIQRIGSIPPLLKEIMDVEHLWQYTDAELARINQPLSAFASGSSSSSAATSATHGQPPQQPQVTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPETPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH