Basic Information

Insect: Drosophila ercepeae
Gene Symbol: Hr39
Assembly: GCA_018150545.1
Location: JAECWL010000189.1:11772531-11775285[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.13 1e+03 -1.4 0.2 106 161 154 215 91 232 0.62

2 3 1.6 1.3e+04 -5.0 7.5 52 176 258 378 237 384 0.55

3 3 6.4e-100 5e-96 322.4 5.2 1 408 448 813 448 813 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.13	1e+03	-1.4	0.2	106	161	154	215	91	232	0.62
2	3	1.6	1.3e+04	-5.0	7.5	52	176	258	378	237	384	0.55
3	3	6.4e-100	5e-96	322.4	5.2	1	408	448	813	448	813	0.83

Sequence Information

Coding Sequence: ATGCCGAACATGTCCAGCATCAAGGCGGAGCAACAGAGTACGCCCCTGGGCAGTACCGGGAGCTTTCAACTACCGAACAACAGCAATGCAACAATGACGATGCCCCCGGGAGGAGGAACTGCTGGAGGTGCAACCCCTTCCCGGCACAATGTATCCGTGACGAACATTAAATGCGAGCTGGACGAACCGTCGACGCCCAATGGGAACCTGGTGCCGGTTATCGCCAACTATGAACTCCATTCGGGCAGCCTGCTCATACCGCTGACCGGACAACCAACAAGCCAGGAGGATGAGTCCGACTCCGAGGCAGAACTGACAAACATTGAGAACTTGAAGGTGCGGCGACGGGCCTCGGACAAGAACGGACCCCGACCCATGTCCTGGGAGGGGGAGCTGAGTGAAGCAGAGGCCGATGGCGGGGAAGAGCCCATGGAAACCGAGCCGACGATCAAAAGAGAGCTCCTAGCATCGCATCCTGCCACCACCCTGCAGCCCATCAAGACCGAGCTGGAGAACATTGACGGGGAGCTGCACCAGCAGCAGGGAAAGCCCTACACGTTGTCCAGTTCCACGCCGCACTCCGGTCCCAAGCTGAAGCTGGCGCCCACCCAGAGCGATCCGATTAATCTTAAGTTCGAGCCGCCGCTGGGCGAGAACAACTCCCCGCTTCTGGCAGCCCGCAGCAAGTCCAACAGCGGTGGTCACCTGCCGCTGCCCGCCAATCCCAGTCCCGACTCCGCCATACATTCCGTCTACACGCACAGCTCGCCCTCCCAGTCGCCGCTGACCTCCCGGCACGCGCCCTACACGCCCTCCCTCAGCCGCAACAACAGCGACGCCTCCCACAGCAGCTGCTACAGCTACAGCTCCGAGTTCAGTCCCACCCACTCACCGATTCAGGCGCGTCATGCTCCGCCCAGTGGAGTCCTGTACGGGAACGGGGGTCTGCACCACCACAGCGTCCTGTACCGACCGCTCAAGATGGAAGCATCTTCCACCGCCTCTTCGGGAAGTCACGAAGCCCAGAATCTTAGCATGGATTCGGTGTGCAGCAGCCTGGATGTGGGCAGCTCGGGATCATCGCTTCCCGCCTCGCCGGCTGGCATTTCACGGCAACAACTCATCAACTCTCCGTGTCCCATTTGCGGGGACAAGATCAGTGGCTTCCATTACGGGATATTCTCGTGCGAGTCCTGCAAGGGATTCTTCAAGCGAACCGTACAGAACCGGAAGAACTACGTCTGCGTAAGGGGTGGACCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGTCCGGCTTGCAGGTTCGAGAAGTGCCTGCAAAAGGGCATGAAACTAGAAGCTATTCGCGAGGACAGGACACGGGGCGGTCGCTCCACCTACCAGTGCTCCTACACGCTGCCCAACTCGATGCTCAGCCCGCTGGTGAGTCCCGACCAGGCGACACCATCTCCAGGGGTTGCTAACCAGCAGCAGCAGCAGCCAAATCAGCAACAGAGACTTCATCAGTTGAACGGATTTGGTGGCACTTCGGTTTCCCTGCCTGCCAGCCCCAATCTTGGAGCTTCAATCAAGCTGGAAGAATCGGTTGATCCCGTAAAGCAGACCCAACGCACAGGAAGCATTCCGCCACTTCTAAAGGAAATTATGGATGTTGAACATCTGTGGCAGTACACCGACGCAGAGCTGGCCCGCATCAACCAACCGCTGTCTGCCTTCGCATCCGGAAGCTCCTCGACAACGTCCTCGTCCTCCGCTTCCCCAGCCGCCCACGGACAACCCCCACAGCAGCCACAACTGACCAATCCACTGCTGGCCAGTGCCGGTCTATCGTCCAACGGAGAGAACGCCAACCCCGATCTGATCGCCCATCTGTGCAATGTTGCCGACCATCGTCTCTATAAGATTGTTAAATGGTGCAAAAGCTTGCCCCTCTTCAAGAACATTTCGATCGATGATCAAATATGTTTGCTAATCAATTCTTGGTGTGAGCTTTTGCTCTTCTCCTGCTGTTTTCGTTCCATCGACACTCCAGGCGAAATAAAAATGTCACAAGGCAGAAAGATAACCCTCTCGCAGGCCAAGTCCAATGGTTTGCAGACCTGCATTGAAAGAATGCTAAATCTGACAGATCACTTAAGACGTTTGCGCGTGGATCGCTATGAATACGTGGCCATGAAAGTGATTGTGCTGTTGCAGTCAGATACAACGGAGTTGCAGGAGGCTGTCAAGGTGCGAGAGTGCCAGGAAAAGGCATTGCAGAGCTTACAGGCCTATACCCTGGCCCACTATCCGGAAACTCCGTCAAAGTTTGGCGAACTCCTGCTACGCATTCCCGATCTGCAGCGTACGTGCCAGCTTGGAAAGGAGATGCTGACGATCAAAACTCGTGATGGGGCTGATTTCAATTTGCTGATGGAACTACTACGCGGAGAACATTGA
Protein Sequence: MPNMSSIKAEQQSTPLGSTGSFQLPNNSNATMTMPPGGGTAGGATPSRHNVSVTNIKCELDEPSTPNGNLVPVIANYELHSGSLLIPLTGQPTSQEDESDSEAELTNIENLKVRRRASDKNGPRPMSWEGELSEAEADGGEEPMETEPTIKRELLASHPATTLQPIKTELENIDGELHQQQGKPYTLSSSTPHSGPKLKLAPTQSDPINLKFEPPLGENNSPLLAARSKSNSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPSGVLYGNGGLHHHSVLYRPLKMEASSTASSGSHEAQNLSMDSVCSSLDVGSSGSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLVSPDQATPSPGVANQQQQQPNQQQRLHQLNGFGGTSVSLPASPNLGASIKLEESVDPVKQTQRTGSIPPLLKEIMDVEHLWQYTDAELARINQPLSAFASGSSSTTSSSSASPAAHGQPPQQPQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPETPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00483029;
90% Identity: iTF_00477364;
80% Identity: iTF_00504036;