Basic Information

Insect: Drosophila ananassae
Gene Symbol: Hr39
Assembly: GCA_017639315.1
Location: CM029942.1:43482837-43485574[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.11 6.3e+02 -0.6 1.0 96 168 142 218 78 230 0.53

2 3 3 1.7e+04 -5.4 9.0 52 176 256 375 233 382 0.57

3 3 1e-100 5.7e-97 325.6 4.4 1 408 445 810 445 810 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.11	6.3e+02	-0.6	1.0	96	168	142	218	78	230	0.53
2	3	3	1.7e+04	-5.4	9.0	52	176	256	375	233	382	0.57
3	3	1e-100	5.7e-97	325.6	4.4	1	408	445	810	445	810	0.89

Sequence Information

Coding Sequence: ATGCCGAACATGTCCAGCATCAAGGCAGAGCAGCAAAGTGCCCCCCTGGGCACTACAGGAAGCTTTCAGCTACCGAGCAACAGCAATGCAACCACGATACCAGCTGGAGCGGCTGGAGGAGCCACCACCCCCTCCCGGCACAACGTCTCCGTGACGAACATTAAGTGCGAGCTGGACGAGCCACCCACGCCCAACGGCAACCTGGTGCCGGTAATAGCCAACTACGAACTCCACTCGGGCAGCATACTTATACCGCTGACCGGACAACAGAGCCAGGAGGACGAGTCCGACTCCGAGGCGGAACTGACGAACATTGAGAACTTGAAGGTGCGACGACGGGCTTCGGACAAGAACGGTCCGCGGCCCATGTCCTGGGAAGGGGAGCTGAGCGAGCCGGAGGCCGACGGCGGGGAGGAGCCCATGGAGACCGAGCCGACGATCAAAAGGGAGATCCTGGCGTCTCATGCTGCCACGACCATGCAGCCCATTAAGACCGAGCTGGAGAACATCGACGGCGAACTGCACCACCAGCAGCAGCAGGGGAAGCCGTACACGCTGTCCACCTCCACGCCGCACTCCGGCCCGAAGCTGAAGCTTGCGCCGACCCAGAGCGACCCGATTAACCTTAAGTTCGAGCCACCGCTTGGGGACAACTCACCGCTCCTGGCGGCCCGCAGCAAGTCGAGCAGCGGCGGCCACCTGCCACTGCCTGCGAATCCCAGTCCGGACTCCGCCATACATTCCGTCTACACGCACAGCTCGCCCTCCCAGTCCCCGCTGACGTCCCGGCACGCCCCCTACACGCCCTCGCTCAGCCGGAACAATAGCGACGCCTCCCACAGCAGCTGCTACAGCTACAGCTCGGAGTTCAGTCCCACCCACTCGCCGATTCAGGCGCGTCATGCCCCGCCCAGCGGCGTCCTTTACGGCAACGGGAGTCTGCACCACCACAGCGTGCTGTACCGACCGCTCAAAATGGAGGCTTCGTCCACCGCCTCATCCGGAAGCCACGAGGCGCAGAACCTGAGCATGGACTCGGTCTGCAGCAGCCTGGACGTGAGCTCCGGCTCATCCCTACCCGCTTCTCCGGCTGGCATTTCGCGCCAACAACTCATCAACTCGCCGTGCCCCATTTGCGGCGACAAAATCAGTGGCTTCCATTACGGCATCTTCTCGTGCGAGTCCTGCAAGGGATTCTTCAAGCGCACTGTCCAAAATCGAAAGAACTACGTCTGCGTGCGCGGTGGACCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGCCCGGCCTGCAGGTTCGAAAAGTGCCTGCAAAAGGGCATGAAACTGGAGGCCATTCGGGAGGACAGGACGCGTGGCGGTCGGTCCACCTATCAGTGCTCCTACACGTTACCCAACTCGATGCTCAGCCCGCTGGTGAGTCCGGACCAGGCGACCGGATCGGCAACGATGCACCAGCAGCAACAGCCGAATCAGCAACAGAGACTTCATCAACTGAATGGGTTTGGTGGTACATCACTGTCCACCTCGGTTTCCCTGCCCGCCAGCCCCAATCTGGGGGCCTCCATCAAGGTGGAGGAACCGGTTGATACAGCCAAGCACCAGATCCAACGAATAGGAAGCATTCCGCCACTTCTGAAGGAAATTATGGATGTTGAACATCTATGGCAGTACACCGACGCAGAGCTGGCCCGCATCAATCAACCGCTGTCTGCCTTCGCCTCCGGAAGCTCCTCATCGTCCGCAGCTACTTCCGCCAGCCACGGACAACCGCCACAGCAACCACAAGTGACCAATCCACTGCTGGCCAGTGCCGGTCTATCATCCAACGGAGAGAACGCCAATCCCGATCTGATCGCCCATCTGTGCAACGTGGCCGACCACCGTCTCTATAAGATTGTAAAATGGTGCAAGAGTTTGCCCCTCTTTAAGAATATATCGATCGATGACCAGATCTGCTTGCTAATCAATTCCTGGTGTGAGCTATTGCTCTTCTCCTGCTGTTTCCGATCCATCGACACTCCTGGAGAAATAAAAATGTCACAAGGCAGAAAGATAACCCTCTCGCAGGCCAAATCAAATGGTTTGCAGACCTGCATCGAAAGAATGCTTAATCTGACAGATCACTTAAGGCGCTTGCGAGTCGATCGCTATGAATACGTTGCCATGAAGGTGATTGTGCTGCTGCAGTCAGACACCACGGAGTTGCAGGAGGCTGTCAAGGTGCGGGAGTGCCAGGAGAAGGCCTTGCAGAGCTTACAGGCCTATACCCTGGCCCACTATCCCGAAACTCCTTCAAAGTTTGGCGAACTCCTGCTCCGTATTCCCGATTTGCAGCGTACATGCCAGCTTGGAAAGGAGATGCTAACGATCAAAACACGCGATGGGGCCGATTTCAACTTGCTGATGGAGCTATTACGCGGAGAACATTGA
Protein Sequence: MPNMSSIKAEQQSAPLGTTGSFQLPSNSNATTIPAGAAGGATTPSRHNVSVTNIKCELDEPPTPNGNLVPVIANYELHSGSILIPLTGQQSQEDESDSEAELTNIENLKVRRRASDKNGPRPMSWEGELSEPEADGGEEPMETEPTIKREILASHAATTMQPIKTELENIDGELHHQQQQGKPYTLSTSTPHSGPKLKLAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPSGVLYGNGSLHHHSVLYRPLKMEASSTASSGSHEAQNLSMDSVCSSLDVSSGSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLVSPDQATGSATMHQQQQPNQQQRLHQLNGFGGTSLSTSVSLPASPNLGASIKVEEPVDTAKHQIQRIGSIPPLLKEIMDVEHLWQYTDAELARINQPLSAFASGSSSSSAATSASHGQPPQQPQVTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPETPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00483029;
90% Identity: iTF_00477364;
80% Identity: iTF_00475975;