Basic Information

Insect: Drosophila atripex
Gene Symbol: Hr39
Assembly: GCA_035045925.1
Location: JAWNOP010000070.1:13818857-13821623[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.19 1.7e+03 -1.9 0.1 107 165 161 213 85 225 0.61

2 3 1.3 1.2e+04 -4.7 10.1 52 177 254 375 222 381 0.62

3 3 5.9e-102 5.3e-98 329.1 4.4 1 408 444 812 444 812 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.19	1.7e+03	-1.9	0.1	107	165	161	213	85	225	0.61
2	3	1.3	1.2e+04	-4.7	10.1	52	177	254	375	222	381	0.62
3	3	5.9e-102	5.3e-98	329.1	4.4	1	408	444	812	444	812	0.90

Sequence Information

Coding Sequence: ATGCCGAACATGTCCAGCATCAAGGCGGAGCAGCAAAGTGCCCCCCTGGGCACTCCAGGAAGCTTTCAGCTTCCGTGCAACAGCCATGCGACTGGTGGAGGAGGAGCGTCGGCTGGAGGAGCCACCCCCTCCCGGCACAACGTGTCCGTGACGAACATTAAGTGCGAGCTGGACGAGCCACCCACGCCCAACGGCAACCTAGTGCCGGTAATAGCCAACTACGAACTCCACTCGGGCAGCTTACTTATTCCGCTGACCGGACAACAGAgccaggaggaggagtccGACTCCGAGGCGGAACTGACGAACATTGAGAACTTGAAGGTGCGGCGACGGGCCTCGGACAAGAACGGTCCGCGGCCCATGTCCTGGGAGGGGGAGCTGAGCGAGCCGGAGGGCGACGGCGGGGAGGAGCCCATGGAAACCGAGCCGACGATCAAAAGGGAGATCATAGCGTCTCATGCTGCCACGACCCTCCAGCCGATCAAAACCGAGCTGGAGAACATTGACGGGGAACttcaacaccagcaacagggAAGGCCATACACGCTGTGCTCATCCACGCCGCACTCCGGGCCGAAGATGAAGCTGGCGCCGACCCAGAGCGACCCGATTAATCTCAAGTTCGAGCCACCGCTGGGGGACAACTCACCGCTCCTGGCGGCCCGCAGCAAGTCGAGTAGCGGTGGCCACCTGCCGCTGCCCGCCAATCCCAGTCCGGACTCCGCCATACATTCCGTCTACACGCACAGCTCGCCCTCCCAGTCGCCGCTGACGTCCCGACACGCTCCCTACACGCCCTCGCTCAGCCGGAACAACAGCGACGCCTCCCACAGCAGCTGCTACAGCTACAGCTCGGAGTTTAGTCCCACCCACTCGCCCATTCAGGCGCGCCATGCCCCGCCCAGTGGCGCCCTTTACGGCAATGGGAGTCTGCACCATCACAGCGTGCTGTACCGACCGCTGAAGATGGAGGCTTCCTCCACCGCCTCATCCGGCAGCCACGAGGCCCAGAACCTGAGCATGGACTCGGTCTGCAGCAGCCTGGACATGAGTAGCTCCGGCTCATCCCTTCCCGCTTCGCCGGCTGGCATTTCGCGCCAACAGCTCATCAACTCTCCGTGCCCCATTTGCGGCGACAAGATCAGTGGCTTCCATTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGATTCTTCAAGCGCACAGTGCAAAATCGGAAGAACTACGTCTGCGTGCGGGGTGGTCCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGTCCGGCCTGCCGGTTCGAGAAGTGTCTGCAAAAGGGCATGAAACTGGAAGCCATTCGGGAGGACAGGACGCGTGGCGGTCGGTCCACCTATCAGTGCTCCTACACGTTACCCAATTCGATGCTCAGCCCGCTGGTGAGTCCGGACCAGGCGACAGGATCTGCAACGGTGACCagtcaacagcagcagccaaatcAGCAACAGAGACTTCATCAACTAAACGGATTTGGGGGCACATCGCTGTCCACCTCGGTTTCCCTGCCCGCCAGCCCCAATCTGGGGGCCTCCATCAAGGTGGAGGAACCGGTTGAGACAAAGCAGCAGATCCAGCGAGTAGGAAGCATTCCGCCACTTCTGAAGgaaattaTGGATGTTGAACATCTATGGCAGTACACCGACGCAGAACTGGCCCGCATCAATCAACCGCTGTCTGCATTCGCCTCCGGAAGCTCCTCGGCGACACCATCGTCCGCAGCTTCCTCAGCCGTCCACGGACAACCGCCACAGCAACCACAAGTGACCAATCCACTGCTGGCCAGTGCCGGTCTATCATCCAACGGCGAGAACGCCAACCCCGATCTGATCGCCCATCTGTGCAACGTTGCCGACCACCGTCTATATAAGATTGTGAAATGGTGCAAGAGTCTGCCCCTCTTCAAGAATATTTCGatcGATGATCAGATCTGCTTGCTAATCAATTCCTGGTGCGAGCTATTGCTCTTCTCCTGCTGTTTTCGATCCATCGACACGCCGGGCGAGATAAAAATGTCACAAGGAAGAAAGATAACCCTGTCGCAGGCCAAATCAAATGGTTTGCagACCTGCATTGAAAGAATGCTTAATCTGACAGATCATCTGAGACGTTTGCGGGTCGATCGCTATGAATACGTTGCCATGAAGGTGATTGTGCTGCTGCAGTCAGACACTACGGAGTTACAGGAGGCTGTCAAGGTGCGCGAGTGCCAGGAGAAGGCCTTGCAGAGCTTACAGGCCTATACCCTGGCTCACTATCCCGAAACTCCTTCGAAGTTTGGAGAACTCCTGCTCCGTATTCCCGACCTGCAGCGTACATGCCAGcTTGGAAAGGAGATGCTAACGATCAAGACGCGCGATGGGGCCGACTTCAACTTGCTGATGGAGCTTTTACGCGGAGAACATTGA
Protein Sequence: MPNMSSIKAEQQSAPLGTPGSFQLPCNSHATGGGGASAGGATPSRHNVSVTNIKCELDEPPTPNGNLVPVIANYELHSGSLLIPLTGQQSQEEESDSEAELTNIENLKVRRRASDKNGPRPMSWEGELSEPEGDGGEEPMETEPTIKREIIASHAATTLQPIKTELENIDGELQHQQQGRPYTLCSSTPHSGPKMKLAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPSGALYGNGSLHHHSVLYRPLKMEASSTASSGSHEAQNLSMDSVCSSLDMSSSGSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLVSPDQATGSATVTSQQQQPNQQQRLHQLNGFGGTSLSTSVSLPASPNLGASIKVEEPVETKQQIQRVGSIPPLLKEIMDVEHLWQYTDAELARINQPLSAFASGSSSATPSSAASSAVHGQPPQQPQVTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPETPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00483029;
90% Identity: iTF_00477364;
80% Identity: iTF_00481585;