Basic Information

Insect: Drosophila affinis
Gene Symbol: -
Assembly: GCA_037356375.1
Location: JAZHFB010000003.1:31265642-31271444[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.011 0.94 10.4 0.3 1 23 1303 1326 1303 1326 0.95

2 13 8 6.7e+02 1.4 0.2 1 23 1487 1509 1487 1509 0.91

3 13 0.00018 0.015 16.0 2.7 2 23 1512 1533 1512 1533 0.97

4 13 6.9e-05 0.0057 17.3 0.2 3 23 1541 1561 1539 1561 0.98

5 13 5.7e-07 4.8e-05 23.9 4.1 2 23 1568 1589 1567 1589 0.97

6 13 5.4 4.5e+02 1.9 0.4 5 23 1602 1620 1600 1620 0.96

7 13 1.4 1.1e+02 3.8 5.4 3 23 1627 1648 1625 1648 0.93

8 13 0.14 12 6.9 0.2 2 23 1659 1679 1658 1679 0.96

9 13 5.5e-05 0.0046 17.7 0.4 1 19 1685 1703 1685 1707 0.95

10 13 3.5e-05 0.0029 18.3 0.4 1 23 1715 1737 1715 1737 0.98

11 13 0.0001 0.0086 16.8 7.6 1 23 1743 1765 1743 1766 0.96

12 13 0.00022 0.018 15.8 6.5 1 23 1771 1793 1771 1793 0.98

13 13 0.0027 0.22 12.4 6.1 1 23 1799 1821 1799 1822 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.011	0.94	10.4	0.3	1	23	1303	1326	1303	1326	0.95
2	13	8	6.7e+02	1.4	0.2	1	23	1487	1509	1487	1509	0.91
3	13	0.00018	0.015	16.0	2.7	2	23	1512	1533	1512	1533	0.97
4	13	6.9e-05	0.0057	17.3	0.2	3	23	1541	1561	1539	1561	0.98
5	13	5.7e-07	4.8e-05	23.9	4.1	2	23	1568	1589	1567	1589	0.97
6	13	5.4	4.5e+02	1.9	0.4	5	23	1602	1620	1600	1620	0.96
7	13	1.4	1.1e+02	3.8	5.4	3	23	1627	1648	1625	1648	0.93
8	13	0.14	12	6.9	0.2	2	23	1659	1679	1658	1679	0.96
9	13	5.5e-05	0.0046	17.7	0.4	1	19	1685	1703	1685	1707	0.95
10	13	3.5e-05	0.0029	18.3	0.4	1	23	1715	1737	1715	1737	0.98
11	13	0.0001	0.0086	16.8	7.6	1	23	1743	1765	1743	1766	0.96
12	13	0.00022	0.018	15.8	6.5	1	23	1771	1793	1771	1793	0.98
13	13	0.0027	0.22	12.4	6.1	1	23	1799	1821	1799	1822	0.96

Sequence Information

Coding Sequence: ATGGTCGACAGCGTGCAGTGCCCCGTGTGCACCTTGTACCTGCATGCGGGTATGAATCTCTCCGACCATCTGGAGACGCATCCGAAGGAGCAGGTCATCAAGGCGCTGGTGCAGATGACAATTGTGGGCAACACTGGCATGGGTAATGCCCTGGCGGCGGCCATGCTGGGCGATGGCTcatcaggagcagcagcaggaggtgcAGAGGCCGGTGGCTCCGACGACACCACCGCCGGTGCCGCCCCGATATCGTCTCAATCTGTGGCTGATGTCAAACCAGTTGTTGTGTCCGCCAGCTCATCGGTAGCCAACAACAAACCCATAACAACTGCCTCTAATGCATCCCAAGCGtccctgccgccgccgccactctcctcctccccctcctcttcCGTTGTTGCTGTCAcagcgagcagcagcagcagcaaattgaGCAATCCACCGATGAAAGCACTGAAATGCGCACCGCCCACGACTGAGGCGCGAGCCAACAACACATCCGCACCCACCACAAACAGCGCAATAACCGCACTGTACCAGCCACCGCTGGTCACCACGGAATATCGCTATActaatcagcagcagcagcagccgcagcaacaacagcagacgAGCTTTGCGCGTGGTGCCAccacagccaccgccaccaccacttTGGTGATACCGCAGGTGCCACAGCAGCACTTCCTCGCCAGcagccatcagcagcagcagcaacagacccACTTTGCccatcagcaacagcatcctGGCCTGAAGTTTACCTATGCCACCACGCTGCCACCCCCTCCGCCGTTGCAGCTCttcacgcagcagcagcagacagcagcgcAACCGCACCAGAAACCTCCTCCCGCCTATGGAGCCGCCATCAGTCAAATACGATCTCAGCACAACCAAAAcaagcagcaacatcagcaccagcaacagcatgTGACCGTTCATCATAACGTAACCCTGGCACCACCGACgaccccaacagcagcagctggaggaaAACACAGCGGCAAAGCACACACGGAAGTATTCCTGAATCCCccaccaccgccgctgccaccGCAGGCGCAtgcccagcaccagcagcagaaccagcatcatcatcaccattcgcaacaccagcagcagcagcagacacagcAGTCTTCGATGCCCGTGGCCCTTACAACTTCGGTCAgcagacagcaacagcagacgGTGACATTGCAGACCTATGGATCGAGTGCAGGAAGTTGTTCCTCTTCCTCCTTGCCCATCTCAACGGCTGGTCGATCGAGCCGTCAGACCAACTCTCCCTTCGGTGCATTGCTCaatgctgcggcggctgctgccagCTCCTCGCCATCGTCCGCATCCGCCGCCTCGGTGCTGCGCTACGCGGAGTCGCCGGTGGCGCATTATCTGGAGCGGGAGAACGGGGACTTCATTGTCCAGGAGACACCCAAACACATTGTGGAGTGCGTTGAAAAGGAGGACGGCGAGTTCTCCGTGATCGAGCGCATTTACCAGTCGCCTCCGAGTGTTCTCCACATACacgacgaagacgaggacgacgacgatgacgatgaagaggaggaggaaaacgAAGCGGCACCGCAGGACGAGCACGACCATGTGGAGGATGGGGACGATGAGCGCGACGAGAACAGCCGCTGCCGCAACTTGACCAAAACAACGAAGAAGTCGCGCAAGACAAAGCCCAAGCGGACCTCAAAGAAAAGCCCCCGGCAACATGTCTCAGACGAGGAGTTCATGAGCATCAGCAGCGGCTGCGAGAGCGACTCTGAGCCCGAGACGAAGATGGAGGTCCAGGCTGTGGCGCCGCCACCTCTGTGCACAGCCCCATCCACGAGTAGTGCCGCGGCGGCCGCCGTAGTCGCCTCCACGTCCACCCTAGCAGATGGCCATTCGAACTCCACTTCGAACTCCAATTCCAACTCTAATGCCAAGTCCAAGAAGAACCGCATCACAGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTACCTTGATCTGATGGGCAACATCGTGGCCTCCAGTCGCATCGGCACCTCACGGCCCTTTGCAGCCGTGGCGCCCATACCCCTGGTCAAGGTAGAAAAGGAGGAGCCCATGGATGAGTACGACAATGCGGCGCAATCGGATGAGACGGATCCCATGCTCCTGGTGGAGCATAAGCCTAGCTTGGAGCAGGGTTGTGCGGGGGGACATGGCACCACCAGCGTCATCCGCATGGCCAGCGGCATGTCGGCGGCTACGGAGGACTTCACCCAGCCGCCACCCATGAAGGTGGAGGTCGAGCCGACGACGCTGCTACCTCAGCGGTTCTCGACTCCTGCTCAGCTTCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCAcggcaacgacgacgacgacaaccacaaaacaaaagactgACACCCCATCTTCCTCGAGCGCGGATCCGCTGCTGCCCTCAACATCAACCTGCACCTCCTTATCCATATCAAAATCCGCCACGGAGCTGGTCCACATCAAGAGTGAGATCACGGAGATGCCGTCAAGCAGCATACTCGAGAAGCATCTGACGACGCGGAAGCACTCGACGGTCAACGATGACGATGCTCGAGTCCTCCTTGAGTTTGCCAATTCAAAGCAGCCGGCTACCCTCGCAGGCACCGCCTCCAGCACCACCTTTGTGGTGAATGCCAATTCGGGTTTCCCGTCAGCGGGCTCCGTGTTTGCCAGCAGCACAGCGCATAGCAGTACGGTGGGGCAGAAGGCGGGCCAAGCCAAGCCGGGCGAGGAGTACATTCTGCCGGACAACAATCTGGAGGTGGACGAAATTGTGATATCCTCCTCGTCTTCCTACGCCTCATCCGTGGCGCAGGTGCATCCATCGCTGCCCTTATCGCTGCAGCCGCCCGCAGCGGCCGCATCCTTCAACGACTTCAATTTCCTATACCAGCAGACCACGAGCACAGCCACGACGTCCGCGAACTGCGCCTACTTCACGCCCTTCGGCagacaacaaaagcagcagcagcaacagacgcAGCACGGAGTCAGCGATGCCACCAATGCAGCCACCTTGGCCTCCTCTTCCAGCAATTCCTCGGCAATGGATCACGACTCGATGAATGCCACCTTTCGACTGGCGAAGACGCAAGCGCTTCAGTCCTGGTACCAGCCAGATCAAGACCAGGATCCACAGCATCAgtcagcagcaggcgcagcagctgcagcatcgGGAGCCTCCTCCTctagccagaaccagaaccatgAAGGGGCCCAGCCCACCAACTTCAATGCCGCTTTGGCTGCCGTCGATTGCTGCAGTGTGGCCGTCGATGGCGATGTCAAGTATCTGGATCTGGACGCGTGCAAGCGGGAGCagctgagcagcagcagcaatctgCCATCGGCATCCGCCTCCACATCGACAACTTCCTCATCGTTCGCTGGGGCGGCAACGGAGAGCAGTCTTGTCGGCGGGCTCAACATACGCACCGATGAGAAAATGCCCGCCAAGGGTGAAATCTCAGAGCAGGAGAGCAACTGCGACATCGAGAACTCGTGGAGTCAGTCGGTGTACGGCGACATATCACAGCGATACTTTAGGAATCAGTTCACTGGCGGCTATAACCCCGACTGGAGGCAAGACTACTATCCTGTGCAGGATCTCAGCGCTCAGCAGCGGGAGCATAAGCGATTCGATTTTAATACTGTCGACGATGAAGCCTCATCCAGCTCCAGAAAGAGTCATCTGATTGACGAGCAGCCGGCAGCCACCACTTCCTCTGCGTCATCGGCATTGCTGGCTGGTCCACCAATCGCTTCAACGTCCAGGGCTGCCGCTGAGGCGGCGGAGGCAGCGGCGGCTTCGGCTGCTTTGGCGCAGCGCAAGCCGCAGCGTCGCAAGCTCTACAAGTGTCCGCATTGCGAGGCCATCTTCGAAAAGCTCAAGGAGCGGAATGCGCACATGATTGGCGAGCACAACTATGTGCGTCAAAATCGACGTCTGATTTGCACGCAGCCGCAGATTAGCGGCCCGATGTTACCCCCACCTCCGtctcagcagcaacagcaccagcagctgctTATGCATGCGGGCGTCGGCCTGGGCAACGGTGGCGGCGAAGCTATGCAAGAGGATTCCAAAGATGGCATTGTCAAAATCAAGCAGGAACAGTGCCAGGAAAGGACGGATGTGGAACAGATAGAGACCAGCCCTGAGCTACTGACCGATGTCAAAGATTCCGAGCTGTTAGGCATTGGCGATGGCGAAGCGGATGGTGATATCAAGCCGCCCAGCCAGCTAGACCATAAAATGACCCTCCCGCCATTGGCGATGACCACGCCAGCCGCCAAATTGGCGGCCTTATATCGAATGCTTATTTCCTACAACGAGTCCAAGCTGGGACAGGAGCGTAACAACCTCAACGAGCTGGAGCAGAAGGCGATGGAGAAGTCCATCTTTCTGTGCTATGTCTGCCGCACCGACTTCCCCTCCGTTAAGCTCTACGATGCGCATCTCACGGAGCATCCCGCCGAGTGCTTCACCTGTGGCAAGAAATTCTATAGGTGGAAGAACTTTTCCCTGCATCTGAAGCGCCACTTGGGCTGGAAGGAGTTTGGCTGCTATGTCTGCGACAAGAAGTTTGTCGTGCGCAGCGCCCTCGTGGAACACATGCGCATGCACACGGGCCAGACACCGCTCAAATGCAAGATATGCGGCAAAAAGTTTAAGCGGTACTCAAATCTGACGCAGCATCGCAAGCGGCACACAAAGGTGATGGTGCGCAAGAAGGAATATGTGTGCCACTGCGGCGAGGTGTTGCCGTCGAAGGCACGCTTTCTCTGGCACAAGGAGACGCACGATGTGAAGCCCAAGTGCTGCCCGTACTGCTGCGATCGATTCGTGCATGCCAACTCGCTGCGCCGCCACATACGGCTGGCGCACTCAGATAAGTTCGACTACGCCGAGCCGATGGAGTGCCCCATGTGCAAGCAGATCTTTGCCAAGACCTCGATCAAGGCGCATATGGCCACACACTCGACTGATCCGCAGTACGACTGCGCCATCTGCAATAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCACGCCAATCGGACGGCGAAACCGTTTAAGTGCGAGTACTGCCCAAAAGCGTTTGTGCGAGAGCTGGACTTCAAGAATCACATCAACGCACACAAGCAGATCAAGCCGTACACCTGCGAGTATTGTGGCTGCAAGTTCATACGAAAGTACAACTACATGCGGCATCGTCGTGAGCACCACGGCACCAAGAAGTTCACCTGTGACCAGTGCGACAAGTCATTCCATCGGCACTACTATCTGATCGAGCACCGGCGCATGCACACGGGCGAGCGACCTTTCACTTGCACCATATGCGGCAAGAGCTCCACCACTAAGACCAATCACAACAAACATCTGAAAATCCATCACTCGCGGGATCCCTTCACCGTGGAGGTCTAA
Protein Sequence: MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNTGMGNALAAAMLGDGSSGAAAGGAEAGGSDDTTAGAAPISSQSVADVKPVVVSASSSVANNKPITTASNASQASLPPPPLSSSPSSSVVAVTASSSSSKLSNPPMKALKCAPPTTEARANNTSAPTTNSAITALYQPPLVTTEYRYTNQQQQQPQQQQQTSFARGATTATATTTLVIPQVPQQHFLASSHQQQQQQTHFAHQQQHPGLKFTYATTLPPPPPLQLFTQQQQTAAQPHQKPPPAYGAAISQIRSQHNQNKQQHQHQQQHVTVHHNVTLAPPTTPTAAAGGKHSGKAHTEVFLNPPPPPLPPQAHAQHQQQNQHHHHHSQHQQQQQTQQSSMPVALTTSVSRQQQQTVTLQTYGSSAGSCSSSSLPISTAGRSSRQTNSPFGALLNAAAAAASSSPSSASAASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDEDEDDDDDDEEEEENEAAPQDEHDHVEDGDDERDENSRCRNLTKTTKKSRKTKPKRTSKKSPRQHVSDEEFMSISSGCESDSEPETKMEVQAVAPPPLCTAPSTSSAAAAAVVASTSTLADGHSNSTSNSNSNSNAKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGTSRPFAAVAPIPLVKVEKEEPMDEYDNAAQSDETDPMLLVEHKPSLEQGCAGGHGTTSVIRMASGMSAATEDFTQPPPMKVEVEPTTLLPQRFSTPAQLRGPKKLVIKPKATATTTTTTTKQKTDTPSSSSADPLLPSTSTCTSLSISKSATELVHIKSEITEMPSSSILEKHLTTRKHSTVNDDDARVLLEFANSKQPATLAGTASSTTFVVNANSGFPSAGSVFASSTAHSSTVGQKAGQAKPGEEYILPDNNLEVDEIVISSSSSYASSVAQVHPSLPLSLQPPAAAASFNDFNFLYQQTTSTATTSANCAYFTPFGRQQKQQQQQTQHGVSDATNAATLASSSSNSSAMDHDSMNATFRLAKTQALQSWYQPDQDQDPQHQSAAGAAAAASGASSSSQNQNHEGAQPTNFNAALAAVDCCSVAVDGDVKYLDLDACKREQLSSSSNLPSASASTSTTSSSFAGAATESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSQSVYGDISQRYFRNQFTGGYNPDWRQDYYPVQDLSAQQREHKRFDFNTVDDEASSSSRKSHLIDEQPAATTSSASSALLAGPPIASTSRAAAEAAEAAAASAALAQRKPQRRKLYKCPHCEAIFEKLKERNAHMIGEHNYVRQNRRLICTQPQISGPMLPPPPSQQQQHQQLLMHAGVGLGNGGGEAMQEDSKDGIVKIKQEQCQERTDVEQIETSPELLTDVKDSELLGIGDGEADGDIKPPSQLDHKMTLPPLAMTTPAAKLAALYRMLISYNESKLGQERNNLNELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKVMVRKKEYVCHCGEVLPSKARFLWHKETHDVKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487461; iTF_00601227; iTF_00484655; iTF_00517906; iTF_00473973; iTF_00603547; iTF_00474670; iTF_00611516; iTF_00515068; iTF_00580957; iTF_00536225; iTF_00575028; iTF_00481022;
90% Identity: iTF_00487461;
80% Identity: -