Basic Information

Insect: Drosophila ambigua
Gene Symbol: -
Assembly: GCA_018150905.1
Location: JAECWS010000086.1:5722548-5728667[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0087 0.59 10.5 0.3 1 23 1186 1209 1186 1209 0.95

2 13 6.2 4.2e+02 1.5 0.2 1 23 1376 1398 1376 1398 0.91

3 13 0.00014 0.0094 16.1 2.7 2 23 1401 1422 1401 1422 0.97

4 13 5.4e-05 0.0036 17.4 0.2 3 23 1430 1450 1428 1450 0.98

5 13 4.5e-07 3e-05 24.0 4.1 2 23 1457 1478 1456 1478 0.97

6 13 4.2 2.9e+02 2.0 0.4 5 23 1491 1509 1489 1509 0.96

7 13 1 71 3.9 5.4 3 23 1516 1537 1514 1537 0.93

8 13 0.11 7.5 7.0 0.2 2 23 1548 1568 1547 1568 0.96

9 13 4.3e-05 0.0029 17.8 0.4 1 19 1574 1592 1574 1596 0.95

10 13 2.7e-05 0.0018 18.4 0.4 1 23 1604 1626 1604 1626 0.98

11 13 8e-05 0.0054 16.9 7.6 1 23 1632 1654 1632 1655 0.96

12 13 0.00017 0.011 15.9 6.5 1 23 1660 1682 1660 1682 0.98

13 13 0.0021 0.14 12.4 6.1 1 23 1688 1710 1688 1711 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0087	0.59	10.5	0.3	1	23	1186	1209	1186	1209	0.95
2	13	6.2	4.2e+02	1.5	0.2	1	23	1376	1398	1376	1398	0.91
3	13	0.00014	0.0094	16.1	2.7	2	23	1401	1422	1401	1422	0.97
4	13	5.4e-05	0.0036	17.4	0.2	3	23	1430	1450	1428	1450	0.98
5	13	4.5e-07	3e-05	24.0	4.1	2	23	1457	1478	1456	1478	0.97
6	13	4.2	2.9e+02	2.0	0.4	5	23	1491	1509	1489	1509	0.96
7	13	1	71	3.9	5.4	3	23	1516	1537	1514	1537	0.93
8	13	0.11	7.5	7.0	0.2	2	23	1548	1568	1547	1568	0.96
9	13	4.3e-05	0.0029	17.8	0.4	1	19	1574	1592	1574	1596	0.95
10	13	2.7e-05	0.0018	18.4	0.4	1	23	1604	1626	1604	1626	0.98
11	13	8e-05	0.0054	16.9	7.6	1	23	1632	1654	1632	1655	0.96
12	13	0.00017	0.011	15.9	6.5	1	23	1660	1682	1660	1682	0.98
13	13	0.0021	0.14	12.4	6.1	1	23	1688	1710	1688	1711	0.96

Sequence Information

Coding Sequence: ATGGTCGACAGCGTGCAGTGCCCCGTGTGCACCTTGTACCTGCATGCGGGTATGAATCTCTCCGACCACCTGGAGACTCATCCGAAGGAGCAGGTCATCAAGGCGCTGGTGCAGATGACAATTGTGGGCAACACTGGCATGGGCAATGCCCTGGCGGCGGCCATGCTGGGCAATGGCTCATCAGCAGCAACAGGAGGTGCAGTTGCCGGTGGGGCCGAAGACACCGCCGCTGCCGCCGCCGCCTCCTCGGCTTCGTCGCCATCTGTGGCTGATGTCAAACCAGTTGTTGTGGCCGCCAGCTCATCGGTAGCCAAACCCATAACATCAGCCTCGAATGCATCCACGGCGTCCCTGCAGCCGCCGCCACTCTCCTCCTCCTCCTCAGCGAGCAATAGCTGTAGCAGCAGCAGCAGCAAATTGAGCAATCCACCGATGAAAGCACTGAAATGCGCACCGCCCACGACTGAGGCGCGAGCCAACAACACATCCAACAACGCACCCACCACAAACAGCGCAATGACCGCCCTGTACCAGCCACAGCTGGTCACCACGGACTATCGCTACACTAATCAGCAGCAGACGAGCTTCGCGCGTGGTACCAGCACCGCCACAGCGACCGCCACCCTGGTGATACCACAGGTGCCCCAGCAGCACTTCCTCGCCAGCAGCCATCCCCAGCAGCAGCAAACCCACTTTACCCATCAGCAGCAGCAGCAGCATCCTGGCCTGAAGTTTACCTATGCCACGACGCTGCCGCCCCCTCCGCCGCTGCAGCTCTTCACGCAGCAGCAACAACAGCAGCAGCAGCAGACAGTAACGCAACCGCACCAGAAACCTCCTCCCGCCTATGGAGCCGCCATCAGCAGCTGCTCCACTTCCTCATCGACAACTGGTCGTGGGAGCCGTCAGACCAACTCTCCCTTTGGCGCATTGCTCAATGCTGCGGCGGCTGCTGCCAGTTCCTCGCCCTCGTCCGCGTCTGCATCTTCCGCCTCGGTGCTGCGTTATGCAGAGTCGCCAGTGGCGCATTATCTGGAGCGGGATAACGGGGACTTTATTGTCCAGGAGACGCCCAAGCATATTGTGGAGTGCGTTGAAAAGGAGGACGGCGAGTTCTCCGTGATCGAGCGCATTTACCAGTCGCCTCCGAGTGTTCTTCACATACACGACGACGACGAGGACGACGAAGACGACGAGGATGATGATGAGGATGAGGAGAACGAGGCGGCACCGCTGGACGAGCACGATCATGTGGAGGATGGGGACGATGAGCGGGACGAGAACAGCCGCTGCCGCAACTTGACGAAAACAACGAAAAAGTCGCGCAGGACAAAGCCCAAGCGAACCTCCAAGAAAACCCCGCGGCAACATCTGTCGGACGAGGAGTTCATGAGCATCAGTAGCGGGTGCGAGAGCGACTCGGAGCCGGAGACGAAGATGGAGGTGCAGGCGGTGGCACCGCCTCCTCTGTGCACGGCCCCATCTACGAGCAGTGCAGCGGCGGCGGCCGCCGCAGTCGCCACCGCGTCCACCCTGGCCGATGGCCATTCGAACTCCACCTCGAACTCCAATTCGAACTCGAATGCCAAGTCCAAGAAGAACCGCATCACAGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTACCTCGATCTGATGGGCAACATTGTGGCCTCCAGTCGCATCGGCACCTCTCGGCCATTTGCCGCCGTGGCGCCCATTCCGCTGGTCAAGGTGGAGAAGGAGGAGCCCCTCGATGAGTACGACAATGCGGAGGGGCATATGTCGGATGCGACGGATCCCATGCTGCTGCTGGAGCACAAGCCCAGCTTGGAGCAGAGCTGTGGCACAACCAGCGTCATCCGCATGGCCAGCGCCATGTCGGCGGCCACGGAGGACTTCACCCAGCCGCCGCCCATGAAGGTCGAGGTCGAGGCCACGACGCTGCTACCTCAGCGGTTCTCGACTCCTGCACAGCTTCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCACGGCAACGGCAACGACGACGACGACGACAACAACAACAAAACAAAAGACTGACACCCCATCTTCCTCGAGCGCGGATCCTCCAGCATCCAACAGCACCTCCTCCTCATCCATATCAAAATCCGCCACGGAGCTGGTCCACATTAAGAGCGAGATCACGGAGATGCCGTCGAGCAGCATCCTGGAGAAGCATCTGACCACGCGGAAGCACTCGACGGTCAACGATGACGATGCTCGGGTGCTGCTGGAGTTCGCCAATTCGAAGCAGCCGTCGACACTCGCCGGCACCGCCTCCAGCACCACCTTTGTGGTGAATGCCAATTCTGGTTTCCCCTCCGCGGGCTCTGTGTTTGCCAGCAGCACGGGCACGGGGGCGCCGAAGACGGGCCCAGCCAAGCCGGGCGAGGAGTACATTCTGCCGGACAACAATCTGGAGGTGGACGAAATTGTGATATCCTCCTCGTCTTCCTACGCCTCATCCGTGGCGCAGGTGCATCCATCGCTGCCCGCATCGCTGCAGCCACCAGCAGCTGCCGCTTCCTTTAACGACTTCAATTTCCTGTACCACCAGACCACAAGCACGGCCACAACGTCCGCGAACTGTGCCTACTTCACGCCCTTTGGCCGCCAGCAACAGCAGCAGCAGCAGCAACATACGCAGCACGGAGTCAGCGATGCCACAAATGCAGCCACCTTGGCCTCCTCTTCCAGCAATTCCTCGGCGATGGATCACGACTCGATGAATGCCACGTTTCGGGTGGCCAAGACGCAGTCGCTGCAGTCCTGGTACCAGCCAGATCAAGATCACGATCCACAGCATCAGTCAGCAGCTGCAGCATCAGCAGCCGGAGCAGGAGCGGGAGCGGGAGCGTCCTCCTCTAGCCAGAACCAGAACCATGAAGGGGCGCAGCCCACCAACTTCAATGCCGCATTGGCTGCAGTCGATTGCTGCAGTGTGGCCGTCGATGGGGATGTCAAGTATCTGGATTTGGACGCGTGCAAGCGGGAGCAGCTGAGCAGCAGCAGCAATCTGCCATCAGCATCCGCCTCCACATCGACCACATCTTCATCGTTCGCTGGCGCGGCCACAGAGAGCAGCCTTGTGGGCGGGCTCAACATACGCACCGATGAGAAAATGCCCGCCAAGGGCGAAATCTCAGAGCAGGAGAGCAACTGTGACATCGAGAACTCGTGGAGTCAGTCGGTGTACGGCGACATATCACAGCGATACTTTAGGAATCAGTTCACTGGCGGCTACAACCCCGACTGGCGGCAGGACTACTATCCGGTGCAGGATCTCAGCGCTCAGCAGCGGGAGCACAAGCGATTCGATTTTAATGCTGTCGACGACGAGGCCTCCTCGAGCTCCAGAAAGAGTCATCTGATTGATGATCAGCCGGCAGCGACCACTTCCTCGACGTCTTCGGCATTGCTGGCTGGTCCACCAATCGCTTCAACGTCCAGGGCTGCCGCTGAGGCGGCGGAGGCAGCAGCAGCTTCGGCTGCGTTGGCGCAGCGCAAGCCGCATCGTCGCAAGCTCTACAAGTGTCCGCACTGCGAGGCCATCTTCGAGAAGCTGAAGGAGCGGAACGCGCACATGATTGGCGAGCACAACTATGTGCGTCAGAATCGGCGTCTGATTTGCACACAGCCGCAAATCGGTGATGCATCGATGTTGCCCCCACCACCGTCTCAGCAGCAACAGCAGCAGCAGCTGCTCATGCATGCGGGCGTGGGTGTTGGCATGGGCAACGGTAGCGATGAAGGTGTACAAGAGGATTCCAAAGATGGCATTGTCAAGATCAAGCAGGAACAGTGCCAGGACAGGCCGGATGTGGAGCAGATTGAGACCAGTCCCGAGCTATTGACCGATGTCAAAGATTCCCAGCTGCTGGGCATTGGCGGTGGTGGCGATGGCGAAGCGGATGGTGATATCAAGCCGCCCAGTCAGCTGGACCAAAAAATGACACTCCCGCCATTGGCAATGACCACGCCAGCCGCCAAATTGGCGGCTTTATATCGAATGCTTATTTCCTACAACGAGTCGAAGCTGGGACAGGAGCGCAACAACCTCAACGAGCTGGAGCAGAAGGCGATGGAGAAGTCCATCTTTCTGTGCTATGTCTGCCGCACCGACTTTCCCTCCGTTAAGCTCTACGATGCACATCTCACGGAGCATCCCGCCGAGTGCTTCACCTGTGGCAAGAAATTCTACAGGTGGAAGAACTTCTCCCTGCATCTGAAGCGCCACTTGGGCTGGAAGGAGTTCGGCTGCTATGTCTGTGACAAGAAGTTTGTCGTGCGGAGCGCCCTCGTCGAGCACATGCGCATGCACACGGGCCAGACGCCGCTCAAATGCAAGATATGCGGCAAAAAGTTTAAGCGGTATTCGAATTTGACGCAGCATCGCAAACGGCACACAAAGGTGATGGTGCGCAAGAAGGAGTACGTTTGCCACTGCGGCGAGGTGCTGCCGTCGAAGGCACGCTTTCTGTGGCACAAGGAGACGCACGATGTGAAGCCCAAGTGCTGCCCGTACTGCTGCGACCGGTTCGTGCATGCTAACTCGCTGCGCCGGCACATACGGCTGGCGCACTCGGATAAGTTTGACTACGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACCTCGATCAAGGCGCATATGGCCACGCACTCGACGGATCCGCAGTACGACTGTGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACACTCGTGGGTGCACGCCAATCGGACGGCGAAACCGTTCAAATGCGAGTACTGCCCAAAGGCGTTTGTGCGAGAGCTGGACTTCAAGAACCACATCAACGCACACAAACAGATCAAGCCGTACACCTGCGAGTACTGCGGCTGCAAGTTCATACGAAAGTACAACTACATGCGGCACCGACGCGAACACCACGGCACCAAGAAGTTCACCTGCGACCAGTGCGACAAGTCATTCCATCGGCACTACTATCTGATCGAGCACCGTCGCATGCACACGGGCGAGCGGCCATTCACCTGCACCATATGCGGCAAGAGCTCCACCACCAAGACCAATCACAACAAGCATCTGAAAATCCATCACTCGCGCGATCCCTTCACCGTGGAGGTCTAA
Protein Sequence: MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNTGMGNALAAAMLGNGSSAATGGAVAGGAEDTAAAAAASSASSPSVADVKPVVVAASSSVAKPITSASNASTASLQPPPLSSSSSASNSCSSSSSKLSNPPMKALKCAPPTTEARANNTSNNAPTTNSAMTALYQPQLVTTDYRYTNQQQTSFARGTSTATATATLVIPQVPQQHFLASSHPQQQQTHFTHQQQQQHPGLKFTYATTLPPPPPLQLFTQQQQQQQQQTVTQPHQKPPPAYGAAISSCSTSSSTTGRGSRQTNSPFGALLNAAAAAASSSPSSASASSASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEDDEDDDEDEENEAAPLDEHDHVEDGDDERDENSRCRNLTKTTKKSRRTKPKRTSKKTPRQHLSDEEFMSISSGCESDSEPETKMEVQAVAPPPLCTAPSTSSAAAAAAAVATASTLADGHSNSTSNSNSNSNAKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGTSRPFAAVAPIPLVKVEKEEPLDEYDNAEGHMSDATDPMLLLEHKPSLEQSCGTTSVIRMASAMSAATEDFTQPPPMKVEVEATTLLPQRFSTPAQLRGPKKLVIKPKATATATTTTTTTTTKQKTDTPSSSSADPPASNSTSSSSISKSATELVHIKSEITEMPSSSILEKHLTTRKHSTVNDDDARVLLEFANSKQPSTLAGTASSTTFVVNANSGFPSAGSVFASSTGTGAPKTGPAKPGEEYILPDNNLEVDEIVISSSSSYASSVAQVHPSLPASLQPPAAAASFNDFNFLYHQTTSTATTSANCAYFTPFGRQQQQQQQQHTQHGVSDATNAATLASSSSNSSAMDHDSMNATFRVAKTQSLQSWYQPDQDHDPQHQSAAAASAAGAGAGAGASSSSQNQNHEGAQPTNFNAALAAVDCCSVAVDGDVKYLDLDACKREQLSSSSNLPSASASTSTTSSSFAGAATESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSQSVYGDISQRYFRNQFTGGYNPDWRQDYYPVQDLSAQQREHKRFDFNAVDDEASSSSRKSHLIDDQPAATTSSTSSALLAGPPIASTSRAAAEAAEAAAASAALAQRKPHRRKLYKCPHCEAIFEKLKERNAHMIGEHNYVRQNRRLICTQPQIGDASMLPPPPSQQQQQQQLLMHAGVGVGMGNGSDEGVQEDSKDGIVKIKQEQCQDRPDVEQIETSPELLTDVKDSQLLGIGGGGDGEADGDIKPPSQLDQKMTLPPLAMTTPAAKLAALYRMLISYNESKLGQERNNLNELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKVMVRKKEYVCHCGEVLPSKARFLWHKETHDVKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00471815;
90% Identity: -
80% Identity: -