Dhop036438.1
Basic Information
- Insect
- Dorcus hopei
- Gene Symbol
- -
- Assembly
- GCA_033060865.1
- Location
- CM065425.1:72731319-72732389[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00021 0.023 16.6 0.4 2 23 21 42 20 42 0.97 2 12 0.0001 0.012 17.6 2.4 3 23 49 69 47 69 0.98 3 12 3.3e-05 0.0037 19.1 3.7 1 23 75 97 75 97 0.97 4 12 0.00077 0.085 14.8 2.1 2 23 104 125 103 125 0.95 5 12 0.00055 0.061 15.3 3.8 1 23 131 153 131 153 0.98 6 12 4.6e-06 0.00051 21.8 2.5 1 23 159 181 159 181 0.99 7 12 0.00054 0.06 15.3 2.6 1 23 187 209 187 209 0.98 8 12 0.00042 0.047 15.6 5.8 1 23 215 237 215 237 0.98 9 12 0.00027 0.03 16.3 4.2 1 23 243 265 243 265 0.98 10 12 0.008 0.89 11.6 5.0 1 23 271 293 271 293 0.97 11 12 0.00017 0.019 16.9 2.9 1 23 299 321 299 321 0.98 12 12 0.001 0.11 14.4 0.3 3 23 329 349 327 349 0.98
Sequence Information
- Coding Sequence
- ATGCTGTATACGAACAGTCTATCTAGTCTAAGAAATAACGGTTGTTCCAGATGTGAACTCAGATGCGCCGTTTGCGATTCCGAATTTCAATACTCGGCGAACTTGAAGCAGCACATGTCGACGCACACGGAGAAGTCCTTCGGCTGCGACgtctgcgattacaaatgccgaaaaTCGGCGGATCTGAAGCGGCACATGTTGAAACACACCGAGGAGAAGCCGCACGTTTGCGGCCTCTGCGACTATAAGTGCCGATACGCCGAGAATTTGAAGCggcacatgttaacgcacaccgacgagaagccctTGAATTGCAcgctttgcgattacaaatgccgacagtACGGGAGTTTGAAGAAGCACATACTAgcacataccggcgagaagccctTCAGCTGCGAGGTTTGCGATTGCAAGTTCGAGGAGCACGGAAAACTAAAGCGGCACATGTcgatacacaccggcgagagaCCGTACAGTTGTGAcctctgcgattataagtgccgacaGCCCGGATATTTGCGGCGCCACATGCTGACGCACACCGACGACAAGCCGTTCAgctgtgacctttgcgattataaatgccgatacCCCGAGAGTATGAAACGGCACGTGTTAACGCACACGGgggagaagccgttcagttgtgaccacTGCGACTATAAGTGCGTACAATCGACGTATTTGAAGCAGCACCTGCTGACACACTTCGACGacaagccgttcagttgtgatctttgcgactacAAGTGCCGGAAATCGGCGTACCTTAAACAGCACATGCTGaaacataccggcgagaagccgttcagctgtgacttttgcgattataaatgtcggcaGCTCACGAGCTTGAAACAACACACGCTGCAGCACACCGGCGAAAAACCATTCACTTGcaacctttgcgattacaaatgccggcAGCCCGGAAGGTTGAAGGAACACATGCtgaagcacaccggtgagaggACCTTCGGTTGTGATAATTGCGATTTGAAATTTCGCGAGGATGGGGAGTTGAAACGGCACGTGTTAACACACACTGAAGAGAAGCCAATTATTTAA
- Protein Sequence
- MLYTNSLSSLRNNGCSRCELRCAVCDSEFQYSANLKQHMSTHTEKSFGCDVCDYKCRKSADLKRHMLKHTEEKPHVCGLCDYKCRYAENLKRHMLTHTDEKPLNCTLCDYKCRQYGSLKKHILAHTGEKPFSCEVCDCKFEEHGKLKRHMSIHTGERPYSCDLCDYKCRQPGYLRRHMLTHTDDKPFSCDLCDYKCRYPESMKRHVLTHTGEKPFSCDHCDYKCVQSTYLKQHLLTHFDDKPFSCDLCDYKCRKSAYLKQHMLKHTGEKPFSCDFCDYKCRQLTSLKQHTLQHTGEKPFTCNLCDYKCRQPGRLKEHMLKHTGERTFGCDNCDLKFREDGELKRHVLTHTEEKPII
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01258884; iTF_00467111; iTF_00467112; iTF_00465621; iTF_01258458; iTF_00466717; iTF_00466718;
- 90% Identity
- iTF_00465621;
- 80% Identity
- iTF_00465621;