Basic Information

Insect: Cheilosia variabilis
Gene Symbol: -
Assembly: GCA_951230905.1
Location: OX579677.1:57874368-57877581[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00016 0.022 16.0 1.1 2 23 393 414 392 414 0.97

2 16 1.8e-05 0.0026 18.9 1.0 1 23 420 442 420 442 0.98

3 16 0.39 55 5.3 0.0 1 17 448 464 448 465 0.93

4 16 3.4e-05 0.0048 18.1 3.5 1 23 482 504 482 504 0.98

5 16 5.1e-05 0.0072 17.5 0.2 1 23 537 559 537 559 0.97

6 16 7.3e-05 0.01 17.1 1.8 1 23 565 587 565 587 0.98

7 16 7.9e-06 0.0011 20.1 1.0 2 23 698 719 697 719 0.97

8 16 4.6e-06 0.00064 20.8 3.1 1 23 725 747 725 747 0.98

9 16 1.1e-05 0.0015 19.6 0.2 1 23 753 776 753 776 0.98

10 16 0.00018 0.025 15.8 1.2 1 23 787 809 787 809 0.98

11 16 6.7e-06 0.00095 20.3 1.4 1 23 821 843 821 843 0.98

12 16 0.016 2.3 9.6 2.0 1 23 849 871 849 871 0.97

13 16 0.00012 0.017 16.4 0.6 2 23 877 899 876 899 0.95

14 16 0.1 15 7.1 0.2 1 23 907 930 907 930 0.95

15 16 0.00065 0.091 14.1 0.5 3 23 940 961 939 961 0.93

16 16 0.0026 0.36 12.2 0.8 2 23 967 988 966 988 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00016	0.022	16.0	1.1	2	23	393	414	392	414	0.97
2	16	1.8e-05	0.0026	18.9	1.0	1	23	420	442	420	442	0.98
3	16	0.39	55	5.3	0.0	1	17	448	464	448	465	0.93
4	16	3.4e-05	0.0048	18.1	3.5	1	23	482	504	482	504	0.98
5	16	5.1e-05	0.0072	17.5	0.2	1	23	537	559	537	559	0.97
6	16	7.3e-05	0.01	17.1	1.8	1	23	565	587	565	587	0.98
7	16	7.9e-06	0.0011	20.1	1.0	2	23	698	719	697	719	0.97
8	16	4.6e-06	0.00064	20.8	3.1	1	23	725	747	725	747	0.98
9	16	1.1e-05	0.0015	19.6	0.2	1	23	753	776	753	776	0.98
10	16	0.00018	0.025	15.8	1.2	1	23	787	809	787	809	0.98
11	16	6.7e-06	0.00095	20.3	1.4	1	23	821	843	821	843	0.98
12	16	0.016	2.3	9.6	2.0	1	23	849	871	849	871	0.97
13	16	0.00012	0.017	16.4	0.6	2	23	877	899	876	899	0.95
14	16	0.1	15	7.1	0.2	1	23	907	930	907	930	0.95
15	16	0.00065	0.091	14.1	0.5	3	23	940	961	939	961	0.93
16	16	0.0026	0.36	12.2	0.8	2	23	967	988	966	988	0.96

Sequence Information

Coding Sequence: ATGTCTGTCAAGTTGGACGACACAGTGTGCCGCGTATGTTTAAGTTCCTGTGGCAACATACCAATTTTCGATGGATGCGGCAAAGATGATCAATTTCGATACTGCACTTCCTTGGAGGCGAACGTGGACGATGGATTACCGTCCAAGCTCTGCAAGAAGTGCAACGATCATTTGAAGGTTGCCTATGATTTCCGATTTCAGGCAATTTATGCCGAGAAATATTTCAGGAAGACAATATTTTTGCCTTCTTTCAAAAAAGAAGATACGGAAGGGACTGCAGACATCTCGGATGTGCGCGACTGTACCGATGAATTGGATGAGAATATGGCTGAGATTGATATGTTGCTAGCAATACACACTGAAACTGTCGATGAGGGCGACGAAGACGATGACGATATGAATAATTCTGGGTTCTACGATGATGACGAGAGTGTCGATGAGAACAGAAAGCACATTGAAATCATTGGCATGGATACGTTTGAGAAGGAGCAGCGAGAACAGAAGGATCAGAAAGTCAAAATTGAAATAGCTGCTGTCCCTCCACCGCTTGTGTCATCAACTGTGTGTACTCTGGAATATGTGCCGCCGAAACCTGTAACAGGCATACCTGCGGAATCACCACAACCTGCAACAACAAGCAGCAATACTATGCCTAATGTAGACATAAATTCCTTACAACAGTATACAACTTCAAGTCCTTTTTCGACACAATCAGTGCAAGATGTGCAGATCGATCATGGAACCGAAACATCCCTCCAATTAGAGATTATCCCAATCGTGAAGAATGATCCATCCACGTATGATTTTACCACTACTGCTACAGTTACCGACGCCTATGATGCATATAACGCTCCAACGCACATTCAGTACCAACAGCCTATGTCCATGCACCTGCAGTACGAGCAACCAAGCGCGACATTGCCATTGCAGGAATCTGTTTCTGTTGCAGACAACTATGAGTTCCCGTACCAACCACAGTTCTCTACATACACCGCCCAAACAATCGAAATTAGACCTGCGAATCAGGCAATTTCTCCAGCTCAGCAGGAGCAACAAAATCAGATCGTTTCAATTGTAAGAACTGAAACTCAACCCGAAACCACCACAAAGACTGAAAATCTGAATCCCAAACCTAAAAAGGCTAAGCGTGAAGGCCACAGTCGCAGGGACAAGATCGAATGCAACATCTGTGGAAGCATCTTCACGCATTTGAACTCGCTGAAGACGCACCTCCTTAAGCACTCTGGTGAAAAACCCTTCCGCTGTGAGTTTTGCGACAAGGCCTTTGCAAGAAAGACTGTCCTCAATATCCACCGACGTCTTCACACTGGAGAGAAACCCTATCAATGTCCGCTTTGCTCCAGCGCCTATGTGACAAAGGAAGCCTTAACTGCAAATCACGAACAGGAAGTGGGTGCCAATTTCCGCAAGGACAAGGTCTCCTACATCTGCTCCATATGCAACAAGTCGCGTTGCTCCAAATACTCTCTAGCGTCGCACATGAAGACACACTCGAGCGATGCAAAGGCCAGACGCAAGATGGTTCgacgaaaaaaggaaaaatccgGGGGCAGCAATGGCACCGCAACAACCAGCGCTCCGCACAAGTATTCGTGCAAGATCTGCCAAAAAGGTTTTCCCAACAAATGGGAACTTAGTACTCACGCCGAGTCTCATGACATGCACAAGACATTCGAGTGCGACGTCTGTCAGCGAACATTCGAAAAGAAGTTCCAGTTGCTGTACCATCTGCAGACGCACGATGGTGGCGATGAACTTGTAAAAGCGAAGGTGCAACCAGCGATTGAAAATCGAGAAAGTGCTGATAAAGTAACGGAGAAGTCGGTGCAAAAGCAACTGCCAACTGgaaaaaaaccgaaaagaaaACTCTCGGCGAGGAAGCGGCATAAAAGAAAAgcgaaaaatgcaaatgctgcCGGCGATGAAGCCGACGAACCACTTGAGGAAGAAGAAAATGACGATGAAGATGACAAGGACTTCGAGCTTGTGAAAGCAGAAAAGGACACAAAGAAGAGGACAATTCGAGCACAGCGCGAGAACCTCAAAGCACTACGAGCGGGTAGCAAAATTGAATGTCACATATGCGAGGCTGTATTTACGCATCCCACATCGCTAAAAACGCACATGTTGGTGCATTCAGGTGAGCGCCCGTTCAAGTGCGACCATTGCGATAAGTCATTTGCAAGAAAAACTGTTCTCAATATTCACCGAAGGCTGCACACCGGAGAGAAGCCCTACAAGTGTCCCCTCTGTGATAGTGCCTACGTCACAAAGGATGCTCTAATGCGCCACATGTCGAAGGACCACGACGATGACAGGGAAGCCGATCGAATTAAGTTCACGTGTGGCATCTGCCATAAGGCGATGGGCACCAAGTACTCGCTGCAAGCCCATATGAAACTGCACGAGCAGAACTCAACGGCGGAGACAGAAGTTAAATTCTCGTGTAATACATGCACTGAATCCTTCGACAGCAAGTCCGACTACACCAAGCACATGGAAGTGCATGACTCAAACCGCAATTTCCAATGTGACATCTGCCAGGTCACATTCGAGAAGAAATTCAAGCTGCTCTTCCATTTGCAGACGCACAAGATCGAGGACCTGCCCTGCAAAAAGTGCAAAGAAACATTTACAATAAGAGAGAACCTTATTCAACATATAAAGTTGCAGCATATGGGTCCTCGAAATATGGACTTTCAGTGTCCGCAGTGCAATATAGGGCAGTACGACACCCGTGATCTGAAACTGCACATGTTGAATGCACACGACGTTAGTATGGGCCCCCTAAACGCCTGCGATCTGTGCGGGGAGAGCTATTCCACTGCAGCCCAATACTATAAACACATGCACGACAAACATGACACAATCAGCAAAACATGCAACGAATGTGAGAAGTACTTTGATTCGAGAAAAGCCTTCGATAAGCACATACTGGCGCATTACATGTAA
Protein Sequence: MSVKLDDTVCRVCLSSCGNIPIFDGCGKDDQFRYCTSLEANVDDGLPSKLCKKCNDHLKVAYDFRFQAIYAEKYFRKTIFLPSFKKEDTEGTADISDVRDCTDELDENMAEIDMLLAIHTETVDEGDEDDDDMNNSGFYDDDESVDENRKHIEIIGMDTFEKEQREQKDQKVKIEIAAVPPPLVSSTVCTLEYVPPKPVTGIPAESPQPATTSSNTMPNVDINSLQQYTTSSPFSTQSVQDVQIDHGTETSLQLEIIPIVKNDPSTYDFTTTATVTDAYDAYNAPTHIQYQQPMSMHLQYEQPSATLPLQESVSVADNYEFPYQPQFSTYTAQTIEIRPANQAISPAQQEQQNQIVSIVRTETQPETTTKTENLNPKPKKAKREGHSRRDKIECNICGSIFTHLNSLKTHLLKHSGEKPFRCEFCDKAFARKTVLNIHRRLHTGEKPYQCPLCSSAYVTKEALTANHEQEVGANFRKDKVSYICSICNKSRCSKYSLASHMKTHSSDAKARRKMVRRKKEKSGGSNGTATTSAPHKYSCKICQKGFPNKWELSTHAESHDMHKTFECDVCQRTFEKKFQLLYHLQTHDGGDELVKAKVQPAIENRESADKVTEKSVQKQLPTGKKPKRKLSARKRHKRKAKNANAAGDEADEPLEEEENDDEDDKDFELVKAEKDTKKRTIRAQRENLKALRAGSKIECHICEAVFTHPTSLKTHMLVHSGERPFKCDHCDKSFARKTVLNIHRRLHTGEKPYKCPLCDSAYVTKDALMRHMSKDHDDDREADRIKFTCGICHKAMGTKYSLQAHMKLHEQNSTAETEVKFSCNTCTESFDSKSDYTKHMEVHDSNRNFQCDICQVTFEKKFKLLFHLQTHKIEDLPCKKCKETFTIRENLIQHIKLQHMGPRNMDFQCPQCNIGQYDTRDLKLHMLNAHDVSMGPLNACDLCGESYSTAAQYYKHMHDKHDTISKTCNECEKYFDSRKAFDKHILAHYM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00313679;
90% Identity: iTF_00314558; iTF_00314557; iTF_00311232; iTF_00316190;
80% Identity: -