Basic Information

Insect: Cheilosia vernalis
Gene Symbol: -
Assembly: GCA_949126925.1
Location: OX421360.1:56871103-56874311[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00017 0.022 16.0 1.1 2 23 394 415 393 415 0.97

2 16 2e-05 0.0026 18.9 1.0 1 23 421 443 421 443 0.98

3 16 0.096 12 7.4 0.0 1 17 449 465 449 466 0.94

4 16 3.8e-05 0.0048 18.1 3.5 1 23 483 505 483 505 0.98

5 16 5.6e-05 0.0071 17.5 0.2 1 23 538 560 538 560 0.97

6 16 8.1e-05 0.01 17.1 1.8 1 23 566 588 566 588 0.98

7 16 8.8e-06 0.0011 20.1 1.0 2 23 699 720 698 720 0.97

8 16 5.1e-06 0.00064 20.8 3.1 1 23 726 748 726 748 0.98

9 16 0.003 0.38 12.1 0.6 1 23 754 777 754 777 0.97

10 16 0.0002 0.025 15.8 1.2 1 23 788 810 788 810 0.98

11 16 7.5e-06 0.00094 20.3 1.4 1 23 822 844 822 844 0.98

12 16 0.018 2.3 9.6 2.0 1 23 850 872 850 872 0.97

13 16 0.00013 0.016 16.4 0.6 2 23 878 900 877 900 0.95

14 16 0.12 15 7.1 0.2 1 23 908 931 908 931 0.95

15 16 0.00072 0.09 14.1 0.5 3 23 941 962 940 962 0.93

16 16 0.00081 0.1 13.9 0.8 2 23 968 989 967 989 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00017	0.022	16.0	1.1	2	23	394	415	393	415	0.97
2	16	2e-05	0.0026	18.9	1.0	1	23	421	443	421	443	0.98
3	16	0.096	12	7.4	0.0	1	17	449	465	449	466	0.94
4	16	3.8e-05	0.0048	18.1	3.5	1	23	483	505	483	505	0.98
5	16	5.6e-05	0.0071	17.5	0.2	1	23	538	560	538	560	0.97
6	16	8.1e-05	0.01	17.1	1.8	1	23	566	588	566	588	0.98
7	16	8.8e-06	0.0011	20.1	1.0	2	23	699	720	698	720	0.97
8	16	5.1e-06	0.00064	20.8	3.1	1	23	726	748	726	748	0.98
9	16	0.003	0.38	12.1	0.6	1	23	754	777	754	777	0.97
10	16	0.0002	0.025	15.8	1.2	1	23	788	810	788	810	0.98
11	16	7.5e-06	0.00094	20.3	1.4	1	23	822	844	822	844	0.98
12	16	0.018	2.3	9.6	2.0	1	23	850	872	850	872	0.97
13	16	0.00013	0.016	16.4	0.6	2	23	878	900	877	900	0.95
14	16	0.12	15	7.1	0.2	1	23	908	931	908	931	0.95
15	16	0.00072	0.09	14.1	0.5	3	23	941	962	940	962	0.93
16	16	0.00081	0.1	13.9	0.8	2	23	968	989	967	989	0.96

Sequence Information

Coding Sequence: ATGTCTGTCAAGTTGGACGACACAGTTTGCCGCGTATGTTTAAGTTCCTTTGGCAACATACTAATCTTTGATGGATGCGGCAAAGATGATCAATTTCGATACTGCACTTCTTTGGAGGCGAACGTGGACGATGGACTGCCGTCTAAGCTCTGCAAGAAGTGCAACGATCATTTGAAGGTTGCCTATGACTTCCGATTTCAGGCAATTTATGCCGAGAAATATTTCAGGAAGACGATATTTTTGCCTTCTTTCAAAAAAGAAGACACCGAAGGGAGTACAGACATCTCGGATGTGCGCAACTGTTCCGATGAATTGGATGAGAATATGGCTGAGATTGATATGTTGCTAGCAATACACACTGAAACCGTCGATGACGGCGACGAAGACAATGACGATATGAATAATTCTGGCTTCTACGATGATGACGAGAGTGTCGATGAGAACAGAAAACATGTTGAAATCATTGGCATGGATACTTTCGAGAAGGAGCAACGAGAACAGAAGGATCAGAAAGTAAAAATTGAATTAGCTGCTGCACCTCAACCGCTTGTGTCATCAACTGTGTGCACTATGGAATATGTGCCGCCGAAACCTATAACAGGCATACCCGCGGACTCACCACAACCTGCAACAGCAAGCAACAATACGATGCCCAATGTAGACATAAATGACTTACAACAGTATACAGCTTCAAGTCCTTTTTCCACACAATCAGTGCAAGATGTGCAGATCGATCATGGAACCACCGAAACATCCCTCCAATTAGAGATCATCCCAATCATGAAGAATGATCCATCCACGTATGACTTCAGTACTACCGCTACAGTTACCGACGCCTATGATGCATATAACGCTACGGGGCACATTCAATACCAACAGCCTATGTCCATGCAGCTGCAATACGAGCAAACCACAGTGACATTGCCCTTGCAGGAATCTGTTTCTGTTCCAGACAACTATGAGTTCCCCTATCAACCACAGTTCTCTACATACACCGCCCAAACAATCGAAATTAGACCTGCGAATCAGACAATTTCTCCAGCTCAGCAGGAGCAACCAGATCAGATCGTTGCAATTGTAAGAACTGAAACTCAACCGAAAACCACCACAAAGACTGAAAATCTGAATCCCAAACCTATAAAGGCTAAACGTGAAGGTCCCAGTCGCAGGGACAAGATCGAGTGCAACATCTGTGGAAGCATCTTCACGCATTTGAACTCGTTGAAGACGCATCTCCTTAAGCACTCTGGTGAAAAACCCTTCCGCTGTGAGTTTTGCGATAAGGCCTTTGCAAGAAAAACTGTCCTCAATATCCACCGACGTCTTCACACTGGAGAGAAACCCTATCAATGTCCGCTTTGCTCAAGCGCCTTTGTGACTAAGGAAGCCTTAACTGCAAATCACGAACAGGAAGTGGGTGCCAATTTCCGCAAGGACAAGGTCGCCTACATCTGCTCCATATGCAACAAGTCGCGTTGCTCCAAGTACTCTTTGGCGTCGCACATGAAGACACACTCGAACGATGCAAGGGCCAGGCGCAAGATTGTTcgacgaaaaaaagaaaaatccgaCGGCAGCAATAGCACGGCAGCTAACAGCGCCCAACTTAAGTACTCATGCAAAATCTGCCAAAAAGGTTTCCCCAACAAATGGGAACTTAGTACCCACGCCGAGTCACATGACATGCACAAGACGTTCGAGTGCGACGTCTGCCAGCGAACATTCGAAAAGAAGTTTCAGTTGCTGTACCATCTGCAGACGCACGATGGTGGCGATGAACTTGTAAAGGCAAAGGTGCAACCAGTGATTGAAAAGCGAGAAAGTGTTGATAAAGTAACGGATAAGTCGGTGCAAAAGCAACTGCCAACtgggaaaaaaccgaaaagaaAACTCTCGGTGAGGAAGCGCCATAAAAGGAAAGCGAAAAGTGCAAATATTGCCAGCGATGAGGCCGAGGAACCacaggaggaagaagaaaatgACAATGAAGATGACAAGGACTTCGAGCTTGTGAAAGTGGACAAAGCCACAAAGAAGAGGACAAATCGAGCACAGCGCGAGAACCTCAAAGCACTACGCGCTGGCAGTAAAATTGAATGTCACATATGCGAGGCTGTATTTACGCATCCGACATCGCTGAAAACGCACATGTTGGTGCATTCAGGTGAGCGCCCCTTCAAGTGCGACCATTGCGATAAGTCATTTGCAAGGAAAACTGTTCTCAATATTCACCGAAGGCTGCACACTGGCGAGAAGCCCTACAAGTGTCCGCTCTGTGACAGTGCCCACGTCACCAAGGATGCTCTAATGCGCCACATGTCGAAGGACCACGACGATGACAGGGAAGCCGATCGAATCAAGTTCACCTGTGGCATCTGCCATAAGGCGATGGGCACCAAGTACTCCCTGCAAGCCCATATGAAACTGCACGAACAGAACTCAACGGCCGAGACCGAAGTCAAGTTCTCGTGTAATACATGCACTGAATCCTTTGACAGCAAGTCCGACTACACCAAGCACATGGAAGTGCATGACTCAAATCGCAATTTCCAATGTGACATCTGCCAGGTCACATTCGAGAAGAAATTCAAGTTGCTCTTCCATTTGCAGACGCACAAGATCGAGGACCTGCCCTGCAAAAAGTGCAAGGAAACATTTACAATAAGAGAGAACCTTATTCAACACATAAAGTTGCAGCATATGGGCCCTCGAAATATGGACTTTCAGTGTCCGCAGTGCAATATCGGGCAGTACGACACCCGTGATCTGAAACTGCACATGTTGAATGCACACGACGTGAGTATGGGCCCCCTAAACGCCTGCGATCTGTGCGGGGAGAGCTATTCCACTGCAGCCCAATACTATAAACACATGCACGACAAACATGACACAATCAGCAAAACGTGCAACGAATGTGACAAGTACTTTGATTCGAGGAAGGCCTTCGATAAGCACATTCTGGCGCACTACATGTAA
Protein Sequence: MSVKLDDTVCRVCLSSFGNILIFDGCGKDDQFRYCTSLEANVDDGLPSKLCKKCNDHLKVAYDFRFQAIYAEKYFRKTIFLPSFKKEDTEGSTDISDVRNCSDELDENMAEIDMLLAIHTETVDDGDEDNDDMNNSGFYDDDESVDENRKHVEIIGMDTFEKEQREQKDQKVKIELAAAPQPLVSSTVCTMEYVPPKPITGIPADSPQPATASNNTMPNVDINDLQQYTASSPFSTQSVQDVQIDHGTTETSLQLEIIPIMKNDPSTYDFSTTATVTDAYDAYNATGHIQYQQPMSMQLQYEQTTVTLPLQESVSVPDNYEFPYQPQFSTYTAQTIEIRPANQTISPAQQEQPDQIVAIVRTETQPKTTTKTENLNPKPIKAKREGPSRRDKIECNICGSIFTHLNSLKTHLLKHSGEKPFRCEFCDKAFARKTVLNIHRRLHTGEKPYQCPLCSSAFVTKEALTANHEQEVGANFRKDKVAYICSICNKSRCSKYSLASHMKTHSNDARARRKIVRRKKEKSDGSNSTAANSAQLKYSCKICQKGFPNKWELSTHAESHDMHKTFECDVCQRTFEKKFQLLYHLQTHDGGDELVKAKVQPVIEKRESVDKVTDKSVQKQLPTGKKPKRKLSVRKRHKRKAKSANIASDEAEEPQEEEENDNEDDKDFELVKVDKATKKRTNRAQRENLKALRAGSKIECHICEAVFTHPTSLKTHMLVHSGERPFKCDHCDKSFARKTVLNIHRRLHTGEKPYKCPLCDSAHVTKDALMRHMSKDHDDDREADRIKFTCGICHKAMGTKYSLQAHMKLHEQNSTAETEVKFSCNTCTESFDSKSDYTKHMEVHDSNRNFQCDICQVTFEKKFKLLFHLQTHKIEDLPCKKCKETFTIRENLIQHIKLQHMGPRNMDFQCPQCNIGQYDTRDLKLHMLNAHDVSMGPLNACDLCGESYSTAAQYYKHMHDKHDTISKTCNECDKYFDSRKAFDKHILAHYM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00313679;
90% Identity: iTF_00315370;
80% Identity: -