Csis037942.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chalcis sispes
Gene Symbol
prdm10
Assembly
GCA_949987625.1
Location
OX465098.1:69024238-69028441[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0072 1.3 10.8 5.5 1 23 608 630 608 630 0.91
2 9 7.1e-05 0.013 17.1 1.6 2 23 639 660 638 660 0.97
3 9 6.7 1.3e+03 1.5 0.0 2 12 668 678 667 683 0.83
4 9 9.2e-05 0.017 16.8 3.7 1 23 696 718 696 719 0.95
5 9 0.02 3.7 9.5 3.2 1 23 724 746 724 746 0.97
6 9 8.4e-06 0.0016 20.1 1.5 1 23 752 775 752 775 0.96
7 9 0.0017 0.32 12.8 1.0 1 23 808 831 808 831 0.97
8 9 3.8e-05 0.0071 18.0 2.4 1 23 853 876 853 876 0.97
9 9 0.0039 0.73 11.7 3.4 3 23 914 935 914 935 0.98

Sequence Information

Coding Sequence
atggaCCAAGGGGGCCCTCCTGAGGGGGCCCCTGTTGTCGTTGCTGACCCCATGGATATGACTATCATTGACAAAGTTTGCACCGAATCAAATTGGCCTGATGATAACATGGTATCATCATCAACATTTTGTGATAATCCCAGAAAgcttaataataaacttttatttttgacagTTGAATATGTAGAAGATCAATCCAGAGACTTTGGTAGAATGTATCCACCTTATGAAGCAGTCTCTTTTTCATCTCGAGCAAATTCTCCTTTATCGGAATTTGAACACCGTGTCAGTCCTCATGATCCAAATATGAGTTCTGCTGCAAGATATTCTCCAACTCCAGTTCCACTGCCTTCTTCACCTTTTCATAACTCAGTAGTTGTCTTACAAGAGCCTTCCTCACCTCTTATATCAACCTCAGAATCTGCTGTGCGAATTACTAATGGCTATTCTTCACAATTAACTGAGCAATCATCAACTCCTAGTATGTCACAAAGTGATAATTCTGAAGATTTTACTGACAGCACAAGTGATGGATTGGTTTCAAGTGTTGGAAATGAATTAATGTTGATACAAGGGTCAAATTCAGATTTGGAACCTTCATCTACTCCACTCATGTTGGCAGGAATACCAGGATCAGATTTAGCTCTTACAAGAGATTTTCTAGTAATGCAAGAAGACCAAATCAATGTTAtcaattctataaaattaaattcaaatcttGAATCTAATATAAACCAAGTGACAGAATCTATTTTACCACATATAATTGATGAAGAAACTAACGCAcaaataacaacaataaaaaattataaaaaaccaTCTGAACAATCTGTGCAAATATCTGATTCAGATAAGAAAGATATTAATTGGTGCAAAGATCAAAGCAATGAAGATAATAGTTTATgGTATGAAGACTGTGATAGCACTTGCACAGATGCAGCAGATTGCACTTTGCACAGTGTGTGCACAATTGCAGATCAGCCAGTTCCTTCTAGAGCTGTAGCTACATTACCAGGCCTCTACTTATCAATTGATAAAGTTCCATCTTCTGATGTCGTTAATGGCTTGTTAGAATATGGAGTTTTTGCTAAACGAAATATTCGTCGACGTACGCAGTTTGGTCCAATTGAAGGAATTTTACATCCTTATGATGGATCACAAATTAATGGCTTACCATTATTATTGGAAACTAAAGAAGAAAgtgaatttttacaaattgatgTATCCGATGAaaattcttCAAATTGGATGCGTTTTGTAAGACCTGCTCAAACTTACGAAGAGCAAAATTTAGTTATATGTCAACTAAATGatggaattatatttttaacaactcGAAATATCATGCCTAATCAAGAATTAAAAGCTGGTCCAAGTCTCGAATATGGAAAACGCAGAAATTTACCTGTTTTGGAACTtgtacacaaaaataatttagATTCTAAAACAGAATTTTCCACGCAATCTTATATAAAAACTAGACCGTTAGAAATTGTCGATGAaaagattcaaaaaaatttaactgcTGAGAATTgtcgaaataattttacaagattacaaaaaaagcgtaaaaatatttgtgaatCATTCGAaaaatatttagaaattgaTGAAGACGCAAATAATGACCTAAATAATTCgatatctttaaaaagtaattgcGATGAATCTCTAAACtataaaaaatctcaaaaattaCATCAGAAcagaatagaaaaagaaaattctccaGATTCCGAATTAGACTTGATGAAACAAGAAATCACACAATCTGATCAaatagatattgaaaaaaaaacaaacattgtTTCATCAAGTGTCTACAAATGCACAATATGCTCCAAAcgtttttcaacaaaattaaaatttcagcaGCACTGCCTAGTACACAATGTCAAAGATAATCAATCACTTTCATgtaatatatgtttaaaaacatttttaaataattcttcttTAACGCGTCATTTAAAAACACACCAAAaaGAAAGACAAACTTTGGAGTGTCCAGTTTGCAGGCAAGCATTTGGCCGCATATTGACGTTAAAGGATTATTCCGAAACCCACCTTAATCAAGATGAAACATTTACTTGTCCTCACTGCCCAAAATCATTTACGAGTTATGCTTTAACTCGCAAACACGCAAGAGCACATCATTTCGATCGAAAGCATGAATGCCAGTTTTGTTTGAAATGTTTTCCTGCCGCAGATAAATTAAGAATGCATTTATTAAGGCACTCTGACCGCAgggAATTCCAATGTGCAAATTGTggaaaacaatttaaaagaaaagataaacttAAAGATCATGTAACTCGTGTACATTTTACACAAAAGACTAATAAGGACCAAATTTCATCGAATAATCGTGCCAAAAAAACTATCCCTAAGacAAATCCTGTAGATTGTGAtcgatttatttacaaatgtcGTCGTTGCCAAGTGGGTTTTAAACGCAGGGGTATGCTTGTCAATCATTTAGCCAAAAGACATCCAGATGTACCTCCTGAGTCTGTACCAGAGCTTAGTTTACCAATTTTACGACAAACAAGAGACTATTATTGTCAATATTgcgataaagtgTACAAAAGTAGCAGCAAAAGAAAAGCGCACATTATGAAAAATCACCCAGGTGCAGCCTTACCACCAAGCAATAGAAATAAAGAATTTGATATACCTGGCTTACCAAATCCAACATTTAGTCAAGCTGCTGGTAGTATCAAAACCGAACCACAGGGTTGCCAATGGTGCCATAAACAATATGCTAGTAAGGCAAAACTTTTACAACATCAACGTAAAAAGCATTCTAGTCTAATGGAACCTGCAGATCAGATTCCACGCCCACGAAGCCGTCCTCCGCAGAATCAAAATCAACCGCCGACATCGAGCACAAACACCAGTGCGAATAAATCTAGCGTAATATCTAgcgaatgcaataaaataagcGAGGAATCGCAAGATAAAGAATTTCTTAAGCCACGAATAATACGAATAAACGGTGGCGGCGAGTCACTATCCATCAACAATGAATTCGAGCTTTTAAGCTCGCAATTCGTTCGCGTGCGTGATATGCGCTGA
Protein Sequence
MDQGGPPEGAPVVVADPMDMTIIDKVCTESNWPDDNMVSSSTFCDNPRKLNNKLLFLTVEYVEDQSRDFGRMYPPYEAVSFSSRANSPLSEFEHRVSPHDPNMSSAARYSPTPVPLPSSPFHNSVVVLQEPSSPLISTSESAVRITNGYSSQLTEQSSTPSMSQSDNSEDFTDSTSDGLVSSVGNELMLIQGSNSDLEPSSTPLMLAGIPGSDLALTRDFLVMQEDQINVINSIKLNSNLESNINQVTESILPHIIDEETNAQITTIKNYKKPSEQSVQISDSDKKDINWCKDQSNEDNSLWYEDCDSTCTDAADCTLHSVCTIADQPVPSRAVATLPGLYLSIDKVPSSDVVNGLLEYGVFAKRNIRRRTQFGPIEGILHPYDGSQINGLPLLLETKEESEFLQIDVSDENSSNWMRFVRPAQTYEEQNLVICQLNDGIIFLTTRNIMPNQELKAGPSLEYGKRRNLPVLELVHKNNLDSKTEFSTQSYIKTRPLEIVDEKIQKNLTAENCRNNFTRLQKKRKNICESFEKYLEIDEDANNDLNNSISLKSNCDESLNYKKSQKLHQNRIEKENSPDSELDLMKQEITQSDQIDIEKKTNIVSSSVYKCTICSKRFSTKLKFQQHCLVHNVKDNQSLSCNICLKTFLNNSSLTRHLKTHQKERQTLECPVCRQAFGRILTLKDYSETHLNQDETFTCPHCPKSFTSYALTRKHARAHHFDRKHECQFCLKCFPAADKLRMHLLRHSDRREFQCANCGKQFKRKDKLKDHVTRVHFTQKTNKDQISSNNRAKKTIPKTNPVDCDRFIYKCRRCQVGFKRRGMLVNHLAKRHPDVPPESVPELSLPILRQTRDYYCQYCDKVYKSSSKRKAHIMKNHPGAALPPSNRNKEFDIPGLPNPTFSQAAGSIKTEPQGCQWCHKQYASKAKLLQHQRKKHSSLMEPADQIPRPRSRPPQNQNQPPTSSTNTSANKSSVISSECNKISEESQDKEFLKPRIIRINGGGESLSINNEFELLSSQFVRVRDMR