Bsup014436.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus superbus
Gene Symbol
Snai1
Assembly
GCA_014737385.1
Location
JACXIK010000010.1:342756-349089[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0058 0.4 11.0 0.1 1 23 97 119 97 119 0.95
2 12 1e-05 0.00071 19.6 1.2 1 23 127 149 127 149 0.98
3 12 4.1e-06 0.00028 20.9 0.2 2 23 157 178 156 178 0.97
4 12 4.2e-06 0.00029 20.9 0.7 1 23 184 206 184 206 0.99
5 12 1.6e-05 0.0011 19.0 2.0 1 23 213 235 213 235 0.99
6 12 3e-06 0.00021 21.3 0.6 1 23 241 263 241 263 0.96
7 12 7.7e-06 0.00053 20.0 0.1 1 23 269 291 269 291 0.98
8 12 4.3e-07 3e-05 24.0 1.2 1 23 297 320 297 320 0.96
9 12 2.3e-06 0.00016 21.7 0.5 1 23 326 349 326 349 0.96
10 12 1.5e-06 0.0001 22.3 2.1 1 23 355 377 355 377 0.99
11 12 5.6e-05 0.0038 17.3 0.4 1 23 383 405 383 405 0.94
12 12 0.00017 0.012 15.8 0.1 1 23 411 435 411 435 0.94

Sequence Information

Coding Sequence
ATGGAAGGGGAGGAAGAAAGAATAGAGGAAGAAGAAGAGGAACCTTCTTGTGAACCAGAGGAAATTATTCTAAAAGTTGAGGCTATACCAGAAACAAGTGGTACTGAAGAAAGAAAGAGGATAAAACGAGCAAAAATTACACCAAAAGTTGAACCTCTTCAAGAGCGAATTGTTGCTAGAGATGGCTCTGTATATACCTGTTTGTTATGTACAAACGAAGATGATAAAGCTGTAGGAGATGCAAAGTCCATTATTGCACATGTAAGGAGCGTGCACGAAACTCGTTTATATATTTGCGATATATGTGGGGATGACTTTAAAAAGAGAAATGAACTATCTATTCATCTTGATGATCATGTTGCTAAAGAGGAAGGAGATTTTCAGTGTGAAATATGTAATAGAATATTTAGTAATTTGCGGTTGTTTAGAATTCATAAAAGAATACATTATCCACAAGTGAAATCTTGGCCATGTGAAACTTGTGGTAAACGATACAGTTCCAGAAATTTATTGGAGGAACATATTAATACACATACAGGTGTACGTCCATATGTATGTGAAAGTTGCGGTAAAGATTTTGCTTCAAAATATACTTATAAAGCACATGTAAAAACACATGAAATACGACCTCGTCCTTATGAGTGTTCACAATGTAACAAAACATTTTTGAGCCAACAAAATCTTAATCAACATGAAAGAACTCATAATGGTGTAAAGGAGTATGTTTGCCACCAGTGCGGAAAAGCCTTTGGTTCGCCACATAATTTAGAAGTGCACAATATAGTACATACTGGTTACAAACCATATATATGTAGAGTATGTGGTAAAGCATTTGCCCGCAAAGCTGAAATAAGGGACCATGAAAGAACACATACTGGAGAGAAACCATATCAGTGTGAATTTTGTGGAGCTACATTTAGTCAACGATCAAATTTACAATCGCACAAGCGTGCAACGCACTATAATGATAAACGGTATAAATGTGACGATTGCGGAAAAGGATTTAAACGGCGGAGATTATTAGACTATCATATAAAAGCAGCTCATACTGGTGAAAGACCGTACAAGTGCGATGTATGTACAGCAACATTTGTATATCCCGAACATTTCAAAAAACATATGCGCATACATACTGGAGAGAAACCTTATCTCTGTGAGGTTTGTGGTAAAGCATTTAACAGTCGAGATAATAGAAATGCGCATCGGTTTATACACAGTGATAAAAAACCGTATGAATGTCTAGTATGCGGTATGGGTTTTATGAGAAAACCTTTGTTGTATGCTCATATGCAGACTCAGGGACACTTAAATGATACCATTGTAGTGAATCAACCGCGTCTCACTACGGAAGATGATCAAGTTATAACAATCTCTGATGGCAATGTGGAACTTTTAGTAGATGAAGCGGAAAATGACCAGTTGGATGAAACTGAACTGTATGTAACAGAGTTAAAAGATCATGTTATCATACAGCAGCAAAATGAGGATCAAATGTATAATGAAGAAGATGTATTAAATATTCCGGCAGAGGAAACTGTTGCAGACGAGGAAGTAAATCATCTCGTTGATGGAGAAATGAACTTTGCCGAAAATGAAGTAATGGAATGCAAAACTGAAGATTCGGAGCAAGTAGAAGAGGTATACAACTATAATGAAACGGAAGACGGAGAAACAATAGTTGTACCAACTACCTCAGAGTACAAAGAAGTGGAAGAAGAGAAAAACGCTGTACGATTAGTACAAATTCGATTTCCAACATCAGTTGGTGGAGAAGGCCGAAGTTGGTTAAGCTTAGTACAAAACACGTGA
Protein Sequence
MEGEEERIEEEEEEPSCEPEEIILKVEAIPETSGTEERKRIKRAKITPKVEPLQERIVARDGSVYTCLLCTNEDDKAVGDAKSIIAHVRSVHETRLYICDICGDDFKKRNELSIHLDDHVAKEEGDFQCEICNRIFSNLRLFRIHKRIHYPQVKSWPCETCGKRYSSRNLLEEHINTHTGVRPYVCESCGKDFASKYTYKAHVKTHEIRPRPYECSQCNKTFLSQQNLNQHERTHNGVKEYVCHQCGKAFGSPHNLEVHNIVHTGYKPYICRVCGKAFARKAEIRDHERTHTGEKPYQCEFCGATFSQRSNLQSHKRATHYNDKRYKCDDCGKGFKRRRLLDYHIKAAHTGERPYKCDVCTATFVYPEHFKKHMRIHTGEKPYLCEVCGKAFNSRDNRNAHRFIHSDKKPYECLVCGMGFMRKPLLYAHMQTQGHLNDTIVVNQPRLTTEDDQVITISDGNVELLVDEAENDQLDETELYVTELKDHVIIQQQNEDQMYNEEDVLNIPAEETVADEEVNHLVDGEMNFAENEVMECKTEDSEQVEEVYNYNETEDGETIVVPTTSEYKEVEEEKNAVRLVQIRFPTSVGGEGRSWLSLVQNT