Ador002253.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Apis dorsata
Gene Symbol
-
Assembly
GCA_000469605.1
Location
NW:37523-43602[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00081 0.049 13.2 0.2 1 23 235 258 235 258 0.95
2 9 4e-06 0.00024 20.5 2.1 1 23 263 285 263 285 0.99
3 9 5.7e-07 3.4e-05 23.1 0.6 1 23 291 313 291 313 0.98
4 9 0.0028 0.17 11.5 0.8 3 23 321 342 319 342 0.93
5 9 1.1e-05 0.00064 19.1 1.1 1 23 348 370 348 370 0.93
6 9 4.9e-06 0.00029 20.2 1.1 1 23 376 398 376 398 0.98
7 9 0.00065 0.039 13.5 5.3 1 23 404 426 404 426 0.96
8 9 6.2e-08 3.7e-06 26.2 0.8 1 23 432 454 432 454 0.98
9 9 0.0015 0.092 12.4 1.3 2 23 463 484 462 484 0.96

Sequence Information

Coding Sequence
ATGGAGAATAGGCCGGCACCACTTCGCTCTAGGCGAGTCTGCCGATTTTGTTTGACCGAATCAGAACCACTTTGCTTCATTTATGAACGGGATCATAGCAAACCGTTTCAAGTACCACTTACCCTCCAAATCATGTCTTGCGTCGCCATCGAGGTATACGCAGCTGATGGAATGCCACAAATGATTTGTAATATGTGTCGCTGGAATCTCGATagatcttataaatttaaacttcaaTGTAAAAAGGCAGATGAAGCATTACGAGCTTATCCATTATCTGGTGTCTTGCCAAGACCATTCCCACCAATTCCAAATGATCCTCCTGATATGAACAATAAACGACCTTCGGAACAAAGACCTCAAAGTGAAGGAAATAAGAAACCTCGAGTTGATAATGGTgatagagaaagaagagaaacacgggaaagagatagagaaagggatagagaaagagataggGAAAGGGAtagggaaagggaaagggatagagaaagggaaagagaacgtgagagagatagagaacgtgacagagaaagagaaagagaaagggaaagagaaagagatagacaAGTAGAAAATCAAAGAGACAAAGAAGATCAACATGATTTTTATGAAGAAGAACAAGATGCTGGTAGCGAAGGAGATCAGGATACGAATAGTACTAAAGAGGAACAAAAATTAGAGCCAGGTGAGATAAGAGTACATGCGTGTGATCAATGCGATCGTACGTTTCCTTTGCGACAAGCTCTTGCTTTACACATTCAAAGAGCTCATCGTGATCGTAATTATAAATGCACAGTATGTGACCGCATGttcttttctaaatatgaTCTTGGAAAGCATATGACTACTCATTCGGAAGAGAAACCATTCTCTTGTCCAATTTGTAACAAACAATTCTCAAGAGCAAATTTATTACAACGTCATGAAAAAGTTCATAGAGATGAATTGCGCTATGGTTGTCAACATTGCGATCGTGAATTCTTTACAAcagaagaattagaaaaacatGAGGATTCTGtacataaaaaggaaaaaccgTTCCAAtgcaatatttgcaataaacgTTTTACATATAAACAAGGTTTGGAACGTCATGAAGTGCTGCATAACGAAGATAAGACTTTCGTTTGCGAATATTGTAAGGAAGCATTCCGTACAAGTACCAAGTTAGCTCGTCATTTAACAACTCATGCTGGACATCGACCATACTTATGTAAATTATGCCCACGTTCATTCCTTTTATCCCATCACTTAACAAGACATATGCGAACTCATTCTGTAGAAAAACGTCATGTTTGTGAAGATTGCGGTAAAGCATTCAAACGTAAAGAGAGTTTGGAAGTACATCAATTAACGCACACAAAACGCACAGGTATGGGTTTAACATGCGATGTTTGTCAAGAATCATGTAGAAACAGAGCAGATTATGTTACACATATAAAGCAACATATTGAAGCAGGTGAAAAAATGGGACCAGATGGATTACAACCTGATAATAAAACCAAACTTGAATTGGATTCCGACGAGGATGAAGAGGAAGAACAATACTCGGATGGAGATGATGATTATGAACCGCCAGcatatattgtgaaaaaacTTCCAAAACCAAATAAACCATCGGAAAGCGAAGAAGAACCAGAGAcaacagaaaaagaagaaaatcaaaaagaacAAGTTGTATATGTAAGAAACAAAGAtggaaatatgattaaaaagacAATTAAAACTTTGATGCCTATTCAACGTAGAGAAGTACAAGATaccaaaataaaacaaagtcCCTCGGGTAATCAATCACAATCAAATACGAAACCTTTACAATCTAAACAAACTGAAGAATCCTCAAAGTCTTCCCGCGTAGATGAAACAGAAGCACAAGTACAAAAAATTGTTGCATCTGTGTTTAAGGAACATAAAATACCGCTAAAACATCAAAATGTTCAAGAACAAAGTAAAGAATCATCTATATCTACAAATCAATCTAGATCGCAACAAGGACAAAGTAGTTCACAAAATCAAGTTTctttgaaagatgaaaaatctgAAACTCCCGTATTAGTCAGTGGAACACCAAAAGCTGTAAATACTGTTAAAGTAATAAAGAGAATTGTTGTAAGAAAACCTAGCGGTAATACCGAAACTAGTACATCCACGATAAAAGACGAGGATGGTACTTCTCAAACTCTTAGTACAGGACATAAAGTAACAAAAAGAGTAATCGTTCGTAGAATTATTCGTCAAGGAGATACTACCCGAGAGATAATCATGAATCCTGATGGTACAATAATCGATCCAGCAGAATTGGCCAAGCTTCCAACTGGTAATGTTGTGAAAAGAGTTGTTGTGAAAAAGCCACTTGATAAACATCAAAGTTTGGTTCAAGCTGTATTACAATCGTCCACGGAATCACGACAATCTACTTCGATAAAGAATAACGATTCGGTATTGAACGAATCTccgaaatttgaattaaaaacatCTCAGTCCATAAATGCATCACCTTCAGTAACAAAAACGTCTACATCTACAGCACAAAAACCTACAATAACCGTAGGAGATCAAGAAACTAAGGAAAAATTAGAACAATTGGAAAAAAGAGTAGAGCAACAACgcttaaaaatagaagaattagaAGCTCGTAAACAACAAGAGTATGAACCTATTGAAGAAATGTCACCAGAACGTCATGATGAATCTGATGATGAGCAACAATTACCATTGAAAAGAGTATTtgtaaagaagaaacaaagtaTGTATGACGAAGAACaagaatataatgataatgatgtaACAATGGTTTCTGTAACAACTCCTATATCAACTTCTATAACGACTCCAACGATTTCTGTAACAACTCcaacaacaataaaaatagaagatattaaatctgatatggaaatagaaaaagagaaagaaaaaaataaaattgaagtacAAGTAGAAAATATACCAAAAGATGTTTCCATGATACCAAAAGCAATTTCTATAACAACAGCAATAGCTACAACgccaataacaacaacaacaacagcaacaagtGCTACTATTAGAAAAGAAGGTAAACCATTAATAACCAGTTCTAAAGTCTatggaaataagaaaatcattGTTGTAAAAACGGGAGAATCATCGGAAGTGGAAGAAATGAGTCGAGAATTATGTAACATATTAGATTCATCTGATTCTGTTGTTAAAATGCAAGAATCAATTCTAAGTAATCTCActcaaatttcttctcttgGAGAATCTTCTCAAAAAAGTAATGATGATAAAGCAAAAGCTGGACCTTCGAATTCAGAGGATTATTTGATAAAGGAAGAATCTGCTAAAACCGATTCCCAAGATCAAGAAATGGATATAAAACTAGATAATTCAGTTTCTATGGATGTATCGGATTCCCAAGTATCCGATGTTAAAATAGAATCCGAAGAACAAATTATGGAACAACCtgaacaaaattcaaatttaactaTAGATGAACAGGATCTTTCAGAATCTACAGATATTTTTGAACCATCAGACAATGTATTAGAGGTACAAAAAAGTGAGTTAGGTGATTCTGTAATAGAACTTGATCATGAAAATCATACAATCAATTTAAACGATACTAATGATAGTCAAGATAGTCTTGAGGATAAACTTCAACAAATGGAAGGTTAA
Protein Sequence
MENRPAPLRSRRVCRFCLTESEPLCFIYERDHSKPFQVPLTLQIMSCVAIEVYAADGMPQMICNMCRWNLDRSYKFKLQCKKADEALRAYPLSGVLPRPFPPIPNDPPDMNNKRPSEQRPQSEGNKKPRVDNGDRERRETRERDRERDRERDRERDRERERDRERERERERDRERDRERERERERERDRQVENQRDKEDQHDFYEEEQDAGSEGDQDTNSTKEEQKLEPGEIRVHACDQCDRTFPLRQALALHIQRAHRDRNYKCTVCDRMFFSKYDLGKHMTTHSEEKPFSCPICNKQFSRANLLQRHEKVHRDELRYGCQHCDREFFTTEELEKHEDSVHKKEKPFQCNICNKRFTYKQGLERHEVLHNEDKTFVCEYCKEAFRTSTKLARHLTTHAGHRPYLCKLCPRSFLLSHHLTRHMRTHSVEKRHVCEDCGKAFKRKESLEVHQLTHTKRTGMGLTCDVCQESCRNRADYVTHIKQHIEAGEKMGPDGLQPDNKTKLELDSDEDEEEEQYSDGDDDYEPPAYIVKKLPKPNKPSESEEEPETTEKEENQKEQVVYVRNKDGNMIKKTIKTLMPIQRREVQDTKIKQSPSGNQSQSNTKPLQSKQTEESSKSSRVDETEAQVQKIVASVFKEHKIPLKHQNVQEQSKESSISTNQSRSQQGQSSSQNQVSLKDEKSETPVLVSGTPKAVNTVKVIKRIVVRKPSGNTETSTSTIKDEDGTSQTLSTGHKVTKRVIVRRIIRQGDTTREIIMNPDGTIIDPAELAKLPTGNVVKRVVVKKPLDKHQSLVQAVLQSSTESRQSTSIKNNDSVLNESPKFELKTSQSINASPSVTKTSTSTAQKPTITVGDQETKEKLEQLEKRVEQQRLKIEELEARKQQEYEPIEEMSPERHDESDDEQQLPLKRVFVKKKQSMYDEEQEYNDNDVTMVSVTTPISTSITTPTISVTTPTTIKIEDIKSDMEIEKEKEKNKIEVQVENIPKDVSMIPKAISITTAIATTPITTTTTATSATIRKEGKPLITSSKVYGNKKIIVVKTGESSEVEEMSRELCNILDSSDSVVKMQESILSNLTQISSLGESSQKSNDDKAKAGPSNSEDYLIKEESAKTDSQDQEMDIKLDNSVSMDVSDSQVSDVKIESEEQIMEQPEQNSNLTIDEQDLSESTDIFEPSDNVLEVQKSELGDSVIELDHENHTINLNDTNDSQDSLEDKLQQMEG