Bsko005847.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus skorikovi
Gene Symbol
-
Assembly
GCA_014737355.1
Location
JACXIH010000081.1:2496896-2501464[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0037 0.34 11.6 0.2 1 23 239 262 239 262 0.95
2 9 4.2e-06 0.00039 20.9 2.3 1 23 267 289 267 289 0.99
3 9 7.9e-07 7.3e-05 23.1 0.6 1 23 295 317 295 317 0.98
4 9 0.0039 0.36 11.5 0.8 3 23 325 346 323 346 0.93
5 9 1.5e-05 0.0014 19.1 1.1 1 23 352 374 352 374 0.93
6 9 6.8e-06 0.00063 20.2 1.1 1 23 380 402 380 402 0.98
7 9 0.0009 0.084 13.5 5.3 1 23 408 430 408 430 0.96
8 9 8.6e-08 8e-06 26.2 0.8 1 23 436 458 436 458 0.98
9 9 0.0021 0.2 12.3 1.3 2 23 467 488 466 488 0.96

Sequence Information

Coding Sequence
ATGGAGAACAGGCCGGCGCCGCTCAGGTCCAGGCGGGTCTGTCGATTTTGCCTAACCGAAACTGAACCACTTTCCTTTATCTATGAAAGAGATCATAGTAAACCATTTCAAGTGCCACTTACACTGCAGATCATGTCGTGCGTCGCCATCGAGGTGTATGCAGCTGATGGAATGCCACAGATGATATGCAGTATGTGTCGTTGGAATTTAGACAGATCTTATAAATTTAAACTTCAGTGCAAAAAAGCAGACGAAGCGTTGAGAGCTTATCCATTGTCTGGTGTCTTACCAAGACCATTTCCACCAATCCCGAATGATCCTCCTGATATGAACAATAAACGACCTTTGGAGCAAAGATCTCAAAATGAAGGAAATAAAAAGCCTCGAGTTGATAGTTGCGATAGGGAGAGACGAGAAACACGAGAAAGAGATAGAGAAAGGGAAAGGGATAGGGATCGAGAAAGAGAAAGAGAAAGGGAAAGGGAAAAAGAAAGAGAAAGAGATAGGGAACGTGAAAGAGATAGGGACCGTGACAGAGAAAGGGAAAGAGAAAGAGATAGGGAACGTGAAAGAGATAGGCAAGTAGAAAAACAAAGAGAGAAGGAAGAACAACATGATTTTTATGAGGAGGAACAAGATGCTGGCAGTGAAGGAGATCAAGATACAAATAGCACTAAAGAGGAGCGAAAATTAGAGCCAGGTGAGATAAGAGTACATGCATGTGATCAATGTGATCGTACTTTTCCACTACGACAGGCTCTTGCTTTGCACGTTCAACGAGCTCATCGTGATCGTAATTATAAATGTACAGAATGTGATCGTATGTTCTTTTCTAAATATGATCTTGGGAAACATATGACTACGCATTCAGAAGAGAAACCATTCTCCTGCCCGATATGTAACAAACAATTTTCAAGAGCAAATTTGTTACAACGTCATGAAAAAGTTCATAGAGATGAATTGCGTTATGGTTGTCAGCATTGTGATCGCGAATTCTTTACAACCGAAGAATTAGAAAAGCATGAGGATTCCGTACATAAAAAGGAGAAACCTTTCCAATGTAACATTTGCAACAAACGTTTCACGTACAAACAGGGTTTGGAACGTCATGAGGTACTACATAACGAAGATAAGACTTTTGTTTGCGAATATTGTAAGGAAGCGTTCCGTACAAGTACGAAGCTAGCTCGTCATTTAACAACGCATGCTGGACATCGACCATATTTATGTAAACTATGCCCTCGTTCATTCCTTCTATCTCATCATTTAACTAGACATATGCGAACACATTCTGTAGAAAAACGCCATGTTTGCGAAGATTGCGGTAAAGCATTCAAGCGTAAAGAGAGTTTGGAGGTACATCAGTTAACGCACACAAAACGCACAGGTATGGGATTGACATGTGATGTCTGCCAGGAATCATGCAGAAATAGGGCAGATTATGTCACACATATAAAACAACATATTGAAGCAGGTGAAAAAATGGGACCAGATGGATTACAACCAGACAATAAAACTAAACTTGATTTGGATTCTGATGAAGATGAAGAAGAAGAACAATATTCAGATGGAGATGATGATTACGAACCACCAGCATATATTGTGAAAAAGCTTCCAAAACCACTTAAGCCATCAGAAAGCGAAGAAGAACAAGAAAGATCAGAAAAGGAGGAAAATCAAAAAGAACAAGTTGTATATGTAAGACATAAAGATGGAAATATGATAAAAAAGACAATTAAAACTTTGATGCCTATTCAGCGTAGAGAGGTACAAGACAGCAAGATAAAACAAAGTCCAACTACCAACCAATCTCAATCAGCCACAAAACCTCCACAGTCTAAACAAAATGAAGAACCTTCAAAGTCTTCCCGCGTTGATGAAACGGAAGCACAAGTTCAAAAAATTGTTGCATCTGTGTTTAAGGAGCATAAGATACCTCTGAAACATCAAAATGTTCAAGAACAAAATAAAGAACCATCTACACCTACGAATCAATTAAGACCTCAACAAGGACAAAGTAGTTCACAAAATCAAATTTCTACGAAAGACGAAAAATCTGAAATTCCTATAGCGGTCAGTAATACACCAAAAGCTGTAAACACTGTTAAAGTAATAAAGAGAATCGTTGTGAGGAAACCTGGTAATACTGAGACTAGTACATCTACAGTAAAAGATGAAGATGCAACAGGTAGCACTTCTCAAACATCTAGTACAGGTCACAAAGTAACAAAAAGAGTAATTGTTCGTAGAATTATTCGTCAGGGAGATACAACCCGAGAAGTTATTATGAATCCTGATGGTACGATAATCGATCCGGCAGAATTAGCAAAGCTACCAACTGGTAACGTTGTAAAGAGAGTTGTCGTAAAGAAGCCACTTGATAAACACCAAAGTTTGGTTCAAGCGGTGTTGCAGTCAACTACGGATATTCGGCAACCAACTACTACAATAAAAAATAACGATACAGTACTAAGCGAATCTCCGAAATTTGAATTAAAAACATCTCAGTCCATAAATGCATCGTCTTCGGTAACAAAAACAACTGTATGTCCTGCATCGAAACCTGCATTAACGGTAGGAGATCAAGAGACTAAAGAAAAATTAGAACAGCTGGAGAAGAGAGTCGAACAACAGCGCTTAAAGATTGAAGAATTAGAAGCTCGTAAGCAACAAGAATATGAACCTATTGAAGAAATGTCTCCTGAACGTCACGACGAATCCGACGATGAACAGCAATTACCATTAAAAAGAGTGTTTGTAAAGAAAAAGCAAAGTATGTACGATGAAGAACAAGAATATAATGACAATGATGTAGCAATAACTTCCTCAATAACTTCCTCTGTAACAACCTCTGTAACAACTTCTGCAACGACTCCAATAACAACAATAAAAATAGATGATACTCAGCCTGAACCAGAAAAGGAGAAAGAAAAAAGTAAATCTGAGGTACAAGTAGAAAATATATCAAAGGATATTACGGTAACGCCGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTTAACACTAGAAGAGAAAGTAAACCATTGATAACCAGTTCCAAAGTCTATGGAAATAAAAAGATTATTGTTATAAAAACAGAAGACGCATCGGAAGTGGAAGAAATGAGTCGGGAATTATGTAGTATATTAGATTCAGCTGATTCTGTAGTCAAGATGCAAGAAACAGTTTTAAGTAACCTCACTCAAATATCTTCTATTGGCGAATGTTCTCAGAAGAACTATAATGATAAACCAATAGCTGGACCATCTATCTCCGAGGATTATTCAGAGAAAGAAGAGGCTGTTGTTGAAACTACTTCTCAGGATCAAGAAGTAGATATTAAGTTAGAGAATGCTGTACCCATGGATGTGTCTGATCCCCAAGAATCTGATATTAAAATGGAACCAGTATCTCAAGAACAAGTTATGGAACAACCTGAACAAAATTCAAATTTGACTTTAGACGAACAAGATCTTTCAGAATCAACAGATATTTTTGAACCATCGGATAATGTATTAGAGGTACAAAAGAGTCAATTGGACGATTCCGTGATAGAACTCGAACATGGAAGTCACGCAATCAGTTTAAATGACACTAATGACAGTCAGGATAGCCTCGAAGACAAACTTCAACAAATGGAAGGTTGA
Protein Sequence
MENRPAPLRSRRVCRFCLTETEPLSFIYERDHSKPFQVPLTLQIMSCVAIEVYAADGMPQMICSMCRWNLDRSYKFKLQCKKADEALRAYPLSGVLPRPFPPIPNDPPDMNNKRPLEQRSQNEGNKKPRVDSCDRERRETRERDRERERDRDREREREREREKERERDRERERDRDRDRERERERDRERERDRQVEKQREKEEQHDFYEEEQDAGSEGDQDTNSTKEERKLEPGEIRVHACDQCDRTFPLRQALALHVQRAHRDRNYKCTECDRMFFSKYDLGKHMTTHSEEKPFSCPICNKQFSRANLLQRHEKVHRDELRYGCQHCDREFFTTEELEKHEDSVHKKEKPFQCNICNKRFTYKQGLERHEVLHNEDKTFVCEYCKEAFRTSTKLARHLTTHAGHRPYLCKLCPRSFLLSHHLTRHMRTHSVEKRHVCEDCGKAFKRKESLEVHQLTHTKRTGMGLTCDVCQESCRNRADYVTHIKQHIEAGEKMGPDGLQPDNKTKLDLDSDEDEEEEQYSDGDDDYEPPAYIVKKLPKPLKPSESEEEQERSEKEENQKEQVVYVRHKDGNMIKKTIKTLMPIQRREVQDSKIKQSPTTNQSQSATKPPQSKQNEEPSKSSRVDETEAQVQKIVASVFKEHKIPLKHQNVQEQNKEPSTPTNQLRPQQGQSSSQNQISTKDEKSEIPIAVSNTPKAVNTVKVIKRIVVRKPGNTETSTSTVKDEDATGSTSQTSSTGHKVTKRVIVRRIIRQGDTTREVIMNPDGTIIDPAELAKLPTGNVVKRVVVKKPLDKHQSLVQAVLQSTTDIRQPTTTIKNNDTVLSESPKFELKTSQSINASSSVTKTTVCPASKPALTVGDQETKEKLEQLEKRVEQQRLKIEELEARKQQEYEPIEEMSPERHDESDDEQQLPLKRVFVKKKQSMYDEEQEYNDNDVAITSSITSSVTTSVTTSATTPITTIKIDDTQPEPEKEKEKSKSEVQVENISKDITVTPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNTRRESKPLITSSKVYGNKKIIVIKTEDASEVEEMSRELCSILDSADSVVKMQETVLSNLTQISSIGECSQKNYNDKPIAGPSISEDYSEKEEAVVETTSQDQEVDIKLENAVPMDVSDPQESDIKMEPVSQEQVMEQPEQNSNLTLDEQDLSESTDIFEPSDNVLEVQKSQLDDSVIELEHGSHAISLNDTNDSQDSLEDKLQQMEG