Basic Information

Insect: Anopheles coluzzii
Gene Symbol: L
Assembly: GCA_016097175.1
Location: CM027929.1:16425908-16432279[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.65 34 4.9 5.7 1 23 39 61 39 61 0.98

2 16 5.3e-06 0.00028 20.8 3.7 1 23 67 89 67 89 0.99

3 16 1.6e-05 0.00085 19.3 0.3 1 23 95 117 95 117 0.98

4 16 7 3.7e+02 1.6 0.1 2 23 223 246 222 246 0.78

5 16 0.11 5.8 7.3 0.1 2 23 296 318 295 318 0.96

6 16 0.23 12 6.3 0.2 1 23 659 681 659 681 0.95

7 16 0.00035 0.018 15.1 0.2 1 23 756 779 756 779 0.93

8 16 0.0025 0.13 12.4 0.8 1 23 786 809 786 809 0.97

9 16 0.0026 0.14 12.4 1.5 1 23 841 863 841 864 0.96

10 16 0.45 24 5.3 0.2 1 23 1169 1193 1169 1193 0.91

11 16 0.00065 0.034 14.3 0.2 2 23 1202 1224 1201 1224 0.96

12 16 0.0047 0.25 11.6 0.1 1 23 1231 1253 1231 1253 0.98

13 16 2.4 1.3e+02 3.0 1.2 2 20 1261 1279 1261 1282 0.94

14 16 0.005 0.26 11.5 0.2 1 23 1490 1512 1490 1512 0.96

15 16 0.013 0.69 10.2 0.1 1 20 1522 1541 1522 1545 0.95

16 16 0.04 2.1 8.7 0.3 1 23 1553 1575 1553 1575 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.65	34	4.9	5.7	1	23	39	61	39	61	0.98
2	16	5.3e-06	0.00028	20.8	3.7	1	23	67	89	67	89	0.99
3	16	1.6e-05	0.00085	19.3	0.3	1	23	95	117	95	117	0.98
4	16	7	3.7e+02	1.6	0.1	2	23	223	246	222	246	0.78
5	16	0.11	5.8	7.3	0.1	2	23	296	318	295	318	0.96
6	16	0.23	12	6.3	0.2	1	23	659	681	659	681	0.95
7	16	0.00035	0.018	15.1	0.2	1	23	756	779	756	779	0.93
8	16	0.0025	0.13	12.4	0.8	1	23	786	809	786	809	0.97
9	16	0.0026	0.14	12.4	1.5	1	23	841	863	841	864	0.96
10	16	0.45	24	5.3	0.2	1	23	1169	1193	1169	1193	0.91
11	16	0.00065	0.034	14.3	0.2	2	23	1202	1224	1201	1224	0.96
12	16	0.0047	0.25	11.6	0.1	1	23	1231	1253	1231	1253	0.98
13	16	2.4	1.3e+02	3.0	1.2	2	20	1261	1279	1261	1282	0.94
14	16	0.005	0.26	11.5	0.2	1	23	1490	1512	1490	1512	0.96
15	16	0.013	0.69	10.2	0.1	1	20	1522	1541	1522	1545	0.95
16	16	0.04	2.1	8.7	0.3	1	23	1553	1575	1553	1575	0.95

Sequence Information

Coding Sequence: ATGTTTATTCAATTCGGTTTGCAAAGATCGAGCGCGGGCGCGAATCAAACGTACACCAGCAGCACCATCGCCATCATCATCATCATCGCTGAGAGCCACACGGAGCATATGCCATTCAAATGTGAGTACTGTGCCCGACTGTTCAAGCACAAACGATCGCGGGATCGCCATACGAAGCTGCATACCGGCGATCGACGCTATCGCTGTCTGCACTGTGAGGCTGCATTCTCCCGAAGTGATCATCTGAAGATACACATGAAAACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGAGGCTACAATACGGCCGCAGCGCTAACGAGCCATATGCAAAATCACAAGAAGCAGCTGGCCCTGACCGGGAGTCCCAACCTTACGTACAGTCCACGCTCCACCACAAGCTCCCTGTCGAGTGGAGGAGGAAGTGGTGGTGGTGGTAAGCGAGGGGCAAAGTTCTCGCCCTACTCCAACGACCCACTGATGCTGATGAGCCGCGGCAACTCCAAACTGTCCTCGTCTCTTTCCAAAGCCGCAAGTAATCGAACTCCAACACCTGGGAGTACGGCCGGCGGTGGTGGCAATGCAGCTCTGGGAGGTCTGGGAAGTGGTGCGGGAGGTGGTACCGGCACCAACCATCATCAGCAGGATCTGCTCTCCTGTCCGTACTGTACGCGGACGGATTTTGGGACGCTCGAACAGCTCGGGCTCCATGTGCAGTCGATGCACGGGCATGGTGGTGCTGGTGCATTGGGATTGCTTGCTGGCGACTCCTCAATGTCTTACTTCACACCTGCCGGTGGACGACGTGCAGTGACACCCGATGGGAGCAACGTCCCGCTCTCACTCGGTGGTCTCAGTCCGTATCCACCGATTAGCTGCGAGTTCTGCACGATGAAGTTCCCAACCGTTCCGCTCATGTTTGCCCATCTCAAGACAGCTCATCTGGATCGGTTGGCTGGCAGTGGTGGTGGTCATCAACGAAGCTCACCATCGAATGGTACCGGCAGTCCGCTCGGGTCACGTCCTCCCAGTGGGTTCCATCCGCTAGACCAGCTGCACTTTAACAAGAGCCTGCTTGGAAGTGCTTTCCCCTCCTTCTACGGTGGTGGTGGTGGTGGTGGTGGTTCTTCCAACAGCCTTGCCGGAATGTCCGGAGGCAGTATTAAAGCGGAGCGCCGGCTAATGGCCGAACGTGATGAAAATGGAAATGAAGAAGAAGCGGGAGGTAGAAAGCGGCAGCGCAGAGGAGACGATGGAGCAGATGTTAGGGGGAGCATGTCGAAACGGGACAAGCAGGAAAAGGAGGAGGAACAAGCTATTGAAGGTGATGAGGAGGACGATGAGGATGATGATAATGACGTTGAGGGAGAAGATAATGAGGAGGGAGAAAGTGAGGCCCATGGAGCAAACAATCGATGTGAGGAGTCCGTTGACTACAAGGAAGAAGCGATCGATACGAAGATCACACCGATCAAGCAGGAGCGAAAGGAAGAGCCTGCTGAGGGTGAGCCATCTCCTTCGACTTCTGCACGATCGTCTCCCTGTGGTGATTCCCTGGAGTTGGGAAGTGGACGTGCCGGAAGTCACCCATCGGGACGTACAAGTCCAGCAGAGCAACTCACCCCAACAGACCTGAGTCAGCCGAAGGTGAAGCGTCTCAAGCTGGAGACGCCCGAAGAAGACTCACTGACCGACGGGGCGGATAGGAAGAGGATGATGATGACGGGGTCAGCAGCATCTGTAAGATCTCAAACAACTCGCGAGCAACACAAACATCGTGGTCCAGCAACAACCGCAACTGCAACAGGTCGTCGAGATAGTGAAGCGAAAGACTCACACCTCCAGCACGGCTCACTGATGCACTCCTCCACTTCGAGCAGCAACGTCCAACACTCCCAGCAGATGGGAGCCCCTACTTCTACCGGAACATCATCCCAGCACCACCATCAACCTCCCGGCGCATACCTCTGCAATCAATGCAATGCCGCACTGCCCGATTTCGAATCGTTCCGCACGCACCTCAAGGCACATCTCGAGCAGAGTGCGGCCAGTGCGGCGGCAGCCGCTGCAATGCGACTGTCTGGGGAGCATGCCAACTCGGGCACTTCCGGAGCATCATCATCCCTTTCGCTTACGACCTTCCTCTGTCAGCAGTGTGGTGTAACGTTGAGCTGTCAGGCGGATGGTAAGAGCACCTTCGGCAAGGTGGAGGACCTGCACAAACATCTGTACGAAGGGCATATGCAACTCCTCTACAAGTGTACGGTTTGTGGGGAGACGTTCGAATCCAAGGTTCAGGTGCAGGTACACTTTGCCGTGAGTCATTCAGTGGAGGTGAAGCTGTACCGCTGCTCAGCCTGTGCTGAAGTGTTCCGTTCGGAGCGTGATTTTAGGCAACACATTCGAAATCGCCACCTGACGGCAGGTGCCGTCCAGTGTATGTTCTGCCGGATGGTTTGCTCGTCCGAGCTTGAGATGCACTTCCATCTTGCGTCACACGCCAGGAAGTACAAATGTCCAGCCTGTCCAGAGTCGTTCCATGTGGAGTTTCTGCTCGATCGGCACATTCAAACGCACCACAGCCAGAAGGAGACGTCCTCACCGAACCGAGGCCGAGAGTCTGCCAACGGTGGCCACAACCTGTCAACTACATCCTCCTGCTCCACCAACTCAACGCCCTCAACGGCCACCGCAGTGTCGTCTACAGCTCAACCGACCTCAACAACAACAACCGTCACCGGGCTAGACTACCTTCACCTACACGGACAAATGGCGGCAATGGCAGCAGCTGCGGCTTGGCCCACCCTGTACCAAACGGCCGCCAACAAGTTCTACAGCAGCAACCCGCTGCAAGTGGACACACTCTCCCAGCTGAAGCATCCACAGCAACTACTGCACGGTTTCTACGACACCATGCTCGGTAAAGCGCAAGCACAACAGCAACAGCAGCAGCGTGGTGCATTCCTTCCCGAGTCATCCAGCGGCGGCAAGAAGAACCCCTTCGTTGCTGGCCATTCACCCAATGCCAGTGCGAACGCTACTGCTAATGCACTGCTTGGGCTAGGCTATGGAGGTGCATCACTTACTTCAGGAAACTCCCAACAGCCAAGAACTTCCACGCTTAATGGTTCCTCTTCTGGGCTTTACTCCCCCGAGGAAGGTCCTAATGGTGGGTCGAGTGTGGCCACTAGTAGCTCAAAGCTTTACTCTCCCATTGCCATGATACAGCGGTACGGTGATGGTGGTGTACTACATTCCACATCTGGTGCAGCGCCGCCTACTACTAGCGGTTGCCCTTCCCGCACGGAATCTCCTACACCGAGTGGGCAACAACTTCTTCTGGCAGCTCACTCCTCACTAAGTTCACTGCCTGAACATCATCCCGAACAGCAGCAGTCGAGTAATCGAAAAACAGCCCAACAGCAGTCAGGTCCTAAGACATCATCCGGTACAATCACACCACAGCTGATTGCACCCGGCTCGAACAGCTGCTACAGCTGCGGTATCTGCGAACGGTCCGACTTTAGCACGGAGAGTGAGGTCCAAACTCATCGCAAGATTGTGCACAACTTGAAAACGGGCGTTAGTTTGCGGTGTGCGTACTGCAACGGAGACTTCCGGTCGAGGAATGAGCTCGAGAACCACATGAAGGTCGCACACAATACGGGCGGTGGCAAGCACAAGTGTTTGATCTGTGACGAAATCTTCCCATCGCCGGCAGTACTTGCCGAGCATAAGCTGACGCACTGTAAGGTGGGTGCTTCGGGACGCTGTTCGCACTGCAGTTTGCCCCTGCCCGATGCTCACACCTTCAAGCAGCATCTGCCGGCTCATCAGCAGATCGGTGGATCATCTTCTGGATCGACAGGAGGAGGCACCACCTCATCGACGAATGGCTCCTCAAACGGAGGTACGTCTGGTGCGGGTAACTCCTCCACTGGACAGAGTGCGTCTTCTTCGGCCGGTGCAAATTCGAGTGGCACGGGAACAAGTTCCAACTCGAATGCGGATCAGGATCGCTTCCCTCAGCAGTGCATCTGTTGCCGACAAACGCTCAACTCTGAATTTGAAATTAGTCTTCATGCCAAATTCCACACCAAAACCGCGGAGACTAACGAGCGCACGTGTGCTCTCTGCCTGGAGCCGTTACCTTCACAACCCGAGTCCAACACCAAGATCTGTGATCCCTGTCTGAAACGGCACAATTTCCCATCGAAGCTCCTATCGATGAACTTCCTGAAGCCTGCCACCTCATCGCTAGTGCCAACACCAACCCACGGTGGATCATCTTCAGCCGGTGTTGTTGTACCACCAACTCACGGTACAACCATTGGTAACAGTGTCGCAGCAGAAGGAAGACCACCACTACCACCACCACCGCCAACATCCTCGGGAAGTCTTCAACAAGACCCACAACACCCGGGCGGCGTACGGGATGGTTCATCCTCTGCCCTGTTCCAGTGCAATCTGTGCAAGAAACCGTTACCCACCGCCCAAAAGCTCCAAGAACATCTGATCGATCATACGTTCGCGGGCTGTGAGGAGCGCGGCTACGTCTGCTACCTGTGCTCGGCCGTGTTTACCTCCTCGGCCGGACTGCAGACCCATCTGCCGCTGGCGCATTCTAACGCGGCCGCCAAACCGTACGACTGTGAGCGGTGCGGTGTGGCGTACTTCTTCCGGGCCGAGCTGGAGCACCATCTGATCGATCATGAGCTGGGCAAGGCGATAAGGCCCTCCTCCTTTGAGGTAGCTTCGTCCGATGAGTGGCACACAATGGTGCAGCAGCGTTCTCCGATGGGTGAGGATGATGGTGGTGGCCACACAGGCCACATCAAGCAGGAACAGTGTGAGCCTGAGCAGGAACAGGATGGATCATCATCACCGTATCATCACCAGAAAGATGAAGATTCTGATGATGGGAACGACTTCCAACAGGCTAGAAACGGAGAGGAAACAAATGAGGTGGATATGGAGCAGGAACAGGAGGACGAGGACAATGAACAGACTCACGCTGAGGAACGACAGGAAGAGCAGGAAGATGAAGAAGAGTACATTGAGGTAGAGCACACTACGCTGGATGATGGTGGACGAGGAGGCAAGCAAGCAAGCGACGAACGGCTGCGTCGAACATCGAACCTGTTGATCAATGGCGGGAAGGATTGCTCTGCGCTGACTGCTACCACGACGGCAACCACTCTTCCGGTTGTAACGGCTGCTGAGTGA
Protein Sequence: MFIQFGLQRSSAGANQTYTSSTIAIIIIIAESHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGGKRGAKFSPYSNDPLMLMSRGNSKLSSSLSKAASNRTPTPGSTAGGGGNAALGGLGSGAGGGTGTNHHQQDLLSCPYCTRTDFGTLEQLGLHVQSMHGHGGAGALGLLAGDSSMSYFTPAGGRRAVTPDGSNVPLSLGGLSPYPPISCEFCTMKFPTVPLMFAHLKTAHLDRLAGSGGGHQRSSPSNGTGSPLGSRPPSGFHPLDQLHFNKSLLGSAFPSFYGGGGGGGGSSNSLAGMSGGSIKAERRLMAERDENGNEEEAGGRKRQRRGDDGADVRGSMSKRDKQEKEEEQAIEGDEEDDEDDDNDVEGEDNEEGESEAHGANNRCEESVDYKEEAIDTKITPIKQERKEEPAEGEPSPSTSARSSPCGDSLELGSGRAGSHPSGRTSPAEQLTPTDLSQPKVKRLKLETPEEDSLTDGADRKRMMMTGSAASVRSQTTREQHKHRGPATTATATGRRDSEAKDSHLQHGSLMHSSTSSSNVQHSQQMGAPTSTGTSSQHHHQPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAASAAAAAAMRLSGEHANSGTSGASSSLSLTTFLCQQCGVTLSCQADGKSTFGKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACAEVFRSERDFRQHIRNRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHIQTHHSQKETSSPNRGRESANGGHNLSTTSSCSTNSTPSTATAVSSTAQPTSTTTTVTGLDYLHLHGQMAAMAAAAAWPTLYQTAANKFYSSNPLQVDTLSQLKHPQQLLHGFYDTMLGKAQAQQQQQQRGAFLPESSSGGKKNPFVAGHSPNASANATANALLGLGYGGASLTSGNSQQPRTSTLNGSSSGLYSPEEGPNGGSSVATSSSKLYSPIAMIQRYGDGGVLHSTSGAAPPTTSGCPSRTESPTPSGQQLLLAAHSSLSSLPEHHPEQQQSSNRKTAQQQSGPKTSSGTITPQLIAPGSNSCYSCGICERSDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCSLPLPDAHTFKQHLPAHQQIGGSSSGSTGGGTTSSTNGSSNGGTSGAGNSSTGQSASSSAGANSSGTGTSSNSNADQDRFPQQCICCRQTLNSEFEISLHAKFHTKTAETNERTCALCLEPLPSQPESNTKICDPCLKRHNFPSKLLSMNFLKPATSSLVPTPTHGGSSSAGVVVPPTHGTTIGNSVAAEGRPPLPPPPPTSSGSLQQDPQHPGGVRDGSSSALFQCNLCKKPLPTAQKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQTHLPLAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGKAIRPSSFEVASSDEWHTMVQQRSPMGEDDGGGHTGHIKQEQCEPEQEQDGSSSPYHHQKDEDSDDGNDFQQARNGEETNEVDMEQEQEDEDNEQTHAEERQEEQEDEEEYIEVEHTTLDDGGRGGKQASDERLRRTSNLLINGGKDCSALTATTTATTLPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104586; iTF_00101143; iTF_00093654; iTF_00107176;
90% Identity: iTF_00104586;
80% Identity: -