Basic Information

Insect: Anopheles fontenillei
Gene Symbol: L
Assembly: GCA_008817895.1
Location: VTWG01001773.1:17590-38128[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00045 0.025 14.7 3.6 1 23 178 200 178 200 0.97

2 18 0.67 38 4.7 5.7 1 23 206 228 206 228 0.98

3 18 5.6e-06 0.00031 20.7 3.7 1 23 234 256 234 256 0.99

4 18 1.7e-05 0.00095 19.2 0.3 1 23 262 284 262 284 0.98

5 18 7.3 4.1e+02 1.5 0.1 2 23 391 414 390 414 0.78

6 18 0.11 6.5 7.2 0.1 2 23 464 486 463 486 0.96

7 18 0.23 13 6.2 0.2 1 23 772 794 772 794 0.95

8 18 7.5 4.3e+02 1.4 0.6 1 23 832 854 832 854 0.90

9 18 0.00036 0.021 15.0 0.2 1 23 901 924 901 924 0.93

10 18 0.0041 0.23 11.7 0.7 1 23 931 954 931 954 0.97

11 18 0.0027 0.15 12.3 1.5 1 23 986 1008 986 1009 0.96

12 18 0.47 27 5.2 0.2 1 23 1318 1342 1318 1342 0.91

13 18 0.00067 0.038 14.2 0.2 2 23 1351 1373 1350 1373 0.96

14 18 0.0049 0.28 11.5 0.1 1 23 1380 1402 1380 1402 0.98

15 18 2.5 1.4e+02 2.9 1.2 2 20 1410 1428 1410 1431 0.94

16 18 0.0074 0.42 10.9 0.2 1 23 1637 1659 1637 1659 0.96

17 18 0.014 0.77 10.1 0.1 1 20 1669 1688 1669 1692 0.95

18 18 0.041 2.3 8.6 0.3 1 23 1700 1722 1700 1722 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00045	0.025	14.7	3.6	1	23	178	200	178	200	0.97
2	18	0.67	38	4.7	5.7	1	23	206	228	206	228	0.98
3	18	5.6e-06	0.00031	20.7	3.7	1	23	234	256	234	256	0.99
4	18	1.7e-05	0.00095	19.2	0.3	1	23	262	284	262	284	0.98
5	18	7.3	4.1e+02	1.5	0.1	2	23	391	414	390	414	0.78
6	18	0.11	6.5	7.2	0.1	2	23	464	486	463	486	0.96
7	18	0.23	13	6.2	0.2	1	23	772	794	772	794	0.95
8	18	7.5	4.3e+02	1.4	0.6	1	23	832	854	832	854	0.90
9	18	0.00036	0.021	15.0	0.2	1	23	901	924	901	924	0.93
10	18	0.0041	0.23	11.7	0.7	1	23	931	954	931	954	0.97
11	18	0.0027	0.15	12.3	1.5	1	23	986	1008	986	1009	0.96
12	18	0.47	27	5.2	0.2	1	23	1318	1342	1318	1342	0.91
13	18	0.00067	0.038	14.2	0.2	2	23	1351	1373	1350	1373	0.96
14	18	0.0049	0.28	11.5	0.1	1	23	1380	1402	1380	1402	0.98
15	18	2.5	1.4e+02	2.9	1.2	2	20	1410	1428	1410	1431	0.94
16	18	0.0074	0.42	10.9	0.2	1	23	1637	1659	1637	1659	0.96
17	18	0.014	0.77	10.1	0.1	1	20	1669	1688	1669	1692	0.95
18	18	0.041	2.3	8.6	0.3	1	23	1700	1722	1700	1722	0.95

Sequence Information

Coding Sequence: ATGGCGCTGAAGATGCTCTACCGTGGCCCGAGCACCAGACTGGAAACGTTGATCGAGAAGATACAGCAAAACACGAACGCTTTCGGTGTCGGCGGCATGATTGCGCCCGGTGCACTGGGTGGTGGTATCGGTGCGATGAAGGAGTTTTCCCTCGGACAAGAGCTATACTCGTCCCACACCTCGTCCAGCTTTTCGCCCTCGATTTCGGACGGCATGACAACGCCCAACTCGATCCCCGAGCCAAACGATGGGCCAACAACCGCGCTCGATTCGGGCGCCGCCGGTGAAAAGCAGTACCGGAACCATCACCCGCATCATCAGCTGCACCCGCGGCATGTGCATCATCTGCATCATCGCCGGGCCGGTGGCATCGGTGGACATTCTTCGACCGGCGGCAAGGAAGGTGGTGGCAAGTCGTCCTCAAAACACCATCAAcagcataacaacaacaacaacagtagtAACCACCACAatcacaacaataacaacaacggcaaggggctgggtggtggtggtgccggcagcagcacctaCCATTGCCAGTTCTGCGAGAAAACGTTCCCGCGGCTCGGCTATCTGAAGAAGCACGAACAGAGCCACACCGAGCATATGCCATTCAAATGTGAGTACTGTGCCCGACTGTTCAAGCACAAACGATCGCGGGATCGCCATACGAAGCTGCATACCGGCGATCGACGCTATCGCTGTCTGCACTGCGAGGCTGCATTCTCCCGAAGTGATCATCTGAAGATACACATGAAAACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGAGGCTACAATACGGCCGCAGCGCTAACGAGCCATATGCAAAATCACAAGAAGCAGCTGGCGTTGACCGGGAGTCCCAACCTTACGTACAGTCCACGCTCCACCACAAGCTCCCTCTCGAGTGGAGGAggaagtggtggtggcggtggtaaGCGAGGGTCAAAGTTCTCGCCCTACTCCAACGACCCACTGATGCTGATGAGCCGCGGCAACTCCAAACTGTCCTCGTCCCTTTCCAAAGCCGCAAGTAATCGAACTCCAACACCTGGGAGTAcggccggcggtggtggcaacGCAACTCTGGGAGGTGTGGGAAGTGGTGCGGGAGTTGGTACCGGCTccaaccatcatcagcagGATCTGCTCTCCTGTCCGTACTGTACGCGGACGGATTTTGGGACGCTCGAACAGCTCGGCCTCCATGTGCAGTCGATGCACGGgcatggtggtgctggtgcattGGGATTGCTTGCTGGCGACTCCTCAATGTCTTACTTCACACCTGCCGGTGGACGACGTGCAGTGACACCCGATGGGAGCAACGTCCCGCTCTCACTCGGTGGTCTCAGTCCGTACCCGCCGATTAGCTGCGAGTTCTGCACGATGAAGTTCCCAACCGTTCCGCTCATGTTTGCCCATCTCAAGACGGCTCATCTGGATCGGTTGGCTGGCAGTGGTGGACATCAACGAAGCTCACCATCGAATGGTACCGGCAGTCCGCTCGGGTCACGCCCTCCCAGTGGGTTCCACCCGCTAGACCAGCTGCACTTTAACAAGAGTCTGCTTGGGAGtgctttcccttccttctatggtggtggtgggggttcTTCCAACAGCCTTGCCGGAATGTCCGGAGGCAGTATTAAAGCGGAGCGCCGACTAATGGTCGATCgtgatgaaaatggaaatgaagaagaagcgGGAGGTAGAAAGCGGCAGCGCAGAGGCGACGATGGAGAAGATGTTAAGGGGAGCATGTCGAAACGGGACAAGCAGGAAAGGGAGGAGGAACATGCTATTGAAGGTGATGAGGAGGACGATGcggatgatgataatgatgttgAGGGAGACGATAATGAGGAGGGAGAAAGTGAGGCTCATGGAGCGAACAATCGAAGTGAGGAGTCCGTTGACTACAAGGAAGAAGCGATCGATACGAAGATCACACCGATCAAGCAGGAGCGAAAGGAAGAGCCTGCTGAGGGTGAGCTATCTCCTTCGACATCTGCACGATCGTCTCCTTGTGGTGATTCACTGGAATTGGGAAGTGGACGTCCTGGAAGTCATCCATCGGGACGTACAAGTCCAGCAGAGCAACTCACACCAACAGACCTGAGTCAGCCGAAGATGAAGCGTCTCAAGCTGGAGACGCCCGAAGAAGACCCAGTGACCGACGGGGCGGATAGgaagaggatgatgatgacagcTAACGTTCAACACGCCCAGCAGATGGGTGCACCTACTTCTACCGGATCATCAtcccagcaccaccatcaacctCCCGGCGCATACCTCTGCAATCAGTGCAATGCAGCACTGCCCGATTTCGAATCGTTCCGCACGCACCTCAAGGCACATCTCGAGCAGAGTGCGGCCAGTGCGGCAGCAGCCGCTGCCATGCGACTGTCTGGGGAGCATGTCAACTCGGGCAGTTCCGGGGGCAGTTCATCATCTCTTTCGCTTACGACCTTCCTCTGTCAGCAGTGTGGTGTTACGTTGAGCTGTCAGGCGGAGTACGAACAGCACACGATTGGCCATTTCCTTGTGACGGCGGTCGAGTATCGATGTCAGGGGTCGACCGGAACTGCAGGCCCTGCTAGCTGCAGCGGTAAGAGCACCTTCGGCAAGGTGGAGGACCTTCACAAACATCTGTACGAAGGGCATATGCAACTCCTCTACAAGTGTACGGTTTGTGGGGAGACGTTCGAATCCAAGGTTCAGGTGCAGGTACACTTTGCCGTGAGTCATTCGGTCGAGGTGAAGCTGTACCGCTGCTCAGCCTGTGCTGAAGCGTTCCGTTCGGAGCGTGATTTTAGGCAACACATTCGAAATCGCCACCTGACGGCGGGTGCCGTCCAGTGTATGTTCTGCCGGATGGTTTGCTCGTCCGAGCTTGAGATGCACTTCCATCTTGCGTCGCACGCCAGGAAGTACAAATGTCCAGCCTGTCCAGAGTCGTTCCATGTGGAgttcctgctcgatcggcatATTCAAACGCACCACAGCCAAAAGGAGACGTCCTCACCGAACCGAGGCCGAGAGTCCGCCAACGGTGGCCACAACCTGTCAACTACATCTTCCTGCTCCACCAACTCCACGCCCTCAACGGCCACAGCAGTGTCGTCTACAGCTCAACCGacctcaacaacaacaaccgtcaCGGGGTTGGACTACCTGCACCTCCACGGACAGATGGCGGCAATGGCAGCAGCTGCGGCTTGGCCCACCCTGTACCAAACTGCTGCCAACAAGTTCTACAGTAGCAACCCGCTGCAAGTAGACACACTGTCCCAGCTGAAGCATCCACAGCAGCTTCTGCACGGTTTCTACGACACCATGCTCGGTAAAGCGCaagcgcaacagcagcagcagcagcatcgtggTGCATTCCTTCCCGAGCCATCCAGCGGTGGCAAGAAGAACCCCTTCGTTGCTGGCCATTCACCCAATGCCAGCGCGAACGCTACTAATGCACTGCTTGGGCTAGGCTATGGAGGTGCATCACTTACTTCAGGAAACTCCGCGCAGCAAAGAACTTCCACGCTTAATGGTTCCTCTTCTGGGCTTTACTCCCCCGAGGAAGGTCCTAATGGTGGGTCGAGTGTGGCCACTAGTAGCTCAAAGCTTTACTCTCCCATTGCCATGATACAGCGGTACGGTGATGGTGCTGCCGGTGTTGCGGCACTACATTCCACACCTGGTACAGCGCCGCCTACTGCTACCGGATGTCCTTCCCGCACGGAATCTCCTACACCGAGTGGACAGCAACTTCTTCTGGCAGCTCACTCCTCGCTAACTTCACTGCCTGAACATCATcccgaacagcagcagtcgaGTAATCGAAAGACAGCCCAACCGCAGTCGGGTCCTAAGACATCATCCGGTACAATCACACCACAGCTGATTGCACCCGGCTCGAACAGCTGCTACAGCTGCGGCATCTGCGAACGGTCCGACTTTAGCACGGAGAGTGAGGTCCAAACGCATCGCAAGATTGTGCACAACTTGAAAACGGGCGTTAGTTTGCGGTGTGCGTACTGCAACGGGGACTTCCGGTCGAGGAACGAACTGGAGAATCACATGAAGGTCGCACACAATACGGGCGGTGGCAAGCACAAGTGTTTGATCTGTGACGAAATCTTCCCATCGCCGGCAGTACTAGCCGAACATAAGCTGACCCACTGTAAGGTGGGTGCATCGGGTCGCTGTTCGCACTGTAGTTTGCCCCTGCCCGATGCTCACACCTTCAAGCAGCATCTGCCGGCTCATCAGCAGATCGGTGGATCATCCTCGGGAACGACAGGAGGAGGCACCACCACATCGACGAATGGCTCCTCAAACGGAGGTACGTGTGGTAACTCCTCCACTGGACAGAGTGCGTCTTCTTCGGCCGGAGCTAATTCGAGTGGCACGGGGACAAGTTCCAACTCGAATGCGGATCAGGATCGCTTCCCTCAGCAGTGCATCTGTTGCCGACAAACGCTCAACTCCGAGTTTGAAATTAGTCTTCATGCCAAATTCCACACCAAAACCGCGGAGACTAACGAGCGCACGTGTGCTCTCTGCCTGGAGCCGTTACCTTCGCAACCCGAGTCCAACACCAAGATCTGTGATCCCTGTCTGAAACGGCACAATTTCCCTACGAAGCTCCTATCGATGAACTTCCTGAAGCCTGCCACCTCAGCTCTAGTGCCAACACCAACCCACGGTGGATCATCTTCAGCCGGTGTTGTTGTACCACACACTCACGGTACAACCATTGGTAACAGTGTCGCAGTTGAAGGAagaccaccactaccaccaccgccgccaacaTCCTCGGGAAGTCTTCAACAAGACCCACAACACCCGGGCGTCGGACGGGAAGGTTCATCCTCTGCACTGTTTCAGTGCAATCTGTGCAAGAAACCGTTACCCTCCGCCCAAAAGCTCCAGGAACATCTGATCGATCATACGTTCGCGGGCTGTGAGGAGCGCGGCTACGTCTGCTACCTGTGCTCGGCCGTGTTTACCTCTTCGGCCGGACTGCAGACCCATCTGCCGCTGGCACACTCTAACGCGGCCGCCAAACCGTACGACTGTGAGCGGTGCGGTGTGGCTTACTTCTTCCGGGCCGAGCTGGAGCACCATCTGATCGATCATGAGCTGGGCAAGGCGATAAGGCCCTCCTCCTTTGAGCTAGCTTCGTCCGATGAGTGGCACACAATGGTGCAGCAGCGTTCTCCGATGGGTGAGGATGATGGCGGTGGCCACACAGGCCACATCAAGCAGGAACAGTGTGAGCCTGAGCAGGAACAGGAtggatcatcatcaccgtaTCATCACCAGAAAGATGAAGATTCTGATGATGGGAACGGCTTCCAACAGTCTAGAAACGGagaagaggcgaatgaggtgGATATGGAGCAGGAACAGGAGGACGAGGACAATGAACAGACTCACGCTGAGCAAGAGCAGGAAGATGATGAAGAATACATTGAGGTAGAGCACACTACGCTGGATGATGGTGGACGAGgaggcaagcaagcaagcgacgaacggctCCGTCGACCGTCGAACCTGTTGATCAATGGCGGGAAGGATTGCTCTGCGCTGACTGCTACCACGACGGCAACTACTCTTCCGGTTGTAACGGCTGCTGAGTGA
Protein Sequence: MALKMLYRGPSTRLETLIEKIQQNTNAFGVGGMIAPGALGGGIGAMKEFSLGQELYSSHTSSSFSPSISDGMTTPNSIPEPNDGPTTALDSGAAGEKQYRNHHPHHQLHPRHVHHLHHRRAGGIGGHSSTGGKEGGGKSSSKHHQQHNNNNNSSNHHNHNNNNNGKGLGGGGAGSSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGGGKRGSKFSPYSNDPLMLMSRGNSKLSSSLSKAASNRTPTPGSTAGGGGNATLGGVGSGAGVGTGSNHHQQDLLSCPYCTRTDFGTLEQLGLHVQSMHGHGGAGALGLLAGDSSMSYFTPAGGRRAVTPDGSNVPLSLGGLSPYPPISCEFCTMKFPTVPLMFAHLKTAHLDRLAGSGGHQRSSPSNGTGSPLGSRPPSGFHPLDQLHFNKSLLGSAFPSFYGGGGGSSNSLAGMSGGSIKAERRLMVDRDENGNEEEAGGRKRQRRGDDGEDVKGSMSKRDKQEREEEHAIEGDEEDDADDDNDVEGDDNEEGESEAHGANNRSEESVDYKEEAIDTKITPIKQERKEEPAEGELSPSTSARSSPCGDSLELGSGRPGSHPSGRTSPAEQLTPTDLSQPKMKRLKLETPEEDPVTDGADRKRMMMTANVQHAQQMGAPTSTGSSSQHHHQPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAASAAAAAAMRLSGEHVNSGSSGGSSSSLSLTTFLCQQCGVTLSCQAEYEQHTIGHFLVTAVEYRCQGSTGTAGPASCSGKSTFGKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACAEAFRSERDFRQHIRNRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHIQTHHSQKETSSPNRGRESANGGHNLSTTSSCSTNSTPSTATAVSSTAQPTSTTTTVTGLDYLHLHGQMAAMAAAAAWPTLYQTAANKFYSSNPLQVDTLSQLKHPQQLLHGFYDTMLGKAQAQQQQQQHRGAFLPEPSSGGKKNPFVAGHSPNASANATNALLGLGYGGASLTSGNSAQQRTSTLNGSSSGLYSPEEGPNGGSSVATSSSKLYSPIAMIQRYGDGAAGVAALHSTPGTAPPTATGCPSRTESPTPSGQQLLLAAHSSLTSLPEHHPEQQQSSNRKTAQPQSGPKTSSGTITPQLIAPGSNSCYSCGICERSDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCSLPLPDAHTFKQHLPAHQQIGGSSSGTTGGGTTTSTNGSSNGGTCGNSSTGQSASSSAGANSSGTGTSSNSNADQDRFPQQCICCRQTLNSEFEISLHAKFHTKTAETNERTCALCLEPLPSQPESNTKICDPCLKRHNFPTKLLSMNFLKPATSALVPTPTHGGSSSAGVVVPHTHGTTIGNSVAVEGRPPLPPPPPTSSGSLQQDPQHPGVGREGSSSALFQCNLCKKPLPSAQKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQTHLPLAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGKAIRPSSFELASSDEWHTMVQQRSPMGEDDGGGHTGHIKQEQCEPEQEQDGSSSPYHHQKDEDSDDGNGFQQSRNGEEANEVDMEQEQEDEDNEQTHAEQEQEDDEEYIEVEHTTLDDGGRGGKQASDERLRRPSNLLINGGKDCSALTATTTATTLPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095829;
90% Identity: iTF_00104586;
80% Identity: -