Basic Information

Insect: Anopheles arabiensis
Gene Symbol: L
Assembly: GCA_016920715.1
Location: NC:70339876-70409697[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0005 0.024 14.6 3.6 1 23 329 351 329 351 0.97

2 18 0.76 36 4.6 5.7 1 23 357 379 357 379 0.98

3 18 6.3e-06 0.0003 20.5 3.7 1 23 385 407 385 407 0.99

4 18 1.9e-05 0.00091 19.0 0.3 1 23 413 435 413 435 0.98

5 18 8.2 3.9e+02 1.3 0.1 2 23 541 564 540 564 0.78

6 18 0.13 6.2 7.0 0.1 2 23 614 636 613 636 0.96

7 18 0.26 13 6.0 0.2 1 23 975 997 975 997 0.95

8 18 8.5 4.1e+02 1.3 0.6 1 23 1034 1056 1034 1056 0.90

9 18 0.00041 0.02 14.8 0.2 1 23 1103 1126 1103 1126 0.93

10 18 0.003 0.14 12.1 0.8 1 23 1133 1156 1133 1156 0.97

11 18 0.0031 0.15 12.1 1.5 1 23 1188 1210 1188 1211 0.96

12 18 0.53 25 5.0 0.2 1 23 1515 1539 1515 1539 0.91

13 18 0.00076 0.036 14.0 0.2 2 23 1548 1570 1547 1570 0.96

14 18 0.0056 0.27 11.3 0.1 1 23 1577 1599 1577 1599 0.98

15 18 2.9 1.4e+02 2.7 1.2 2 20 1607 1625 1607 1628 0.94

16 18 0.0059 0.28 11.2 0.2 1 23 1835 1857 1835 1857 0.96

17 18 0.015 0.74 9.9 0.1 1 20 1867 1886 1867 1890 0.95

18 18 0.046 2.2 8.4 0.3 1 23 1898 1920 1898 1920 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0005	0.024	14.6	3.6	1	23	329	351	329	351	0.97
2	18	0.76	36	4.6	5.7	1	23	357	379	357	379	0.98
3	18	6.3e-06	0.0003	20.5	3.7	1	23	385	407	385	407	0.99
4	18	1.9e-05	0.00091	19.0	0.3	1	23	413	435	413	435	0.98
5	18	8.2	3.9e+02	1.3	0.1	2	23	541	564	540	564	0.78
6	18	0.13	6.2	7.0	0.1	2	23	614	636	613	636	0.96
7	18	0.26	13	6.0	0.2	1	23	975	997	975	997	0.95
8	18	8.5	4.1e+02	1.3	0.6	1	23	1034	1056	1034	1056	0.90
9	18	0.00041	0.02	14.8	0.2	1	23	1103	1126	1103	1126	0.93
10	18	0.003	0.14	12.1	0.8	1	23	1133	1156	1133	1156	0.97
11	18	0.0031	0.15	12.1	1.5	1	23	1188	1210	1188	1211	0.96
12	18	0.53	25	5.0	0.2	1	23	1515	1539	1515	1539	0.91
13	18	0.00076	0.036	14.0	0.2	2	23	1548	1570	1547	1570	0.96
14	18	0.0056	0.27	11.3	0.1	1	23	1577	1599	1577	1599	0.98
15	18	2.9	1.4e+02	2.7	1.2	2	20	1607	1625	1607	1628	0.94
16	18	0.0059	0.28	11.2	0.2	1	23	1835	1857	1835	1857	0.96
17	18	0.015	0.74	9.9	0.1	1	20	1867	1886	1867	1890	0.95
18	18	0.046	2.2	8.4	0.3	1	23	1898	1920	1898	1920	0.95

Sequence Information

Coding Sequence: ATGAAAGGTGACAGCATGCTAGAGGACAttaccgatgatgatgagcgtGCTGGTGAGGAGCAAGACTTGGAGGATACAAGTGATGATGAGCCTGAGATGGAGGTGAAGCCTAAGGATGCGAAAGAGGGAAGTGTTACCCGGTGCAAGGATatgaaaagtgtgtgtgagttggcAGTGAACCCGTGTGAAGGAAGGTCGAGTGTTGGCGCTAATGTCGCTACTTCCAATGACATCCAAGAGGAGGATGAGTTGTGCGCGGATGTGGGAAAAAGTGACTATGTTGGGAATAGCAGCACAGTTCAGGAGAATCGGAAAGCTAGTGAGACAAACCAACCTCAACTAGCCGCTGATGATACATCAGTGCATTCTGGACATTCTGCTGGACATCAAGCAATAGCAGAAGAAGTGGAAGACAACGAGGAAGAACATGAGGAAATCGATGATGAAGCTGTTAATAATGAAGAtgacgatgaagatgatgatgagattgatgatgacgatgatgatgtagATGACGAGTCACTTGGAGATGACGAAGAGGGTGAAGCTGGTCCTAGACATTTTGGCGGGGACGACCAAgatgttgatgatgagttCACATCGGATAGCTTTTGTTCAGAGCTATACTCGTCCCACACTTCGTCCAGCTTTTCGCCCTCAATTTCGGACGGCATGACAACGCCCAACTCGATACCCGAGCCAAACGATGGGCCAACTACGCTCGATTCGGGCGCCGCCGGTGAAAAGCAGTACCGGAACCATCACCCGCATCATCAGCTGCACCCGCGGCATGTGCATCATCTGCATCATCGCCGGGCCGGTGGTATCGGTGGACATTCTTCGACCGGTGGCAAGGAAGGTGGTGGCAAGTCGTCCTCGAAACACCATCAACAgcataataacaacaacaacaacagtagtAACCACCACAatcacaacaataacaacggCAAGGGCCTGGGTGGGGgtgccggcagcagcacctACCATTGCCAATTCTGCGAGAAAACGTTCCCGCGGCTTGGCTATCTGAAGAAGCACGAACAGAGCCACACGGAGCATATGCCATTCAAATGTGAGTACTGTGCCCGACTGTTCAAGCACAAACGATCGCGGGATCGCCATACGAAGCTGCATACCGGCGATCGACGCTATCGCTGTCTGCACTGTGAGGCTGCATTCTCCCGAAGTGATCATCTGAAGATACACATGAAAACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGAGGCTACAATACGGCCGCAGCGCTAACGAGCCATATGCAAAATCACAAGAAGCAGCTGGCCCTGACCGGGAGTCCCAACCTTACGTACAGCCCACGCTCCACCACAAGCTCCCTGTCGAGTGGAGGaggaagtggtggtggtggtaagcGAGGGGCAAAGTTCTCGCCCTACTCCAACGACCCACTGATGCTGATGAGCCGCGGCAACTCCAAACTGTCCTCGTCCCTTTCCAAAGCCGCAAGTAATCGAACTCCAACGCCTGGGAGTAcggccggcggtggtggcaacGCAACTCTGGGAGGTCTGGGAAGTGGTGCGGGAGGTGGTACCGGCACCAGCCATCATCAGCAGGATCTGCTCTCCTGTCCGTACTGTACGCGGACGGATTTTGGGACGCTCGAACAGCTCGGGCTCCATGTGCAGTCGATGCACGGgcatggtggtgctggtgcattGGGATTGCTTGCTGGCGACTCCTCAATGTCTTACTTCACACCTGCCGGTGGACGACGTGCAGTGACACCCGATGGGAGCAACGTCCCGCTCTCACTCGGTGGTCTCAGTCCGTATCCACCGATTAGCTGCGAGTTCTGCACGATGAAGTTCCCAACCGTTCCGCTCATGTTTGCCCATCTCAAGACGGCTCATCTGGATCGGTTGgctggcagtggtggtggtcatCAACGAAGCTCACCATCGAATGGTACCGGCAGTCCGCTCGGGTCACGTCCTCCCAGTGGGTTCCATCCGCTAGACCAGCTGCACTTTAACAAGAGCCTGCTTGGGAGTGCTTTCCCCTCCTTctacggtggtggtggtggtggttcttGCAACAGCCTGGCCGGAATGTCCGGAGGCAGTATTAAAGCGGAGCGCCGGCTAATGGCCGAACgtgatgaaaatggaaatgaagaagaagcggGAGGTAGAAAGCGGCAGCGCAGAGGAGACGATGGAGCAGATGTTAGGGTGAGCATGTCGAAACGGGACAagcaggaaaaggaggaggaacAAGCAATTGAAGGTGATGAGGAggacgatgaggatgatgataatgacgtTGAGGGAGAAGATAATGAGGAGGGAGAAAGTGAGGCCCATGGAGCAAACAATCGATGTGAGGAGTCCGTTGACTACAAGGAAGAAGCGATCGATACGAAGATCACTCCGATCAAGCAGGAGCGAAAGGAAGAGCCTGCTGAGGGTGAGCCATCTCCTTCGACTTCTGCACGATCGTCTCCCTGTGGTGATTCCCTGGAGTTGAGAAGTGGACGTCCCGGAAGTCACCCATCGGGACGTACAAGTCCAGCAGAGCAACTCACTCCAACAGACCTGAGTCAGCCGAAGGTGAAGCGTCTCAAGCTGGAGACGCCCGAAGAAGACTCACTGACCGACGGGGCGGATAGGAAGAGGATGTTGATGACAGGGTCAGCAGCATCTGGAAGATCTCAAACAACTCGCGAGCAACACAAACATCGTGGTCCAGTAACAACCGCAACTGCAACAGGTCGTCGAGATAGTGAAGCGAAAGACTCACACCTCCAGCACGGCTCACTAATGCACTCCTCCTCTTCGAGCAACAACGTCCAACACGCCCAGCAGATGGGTGCTCCTACTTCTACCGGAACATCAtcccagcaccaccatcaaccTCCCGGCGCATACCTCTGCAATCAATGTAATGCCGCACTGCCCGATTTCGAATCGTTCCGTACGCACCTAAAGGCGCATCTCGAGCAGAGTGCAGCCAGTGCGGCGGCTGCCGCTGCCATGCGACTGTCTGGGGAGCATGCCAACTCGGGCAGTTCCGGTGCATCATCATCTCTTTCACTTACGACTTTCCTGTGTCAGCAGTGCGGTGTAACGTTGAGCTGTCAAGCGGAGTACGAACAGCACACGATTGGCCATTTCCTTGTGATGACGGTCGAGTATCGATGTCAGGGGTCGACCAGTACTGCAGGCCCTGCTAGCTGCAGTGGAAAGAGCACCTTCGGCAAGGTGGAGGACCTGCACAAACATCTGTACGAAGGGCATATGCAACTCCTCTACAAGTGTACGGTTTGTGGGGAGACTTTCGAATCCAAGGTTCAGGTGCAGGTACACTTTGCAGTGAGTCATTCAGTGGAGGTGAAGCTGTACCGTTGCTCAGCCTGTGCTGAAGTGTTCCGTTCGGAGCGTGATTTTAGGCAACACATTCGAAATCGCCACCTGACGGCAGGTGCCGTCCAGTGTATGTTCTGCCGGATGGTTTGCTCGTCCGAGCTTGAGATGCACTTCCATCTTGCGTCACACGCCAGGAAGTACAAATGTCCAGCCTGTCCAGAGTCGTTTCATGTGGAGTTTCTGCTCGATCGGCACATTCAAACGCACCATAGCCAGAAGGAGACGTCCTCACCGAACCGAGGCCGAGAGTCCGCCAACGGTGGCCACAACCTGTCAACTACATCATCCTGCTCCACCAACTCAACGCCCTCAACGGCCACCGCAGTGTCGTCTACAGCTCAACCGACCTCAACAACAACCGTCACCGGGCTAGACTACCTTCACCTACACGGACAAATGGCGGCAATGGCAGCAGCTGCGGCTTGGCCCACCCTGTACCAAACGGCCGCCAACAAGTTCTACAGCAGCAACCCGCTGCAAGTGGACACACTATCTCAGCTGAAACATCCACAGCAAATACTGCACGGTTTCTACGACACCATGCTCGGTAaagcgcaacagcagcagcaacagcagcagcgtggtGCATTCCTTCCCGAGCCATCCAGCGGCGGCAAGAAGAACCCCTTCGTTGCTGGCCATTCACCCAATGCCAGTGCGAACGCTACTGCTAATGCACTGCTTGGGCTAGGCTATGGAGGTGCAGCACTTACTTCAGGAAACTCCCAACAGCCAAGAACTTCCACGCTTAATGGTTCTTCTTCTGGGCTTTACTCCCCCGAGGAAGGTCCTAATGGTGGGTCGAGTGTGGCCACTAGTAGCTCAAAGCTTTACTCTCCCATTGCCATGATACAGCGGtacggtgatggtggtgtacTACATTCCACATCTGGTGCAGCGCCGCCTACTACTGGCGGTTGCCCTTCCCGCACGGAATCTCCTACACCGAGTGGGCAGCAACTTCTTTTGGCAGCTCACTCCTCGCTAACTACACTGCCTGAACATCATCCCGAACAGCAGCAGTCAAGTAATCGAAAGACAGCCCAACAGCAGTCAGGTCCTAAGACATCATCCGGTACAATCACACCACAGCTGATTGCACCCGGCTCGAACAGCTGCTACAGCTGCGGTATCTGCGAACGGTCCGACTTTAGCACGGAGAGTGAGGTCCAAACGCATCGCAAGATTGTGCACAACTTGAAAACGGGCGTTAGTTTGCGGTGTGCGTACTGCAACGGAGACTTCCGGTCGAGGAATGAGCTCGAGAACCACATGAAGGTCGCACACAATACGGGCGGTGGCAAGCACAAGTGTTTGATCTGTGACGAAATCTTCCCATCGCCGGCAGTACTTGCCGAGCATAAGCTGACGCACTGTAAGGTGGGTGCTTCCGGACGCTGTTCGCACTGCAGTTTGCCCCTGCCCGATGCTCACACCTTCAAGCAGCATCTGCCGGCTCATCAGCAGATCGGTGGATCATCTGCTGGATCGACAGGAGGAGGCACCACCACGAATGGCTCCTCAAACGGAGGTACATCTGGTGCGGGTAACTCCTCCACTGGACAGAGTGCGTCTTCTTCGGCCGGTGCAAATTCGAGTGGCACGGGAACAAGTTCCAACTCGAATGCGGATCAGGATCGCTTCCCTCAGCAGTGCATCTGTTGCCGACAAACGCTCAACTCTGAGTTTGAAATTAGTCTTCATGCCAAATTCCACACCAAAACCGCGGAGACTAACGAACGCACGTGTGCTCTCTGCCTGGAACCGTTACCTTCACAACCCGAGTCCAACAACACCAAGATATGTGATCCTTGTCTGAAACGGCACAATTTCCCAACGAAGCTCCTATCGATGAACTTCCTGAAGCCTGCCACCCCATCTCTGGTGCCAACACCAAACCACGGTGGATCATCTTCAGCCGGTGTTGTTGTACCACCAACTCACGGTACAACCATTGGTAACAGCGTCGCAGTAGAAGGAagaccaccactaccaccaccgccgccaacaTCCTCGGGAAGTCTTCAACAAGACTCACAACACCCGGGCGGCGTACGGGAAGGTTCATCCTCTGCCCTGTTCCAGTGCAATTTGTGCAAGAAACCGTTACCCACCGCCCAAAAGCTCCAAGAACATCTGATCGATCATACGTTCGCGGGCTGTGAGGAGCGCGGCTACGTCTGCTACCTGTGCTCGGCCGTGTTTACCTCCTCGGCCGGACTGCAGACCCATCTGCCGCTGGCACATTCTAACGCGGCCGCCAAACCGTACGACTGTGAGCGGTGCGGTGTGGCGTACTTCTTCCGGGCCGAGCTGGAGCACCATCTGATCGATCATGAGCTGGGCAAGGCGATAAGGCCCTCCTCCTTTGAGGTAGCTTCGTCCGATGAGTGGCACACAATGGTGCAGCAGCGTTCTCCGTTGGGTgaggatgatggtggtggccacACAGGCCACATCAAGCAGGAACAGTGTGAGCCTGAGCAGGAACAGGAtggatcatcatcaccgtATCACCACCAGAAAGATGAAGATTCTGATGATGGGAACGACTTCCAACAGGCTAGAAACGGAGAGGAAACGAATGAGGTAGATATGGAGCAGGAACAGGAGGACGAGGACAATGAACAGACTCACGCTGAGGTTAACAATGGAGGACAACGGGACGACGAGGATGATGGTCGTGATGATGCAGCAGTAGGCACTGAAGAGTGTAACGATGCagccgacgacgatgatgacgacgatgatgatgacgtagAAGATGAGGAGCACCAGGAACGACAGGAAGAGcaggaagatgaagaagagtACATTGAGGTAGAGCACACTACGCTGGATGATGGTGGACGAGgaggcaagcaagcaagcgacgaacggcTCCGTCGAACATCGAACCTGTTGATCAATGGCGGGAAGGATTGCTCTGCGCTGACTGCTACCACGACGGCAACCACTCTTCCGGTTGTAACGGCTGCTGAGTGA
Protein Sequence: MKGDSMLEDITDDDERAGEEQDLEDTSDDEPEMEVKPKDAKEGSVTRCKDMKSVCELAVNPCEGRSSVGANVATSNDIQEEDELCADVGKSDYVGNSSTVQENRKASETNQPQLAADDTSVHSGHSAGHQAIAEEVEDNEEEHEEIDDEAVNNEDDDEDDDEIDDDDDDVDDESLGDDEEGEAGPRHFGGDDQDVDDEFTSDSFCSELYSSHTSSSFSPSISDGMTTPNSIPEPNDGPTTLDSGAAGEKQYRNHHPHHQLHPRHVHHLHHRRAGGIGGHSSTGGKEGGGKSSSKHHQQHNNNNNNSSNHHNHNNNNGKGLGGGAGSSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGGKRGAKFSPYSNDPLMLMSRGNSKLSSSLSKAASNRTPTPGSTAGGGGNATLGGLGSGAGGGTGTSHHQQDLLSCPYCTRTDFGTLEQLGLHVQSMHGHGGAGALGLLAGDSSMSYFTPAGGRRAVTPDGSNVPLSLGGLSPYPPISCEFCTMKFPTVPLMFAHLKTAHLDRLAGSGGGHQRSSPSNGTGSPLGSRPPSGFHPLDQLHFNKSLLGSAFPSFYGGGGGGSCNSLAGMSGGSIKAERRLMAERDENGNEEEAGGRKRQRRGDDGADVRVSMSKRDKQEKEEEQAIEGDEEDDEDDDNDVEGEDNEEGESEAHGANNRCEESVDYKEEAIDTKITPIKQERKEEPAEGEPSPSTSARSSPCGDSLELRSGRPGSHPSGRTSPAEQLTPTDLSQPKVKRLKLETPEEDSLTDGADRKRMLMTGSAASGRSQTTREQHKHRGPVTTATATGRRDSEAKDSHLQHGSLMHSSSSSNNVQHAQQMGAPTSTGTSSQHHHQPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAASAAAAAAMRLSGEHANSGSSGASSSLSLTTFLCQQCGVTLSCQAEYEQHTIGHFLVMTVEYRCQGSTSTAGPASCSGKSTFGKVEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACAEVFRSERDFRQHIRNRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHIQTHHSQKETSSPNRGRESANGGHNLSTTSSCSTNSTPSTATAVSSTAQPTSTTTVTGLDYLHLHGQMAAMAAAAAWPTLYQTAANKFYSSNPLQVDTLSQLKHPQQILHGFYDTMLGKAQQQQQQQQRGAFLPEPSSGGKKNPFVAGHSPNASANATANALLGLGYGGAALTSGNSQQPRTSTLNGSSSGLYSPEEGPNGGSSVATSSSKLYSPIAMIQRYGDGGVLHSTSGAAPPTTGGCPSRTESPTPSGQQLLLAAHSSLTTLPEHHPEQQQSSNRKTAQQQSGPKTSSGTITPQLIAPGSNSCYSCGICERSDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCSLPLPDAHTFKQHLPAHQQIGGSSAGSTGGGTTTNGSSNGGTSGAGNSSTGQSASSSAGANSSGTGTSSNSNADQDRFPQQCICCRQTLNSEFEISLHAKFHTKTAETNERTCALCLEPLPSQPESNNTKICDPCLKRHNFPTKLLSMNFLKPATPSLVPTPNHGGSSSAGVVVPPTHGTTIGNSVAVEGRPPLPPPPPTSSGSLQQDSQHPGGVREGSSSALFQCNLCKKPLPTAQKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQTHLPLAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGKAIRPSSFEVASSDEWHTMVQQRSPLGEDDGGGHTGHIKQEQCEPEQEQDGSSSPYHHQKDEDSDDGNDFQQARNGEETNEVDMEQEQEDEDNEQTHAEVNNGGQRDDEDDGRDDAAVGTEECNDAADDDDDDDDDDVEDEEHQERQEEQEDEEEYIEVEHTTLDDGGRGGKQASDERLRRTSNLLINGGKDCSALTATTTATTLPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095829;
90% Identity: iTF_00104586;
80% Identity: -