Basic Information

Insect: Anopheles quadriannulatus
Gene Symbol: L
Assembly: GCA_000349065.1
Location: KB667888.1:296179-322807[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00045 0.022 14.7 3.6 1 23 176 198 176 198 0.97

2 18 0.68 33 4.7 5.7 1 23 204 226 204 226 0.98

3 18 5.6e-06 0.00028 20.7 3.7 1 23 232 254 232 254 0.99

4 18 1.7e-05 0.00083 19.1 0.3 1 23 260 282 260 282 0.98

5 18 7.4 3.6e+02 1.4 0.1 2 23 389 412 388 412 0.78

6 18 0.12 5.7 7.1 0.1 2 23 462 484 461 484 0.96

7 18 0.24 12 6.1 0.2 1 23 821 843 821 843 0.95

8 18 7.6 3.7e+02 1.4 0.6 1 23 880 902 880 902 0.90

9 18 0.00037 0.018 14.9 0.2 1 23 949 972 949 972 0.93

10 18 0.0027 0.13 12.2 0.8 1 23 979 1002 979 1002 0.97

11 18 0.0028 0.13 12.2 1.5 1 23 1034 1056 1034 1057 0.96

12 18 0.49 24 5.1 0.2 1 23 1361 1385 1361 1385 0.91

13 18 0.00068 0.033 14.1 0.2 2 23 1394 1416 1393 1416 0.96

14 18 0.005 0.24 11.4 0.1 1 23 1423 1445 1423 1445 0.98

15 18 2.6 1.3e+02 2.8 1.2 2 20 1453 1471 1453 1474 0.94

16 18 0.0075 0.37 10.8 0.2 1 23 1683 1705 1683 1705 0.96

17 18 0.014 0.68 10.0 0.1 1 20 1715 1734 1715 1738 0.95

18 18 0.042 2 8.5 0.3 1 23 1746 1768 1746 1768 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00045	0.022	14.7	3.6	1	23	176	198	176	198	0.97
2	18	0.68	33	4.7	5.7	1	23	204	226	204	226	0.98
3	18	5.6e-06	0.00028	20.7	3.7	1	23	232	254	232	254	0.99
4	18	1.7e-05	0.00083	19.1	0.3	1	23	260	282	260	282	0.98
5	18	7.4	3.6e+02	1.4	0.1	2	23	389	412	388	412	0.78
6	18	0.12	5.7	7.1	0.1	2	23	462	484	461	484	0.96
7	18	0.24	12	6.1	0.2	1	23	821	843	821	843	0.95
8	18	7.6	3.7e+02	1.4	0.6	1	23	880	902	880	902	0.90
9	18	0.00037	0.018	14.9	0.2	1	23	949	972	949	972	0.93
10	18	0.0027	0.13	12.2	0.8	1	23	979	1002	979	1002	0.97
11	18	0.0028	0.13	12.2	1.5	1	23	1034	1056	1034	1057	0.96
12	18	0.49	24	5.1	0.2	1	23	1361	1385	1361	1385	0.91
13	18	0.00068	0.033	14.1	0.2	2	23	1394	1416	1393	1416	0.96
14	18	0.005	0.24	11.4	0.1	1	23	1423	1445	1423	1445	0.98
15	18	2.6	1.3e+02	2.8	1.2	2	20	1453	1471	1453	1474	0.94
16	18	0.0075	0.37	10.8	0.2	1	23	1683	1705	1683	1705	0.96
17	18	0.014	0.68	10.0	0.1	1	20	1715	1734	1715	1738	0.95
18	18	0.042	2	8.5	0.3	1	23	1746	1768	1746	1768	0.95

Sequence Information

Coding Sequence: ATGGCGCTGAAGATGCTCTACCGTGGCCCGAGCACCAGACTGGAAACGTTGATCGAGAAGATACAGCAAAACACGAACGCTTTCGGTGTCGGCGGCATGATTGCGCCCGGTGCATTGGGTGGTGGTATCGGTGCGATGAAGGAGTTTTCCCTCGGACAAGAGCTATACTCGTCCCACACTTCGTCCAGCTTCTCGCCCTCAATTTCGGACGGCATGACAACGCCCAACTCGATCCCAGAGCCAAACGATGGGCCTGCCACGCTCGATTCGGGCGCCGCCGGTGAAAAGCAATACCGGAACCATCACCCGCATCATCAGCTGCACCCGCGGCATGTGCATCATCTGCATCATCGCCGGGCCGGTGGCATCGGTGGACATTCTTCGACCGGCGGCAAGGAAGGTGGTGGCAAGTCGTCCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGGCCTGGGTGGTGGTGCCGGCAGCAGCACCTACCATTGCCAGTTTTGCGAGAAAACGTTCCCGCGGCTCGGCTATCTCAAGAAGCACGAACAGAGCCACACGGAGCATATGCCATTCAAATGCGAGTACTGTGCCCGACTGTTCAAGCACAAACGATCGCGGGATCGCCATACGAAGCTGCATACGGGCGATCGACGCTATCGCTGTCTGCACTGTGAGGCTGCATTCTCCCGAAGTGATCATCTGAAGATACACATGAAAACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGAGGCTACAATACGGCCGCAGCGCTAACGAGTCATATGCAAAATCACAAAAAGCAGCTGGCCCTGACCGGGAGTCCCAACCTTACGTACAGTCCGCGCTCCACCACAAGCTCCCTGTCGAGTGGAGGAGGAAGTGGTGGTGGTGGTGGTAAGCGAGGGGCAAAGTTCTCGCCCTACTCCAACGACCCACTGATGCTGATGAGCCGCGGCAACTCCAAACTGTCCTCGTCCCTTTCCAAAGCCGCCAGTAATCGAACTCCAACACCTGGGAGTACGGCCGGCGGTGGTGGCAATGCAACCCTAGGAGGTCTGGGAAGTGGTGCGGGAGGTGGTACCGGCCCCAACCATCATCAGCAGGATCTGCTCTCCTGTCCGTACTGTACGCGGACGGATTTTGGGACGCTCGAACAGCTCGGGCTCCATGTGCAGTCGATGCACGGGCATGGTGGTGCTGGTGCATTGGGATTGCTTGCTGGCGACTCCTCAATGTCTTACTTCACACCTGCCGGTGGACGACGTGCAGTGACACCCGATGGGAGCAACGTCCCGCTCTCGCTCGGTGGTCTCAGTCCGTATGCACCGATTAGCTGCGAGTTCTGCACGATGAAGTTCCCAACCGTTCCGCTCATGTTTGCCCATCTCAAGACGGCCCATCTGGATCGGTTGGCTGGCAGTGGTGGTCATCAACGAAGCTCACCATCGAATGGTACCGGCAGTCCGCTCGGGTCACGTCCTCCCAGTGGGTTCCATCCGCTAGACCAGCTGCACTTTAACAAGAGCCTGCTTGGGAATGCTTTCCCCTCCTTCTACGCTGGTGGTGGTGGTGGTGGTTCTTCCAGCAGCCTTGCCGGAATGTCCGGAGGCAGTATTAAAGCGGAGCGCCGGCTAATGGCCGAACGTGATGAAAATGGAAATGAAGAAGAAACGGGAGGCAGAAAGCGGCAGCGCAGAGGAGACGATGGAGAAGATGTTAGGGGGTGCATGTCGAAACGGGACAAGCAGGAAAAGGAGGAGGAACAAGCAATTGAAGGTGATGAGGAGGACGATGAGGATGATGATAATGACGTTGAGGGAGAAGATAATGAGGAAAGTGAGGCTCATGGAGCGGACAATCGATGTGAGGAGTCGATTGACTACAAGGAAGAAGCGATCGATACGAAGATCACACCGATCAAGCAGGAGCGAAAGGAAGAGCCTGCTGAGGGTGAGCCATCTCCTTCGACTTCTGCACGATCGTCTCCCTGTGGTGATTCCCTGGAATTGGCAAGTGGACGTCCCGGAAGTCATCCATCGGGTCGTACAAGTCCAGCAGAGCAACTCACTCCAACAGACCTGAGTCAGCCGAAGATGAAGCGTCTCAAGCTGGAGACGCCTGAAGAAGACCCACTGACCGATGGGGCGGATAGGAAGAGGATGATGGTGACAGGGTCAGCAGCATCTGGAAGATCTCAAACAACTCGCGAGCAACACAAACACCGTGGTCCAGCAACAACCGCTACTGCAGCAAGTCGTCGAGATAGTGAATCAAAAGACTCACACCTCCAGCATGGCTCACTGATGCACTCCTCCTCTTCGGGCAGCAACGTCCAACACTCCCAGCAAATGGGTGCCCCTACTTCTACCGGAACATCATCCCAGCACCACCATCAACCTCCCGGTGCATACCTCTGCAATCAATGCAATGCCGCACTGCCCGATTTCGAATCGTTCCGCACGCACCTCAAGGCACATCTCGAGCAGAGTGCGGCCAGTGCGGCGGCAGCCGCTGCAATGCGACTGTCTGGGGAGCATGCCAACTCGGGCAGTTCCGGAGCATCAGCGTCCCTTTCGCTTACGACCTTCCTCTGTCAGCAGTGTGGTGTAACGTTGAGCTGTCAGGCGGAGTACGAACAGCACACGATTGGCCATTTTCTTGTGACGGCGGTCGAGTATCGATGTCAGGGGTCGACCAGTACTGCAGGCCCTGCTAGCTGCAGTGGTAAGAGCACCTTCGGCAAGCTGGAGGACCTGCACAAACATCTGTACGAAGGGCATATGCAACTCCTCTACAAGTGTACGGTTTGTGGAGAGACGTTCGAATCCAAGGTTCAGGTGCAGGTACACTTTGCCGTGAGTCATTCGGTCGAGGTGAAGCTGTACCGCTGCTCAGCCTGTGCTGAAGTGTTCCGTTCGGAGCGTGATTTTAGGCAACACATTCGAAATCGGCACCTGACGGCGGGTGCTGTACAGTGTATGTTTTGCCGGATGGTTTGCTCGTCCGAGCTTGAGATGCACTTCCATCTTGCGTCGCACGCCAGGAAGTACAAATGTCCAGCCTGTCCGGAGTCGTTCCATGTGGAATTCCTGCTCGATCGGCACATTCAAACGCATCACAGCCAGAAGGAGACGTCCTCACCGAACCGAGGCCGAGAGTCGGCCAACGGTGGCCACAACCTGTCAACTACATCCTCCTGCTCCACCAACTCCACGCCCTCAACGGCCACAGCAGTGTCGTCTACAGCTCAACCGGCCTCAACAACAAACACGGTAACCGGTCTAGACTACCTTCACCTACACGGACAAATGGCGGCAATGGCAGCAGCTGCGGCATGGCCCAGTCTGTACCAAACTGCTGCCAACAAGTTCTACAGCAGCAACCCGCTGCAAGTGGACACACTGTCCCAGTTGAAGCATCCACAGCAGCTTCTGCACGGTTTCTACGACACCATGCTCGGTAAAGCGCAAGCGCAACAGCAGCAGCAGCGTGGTGCATTCCTTCCCGAGCCATCCAGCGGTGGCAAGAAGAACCCCTTCGCTGCTGGCCATTCACCCAATGCCAGTGCGAACGCTACTGCTAATGCACTGCTTGGGCTAGGCTATGGAGGTGCATCACTTACTTCAGGAAACTCCCAACAGCCAAGAACTTCCACGCACAATGGTTCCTCTTCTGGGCTTTACTCCCCCGAGGAAGGTCCTAATGGTGGGTCGAGTGTGGCCACTAGTAGCTCAAAGCTATACTCTCCCATTGCCATGATACAGCGGTACGGTGAAGGTGGTGTACTACATTCCACACCTGGTGCAGTGCCGCCTACTACTACCGGATGTCCTTCCCGCACGGAATCTCCTACACCGAGTGGGCAGCAACTTCTTCTGGCAGCTCACTCCTCGCTAAGTTCACTGCCTGAACATCATCCCGAACAGCAGCAGTCGAGTAATCGAAAGACAGCCCAACAGCAGTCAGGTCCTAAGACATCATCCGGTACAATCACACCACAGCTGATTGCACCCGGCTCGAACAGCTGCTACAGCTGCGGTATCTGCGAACGGTCCGACTTTACCACGGAGAGTGAGGTCCAAACGCATCGCAAGATTGTGCACAACTTGAAAACGGGCGTTAGTTTGCGGTGTGCGTACTGCAACGGAGACTTCCGGTCCAGGAATGAGCTCGAGAACCACATGAAGGTCGCACACAATACGGGCGGTGGCAAGCACAAGTGTTTGATCTGTGACGAAATCTTCCCATCGCCGGCAGTACTTGCCGAGCATAAGCTGACGCACTGTAAGGTGGGTGCTTCGGGACGCTGTTCGCACTGTAGTTTGCCCCTGCCCGATGCTCACACCTTCAAGCAGCATCTGCCAGCTCATCAGCAGATCGGTGGATCATCTTCTGGATCGACAGGAGGAGGCACTATCACATCGACGAATGGCTCCGCAAACGGAGGTACGTCTGGTACAGGTAACTCCTCCACTGGACAGAGTGCGTCCTCTTCGGCCGGAGCTAATTTGAGTGGCACGGGGACAAGTTCCAACACGAATGCTCAGGATCAGGATCGCTTCCCTCAGCAGTGCATCTGTTGCCGGCAAACGCTCAACTCTGAGTTTGAAATTAGTCTTCATGCCAAATTCCACACCAAAACCGCGGAGACTAACGAACGCACGTGTGCTCTCTGCCTGGAGCCGTTACCTTCACAACCCGAGTCCAACACCAAGATCTGTGATCCCTGTCTGAAACGGCACAATTTCCCAACGAAGCTCCTATCGATGAACTTCCTGAAGCCAGCCACCCCATCTCTAGTGCCAACGCCAACCCACGGTGGATCATCTGCAGCCGGTGTTGTTGTACCACCAGCTCACGGTACAACCATTGGTAACAGTGTCGCAGTAGAAGGAAGACCACCACTACCACCACCACCGCCAACATCTTCGGGAAGTCTTCAACAAGACCCACAACACCCGGGTGGCGTACGGGATTGTTCATCCTCTGCACTGTTCCAGTGCAATCTGTGCAAGAAACCGCTACCCTCCGCCCAAAAGCTCCAAGAACATCTGATCGATCATACGTTCGCGGGCTGTGAGGAGCGCGGCTACGTCTGCTACCTGTGCTCGGCCGTGTTTACCTCCTCGGCCGGACTGCAGACCCATCTGCCGCTGGCGCATTCTAACGCGGCCGCCAAACCGTACGACTGTGAGCGGTGCGGTGTGGCGTACTTCTTCCGGGCCGAACTGGAGCACCATCTGATCGATCATGAGCTGGGCAAGGCGATGAGACCCTCCTCCTTTGAGCTAGCTTCGTCCGATGACTGGCACACAATGGTGCAGCAGCGTTCTCCGATGGGTGAGGATGATGGTGGTGGCCACACAGGCCACATCAAGCAGGAACAGTGTGAGCCTGATCAGGAACAGGAAGGATCATCATCACCGTATCACCAGAAAGATGAAGATTCTGATGATGGGAACGACTTCCAACAGCCTAGAAACGGAGAGGAAACAAATGAGGTGGATATGGAGCAGGAACAACAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAGAAGATGAGGAGCACCAGGAACGACAGGAAGAGCAGGAAGATGAAGAAGAGTACATTGAGGTAGAGCACACTACGCTGGATGATGGTGGACGAGGAGGCAAGCAAGCAAGCGACGAACGGCTCCGACGATCGAACCTGTTGATCAATGGCGGGAAGGATTGCTCTGCGCTGACTGCTACCACGACGGCAACCACTCTTCCGGTTGTAACGGCTGCTGAGTGA
Protein Sequence: MALKMLYRGPSTRLETLIEKIQQNTNAFGVGGMIAPGALGGGIGAMKEFSLGQELYSSHTSSSFSPSISDGMTTPNSIPEPNDGPATLDSGAAGEKQYRNHHPHHQLHPRHVHHLHHRRAGGIGGHSSTGGKEGGGKSSXXXXXXXXXXXXXXXXXXXXXXXXXXGLGGGAGSSTYHCQFCEKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGSGGGGGKRGAKFSPYSNDPLMLMSRGNSKLSSSLSKAASNRTPTPGSTAGGGGNATLGGLGSGAGGGTGPNHHQQDLLSCPYCTRTDFGTLEQLGLHVQSMHGHGGAGALGLLAGDSSMSYFTPAGGRRAVTPDGSNVPLSLGGLSPYAPISCEFCTMKFPTVPLMFAHLKTAHLDRLAGSGGHQRSSPSNGTGSPLGSRPPSGFHPLDQLHFNKSLLGNAFPSFYAGGGGGGSSSSLAGMSGGSIKAERRLMAERDENGNEEETGGRKRQRRGDDGEDVRGCMSKRDKQEKEEEQAIEGDEEDDEDDDNDVEGEDNEESEAHGADNRCEESIDYKEEAIDTKITPIKQERKEEPAEGEPSPSTSARSSPCGDSLELASGRPGSHPSGRTSPAEQLTPTDLSQPKMKRLKLETPEEDPLTDGADRKRMMVTGSAASGRSQTTREQHKHRGPATTATAASRRDSESKDSHLQHGSLMHSSSSGSNVQHSQQMGAPTSTGTSSQHHHQPPGAYLCNQCNAALPDFESFRTHLKAHLEQSAASAAAAAAMRLSGEHANSGSSGASASLSLTTFLCQQCGVTLSCQAEYEQHTIGHFLVTAVEYRCQGSTSTAGPASCSGKSTFGKLEDLHKHLYEGHMQLLYKCTVCGETFESKVQVQVHFAVSHSVEVKLYRCSACAEVFRSERDFRQHIRNRHLTAGAVQCMFCRMVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHIQTHHSQKETSSPNRGRESANGGHNLSTTSSCSTNSTPSTATAVSSTAQPASTTNTVTGLDYLHLHGQMAAMAAAAAWPSLYQTAANKFYSSNPLQVDTLSQLKHPQQLLHGFYDTMLGKAQAQQQQQRGAFLPEPSSGGKKNPFAAGHSPNASANATANALLGLGYGGASLTSGNSQQPRTSTHNGSSSGLYSPEEGPNGGSSVATSSSKLYSPIAMIQRYGEGGVLHSTPGAVPPTTTGCPSRTESPTPSGQQLLLAAHSSLSSLPEHHPEQQQSSNRKTAQQQSGPKTSSGTITPQLIAPGSNSCYSCGICERSDFTTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKVAHNTGGGKHKCLICDEIFPSPAVLAEHKLTHCKVGASGRCSHCSLPLPDAHTFKQHLPAHQQIGGSSSGSTGGGTITSTNGSANGGTSGTGNSSTGQSASSSAGANLSGTGTSSNTNAQDQDRFPQQCICCRQTLNSEFEISLHAKFHTKTAETNERTCALCLEPLPSQPESNTKICDPCLKRHNFPTKLLSMNFLKPATPSLVPTPTHGGSSAAGVVVPPAHGTTIGNSVAVEGRPPLPPPPPTSSGSLQQDPQHPGGVRDCSSSALFQCNLCKKPLPSAQKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQTHLPLAHSNAAAKPYDCERCGVAYFFRAELEHHLIDHELGKAMRPSSFELASSDDWHTMVQQRSPMGEDDGGGHTGHIKQEQCEPDQEQEGSSSPYHQKDEDSDDGNDFQQPRNGEETNEVDMEQEQQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEDEEHQERQEEQEDEEEYIEVEHTTLDDGGRGGKQASDERLRRSNLLINGGKDCSALTATTTATTLPVVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095829;
90% Identity: iTF_00104586;
80% Identity: -